TY  - GEN
A1  - Johnson, Kim L.
A1  - Ramm, Sascha
A1  - Kappel, Christian
A1  - Ward, Sally
A1  - Leyser, Ottoline
A1  - Sakamoto, Tomoaki
A1  - Kurata, Tetsuya
A1  - Bevan, Michael W.
A1  - Lenhard, Michael
T1  - The tinkerbell (tink) mutation identifies the dual-specificity MAPK phosphatase INDOLE- 3-BUTYRIC ACID-RESPONSE5 (IBR5) as a novel regulator of organ size in Arabidopsis
T2  - PLoS ONE
N2  - Mitogen-activated dual-specificity MAPK phosphatases are important negative regulators in the MAPK signalling pathways responsible for many essential processes in plants. In a screen for mutants with reduced organ size we have identified a mutation in the active site of the dual-specificity MAPK phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) that we named tinkerbell (tink) due to its small size. Analysis of the tink mutant indicates that IBR5 acts as a novel regulator of organ size that changes the rate of growth in petals and leaves. Organ size and shape regulation by IBR5 acts independently of the KLU growth-regulatory pathway. Microarray analysis of tink/ibr5-6 mutants identified a likely role for this phosphatase in male gametophyte development. We show that IBR5 may influence the size and shape of petals through auxin and TCP growth regulatory pathways.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 427 
KW  - class-i
KW  - protein phosphatase
KW  - auxin
KW  - responses
KW  - thaliana
KW  - kinase
KW  - growth
KW  - interacts
KW  - distinct
KW  - pathway
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-410245
ER  - 
TY  - JOUR
A1  - Johnson, Kim L.
A1  - Ramm, Sascha
A1  - Kappel, Christian
A1  - Ward, Sally
A1  - Leyser, Ottoline
A1  - Sakamoto, Tomoaki
A1  - Kurata, Tetsuya
A1  - Bevan, Michael W.
A1  - Lenhard, Michael
T1  - The Tinkerbell (Tink) Mutation Identifies the Dual-Specificity MAPK Phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) as a Novel Regulator of Organ Size in Arabidopsis
JF  - PLoS one
N2  - Mitogen-activated dual-specificity MAPK phosphatases are important negative regulators in the MAPK signalling pathways responsible for many essential processes in plants. In a screen for mutants with reduced organ size we have identified a mutation in the active site of the dual-specificity MAPK phosphatase INDOLE-3-BUTYRIC ACID-RESPONSE5 (IBR5) that we named tinkerbell (tink) due to its small size. Analysis of the tink mutant indicates that IBR5 acts as a novel regulator of organ size that changes the rate of growth in petals and leaves. Organ size and shape regulation by IBR5 acts independently of the KLU growth-regulatory pathway. Microarray analysis of tink/ibr5-6 mutants identified a likely role for this phosphatase in male gametophyte development. We show that IBR5 may influence the size and shape of petals through auxin and TCP growth regulatory pathways.
Y1  - 2015
U6  - https://doi.org/10.1371/journal.pone.0131103
SN  - 1932-6203
VL  - 10
IS  - 7
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Johnson, Kim L.
A1  - Lenhard, Michael
T1  - Genetic control of plant organ growth
JF  - New phytologist : international journal of plant science
N2  - The growth of plant organs is under genetic control. Work in model species has identified a considerable number of genes that regulate different aspects of organ growth. This has led to an increasingly detailed knowledge about how the basic cellular processes underlying organ growth are controlled, and which factors determine when proliferation gives way to expansion, with this transition emerging as a critical decision point during primordium growth. Progress has been made in elucidating the genetic basis of allometric growth and the role of tissue polarity in shaping organs. We are also beginning to understand how the mechanisms that determine organ identity influence local growth behaviour to generate organs with characteristic sizes and shapes. Lastly, growth needs to be coordinated at several levels, for example between different cell layers and different regions within one organ, and the genetic basis for such coordination is being elucidated. However, despite these impressive advances, a number of basic questions are still not fully answered, for example, whether and how a growing primordium keeps track of its size. Answering these questions will likely depend on including additional approaches that are gaining in power and popularity, such as combined live imaging and modelling.
KW  - growth coordination
KW  - organ growth
KW  - organ identity
KW  - organ shape
KW  - organ size
Y1  - 2011
U6  - https://doi.org/10.1111/j.1469-8137.2011.03737.x
SN  - 0028-646X
VL  - 191
IS  - 2
SP  - 319
EP  - 333
PB  - Wiley-Blackwell
CY  - Malden
ER  -