TY - JOUR A1 - Schmidt, G. A1 - Zamora-Lopez, Gorka A1 - Kurths, Jürgen T1 - Simulation of large scale cortical networks by individual neuron dynamics N2 - Understanding the functional dynamics of the mammalian brain is one of the central aims of modern neuroscience. Mathematical modeling and computational simulations of neural networks can help in this quest. In recent publications, a multilevel model has been presented to simulate the resting-state dynamics of the cortico-cortical connectivity of the mammalian brain. In the present work we investigate how much of the dynamical behavior of the multilevel model can be reproduced by a strongly simplified model. We find that replacing each cortical area by a single Rulkov map recreates the patterns of dynamical correlation of the multilevel model, while the outcome of other models and setups mainly depends on the local network properties, e. g. the input degree of each vertex. In general, we find that a simple simulation whose dynamics depends on the global topology of the whole network is far from trivial. A systematic analysis of different dynamical models and coupling setups is required. Y1 - 2010 U6 - https://doi.org/10.1142/S0218127410026149 SN - 0218-1274 ER -