TY  - JOUR
A1  - Hirschmueller, Anja
A1  - Frey, Victoria
A1  - Konstantinidis, Lukas
A1  - Baur, Heiner
A1  - Dickhuth, Hans-Hermann
A1  - Suedkamp, Norbert P.
A1  - Helwig, Peter
T1  - Prognostic value of achilles tendon doppler sonography in asymptomatic runners
JF  - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine
N2  - HIRSCHMULLER, A., V. FREY, L. KONSTANTINIDIS, H. BAUR, H-H. DICKHUTH, N. P. SUDKAMP, and P. HELWIG. Prognostic Value of Achilles Tendon Doppler Sonography in Asymptomatic Runners. Med. Sci. Sports Exerc., Vol. 44, No. 2, pp. 199-205, 2012. Introduction: Midportion Achilles tendinopathy (MPT) is a common problem in running athletes. Nevertheless, its etiology is not fully understood, and no valid prognostic criterion to predict the development of MPT could be identified to date. The purpose of the present study, therefore, was to evaluate whether power Doppler ultrasonography (PDU) is a suitable method to identify a predisposition to MPT in yet asymptomatic runners. Methods: At 23 major running events, 634 asymptomatic long-distance runners were tested for Achilles tendon thickness, vascularization, and structural abnormalities using a high-resolution PDU device (Toshiba Aplio SSA-770A/80, 12 MHz). In addition, their medical history and anthropometric data were documented. All subjects were contacted 6 and 12 months later and asked about any new symptoms. The collected anamnestic, anthropometric, and ultrasonographic data were subjected to regression analysis to determine their predictive value concerning the manifestation of midportion Achilles tendon complaints (P < 0.05). Results: The highest odds ratio (OR) for manifestation of MPT within 1 yr was found for intratendinous blood flow ("neovascularization,'' OR = 6.9, P < 0.001). An increased risk was also identified for subjects with a positive history of Achilles tendon complaints (OR = 3.8, P < 0.001). A third relevant parameter, just above the level of significance, was a spindle-shaped thickening of the tendon on PDU (Wald chi(2) = 3.42). Conclusions: PDU detection of intratendinous microvessels in the Achilles tendons of healthy runners seems to be a prognostically relevant factor concerning the manifestation of symptomatic MPT. This finding lays the foundation for an early identification of a predisposition to MPT as well as prophylactic intervention in as yet asymptomatic runners.
KW  - MIDPORTION
KW  - TENDINOPATHY
KW  - NEOVASCULARIZATION
KW  - PROGNOSIS
Y1  - 2012
U6  - https://doi.org/10.1249/MSS.0b013e31822b7318
SN  - 0195-9131
VL  - 44
IS  - 2
SP  - 199
EP  - 205
PB  - Lippincott Williams & Wilkins
CY  - Philadelphia
ER  - 
TY  - GEN
A1  - Hirschmueller, Anja
A1  - Baur, Heiner
A1  - Braun, Sepp
A1  - Kreuz, Peter C.
A1  - Suedkamp, Norbert P
A1  - Niemeyer, Philipp
T1  - Rehabilitation after autologous chondrocyte implantation for isolated cartilage defects of the knee
N2  - Autologous chondrocyte implantation for treatment of isolated cartilage defects of the knee has become well established. Although various publications report technical modifications, clinical results, and cell-related issues, little is known about appropriate and optimal rehabilitation after autologous chondrocyte implantation. This article reviews the literature on rehabilitation after autologous chondrocyte implantation and presents a rehabilitation protocol that has been developed considering the best available evidence and has been successfully used for several years in a large number of patients who underwent autologous chondrocyte implantation for cartilage defects of the knee.
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 367 
KW  - autologous chondrocyte implantation
KW  - cartilage repair
KW  - cartilage defect
KW  - cell transplantation
KW  - knee joint
KW  - rehabilitation
Y1  - 2017
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-403170
ER  -