TY - JOUR A1 - Hofmann, Markus J. A1 - Dambacher, Michael A1 - Jacobs, Arthur M. A1 - Kliegl, Reinhold A1 - Radach, Ralph A1 - Kuchinke, Lars A1 - Plichta, Michael M. A1 - Fallgatter, Andreas J. A1 - Herrmann, Martin J. T1 - Occipital and orbitofrontal hemodynamics during naturally paced reading: An fNIRS study JF - NeuroImage : a journal of brain function N2 - Humans typically read at incredibly fast rates, because they predict likely occurring words from a given context. Here, we used functional near-infrared spectroscopy (fNIRS) to track the ultra-rapid hemodynamic responses of words presented every 280 ms in a naturally paced sentence context. We found a lower occipital deoxygenation to unpredictable than to predictable words. The greater hemodynamic responses to unexpected words suggest that the visual features of expected words have been pre-activated previous to stimulus presentation. Second, we tested opposing theoretical proposals about the role of the medial orbitofrontal cortex (OFC): Either OFC may respond to the breach of expectation; or OFC is activated when the present stimulus matches the prediction. A significant interaction between word frequency and predictability indicated OFC responses to breaches of expectation for low- but not for high-frequency words: OFC is sensitive to both, bottom-up processing as mediated by word frequency, as well as top-down predictions. Particularly, when a rare word is unpredictable, OFC becomes active. Finally, we discuss how a high temporal resolution can help future studies to disentangle the hemodynamic responses of single trials in such an ultra-rapid event succession as naturally paced reading. (C) 2014 Elsevier Inc. All rights reserved. KW - Frontopolar KW - Orbitofrontal KW - Bayesian brain KW - Predictive coding KW - Cloze probability Y1 - 2014 U6 - https://doi.org/10.1016/j.neuroimage.2014.03.014 SN - 1053-8119 SN - 1095-9572 VL - 94 SP - 193 EP - 202 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Dambacher, Michael A1 - Kliegl, Reinhold A1 - Hofmann, Markus A1 - Jacobs, Arthur M. T1 - Frequency and predictability effects on event-related potentials during reading N2 - Effects of frequency, predictability, and position of words on event-related potentials were assessed during word-by-word sentence reading in 48 subjects in an early and in a late time window corresponding to P200 and N400. Repeated measures multiple regression analyses revealed a P200 effect in the high-frequency range also the P200 was larger on words at the beginning and end of sentences than on words in the middle of sentences (i.e., a quadratic effect of word position). Predictability strongly affected the N400 component; the effect was stronger for low than for high- frequency words. The P200 frequency effect indicates that high-frequency words are lexically accessed very fast, independent of context information. Effects on the N400 suggest that predictability strongly moderates the late access especially of low-frequency words. Thus, contextual facilitation on the N400 appears to reflect both lexical and post- lexical stages of word recognition, questioning a strict classification into lexical and post-lexical processes. Y1 - 2006 UR - http://www.sciencedirect.com/science/journal/00068993 U6 - https://doi.org/10.1016/j.brainres.2006.02.010 SN - 0006-8993 ER - TY - JOUR A1 - Kliegl, Reinhold A1 - Dambacher, Michael A1 - Dimigen, Olaf A1 - Jacobs, Arthur M. A1 - Sommer, Werner T1 - Eye movements and brain electric potentials during reading JF - Psychological research : an international journal of perception, attention, memory, and action N2 - The development of theories and computational models of reading requires an understanding of processing constraints, in particular of timelines related to word recognition and oculomotor control. Timelines of word recognition are usually determined with event-related potentials (ERPs) recorded under conditions of serial visual presentation (SVP) of words; timelines of oculomotor control are derived from parameters of eye movements (EMs) during natural reading. We describe two strategies to integrate these approaches. One is to collect ERPs and EMs in separate SVP and natural reading experiments for the same experimental material (but different subjects). The other strategy is to co-register EMs and ERPs during natural reading from the same subjects. Both strategies yield data that allow us to determine how