TY  - JOUR
A1  - Abdalla, Hassan E.
A1  - Adam, R.
A1  - Aharonian, Felix A.
A1  - Benkhali, F. Ait
A1  - Angüner, Ekrem Oǧuzhan
A1  - Arakawa, M.
A1  - Arcaro, C.
A1  - Armand, C.
A1  - Ashkar, H.
A1  - Backes, M.
A1  - Martins, V. Barbosa
A1  - Barnard, M.
A1  - Becherini, Y.
A1  - Berge, D.
A1  - Bernloehr, K.
A1  - Blackwell, R.
A1  - Böttcher, M.
A1  - Boisson, C.
A1  - Bolmont, J.
A1  - Bonnefoy, S.
A1  - Bregeon, J.
A1  - Breuhaus, M.
A1  - Brun, F.
A1  - Brun, P.
A1  - Bryan, M.
A1  - Büchele, M.
A1  - Bulik, T.
A1  - Bylund, T.
A1  - Capasso, M.
A1  - Caroff, S.
A1  - Carosi, A.
A1  - Casanova, Sabrina
A1  - Cerruti, M.
A1  - Chand, T.
A1  - Chandra, S.
A1  - Chen, A.
A1  - Colafrancesco, S.
A1  - Curylo, M.
A1  - Davids, I. D.
A1  - Deil, C.
A1  - Devin, J.
A1  - DeWilt, P.
A1  - Dirson, L.
A1  - Djannati-Ata, A.
A1  - Dmytriiev, A.
A1  - Donath, A.
A1  - Doroshenko, V
A1  - Dyks, J.
A1  - Egberts, Kathrin
A1  - Emery, G.
A1  - Ernenwein, J-P
A1  - Eschbach, S.
A1  - Feijen, K.
A1  - Fegan, S.
A1  - Fiasson, A.
A1  - Fontaine, G.
A1  - Funk, S.
A1  - Füßling, Matthias
A1  - Gabici, S.
A1  - Gallant, Y. A.
A1  - Gate, F.
A1  - Giavitto, G.
A1  - Glawion, D.
A1  - Glicenstein, J. F.
A1  - Gottschall, D.
A1  - Grondin, M-H
A1  - Hahn, J.
A1  - Haupt, M.
A1  - Heinzelmann, G.
A1  - Henri, G.
A1  - Hermann, G.
A1  - Hinton, James Anthony
A1  - Hofmann, W.
A1  - Hoischen, Clemens
A1  - Holch, Tim Lukas
A1  - Holler, M.
A1  - Horns, D.
A1  - Huber, D.
A1  - Iwasaki, H.
A1  - Jamrozy, M.
A1  - Jankowsky, D.
A1  - Jankowsky, F.
A1  - Jardin-Blicq, A.
A1  - Jung-Richardt, I
A1  - Kastendieck, M. A.
A1  - Katarzynski, K.
A1  - Katsuragawa, M.
A1  - Katz, U.
A1  - Khangulyan, D.
A1  - Khelifi, B.
A1  - King, J.
A1  - Klepser, S.
A1  - Kluzniak, W.
A1  - Komin, Nu
A1  - Kosack, K.
A1  - Kostunin, D.
A1  - Kraus, M.
A1  - Lamanna, G.
A1  - Lau, J.
A1  - Lemiere, A.
A1  - Lemoine-Goumard, M.
A1  - Lenain, J-P
A1  - Leser, Eva
A1  - Levy, C.
A1  - Lohse, T.
A1  - Lypova, I
A1  - Mackey, J.
A1  - Majumdar, J.
A1  - Malyshev, D.
A1  - Marandon, V
A1  - Marcowith, Alexandre
A1  - Mares, A.
A1  - Mariaud, C.
A1  - Marti-Devesa, G.
A1  - Marx, R.
A1  - Maurin, G.
A1  - Meintjes, P. J.
A1  - Mitchell, A. M. W.
A1  - Moderski, R.
A1  - Mohamed, M.
A1  - Mohrmann, L.
A1  - Moore, C.
A1  - Moulin, Emmanuel
A1  - Muller, J.
A1  - Murach, T.
A1  - Nakashima, S.
A1  - de Naurois, M.
A1  - Ndiyavala, H.
A1  - Niederwanger, F.
A1  - Niemiec, J.
A1  - Oakes, L.
A1  - Odaka, H.
A1  - Ohm, S.
A1  - Wilhelmi, E. de Ona
A1  - Ostrowski, M.
