TY - JOUR A1 - Orgis, Thomas A1 - Brand, Sascha A1 - Schwarz, Udo A1 - Handorf, Dörthe A1 - Dethloff, Klaus A1 - Kurths, Jürgen T1 - Influence of interactive stratospheric chemistry on large-scale air mass exchange in a global circulation model N2 - A new globally uniform Lagrangian transport scheme for large ensembles of passive tracer particles is presented and applied to wind data from a coupled atmosphere-ocean climate model that includes interactive dynamical feedback with stratospheric chemistry. This feedback from the chemistry is found to enhance large-scale meridional air mass exchange in the northern winter stratosphere as well as intrusion of stratospheric air into the troposphere, where both effects are due to a weakened polar vortex. Y1 - 2009 UR - http://www.springerlink.com/content/1951-6355 U6 - https://doi.org/10.1140/epjst/e2009-01105-8 SN - 1951-6355 ER - TY - GEN A1 - Koseska, Aneta A1 - Zaikin, Alexey A1 - Kurths, Jürgen A1 - García-Ojalvo, Jordi T1 - Timing cellular decision making under noise via cell-cell communication N2 - Many cellular processes require decision making mechanisms, which must act reliably even in the unavoidable presence of substantial amounts of noise. However, the multistable genetic switches that underlie most decision-making processes are dominated by fluctuations that can induce random jumps between alternative cellular states. Here we show, via theoretical modeling of a population of noise-driven bistable genetic switches, that reliable timing of decision-making processes can be accomplished for large enough population sizes, as long as cells are globally coupled by chemical means. In the light of these results, we conjecture that cell proliferation, in the presence of cell-cell communication, could provide a mechanism for reliable decision making in the presence of noise, by triggering cellular transitions only when the whole cell population reaches a certain size. In other words , the summation performed by the cell population would average out the noise and reduce its detrimental impact. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 148 Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-45260 ER - TY - JOUR A1 - Komalapriya, Chandrasekaran A1 - Romano Blasco, Maria Carmen A1 - Thiel, Marco A1 - Schwarz, Udo A1 - Kurths, Jürgen A1 - Simonotto, Jennifer A1 - Furman, Michael A1 - Ditto, William L. A1 - Carney, Paul R. T1 - Analysis of high-resulution microelectrode EEG recordings in an animal model of spontaneous limbic seizures Y1 - 2009 UR - http://www.worldscinet.com/ijbc/ijbc.shtml U6 - https://doi.org/10.1142/S0218127409023226 SN - 0218-1274 ER - TY - JOUR A1 - Marwan, Norbert A1 - Kurths, Jürgen A1 - Thomsen, Jesper Skovhus A1 - Felsenberg, Dieter A1 - Saparin, Peter T1 - Three-dimensional quantification of structures in trabecular bone using measures of complexity N2 - The study of pathological changes of bone is an important task in diagnostic procedures of patients with metabolic bone diseases such as osteoporosis as well as in monitoring the health state of astronauts during long-term space flights. The recent availability of high-resolution three-dimensional (3D) imaging of bone challenges the development of data analysis techniques able to assess changes of the 3D microarchitecture of trabecular bone. We introduce an approach based on spatial geometrical properties and define structural measures of complexity for 3D image analysis. These measures evaluate different aspects of organization and complexity of 3D structures, such as complexity of its surface or shape variability. We apply these measures to 3D data acquired by high-resolution microcomputed tomography (mu CT) from human proximal tibiae and lumbar vertebrae at different stages of osteoporotic bone loss. The outcome is compared to the results of conventional static histomorphometry and exhibits clear relationships between the analyzed geometrical features of trabecular bone and loss of bone density, but also indicate that the measures reveal additional information about the structural composition of bone, which were not revealed by the static histomorphometry. Finally, we have studied the dependency of the developed measures of complexity on the spatial resolution of the mu CT data sets. Y1 - 2009 UR - http://pre.aps.org/ U6 - https://doi.org/10.1103/Physreve.79.021903 SN - 1539-3755 ER - TY - JOUR A1 - Li, Ping A1 - Chen, Maoyin A1 - Wu, Ye A1 - Kurths, Jürgen T1 - Matrix-measure criterion for synchronization in coupled-map networks N2 - We present conditions for the local and global synchronizations in coupled-map networks using the matrix measure approach. In contrast to many existing synchronization conditions, the proposed synchronization criteria do not depend on the solution of the synchronous state and give less limitation on the network connections. Numerical simulations of the coupled quadratic maps demonstrate the potentials of our main results. Y1 - 2009 UR - http://pre.aps.org/ U6 - https://doi.org/10.1103/Physreve.79.067102 SN - 1539-3755 ER - TY - JOUR A1 - Marwan, Norbert A1 - Kurths, Jürgen T1 - Comment on "Stochastic analysis of recurrence plots with applications to the detection of deterministic signals" by Rohde et al. : [Physica D 237 (2008) 619-629] N2 - In the recent article "Stochastic analysis of recurrence plots with applications to the detection of deterministic signals" (Physica D 237 (2008) 619-629), Rohde et al. stated that the performance of RQA in order to detect deterministic signals would be below traditional and well-known detectors. However, we have concerns about such a general statement. Based on our own studies we cannot confirm their conclusions. Our findings suggest that the measures of complexity provided by RQA are useful detectors outperforming well-known traditional detectors, in particular for the detection of signals of complex systems, with phase differences or signals modified due to the measurement process. