TY  - JOUR
A1  - Singh, Jasbir
A1  - Singh, S.
A1  - Dani, H. M.
A1  - Sharma, Reeta
A1  - Steinberg, Pablo
T1  - Interactions of aflatoxin B-1 with SRP components can disrupt protein targeting
N2  - Spectrofluorimetric studies have revealed that aflatoxin B-1 (AFB(1)) interacts with signal recognition particle (SRP), which acts as an escort for polyribosomes with signal peptides to be transported and bound to the cytoplasmic face of the endoplasmic reticulum (ER). We further report that the binding of AFB(1) to SRP is selective as it only binds to two (SRP9 and 14) out of its three constituent polypeptides studied. Binding of AFB(1) to proteins is known to alter their conformations. Interactions of AFB(1) with SRP polypeptides may generate structural and functional alterations in this particle and hinder secretory protein synthesis. Copyright (C) 2004 John Wiley Sons, Ltd
Y1  - 2005
SN  - 0263-6484
ER  - 
TY  - JOUR
A1  - Fuchs, J.
A1  - Teubner, Wera
A1  - Steinberg, Pablo
T1  - The resistance of intestinal epithelial cells towards the transforming activity of 2-hydroxyamino-1-methyl-6- phenylimidazo[4,5-B]pyridine is accompanied by glutathione S-transferase induction
Y1  - 2004
SN  - 0028-1298
ER  - 
TY  - JOUR
A1  - Teubner, Wera
A1  - Langheinrich, C.
A1  - Seidel, Albrecht
A1  - Steinberg, Pablo
T1  - Inhibition of p53 transactivation activity does not promote mutagen-induced transformation of IEC-18
Y1  - 2004
SN  - 0028-1298
ER  - 
TY  - JOUR
A1  - Stark, Avishay abraham
A1  - Porat, Noga
A1  - Volohonsky, Gloria
A1  - Konlosh, A.
A1  - Bluvshtein, Evgenia
A1  - Tubi, C.
A1  - Steinberg, Pablo
T1  - The role of gamma-glutamyl transpeptidase in the biosynthesis of glutathione
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Okano, J.
A1  - Shiota, G.
A1  - Matsumoto, K.
A1  - Yasui, S.
A1  - Kurimasa, A.
A1  - Hisatome, I.
A1  - Steinberg, Pablo
A1  - Murawaki, Y.
T1  - Hepatocyte growth factor exerts a proliferative effect on oval cells through the PI3K/AKT signaling pathway
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Bartsch, Ingrid
A1  - Zschaler, Ingrid
A1  - Haseloff, Monika
A1  - Steinberg, Pablo
T1  - Establishment of a long-term culture system for rat colon epithelial cells
N2  - The aim of this study was to establish a long-term culture. system for rat colon epithelia isolaled by incubating a 4-cm-long rat colon segment cut longitudinally with all ethylenediaminetetraacetic acid [disodium salt]- containing buffer, taken up in conditioned medium from the normal rat kidney fibroblast cell line NRK (i.e., the supernatant Of pure NRK cultures), directly plated on mitomycin C-treated NRK cells and subcultured with conditioned medium from NRK cells. Cells started to migrate out of the crypts shortly after plating them on NRK feeder layers. Some of the crypts fell apart during the isolation procedure. whereas the vast majority of them did it within I to 2 Ill after plating. The cells proliferated extremely slowly but continuously over a period of 4 mo and were epithelial because they expressed cytokeratin 19 and were stained by crystal violet at pH 2.8. In conclusion, the experimental system described ill this study allows to maintain rat colon epithelial cells for up to 4 mo in culture and can be used to Study the effects of a variety of tumor-modulating factors on growth and gene expression of normal colon epithelial cells in vitro
Y1  - 2003
UR  - http://www.springerlink.com/content/120498/
U6  - https://doi.org/10.1290/0404035.1
SN  - 1071-2690
ER  - 
TY  - JOUR
A1  - Barlow, S. M.
A1  - Greig, J. B.
A1  - Bridges, J. W.
A1  - Carere, A.
A1  - Carpy, A. J.
A1  - Galli, Corrado L.
A1  - Kleiner, J.
A1  - Knudsen, I.
A1  - Koeter, H. B.
A1  - Levy, L. S.
A1  - Madsen, C.
A1  - Mayer, S.
A1  - Narbonne, J. F.
A1  - Pfannkuch, F.
A1  - Prodanchuk, M. G.
A1  - Smith, Mason R.
A1  - Steinberg, Pablo
T1  - Hazard identification by methods of animal-based toxicology
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Dybing, E.
A1  - Doe, J.
A1  - Groten, J.
A1  - Kleiner, J.
A1  - O'Brien, J.
A1  - Renwick, A. G.
A1  - Schlatter, J.
A1  - Steinberg, Pablo
A1  - Tritschler, A.
A1  - Walker, R.
A1  - Younes, M.
T1  - Hazard characterisation of chemicals in food and diet : dose response, mechanisms and extrapolation issues
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Volohonsky, Gloria
A1  - Tuby, Chen N. Y. H.
A1  - Porat, Noga
A1  - Wellman-Rousseau, Maria
A1  - Visvikis, Athanase
A1  - Leroy, Pierre
A1  - Rashi, Sharon
A1  - Steinberg, Pablo
A1  - Stark, Avishay Abraham
T1  - A spectrophotometric assay of gamma-glutamylcysteine synthetase and glutathione synthetase in crude extracts from tissues and cultured mammalian cells
Y1  - 2002
ER  - 
TY  - GEN
A1  - Steinberg, Pablo
T1  - Only one Component of a holistic Nutrition Policy
T1  - Nur ein Baustein einer ganzheitlichen Ernährungspolitik
T2  - Fleischwirtschaft
Y1  - 2018
SN  - 0015-363X
VL  - 98
IS  - 11
SP  - 8
EP  - 9
PB  - Deutscher Fachverlag GmbH
CY  - Frankfurt am Main
ER  -