A1  - Oya, I
A1  - Panter, M.
A1  - Parsons, R. D.
A1  - Perennes, C.
A1  - Petrucci, P-O
A1  - Peyaud, B.
A1  - Piel, Q.
A1  - Pita, S.
A1  - Poireau, V
A1  - Priyana Noel, A.
A1  - Prokhorov, D. A.
A1  - Prokoph, H.
A1  - Pühlhofer, G.
A1  - Punch, M.
A1  - Quirrenbach, A.
A1  - Raab, S.
A1  - Rauth, R.
A1  - Reimer, A.
A1  - Reimer, O.
A1  - Remy, Q.
A1  - Renaud, M.
A1  - Rieger, F.
A1  - Rinchiuso, L.
A1  - Romoli, C.
A1  - Rowell, G.
A1  - Rudak, B.
A1  - Ruiz-Velasco, E.
A1  - Sahakian, V
A1  - Saito, S.
A1  - Sanchez, David M.
A1  - Santangelo, Andrea
A1  - Sasaki, M.
A1  - Schlickeiser, R.
A1  - Schüssler, F.
A1  - Schulz, A.
A1  - Schutte, H.
A1  - Schwanke, U.
A1  - Schwemmer, S.
A1  - Seglar-Arroyo, M.
A1  - Senniappan, M.
A1  - Seyffert, A. S.
A1  - Shafi, N.
A1  - Shiningayamwe, K.
A1  - Simoni, R.
A1  - Sinha, A.
A1  - Sol, H.
A1  - Specovius, A.
A1  - Spir-Jacob, M.
A1  - Stawarz, L.
A1  - Steenkamp, R.
A1  - Stegmann, Christian
A1  - Steppa, Constantin Beverly
A1  - Takahashi, T.
A1  - Tavernier, T.
A1  - Taylor, A. M.
A1  - Terrier, R.
A1  - Tiziani, D.
A1  - Tluczykont, M.
A1  - Trichard, C.
A1  - Tsirou, M.
A1  - Tsuji, N.
A1  - Tuffs, R.
A1  - Uchiyama, Y.
A1  - van Der Walt, D. J.
A1  - van Eldik, C.
A1  - van Rensburg, C.
A1  - van Soelen, B.
A1  - Vasileiadis, G.
A1  - Veh, J.
A1  - Venter, C.
A1  - Vincent, P.
A1  - Vink, J.
A1  - Voisin, F.
A1  - Voelk, H. J.
A1  - Vuillaume, T.
A1  - Wadiasingh, Z.
A1  - Wagner, S. J.
A1  - White, R.
A1  - Wierzcholska, A.
A1  - Yang, R.
A1  - Yoneda, H.
A1  - Zacharias, Michael
A1  - Zanin, R.
A1  - Zdziarski, A. A.
A1  - Zech, Alraune
A1  - Ziegler, A.
A1  - Zorn, J.
A1  - Zywucka, N.
A1  - Meyer, M.
T1  - Constraints on the emission region of 3C 279 during strong flares in 2014 and 2015 through VHE gamma-ray observations with HESS
JF  - Astronomy and astrophysics : an international weekly journal
N2  - The flat spectrum radio quasar 3C 279 is known to exhibit pronounced variability in the high-energy (100MeV < E < 100 GeV) gamma-ray band, which is continuously monitored with Fermi-LAT. During two periods of high activity in April 2014 and June 2015 target-of-opportunity observations were undertaken with the High Energy Stereoscopic System (H.E.S.S.) in the very-high-energy (VHE, E > 100 GeV) gamma-ray domain. While the observation in 2014 provides an upper limit, the observation in 2015 results in a signal with 8 : 7 sigma significance above an energy threshold of 66 GeV. No VHE variability was detected during the 2015 observations. The VHE photon spectrum is soft and described by a power-law index of 4.2 +/- 0.3. The H.E.S.S. data along with a detailed and contemporaneous multiwavelength data set provide constraints on the physical parameters of the emission region. The minimum distance of the emission region from the central black hole was estimated using two plausible geometries of the broad-line region and three potential intrinsic spectra. The emission region is confidently placed at r greater than or similar to 1 : 7 X 1017 cm from the black hole, that is beyond the assumed distance of the broad-line region. Time-dependent leptonic and lepto-hadronic one-zone models were used to describe the evolution of the 2015 flare. Neither model can fully reproduce the observations, despite testing various parameter sets. Furthermore, the H.E.S.S. data were used to derive constraints on Lorentz invariance violation given the large redshift of 3C 279.
