TY  - JOUR
A1  - Schweigert, Florian J.
A1  - Wirth, Kerstin
A1  - Raila, Jens
T1  - Characterization of the microheterogeneity of transthyretin in plasma and urine using SELDI-TOF-MS immunoassay
Y1  - 2004
ER  - 
TY  - JOUR
A1  - Raila, Jens
A1  - Wirth, Kerstin
A1  - Chen, Frank
A1  - Büscer, Ulrich
A1  - Dudenhausen, Joachim W.
A1  - Schweigert, Florian J.
T1  - Excretion of vitamin A in urine of women during Normal pregnancy and pregnancy complications
N2  - Background/Aims: The renal function, including the excretion of low-molecular-weight proteins, changes during pregnancy and may cause a urinary excretion of retinol-binding protein (RBP). Whether it is accompanied by a substantial loss of vitamin A ( retinol) has not been established yet. We therefore determined the excretion of retinol and RBP in urine of pregnant women. Methods: The study involved analyses of urine samples from 40 healthy pregnant women and 29 women with pregnancy complications during the third trimester. Analyses of plasma and urine of 7 healthy women and 5 women with pregnancy complications were also carried out 6 weeks antepartum, at time of delivery and 1 week postpartum. Results: Urinary retinol was higher in women who suffered from pregnancy disorders with an influence on maternal metabolism ( p < 0.01). RBP was excreted at substantial concentrations in the urine of all 69 women, but there were no differences between the groups. Women with a concomitant excretion of retinol had higher levels of urinary RBP than those without a retinol excretion ( p < 0.05). Differences in plasma retinol and RBP were not significant. Conclusion: The excretion of urinary retinol may increase significantly during pregnancy complications, which needs further clarification to which extent this condition may negatively affect the vitamin A status in such women. Copyright (C) 2004 S. Karger AG, Basel
Y1  - 2004
SN  - 0250-6807
ER  - 
TY  - BOOK
A1  - Raila, Jens
A1  - Wirth, Kerstin
A1  - Büscher, Ulrich
A1  - Dudenhausen, Joachim W.
A1  - Schweigert, Florian J.
T1  - Einfluss normaler und pathologischer Schwangerschaftsverläufe auf die renale Ausscheidung von Vitamin A und Retinol-Bindungsprotein
Y1  - 2001
ER  -