TY  - JOUR
A1  - Okano, J.
A1  - Shiota, G.
A1  - Matsumoto, K.
A1  - Yasui, S.
A1  - Kurimasa, A.
A1  - Hisatome, I.
A1  - Steinberg, Pablo
A1  - Murawaki, Y.
T1  - Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Bartsch, Ingrid
A1  - Zschaler, Ingrid
A1  - Haseloff, Monika
A1  - Steinberg, Pablo
T1  - Establishment of a long-term culture system for rat colon epithelial cells
N2  - The aim of this study was to establish a long-term culture. system for rat colon epithelia isolaled by incubating a 4-cm-long rat colon segment cut longitudinally with all ethylenediaminetetraacetic acid [disodium salt]- containing buffer, taken up in conditioned medium from the normal rat kidney fibroblast cell line NRK (i.e., the supernatant Of pure NRK cultures), directly plated on mitomycin C-treated NRK cells and subcultured with conditioned medium from NRK cells. Cells started to migrate out of the crypts shortly after plating them on NRK feeder layers. Some of the crypts fell apart during the isolation procedure. whereas the vast majority of them did it within I to 2 Ill after plating. The cells proliferated extremely slowly but continuously over a period of 4 mo and were epithelial because they expressed cytokeratin 19 and were stained by crystal violet at pH 2.8. In conclusion, the experimental system described ill this study allows to maintain rat colon epithelial cells for up to 4 mo in culture and can be used to Study the effects of a variety of tumor-modulating factors on growth and gene expression of normal colon epithelial cells in vitro
Y1  - 2003
UR  - http://www.springerlink.com/content/120498/
U6  - https://doi.org/10.1290/0404035.1
SN  - 1071-2690
ER  - 
TY  - JOUR
A1  - Barlow, S. M.
A1  - Greig, J. B.
A1  - Bridges, J. W.
A1  - Carere, A.
A1  - Carpy, A. J.
A1  - Galli, Corrado L.
A1  - Kleiner, J.
A1  - Knudsen, I.
A1  - Koeter, H. B.
A1  - Levy, L. S.
A1  - Madsen, C.
A1  - Mayer, S.
A1  - Narbonne, J. F.
A1  - Pfannkuch, F.
A1  - Prodanchuk, M. G.
A1  - Smith, Mason R.
A1  - Steinberg, Pablo
T1  - Hazard identification by methods of animal-based toxicology
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Dybing, E.
A1  - Doe, J.
A1  - Groten, J.
A1  - Kleiner, J.
A1  - O'Brien, J.
A1  - Renwick, A. G.
A1  - Schlatter, J.
A1  - Steinberg, Pablo
A1  - Tritschler, A.
A1  - Walker, R.
A1  - Younes, M.
T1  - Hazard characterisation of chemicals in food and diet : dose response, mechanisms and extrapolation issues
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Volohonsky, Gloria
A1  - Tuby, Chen N. Y. H.
A1  - Porat, Noga
A1  - Wellman-Rousseau, Maria
A1  - Visvikis, Athanase
A1  - Leroy, Pierre
A1  - Rashi, Sharon
A1  - Steinberg, Pablo
A1  - Stark, Avishay Abraham
T1  - A spectrophotometric assay of gamma-glutamylcysteine synthetase and glutathione synthetase in crude extracts from tissues and cultured mammalian cells
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Steinberg, Pablo
A1  - Zschaler, Ingrid
A1  - Thom, Elke
A1  - Kuna, Manuela
A1  - Wüst, Günter
A1  - Schäfer-Schwebel, Angelika
A1  - Müller, Rolf
A1  - Kramer, Peter-Jürgen
A1  - Weiße, Günter
T1  - The polycyclic musk 7-acetyl-1,1,3,4,4,6-hexamethyl-1,2,3,4-tetrahydronaphthaline lacks liver tumor initiating and promoting activity in rats exposed to human-relevant doses
Y1  - 2001
UR  - http://www.springerlink.com/content/100462
U6  - https://doi.org/10.1007/s002040100274
SN  - 0340-5761
ER  - 
TY  - JOUR
A1  - Komlosh, A.
A1  - Volohonsky, Gloria
A1  - Porat, Noga
A1  - Tuby, chen n. y. h.
A1  - Bluvshtein, Evgenia
A1  - Steinberg, Pablo
A1  - Oesch, Franz
A1  - Stark, Avishay Abraham
T1  - Gamma-glutamyl transpeptidase and glutathione biosynthesis in non-tumorigenic and tumorigenic rat liver oval cell lines
Y1  - 2001
ER  - 
TY  - JOUR
A1  - Hengstler, Jan Georg
A1  - Utesch, D.
A1  - Steinberg, Pablo
T1  - Cryopreserved primary hepatocytes as a constantly available in vitro model for the evaluation of human and animal drug metabolism and enzyme induction
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Schleger, C.
A1  - Heck, R.
A1  - Steinberg, Pablo
T1  - The role of wild-type and mutated N-ras in the malignant transformation of liver cells
Y1  - 2000
ER  - 
TY  - JOUR
A1  - Hengstler, Jan Georg
A1  - Ringel, M.
A1  - Biefang, Katja
A1  - Hammel, S.
A1  - Milbert, U.
A1  - Gerl, M.
A1  - Klebach, M.
A1  - Diener, B.
A1  - Platt, Karl-Ludwig
A1  - Böttger, Thomas
A1  - Steinberg, Pablo
A1  - Oesch, Franz
T1  - Cultures with cryopreserved hepatocytes : applicability for studies of enzyme induction
Y1  - 2000
ER  -