KW  - radiation mechanisms: non-thermal
KW  - quasars: individual: 3C 279
KW  - galaxies: active
KW  - relativistic processes
Y1  - 2019
U6  - https://doi.org/10.1051/0004-6361/201935704
SN  - 1432-0746
VL  - 627
PB  - EDP Sciences
CY  - Les Ulis
ER  - 
TY  - GEN
A1  - Best, Robert B.
A1  - Zheng, Wenwei
A1  - Borgia, Alessandro
A1  - Buholzer, Karin
A1  - Borgia, Madeleine B.
A1  - Hofmann, Hagen
A1  - Soranno, Andrea
A1  - Nettels, Daniel
A1  - Gast, Klaus
A1  - Grishaev, Alexander
A1  - Schuler, Benjamin
T1  - Comment on "Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water"
T2  - Science
N2  - Riback et al. (Reports, 13 October 2017, p. 238) used small-angle x-ray scattering (SAXS) experiments to infer a degree of compaction for unfolded proteins in water versus chemical denaturant that is highly consistent with the results from Forster resonance energy transfer (FRET) experiments. There is thus no "contradiction" between the two methods, nor evidence to support their claim that commonly used FRET fluorophores cause protein compaction.
Y1  - 2018
U6  - https://doi.org/10.1126/science.aar7101
SN  - 0036-8075
SN  - 1095-9203
VL  - 361
IS  - 6405
PB  - American Assoc. for the Advancement of Science
CY  - Washington
ER  - 
TY  - JOUR
A1  - Borgia, Alessandro
A1  - Zheng, Wenwei
A1  - Buholzer, Karin
A1  - Borgia, Madeleine B.
A1  - Schüler, Anja
A1  - Hofmann, Hagen
A1  - Soranno, Andrea
A1  - Nettels, Daniel
A1  - Gast, Klaus
A1  - Grishaev, Alexander
A1  - Best, Robert B.
A1  - Schuler, Benjamin
T1  - Consistent View of Polypeptide Chain Expansion in Chemical Denaturants from Multiple Experimental Methods
JF  - Journal of the American Chemical Society
N2  - There has been a long-standing controversy regarding the effect of chemical denaturants on the dimensions of unfolded and intrinsically disordered proteins: A wide range of experimental techniques suggest that polypeptide chains expand with increasing denaturant concentration, but several studies using small-angle X-ray scattering (SAXS) have reported no: such increase of the radius of gyration (R-g). This inconsistency challenges our current understanding of the mechanism of chemical denaturants, which are widely employed to investigate protein folding and stability. Here, we use a combination Of single-molecule Forster resonance energy transfer (FRET), SAXS, dynamic light scattering (DLS), and two-focus fluorescence correlation spectroscopy (2f-FCS) to characterize the denaturant dependence of the unfolded state of the spectrin domain R17 and the intrinsically disordered protein ACTR in two different denaturants. Standard analysis of the primary data clearly indicates an expansion of the unfolded state with increasing denaturant concentration irrespective of the protein, denaturant, or experimental method used. This is the first case in which SAXS and FRET have yielded even qualitatively consistent results regarding expansion in denaturant when applied to the same proteins. To more directly illustrate this self-consistency, we used both SAXS and FRET data in a Bayesian procedure to refine structural ensembles representative of the observed unfolded state. This analysis demonstrates that both of these experimental probes are compatible with a common ensemble of protein configurations for each denaturant concentration. Furthermore, the resulting ensembles reproduce the trend of increasing hydrodynamic radius, with denaturant concentration obtained by 2f-FCS,and DLS. We were thus able to reconcile the results from all four experimental techniques quantitatively, to obtain a comprehensive structural picture of denaturant;induced unfolded state expansion, and to identify the Most likely sources of earlier discrepancies.
Y1  - 2016
U6  - https://doi.org/10.1021/jacs.6b05917
SN  - 0002-7863
VL  - 138
SP  - 11714
EP  - 11726
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - BOOK
A1  - Finkelmann, B.
A1  - Hofmann, H.
A1  - Koch, Uwe
A1  - Telschow, Stephan
T1  - 10 Jahre Projekt "Sport mit Aussiedlern"
BT  - Zehn Jahre Projekt "Sport mit Aussiedlern"
Y1  - 1998
PB  - Deutscher Sportbund
CY  - Frankfurt am Main
ER  - 
TY  - JOUR
A1  - Nettels, Daniel
A1  - Müller-Späth, Sonja
A1  - Küster, Frank
A1  - Hofmann, Hagen
A1  - Haenni, Domminik
A1  - Rüegger, Stefan
A1  - Reymond, Luc
A1  - Hoffmann, Armin S.
