TY - JOUR A1 - Sarauli, David A1 - Xu, Chenggang A1 - Dietzel, Birgit A1 - Schulz, Burkhard A1 - Lisdat, Fred T1 - Differently substituted sulfonated polyanilines - the role of polymer compositions in electron transfer with pyrroloquinoline quinone-dependent glucose dehydrogenase JF - Acta biomaterialia N2 - Sulfonated polyanilines have become promising building blocks in the construction of biosensors, and therefore we use here differently substituted polymer forms to investigate the role of their structural composition and properties in achieving a direct electron transfer with the redox enzyme pyrroloquinoline quinone-dependent glucose dehydrogenase (PQQ-GDH). To this end, new copolymers containing different ratios of 2-methoxyaniline-5-sulfonic acid (MAS), 3-aminobenzenesulfonic acid (ABS) and 3-aminobenzoic acid (AB) units have been chemically synthesized. All polymers have been studied with respect to their ability to react directly with PQQ-GDH. This interaction has been monitored initially in solution, and subsequently on electrode surfaces. The results show that only copolymers with MAS and aniline units can directly react with PQQ-GDH in solution; the background can be mainly ascribed to the emeraldine salt redox state of the polymer, allowing rather easy reduction. However, when polymers and the enzyme are immobilized on the surface of carbon nanotube-containing electrodes, direct bioelectrocatalysis is also feasible in the case of copolymers composed of ABS/AB and MAS/AB units, existing initially in pernigraniline base form. This verifies that a productive interaction of the enzyme with differently substituted polymers is feasible when the electrode potential can be used to drive the reaction towards the oxidation of the substrate-reduced enzyme. These results clearly demonstrate that enzyme electrodes based on sulfonated polyanilines and direct bioelectrocatalysis can be successfully constructed. KW - Sulfonated polyaniline KW - PQQ-dependent glucose dehydrogenase KW - Direct electron transfer KW - Immobilization KW - Bioelectrocatalysis Y1 - 2013 U6 - https://doi.org/10.1016/j.actbio.2013.06.008 SN - 1742-7061 VL - 9 IS - 9 SP - 8290 EP - 8298 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Bruma, Maria A1 - Schulz, Burkhard A1 - Mercer, Frank W. T1 - Polyamide copolymers containing hexafluoroisopropylidene groups Y1 - 1995 ER - TY - JOUR A1 - Schulz, Burkhard A1 - Stiller, Burkhard A1 - Zetzsche, Thomas A1 - Knochenhauer, Gerald A1 - Dietel, Reinhard A1 - Brehmer, Ludwig T1 - Crystal structure of 2,5-Di(4- methoxycarbonyl-phenyl)-1,3,4-oxadiazole characterized by AFM and IR- spectroscopy Y1 - 1994 ER - TY - JOUR A1 - Mercer, Frank W. A1 - McKenzie, M. A1 - Bruma, Maria A1 - Schulz, Burkhard T1 - Synthesis and properties of fluorinated polyimides and fluorinated poly(imide-amide)s containing pendent cyano groups Y1 - 1994 ER - TY - JOUR A1 - Schulz, Burkhard A1 - Knochenhauer, Gerald A1 - Brehmer, Ludwig A1 - Janietz, Silvia T1 - Stuctures and properties of aromatic poly(1,3,4-oxadiazole)s Y1 - 1994 ER - TY - JOUR A1 - Bruma, Maria A1 - Mercer, Frank W. A1 - Schulz, Burkhard A1 - Dietel, Reinhard A1 - Fitch, J. A1 - Cassidy, Peter T1 - Study of crosslinking process in fluorinated poly(imide-amide)s containing pendant cyano groups Y1 - 1994 ER - TY - JOUR A1 - Bruma, Maria A1 - Mercer, Frank W. A1 - Schulz, Burkhard A1 - Dietel, Reinhard A1 - Fitch, J. A1 - Cassidy, Peter T1 - Study of crosslinking process in fluorinated poly(imide-amide)s containing pendant cyano groups Y1 - 1994 ER - TY - JOUR A1 - Bruma, Maria A1 - Mercer, Frank W. A1 - Schulz, Burkhard A1 - Dietel, Reinhard A1 - Neumann, Werner T1 - Fluorinated poly(benzoxazole-imide)s Y1 - 1994 ER - TY - JOUR A1 - Bruma, Maria A1 - Schulz, Burkhard A1 - Mercer, Frank W. T1 - Synthesis and characterization of fluorinated poly(imide-pyridazine- amide)s Y1 - 1994 ER - TY - JOUR A1 - Janietz, Silvia A1 - Schulz, Burkhard T1 - Electrochemical studies on thin films of poly(arylene-1,3,4-oxadiazole)s Y1 - 1994 ER -