TY  - GEN
A1  - Polzin, Amin
A1  - Rassaf, Tienush
A1  - Boehm, Andreas
A1  - Lueth, Anja
A1  - Kleuser, Burkhard
A1  - Zeus, Tobias
A1  - Kelm, Malte
A1  - Kroemer, Heyo K.
A1  - Schroer, Karsten
A1  - Rauch, Bernhard H.
T1  - Aspirin inhibits release of platelet-derived sphingosine-1-phosphate in
 acute myocardial infarction
T2  - INTERNATIONAL JOURNAL OF CARDIOLOGY
KW  - Sphingosine-1-phosphate
KW  - Acute coronary syndrome
KW  - Platelets
KW  - Aspirin
Y1  - 2013
U6  - https://doi.org/10.1016/j.ijcard.2013.10.050
SN  - 0167-5273
SN  - 1874-1754
VL  - 170
IS  - 2
SP  - E23
EP  - E24
PB  - ELSEVIER IRELAND LTD
CY  - CLARE
ER  - 
TY  - CHAP
A1  - Boehm, Andreas
A1  - Polzin, A.
A1  - Lueth, Anja
A1  - Kleuser, Burkhard
A1  - Rassaf, T.
A1  - Kelm, M.
A1  - Kroemer, H. K.
A1  - Schroer, K.
A1  - Rauch, B. H.
T1  - The release of sphingosine-1-phosphate from human platelets during acute coronary syndrome is attenuated by aspirin
T2  - NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY
Y1  - 2012
SN  - 0028-1298
VL  - 385
SP  - 12
EP  - 12
PB  - Springer
CY  - New York
ER  - 
TY  - JOUR
A1  - Wells, Konstans
A1  - O'Hara, R. B.
A1  - Boehm, S. M.
A1  - Gockel, Sonja
A1  - Hemp, Andreas
A1  - Renner, S. C.
A1  - Pfeiffer, S.
A1  - Boehning-Gaese, Katrin
A1  - Kalko, Elisabeth K. V.
T1  - Trait-dependent occupancy dynamics of birds in temperate forest landscapes fine-scale observations in a hierarchical multi-species framework
JF  - Animal conservation
N2  - Silvicultural practices lead to changes in forest composition and structure and may impact species diversity from the overall regional species pool to stand-level species occurrence. We explored to what extent fine-scale occupancy patterns in differently managed forest stands are driven by environment and ecological traits in three regions in Germany using a multi-species hierarchical model. We tested for the possible impact of environmental variables and ecological traits on occupancy dynamics in a joint modelling exercise while taking possible variation in coefficient estimates over years and plots into account. Bird species richness differed across regions and years, and trends in species richness across years were different in the three regions. On the species level, forest management affected occupancy of species in all regions, but only 35% of the total assemblage-level variation in occurrence probability was explained by either forest type and successional stage and <?1% by forest edge. On the assemblage level, bird occurrence decreased with body mass in all regions. Species with smaller breeding ranges had lower occurrence probabilities in one region, while later spring arrival decreased occurrence probabilities in the two other regions. Spatial variation in the effect size of trait covariates such as species phylogeny and breeding strata showed that variation in patch occupancy due to fine-scale differences in forest management is, to some extent, predictable from ecological traits. Our results show that environmental factors and ecological traits jointly predict variation in bird occupancy patterns and their response to forest management. Observations at the fine scale of forest stands, at which conservation efforts can be arranged along with forest management practices in heterogeneous environments, have been shown to provide meaningful insights despite the difficulties involved in monitoring mobile organisms such as birds at the plot level.
KW  - bird community
KW  - biodiversity conservation
KW  - forest management
KW  - functional traits
KW  - multi-species hierarchical modelling
KW  - patch occupancy
KW  - silviculture
Y1  - 2012
U6  - https://doi.org/10.1111/j.1469-1795.2012.00560.x
SN  - 1367-9430
VL  - 15
IS  - 6
SP  - 626
EP  - 637
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Boehm, Stanislav
A1  - Tomašciková, Jana
A1  - Imrich, Ján
A1  - Danihel, Ivan
A1  - Kristian, Pavol
A1  - Koch, Andreas
A1  - Kleinpeter, Erich
A1  - Klika, Karel D.
T1  - Computational study to assign structure, tautomerism, E/Z and s-cis/s-trans isomerism, pi-delocalization, partial aromaticity, and the ring size of 1,3-thiazolidin-4-ones and 1,3-thiazin-4-ones formed from thiosemicarbazides
N2  - A set of structures encompassing 1-(9-acridinyl)thiosemicarbazide and its 2-methyl derivative together with their various tautomeric structures; the 5-membered ring 1,3-thiazolidin-4-one products resulting from the reaction of 1- (9-acridinyl)thiosemicarbazide and its 2-methyl derivative with dimethyl acetylenedicarboxylate (DMAD) together with the alternative 6-membered ring isomeric reaction products as well as other potential isomeric structures; and the 6- membered ring 1,3-thiazin-4-one product resulting from the reaction of 2-methyl-1-(9-acridinyl)thiosemicarbazide with methyl propiolate (MP) together with the alternative 5-membered ring isomeric reaction product were all extensively studied by molecular modeling calculations using DFT at the B3LYP/6-31G(d,p) level of theory. The ring-chain tautomerism of the thiosemicarbazides, the regio- and stereoselectivity of the reactions, the adopted conformations and E/Z configurations of the products, the prototropic tautomerism of all the compounds, and the reasons for the predominance of the s-cis conformation of the Z configuration of the 1,3-thiazolidin-4-one product in particular were all extensively analyzed. Comparison of the modeled structures were also made to the 1,3-thiazolidin-4-one and 1,3-thiazin-4-one structures of the methyl derivative as well as 1-(9-acridinyl)thiosemicarbazide available from X-ray crystallographic analysis. Tactics utilizing spectroscopic methods {1R frequencies (nu) and NMR chemical shifts (delta), scalar coupling constants (J), and NOEs (eta)} in conjunction with molecular modeling calculations of the spectral parameters (frequency calculations (v) and NMR 6 using the GIAO method and J by calculation of the Fermi contact term) were evaluated in terms of proving 5- or 6-membered ring formation.
Y1  - 2009
UR  - http://www.sciencedirect.com/science/journal/01661280
U6  - https://doi.org/10.1016/j.theochem.2009.09.019
SN  - 0166-1280
ER  -