A1  - Kubelka, Jan
A1  - Heinz, Benjamin
A1  - Gast, Klaus
A1  - Best, Robert B.
A1  - Schuler, Benjamin
T1  - Single-molecule spectroscopy of the temperature-induced collapse of unfolded proteins
N2  - We used single-molecule FRET in combination with other biophysical methods and molecular simulations to investigate the effect of temperature on the dimensions of unfolded proteins. With singlemolecule FRET, this question can be addressed even under nearnative conditions, where most molecules are folded, allowing us to probe a wide range of denaturant concentrations and temperatures. We find a compaction of the unfolded state of a small cold shock protein with increasing temperature in both the presence and the absence of denaturant, with good agreement between the results from single-molecule FRET and dynamic light scattering. Although dissociation of denaturant from the polypeptide chain with increasing temperature accounts for part of the compaction, the results indicate an important role for additional temperaturedependent interactions within the unfolded chain. The observation of a collapse of a similar extent in the extremely hydrophilic, intrinsically disordered protein prothymosin suggests that the hydrophobic effect is not the sole source of the underlying interactions. Circular dichroism spectroscopy and replica exchange molecular dynamics simulations in explicit water show changes in secondary structure content with increasing temperature and suggest a contribution of intramolecular hydrogen bonding to unfolded state collapse.
Y1  - 2009
UR  - http://www.pnas.org/content/106/49/20740.full.pdf+html
SN  - 0027-8424
ER  - 
TY  - CHAP
A1  - Bilitewski, Ursula
A1  - Kaba, H.
A1  - Heilmann, Katja
A1  - Mayer, Yvonne
A1  - Hofmann, B.
A1  - Mueller, P.
A1  - van den Heuvel, J.
T1  - Monoclonal antibodies against specific peptides derived from the 1,3-beta-glucosyltransferase Bgl2p allow detection of Candida albicans cells
T2  - Mycoses : diagnosis, therapy and prophylaxis of fungal diseases
Y1  - 2013
SN  - 0933-7407
VL  - 56
IS  - 1
SP  - 27
EP  - 27
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Föllmi, Karl B.
A1  - Hofmann, Helene
A1  - Chiaradia, Massimo
A1  - de Kaenel, Eric
A1  - Frijia, Gianluca
A1  - Parente, Mariano
T1  - Miocene phosphate-rich sediments in Salento (southern Italy)
JF  - Sedimentary geology : international journal of applied and regional sedimentology
N2  - The upper Middle to lower Upper Miocene (Serravallian to Tortonian) sedimentary succession in Salento (southern Italy) includes glauconite- and phosphate-rich deposits, which are associated with pelagic micrite. In Baia del Ciolo and Marittima (southern Salento), the succession is composed of shallow-water platform carbonates of Late Oligocene age (Chattian; Porto Badisco Formation), which are overlain by a 20- to 30-cm-thick level of glauconite-rich micrite with abundant reworked particles and fossils of the underlying Porto Badisco Formation. This interval is in turn covered by an up to 15 cm thick phosphatic crust ("Livello ad Aturia"), which itself is overlain either by a hemipelagic chalk-like carbonate of Middle to Late Miocene age ("Pietra Leccese"; Marittima) or directly by a micrite of Late Miocene age (Messinian; Novaglie Formation; Baia del Ciolo), which shallows upwards into a shallow-water platform carbonate. A large hiatus is present in this succession, which likely includes the Lower and lower Middle Miocene. In the region of Lecce, two discrete levels enriched in glauconite and phosphate-each associated with a major discontinuity-occur within the Pietra Leccese. The strontium-isotope ages derived on phosphate nodules and phosphatized and non-phosphatized fossils and calcareous nannofossil ages indicate a time interval of phosphogenesis between 13.5 and 7.5 Ma, with two clusters at 12 and 10.5 Ma. The glauconite and phosphate-rich sediments resulted from a current-dominated regime, which was characterized by low overall sedimentation rates, erosion and sediment reworking, and authigenesis. This regime was likely related to a generally westward-directed bottom current, which was forced to upwell once it arrived at the western border of the eastern Mediterranean basin. The timing of the principal phosphogenic phases can only partly be correlated to those of other occurrences in this part of the Mediterranean (Malta, Gozo, southern Sicily, Matese, Latium-Abruzzi platform). The partial diachrony in phosphogenesis may express the effect of lateral switching in and/or focusing of upwelling zones. (C) 2015 Elsevier B.V. All rights reserved.
