TY - JOUR A1 - Rohner, Fabian A1 - Frey, Simone K. A1 - Mothes, Ralf A1 - Hurtienne, Andrea A1 - Hartong, Simone A1 - Bosso, Patrice Emery A1 - Bui, Mai A1 - Schweigert, Florian J. A1 - Northrop-Clewes, Christine T1 - Quantification of vitamin A in palm oil using a fast and simple portable device method validation and comparison to high-performance liquid chromatography JF - International journal for vitamin and nutrition research N2 - Vitamin A deficiency continues to be a global public health problem. Fortification of oil with vitamin A is considered a cost-effective, feasible strategy to prevent this problem but quality control poses a challenge to program implementation. To overcome this, we have validated a newly developed device that quantitatively measures the content of retinyl palmitate in refined palm oil, is simple to use, and yields immediate results. Linearity of analysis rand from 2.5-30 mg retinol equivalents (RE)/kg of palm oil, with 2.5 mg RE/kg being the determination limit; inter- and intra-assay precision ranged from 1.4-7.1 To. Comparison with a high-performance Liquid chromatography method showed high agreement between the methods (R-2 = 0.92; Limits of Agreement: -1.24 mg to 2.53 mg RE/kg), and further comparisons illustrate that the new device is useful in low resource settings. This device offers a field- and user-friendly solution to quantifying the vitamin A content in refined palm oil. KW - Vitamin A KW - retinyl palmitate KW - fortification KW - monitoring KW - rapid test kit KW - palm oil Y1 - 2011 U6 - https://doi.org/10.1024/0300-9831/a000081 SN - 0300-9831 VL - 81 IS - 5 SP - 335 EP - 342 PB - Hogrefe CY - Bern ER - TY - JOUR A1 - Rohner, Fabian A1 - Garrett, Greg S. A1 - Laillou, Arnaud A1 - Frey, Simone K. A1 - Mothes, Ralf A1 - Schweigert, Florian J. A1 - Locatelli-Rossi, Lorenzo T1 - Validation of a user-friendly and rapid method for quantifying iodine content of salt JF - Food and nutrition bulletin N2 - Background. Despite considerable progress made in the past decade through salt iodization programs, over 2 billion people worldwide still have inadequate iodine intake, with devastating consequences for brain development and intellectual capacity. To optimize these programs with regard to salt iodine content, careful monitoring of salt iodine content is essential, but few methods are available to quantitatively measure iodine concentration in a simple, fast, and safe way. Objective. We have validated a newly developed device that quantitatively measures the content of potassium iodate in salt in a simple, safe, and rapid way. Methods. The linearity, determination and detection limit, and inter- and intra-assay variability of this colorimetric method were assessed and the method was compared with iodometric titration, using salt samples from several countries. Results. Linearity of analysis ranged from 5 to 75 mg/kg iodine, with I mg/kg being the determination limit; the intra- and interassay imprecision was 0.9%, 0.5%, and 0.7% and 1.5%, 1.7%, and 2.5% for salt samples with iodine contents of 17, 30, and 55 mg/kg, respectively; the interoperator imprecision for the same samples was 1.2%, 4.9%, and 4.7%, respectively. Comparison with the iodometric method showed high agreement between the methods (R-2 = 0.978; limits of agreement, -10.5 to 10.0 mg/kg). Conclusions. The device offers a field- and user-friendly solution to quantifying potassium iodate salt content reliably. For countries that use potassium iodide in salt iodization programs, further validation is required. KW - Iodization KW - iodine KW - monitoring KW - potassium iodate KW - quality control KW - rapid test kit KW - regulatory monitoring KW - salt Y1 - 2012 SN - 0379-5721 VL - 33 IS - 4 SP - S330 EP - S335 PB - International Nutrition Foundation CY - Boston ER -