TY  - JOUR
A1  - Schöne, Anne-Christin
A1  - Roch, Toralf
A1  - Schulz, Burkhard
A1  - Lendlein, Andreas
T1  - Evaluating polymeric biomaterial-environment interfaces by Langmuir monolayer techniques
JF  - Interface : journal of the Royal Society
N2  - Polymeric biomaterials are of specific relevance in medical and pharmaceutical applications due to their wide range of tailorable properties and functionalities. The knowledge about interactions of biomaterials with their biological environment is of crucial importance for developing highly sophisticated medical devices. To achieve optimal in vivo performance, a description at the molecular level is required to gain better understanding about the surface of synthetic materials for tailoring their properties. This is still challenging and requires the comprehensive characterization of morphological structures, polymer chain arrangements and degradation behaviour. The review discusses selected aspects for evaluating polymeric biomaterial-environment interfaces by Langmuir monolayer methods as powerful techniques for studying interfacial properties, such as morphological and degradation processes. The combination of spectroscopic, microscopic and scattering methods with the Langmuir techniques adapted to polymers can substantially improve the understanding of their in vivo behaviour.
KW  - Langmuir monolayer
KW  - biodegradable polymers
KW  - air - water interface
KW  - protein Langmuir layers
Y1  - 2017
U6  - https://doi.org/10.1098/rsif.2016.1028
SN  - 1742-5689
SN  - 1742-5662
VL  - 14
PB  - Royal Society
CY  - London
ER  -