TY - JOUR A1 - Orgis, Thomas A1 - Brand, Sascha A1 - Schwarz, Udo A1 - Handorf, Dörthe A1 - Dethloff, Klaus A1 - Kurths, Jürgen T1 - Influence of interactive stratospheric chemistry on large-scale air mass exchange in a global circulation model N2 - A new globally uniform Lagrangian transport scheme for large ensembles of passive tracer particles is presented and applied to wind data from a coupled atmosphere-ocean climate model that includes interactive dynamical feedback with stratospheric chemistry. This feedback from the chemistry is found to enhance large-scale meridional air mass exchange in the northern winter stratosphere as well as intrusion of stratospheric air into the troposphere, where both effects are due to a weakened polar vortex. Y1 - 2009 UR - http://www.springerlink.com/content/1951-6355 U6 - https://doi.org/10.1140/epjst/e2009-01105-8 SN - 1951-6355 ER - TY - GEN A1 - Koseska, Aneta A1 - Zaikin, Alexey A1 - Kurths, Jürgen A1 - García-Ojalvo, Jordi T1 - Timing cellular decision making under noise via cell-cell communication N2 - Many cellular processes require decision making mechanisms, which must act reliably even in the unavoidable presence of substantial amounts of noise. However, the multistable genetic switches that underlie most decision-making processes are dominated by fluctuations that can induce random jumps between alternative cellular states. Here we show, via theoretical modeling of a population of noise-driven bistable genetic switches, that reliable timing of decision-making processes can be accomplished for large enough population sizes, as long as cells are globally coupled by chemical means. In the light of these results, we conjecture that cell proliferation, in the presence of cell-cell communication, could provide a mechanism for reliable decision making in the presence of noise, by triggering cellular transitions only when the whole cell population reaches a certain size. In other words , the summation performed by the cell population would average out the noise and reduce its detrimental impact. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 148 Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-45260 ER - TY - JOUR A1 - Komalapriya, Chandrasekaran A1 - Romano Blasco, Maria Carmen A1 - Thiel, Marco A1 - Schwarz, Udo A1 - Kurths, Jürgen A1 - Simonotto, Jennifer A1 - Furman, Michael A1 - Ditto, William L. A1 - Carney, Paul R. T1 - Analysis of high-resulution microelectrode EEG recordings in an animal model of spontaneous limbic seizures Y1 - 2009 UR - http://www.worldscinet.com/ijbc/ijbc.shtml U6 - https://doi.org/10.1142/S0218127409023226 SN - 0218-1274 ER - TY - JOUR A1 - Li, Ping A1 - Chen, Maoyin A1 - Wu, Ye A1 - Kurths, Jürgen T1 - Matrix-measure criterion for synchronization in coupled-map networks N2 - We present conditions for the local and global synchronizations in coupled-map networks using the matrix measure approach. In contrast to many existing synchronization conditions, the proposed synchronization criteria do not depend on the solution of the synchronous state and give less limitation on the network connections. Numerical simulations of the coupled quadratic maps demonstrate the potentials of our main results. Y1 - 2009 UR - http://pre.aps.org/ U6 - https://doi.org/10.1103/Physreve.79.067102 SN - 1539-3755 ER - TY - JOUR A1 - Florence, Gerson A1 - Dahlem, Markus A. A1 - Almeida, Antônio-Carlos G. A1 - Bassani, José W. M. A1 - Kurths, Jürgen T1 - The role of extracellular potassium dynamics in the different stages of ictal bursting and spreading depression : a computational study N2 - Experimental evidences point Out the participation of nonsynaptic mechanisms (e.g., fluctuations in extracellular tons) in epileptiform bursting and spreading depression (SD). During these abnormal oscillatory patterns, it is observed an increase of extracellular potassium concentration [K+](o) and a decrease of extracellular calcium concentration [Ca2+](o) which raises the neuronal excitability. However, whether the high [K+](o) triggers and propagates these abnormal neuronal activities or plays a secondary role into this process is unclear. To better understand the influence of extracellular potassium dynamics in these oscillatory patterns, the experimental conditions of high [K+](o) and zero [Ca2+](o) were replicated in an extended Golomb model where we added important regulatory mechanisms of ion concentration as Na+-K+ pump, ion diffusion and glial buffering. Within these Conditions, simulations of the cell model exhibit seizure-like discharges (ictal bursting). The SD was elicited by the interruption of the Na+- K+ pump activity, mimicking the effect of cellular hypoxia (an experimental protocol to elicit SD, the hypoxia-induced SD). We used the bifurcation theory and the fast-slow method to analyze the interference of K+ dynamics in the cellular excitability. This analysis indicates that the system loses its stability at a high [K+](o), transiting to an elevated state of neuronal excitability. Effects of high [K+](o), are observed in different stages of ictal bursting and SD. In the initial stage, the increase of [K+](o) creates favorable conditions to trigger both oscillatory patterns. During the neuronal activity, a continuous growth of [K+](o) by outward K+ flow depresses K+ Currents in a positive feedback way. At the last stage, due to the depression of K+ currents, the Na+-K+ pump is the main mechanism in the end of neuronal activity. Thus, this work suggests that [K+](o) dynamics may play a fundamental role in these abnormal oscillatory patterns. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00225193 U6 - https://doi.org/10.1016/j.jtbi.2009.01.032 SN - 0022-5193 ER - TY - JOUR A1 - Wessel, Niels A1 - Riedl, Maik A1 - Kurths, Jürgen T1 - Is the normal heart rate "chaotic" due to respiration? N2 - The incidence of cardiovascular diseases increases with the growth of the human population and an aging society, leading to very high expenses in the public health system. Therefore, it is challenging to develop sophisticated methods in order to improve medical diagnostics. The question whether the normal heart rate is chaotic or not is an attempt to elucidate the underlying mechanisms of cardiovascular dynamics and therefore a highly controversial topical challenge. In this contribution we demonstrate that linear and nonlinear parameters allow us to separate completely the data sets of the three groups provided for this controversial topic in nonlinear dynamics. The question whether these time series are chaotic or not cannot be answered satisfactorily without investigating the underlying mechanisms leading to them. We give an example of the dominant influence of respiration on heart beat dynamics, which shows that observed fluctuations can be mostly explained by respiratory modulations of heart rate and blood pressure (coefficient of determination: 96%). Therefore, we recommend reformulating the following initial question: "Is the normal heart rate chaotic?" We rather ask the following: " Is the normal heart rate 'chaotic' due to respiration?" Y1 - 2009 UR - http://ojps.aip.org/chaos/ U6 - https://doi.org/10.1063/1.3133128 SN - 1054-1500 ER - TY - JOUR A1 - Wu, Ye A1 - Li, Ping A1 - Chen, Maoyin A1 - Xiao, Jinghua A1 - Kurths, Jürgen T1 - Response of scale-free networks with community structure to external stimuli N2 - The response of scale-free networks with community structure to external stimuli is studied. By disturbing some nodes with different strategies, it is shown that the robustness of this kind of network can be enhanced due to the existence of communities in the networks. Some of the response patterns are found to coincide with topological communities. We show that such phenomena also occur in the cat brain network which is an example of a scale-free like network with community structure. Our results provide insights into the relationship between network topology and the functional organization in complex networks from another viewpoint. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/03784371 U6 - https://doi.org/10.1016/j.physa.2009.03.037 SN - 0378-4371 ER - TY - JOUR A1 - Sun, Xiaojuan A1 - Lu, Qishao A1 - Kurths, Jürgen A1 - Wang, Qingyun T1 - Spatiotemporal coherence resonance in a map lattice N2 - We study the effects of parametric noise on a lattice network, which is locally modeled by a two-dimensional Rulkov map. We conclude that at some intermediate noise intensity, parametric noise can induce ordered circular patterns, which indicates the appearance of spatiotemporal coherence resonance in the studied lattice. With the observation of coherence-like manner in linear spatial cross-correlation, the coherence phenomena can be analyzed quantitatively. Y1 - 2009 UR - http://www.worldscinet.com/ijbc/ijbc.shtml U6 - https://doi.org/10.1142/S021812740902310X SN - 0218-1274 ER - TY - JOUR A1 - Fujiwara, Naoya A1 - Kurths, Jürgen T1 - Spectral universality of phase synchronization in non-identical oscillator networks N2 - We employ a spectral decomposition method to analyze synchronization of a non-identical oscillator network. We study the case that a small parameter mismatch of oscillators is characterized by one parameter and phase synchronization is observed. We derive a linearized equation for each eigenmode of the coupling matrix. The parameter mismatch is reflected on inhomogeneous term in the linearized equation. We find that the oscillation of each mode is essentially characterized only by the eigenvalue of the coupling matrix with a suitable normalization. We refer to this property as spectral universality, because it is observed irrespective of network topology. Numerical results in various network topologies show good agreement with those based on linearized equation. This universality is also observed in a system driven by additive independent Gaussian noise. Y1 - 2009 UR - http://www.springerlink.com/content/101159 U6 - https://doi.org/10.1140/epjb/e2009-00078-6 SN - 1434-6028 ER - TY - JOUR A1 - Koseska, Aneta A1 - Volkov, Evgenij A1 - Kurths, Jürgen T1 - Detuning-dependent dominance of oscillation death in globally coupled synthetic genetic oscillators N2 - We study dynamical regimes of globally coupled genetic relaxation oscillators in the presence of small detuning. Using bifurcation analysis, we find that under strong coupling via the slow variable, the detuning can eliminate standard oscillatory solutions in a large region of the parameter space, providing the dominance of oscillation death. This result is substantially different from previous results on oscillation quenching, where for homogeneous populations, the coexistence of oscillation death and limit cycle oscillations is always present. We propose further that this effect of detuning-dependent dominance could be a powerful regulator of genetic network's dynamics. Y1 - 2009 UR - http://iopscience.iop.org/0295-5075/ U6 - https://doi.org/10.1209/0295-5075/85/28002 SN - 0295-5075 ER -