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/01672789 U6 - https://doi.org/10.1016/j.physd.2009.04.018 SN - 0167-2789 ER - TY - JOUR A1 - Florence, Gerson A1 - Dahlem, Markus A. A1 - Almeida, Antônio-Carlos G. A1 - Bassani, José W. M. A1 - Kurths, Jürgen T1 - The role of extracellular potassium dynamics in the different stages of ictal bursting and spreading depression : a computational study N2 - Experimental evidences point Out the participation of nonsynaptic mechanisms (e.g., fluctuations in extracellular tons) in epileptiform bursting and spreading depression (SD). During these abnormal oscillatory patterns, it is observed an increase of extracellular potassium concentration [K+](o) and a decrease of extracellular calcium concentration [Ca2+](o) which raises the neuronal excitability. However, whether the high [K+](o) triggers and propagates these abnormal neuronal activities or plays a secondary role into this process is unclear. To better understand the influence of extracellular potassium dynamics in these oscillatory patterns, the experimental conditions of high [K+](o) and zero [Ca2+](o) were replicated in an extended Golomb model where we added important regulatory mechanisms of ion concentration as Na+-K+ pump, ion diffusion and glial buffering. Within these Conditions, simulations of the cell model exhibit seizure-like discharges (ictal bursting). The SD was elicited by the interruption of the Na+- K+ pump activity, mimicking the effect of cellular hypoxia (an experimental protocol to elicit SD, the hypoxia-induced SD). We used the bifurcation theory and the fast-slow method to analyze the interference of K+ dynamics in the cellular excitability. This analysis indicates that the system loses its stability at a high [K+](o), transiting to an elevated state of neuronal excitability. Effects of high [K+](o), are observed in different stages of ictal bursting and SD. In the initial stage, the increase of [K+](o) creates favorable conditions to trigger both oscillatory patterns. During the neuronal activity, a continuous growth of [K+](o) by outward K+ flow depresses K+ Currents in a positive feedback way. At the last stage, due to the depression of K+ currents, the Na+-K+ pump is the main mechanism in the end of neuronal activity. Thus, this work suggests that [K+](o) dynamics may play a fundamental role in these abnormal oscillatory patterns. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00225193 U6 - https://doi.org/10.1016/j.jtbi.2009.01.032 SN - 0022-5193 ER - TY - JOUR A1 - Donges, Jonathan Friedemann A1 - Zou, Yong A1 - Marwan, Norbert A1 - Kurths, Jürgen T1 - Complex networks in climate dynamics : comparing linear and nonlinear network construction methods N2 - Complex network theory provides a powerful framework to statistically investigate the topology of local and non- local statistical interrelationships, i.e. teleconnections, in the climate system. Climate networks constructed from the same global climatological data set using the linear Pearson correlation coefficient or the nonlinear mutual information as a measure of dynamical similarity between regions, are compared systematically on local, mesoscopic and global topological scales. A high degree of similarity is observed on the local and mesoscopic topological scales for surface air temperature fields taken from AOGCM and reanalysis data sets. We find larger differences on the global scale, particularly in the betweenness centrality field. The global scale view on climate networks obtained using mutual information offers promising new perspectives for detecting network structures based on nonlinear physical processes in the climate system. Y1 - 2009 UR - http://www.springerlink.com/content/1951-6355 U6 - https://doi.org/10.1140/epjst/e2009-01098-2 SN - 1951-6355 ER - TY - JOUR A1 - Wessel, Niels A1 - Riedl, Maik A1 - Kurths, Jürgen T1 - Is the normal heart rate "chaotic" due to respiration? N2 - The incidence of cardiovascular diseases increases with the growth of the human population and an aging society, leading to very high expenses in the public health system. Therefore, it is challenging to develop sophisticated methods in order to improve medical diagnostics. The question whether the normal heart rate is chaotic or not is an attempt to elucidate the underlying mechanisms of cardiovascular dynamics and therefore a highly controversial topical challenge. In this contribution we demonstrate that linear and nonlinear parameters allow us to separate completely the data sets of the three groups provided for this controversial topic in nonlinear dynamics. The question whether these time series are chaotic or not cannot be answered satisfactorily without investigating the underlying mechanisms leading to them. We give an example of the dominant influence of respiration on heart beat dynamics, which shows that observed fluctuations can be mostly explained by respiratory modulations of heart rate and blood pressure (coefficient of determination: 96%). Therefore, we recommend reformulating the following initial question: "Is the normal heart rate chaotic?" We rather ask the following: " Is the normal heart rate 'chaotic' due to respiration?" Y1 - 2009 UR - http://ojps.aip.org/chaos/ U6 - https://doi.org/10.1063/1.3133128 SN - 1054-1500 ER - TY - JOUR A1 - Wu, Ye A1 - Li, Ping A1 - Chen, Maoyin A1 - Xiao, Jinghua A1 - Kurths, Jürgen T1 - Response of scale-free networks with community structure to external stimuli N2 - The response of scale-free networks with community structure to external stimuli is studied. By disturbing some nodes with different strategies, it is shown that the robustness of this kind of network can be enhanced due to the existence of communities in the networks. Some of the response patterns are found to coincide with topological communities. We show that such phenomena also occur in the cat brain network which is an example of a scale-free like network with community structure. Our results provide insights into the relationship between network topology and the functional organization in complex networks from another viewpoint. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/03784371 U6 - https://doi.org/10.1016/j.physa.2009.03.037 SN - 0378-4371 ER -