lexical properties influence ERPs (e.g., the N400 component) and EMs (e.g., fixation durations) across neighboring words. We review our recent research on the effects of frequency and predictability of words on both EM and ERP measures with reference to current models of eye-movement control during reading. Results are in support of the proposition that lexical access is distributed across several fixations and across brain-electric potentials measured on neighboring words. Y1 - 2012 U6 - https://doi.org/10.1007/s00426-011-0376-x SN - 0340-0727 VL - 76 IS - 2 SP - 145 EP - 158 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Dambacher, Michael A1 - Dimigen, Olaf A1 - Braun, Mario A1 - Wille, Kristin A1 - Jacobs, Arthur M. A1 - Kliegl, Reinhold T1 - Stimulus onset asynchrony and the timeline of word recognition: Event-related potentials during sentence reading JF - Neuropsychologia : an international journal in behavioural and cognitive neuroscience N2 - Three ERP experiments examined the effect of word presentation rate (i.e., stimulus onset asynchrony, SOA) on the time course of word frequency and predictability effects in sentence reading. In Experiments 1 and 2, sentences were presented word-by-word in the screen center at an SOA of 700 and 490 ms, respectively. While these rates are typical for psycholinguistic ERP research, natural reading happens at a considerably faster pace. Accordingly. Experiment 3 employed a near-normal SOA of 280 ms, which approximated the rate of normal reading. Main results can be summarized as follows: (1) The onset latency of early frequency effects decreases gradually with increasing presentation rates. (2) An early interaction between top-down and bottom-up processing is observed only under a near-normal SOA. (3) N400 predictability effects occur later and are smaller at a near-normal (i.e., high) presentation rate than at the lower rates commonly used in ERP experiments. (4) ERP morphology is different at the shortest compared to longer SOAs. Together, the results point to a special role of a near-normal presentation rate for visual word recognition and therefore suggest that SOA should be taken into account in research of natural reading. KW - Word recognition KW - Sentence reading KW - Stimulus onset asynchrony (SOA) KW - Frequency KW - Predictability KW - Event-related potentials (ERPs) Y1 - 2012 U6 - https://doi.org/10.1016/j.neuropsychologia.2012.04.011 SN - 0028-3932 VL - 50 IS - 8 SP - 1852 EP - 1870 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Dimigen, Olaf A1 - Sommer, Werner A1 - Hohlfeld, Annette A1 - Jacobs, Arthur M. A1 - Kliegl, Reinhold T1 - Coregistration of eye movements and EEG in natural reading analyses and review JF - Journal of experimental psychology : General N2 - Brain-electric correlates of reading have traditionally been studied with word-by-word presentation, a condition that eliminates important aspects of the normal reading process and precludes direct comparisons between neural activity and oculomotor behavior. In the present study, we investigated effects of word predictability on eye movements (EM) and fixation-related brain potentials (FRPs) during natural sentence reading. Electroencephalogram (EEG) and EM (via video-based eye tracking) were recorded simultaneously while subjects read heterogeneous German sentences, moving their eyes freely over the text. FRPs were time-locked to first-pass reading fixations and analyzed according to the cloze probability of the currently fixated word. We replicated robust effects of word predictability on EMs and the N400 component in FRPs. The data were then used to model the relation among fixation duration, gaze duration, and N400 amplitude, and to trace the time course of EEG effects relative to effects in EM behavior. In an extended Methodological Discussion section, we review 4 technical and data-analytical problems that need to be addressed when FRPs are recorded in free-viewing situations (such as reading, visual search, or scene perception) and propose solutions. Results suggest that EEG recordings during normal vision are feasible and useful to consolidate findings from EEG and eye-tracking studies. KW - EEG KW - eye tracking KW - fixation-related potentials KW - artifact correction KW - natural viewing Y1 - 2011 U6 - https://doi.org/10.1037/a0023885 SN - 0096-3445 VL - 140 IS - 4 SP - 552 EP - 572 PB - American Psychological Association CY - Washington ER -