KW  - Miocene
KW  - Salento
KW  - Italy
KW  - Phosphogenesis
KW  - Paleoceanography
Y1  - 2015
U6  - https://doi.org/10.1016/j.sedgeo.2015.07.009
SN  - 0037-0738
SN  - 1879-0968
VL  - 327
SP  - 55
EP  - 71
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Moser, Othmar
A1  - Mueller, Alexander
A1  - Tschakert, Gerhard
A1  - Koehler, Gerd
A1  - Lawrence, Jimmy B.
A1  - Groeschl, Werner
A1  - Pieber, Thomas R.
A1  - Bracken, Richard M.
A1  - Hofmann, Peter
T1  - Exercise Prescription in Type 1 Diabetes: Should We Use Percentages of Maximum Heart Rate?
T2  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
Y1  - 2017
U6  - https://doi.org/10.1249/01.mss.0000519798.35679.cf
SN  - 0195-9131
SN  - 1530-0315
VL  - 49
SP  - 1020
EP  - 1020
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - JOUR
A1  - Briesemeister, Benny B.
A1  - Hofmann, Markus J.
A1  - Kuchinke, Lars
A1  - Jacobs, Arthur M.
T1  - The BAWL databases in research on emotional word processing
JF  - Potsdam cognitive science series
N2  - Inhalt: Introduction A two-dimensional affective space: Valence and arousal effects in word processing Higher dimensional affective space: a role of discrete emotions in word processing? A direct comparison of the affective space models References
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62377
SN  - 2190-4545
SN  - 2190-4553
IS  - 3
SP  - 61
EP  - 66
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  - 
TY  - BOOK
A1  - Baayen, Rolf Harald
A1  - Kresse, Lara
A1  - Kirschner, Stefan
A1  - Dipper, Stefanie
A1  - Belke, Eva
A1  - Keuleers, Emmanuel
A1  - Brysbaert, Marc
A1  - New, Boris
A1  - Heister, Julian
A1  - Kliegl, Reinhold
A1  - Zinsmeister, Heike
A1  - Smolka, Eva
A1  - Briesemeister, Benny B.
A1  - Hofmann, Markus J.
A1  - Kuchinke, Lars
A1  - Jacobs, Arthur M.
ED  - Würzner, Kay-Michael
ED  - Pohl, Edmund
T1  - Lexical resources in psycholinguistic research
N2  - Experimental and quantitative research in the field of human language processing and production strongly depends on the quality of the underlying language material: beside its size, representativeness, variety and balance have been discussed as important factors which influence design, analysis and interpretation of experiments and their results. This volume brings together creators and users of both general purpose and specialized lexical resources which are used in psychology, psycholinguistics, neurolinguistics and cognitive research. It aims to be a forum to report experiences and results, review problems and discuss perspectives of any linguistic data used in the field.
N2  - Experimentelle und quantitative Forschung im Bereich der menschlichen Sprachverarbeitung und -produktion hängt wesentlich von der Qualität des zugrundeliegenden Sprachmaterials ab: Neben dessen Umfang wurden auch Repräsentativität, Vielfalt und Ausgewogenheit als wichtige Einflüsse auf Design, Analyse und Interpretation entsprechender Experimente und deren Ergebnisse diskutiert. Der vorliegende Band enthält Arbeiten von Entwicklern und Anwendern sowohl allgemeiner als auch spezialisierter lexikalischer Ressourcen aus den Bereichen Psychologie, Psycho-, Neurolinguistik und Kongitionswissenschaften. Ziel ist es anhand der dargestellten Ergebnisse Probleme und Perspektiven bei der Arbeit mit linguistischen Daten aufzuzeigen.
T3  - Potsdam Cognitive Science Series - 3 
KW  - Psychologie
KW  - Psycholinguistik
KW  - Kognitionswissenschaften
KW  - lexikalische Datenbanken
KW  - menschliche Sprachverarbeitung
KW  - Worterkennung
KW  - Psychology
KW  - psycholinguistics
KW  - cognitive sciences
KW  - lexical databases
KW  - human language processing
KW  - word recognition
Y1  - 2012
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-59100
SN  - 978-3-86956-178-3
SN  - 2190-4545
SN  - 2190-4553
PB  - Universitätsverlag Potsdam
CY  - Potsdam
ER  -