TY  - THES
A1  - Möllnitz, Kristian
T1  - Synthese und Untersuchung von molekularen Stäben basierend auf Oligospiroketalen
Y1  - 2012
CY  - Potsdam
ER  - 
TY  - JOUR
A1  - Wessig, Pablo
A1  - Möllnitz, Kristian
T1  - Building blocks for oligospiroketal (OSK) rods and evaluation of their influence on rod rigidity
JF  - The journal of organic chemistry
N2  - We report on the synthesis of three new sleeves and their incorporation in OSK rods. The structures of these sleeves are based on neo-inositol, terephthalaldehyde diacetals, and indacene. To quantify the influence of the sleeves on rod rigidity, we applied the worm-like chain (WLC) model on the new rods and found that this approach is rather disappointing. As the chief cause of this result, we assume that the rigidity of typical molecular rods largely exceeds the rigidity of polymers, which were successfully described by the WLC model. Alternatively, we suggest quantifying the rigidity of molecular rods by fitting an empirical function on the end-to-end distance distribution curve obtained by MD simulations. After checking various function types, the Levy-Martin function proved to be most suitable for this purpose. On the basis of this function, we defined the Levy-Martin parameter and suggest using this parameter for the characterization of the rigidity of molecular rods.
Y1  - 2012
U6  - https://doi.org/10.1021/jo300266b
SN  - 0022-3263
VL  - 77
IS  - 8
SP  - 3907
EP  - 3920
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Wawrzinek, Robert
A1  - Wessig, Pablo
A1  - Möllnitz, Kristian
A1  - Nikolaus, Joerg
A1  - Schwarzer, Roland
A1  - Müller, Peter
A1  - Herrmann, Andreas
T1  - DBD dyes as fluorescent probes for sensing lipophilic environments
JF  - Bioorganic & medicinal chemistry letters : a Tetrahedron publication for rapid dissemination of preliminary communications on all aspects of bioorganic chemistry, medicinal chemistry and related disciplines
N2  - Small fluorescent organic molecules based on [1,3]dioxolo[4,5-f][1,3]benzodioxole (DBD) could be used as probes for lipophillic microenvironments in aqueous solutions by indicating the critical micelles concentration of detergents and staining cell organelles. Their fluorescence lifetime decreases drastically by the amount of water in their direct environment. Therefore they are potential probes for fluorescence lifetime imaging microscopy (FLIM).
KW  - Fluorescence lifetime probes
KW  - FLIM
KW  - Cell staining
KW  - Lysotrackers
KW  - Detergents
Y1  - 2012
U6  - https://doi.org/10.1016/j.bmcl.2012.07.056
SN  - 0960-894X
VL  - 22
IS  - 17
SP  - 5367
EP  - 5371
PB  - Elsevier
CY  - Oxford
ER  -