TY  - JOUR
A1  - Gambinossi, Filippo
A1  - Sefcik, Lauren S.
A1  - Wischerhoff, Erik
A1  - Laschewsky, André
A1  - Ferri, James K.
T1  - Engineering Adhesion to Thermoresponsive Substrates: Effect of Polymer Composition on Liquid-Liquid-Solid Wetting
JF  - ACS applied materials & interfaces
N2  - Adhesion control in liquidliquidsolid systems represents a challenge for applications ranging from self-cleaning to biocompatibility of engineered materials. By using responsive polymer chemistry and molecular self-assembly, adhesion at solid/liquid interfaces can be achieved and modulated by external stimuli. Here, we utilize thermosensitive polymeric materials based on random copolymers of di(ethylene glycol) methyl ether methacrylate (x = MEO(2)MA) and oligo(ethylene glycol) methyl ether methacrylate (y = OEGMA), that is, P(MEO(2)MA(x)-co-OEGMA(y)), to investigate the role of hydrophobicity on the phenomenon of adhesion. The copolymer ratio (x/y) dictates macromolecular changes enabling control of the hydrophilic-to-lipophilic balance (HBL) of the polymer brushes through external triggers such as ionic strength and temperature. We discuss the HBL of the thermobrushes in terms of the surface energy of the substrate by measuring the contact angle at waterdecaneP(MEO(2)MA(x)-co-OEGMA(y)) brush contact line as a function of polymer composition and temperature. Solid supported polyelectrolyte layers grafted with P(MEO(2)MA(x)-co-OEGMA(y)) display a transition in the wettability that is related to the lower critical solution temperature of the polymer brushes. Using experimental observation of the hydrophilic to hydrophobic transition by the contact angle, we extract the underlying energetics associated with liquidliquidsolid adhesion as a function of the copolymer ratio. The change in cellular attachment on P(MEO(2)MA(x)-co-OEGMA(y)) substrates of variable (x/y) composition demonstrates the subtle role of compositional tuning on the ability to control liquidliquidsolid adhesion in biological applications.
KW  - water/decane contact angle
KW  - thermoresponsive substrates
KW  - di(ethylene glycol) methy ether methacrylate
KW  - oligo(ethylene glycol) methyl ether methacrylate
KW  - hydrophilic-to-lipophilic balance
KW  - programmable adhesion
Y1  - 2015
U6  - https://doi.org/10.1021/am507418m
SN  - 1944-8244
VL  - 7
IS  - 4
SP  - 2518
EP  - 2528
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Cramer, Ashley D.
A1  - Gambinossi, Filippo
A1  - Wischerhoff, Erik
A1  - Laschewsky, André
A1  - Miller, Reinhard
A1  - Ferri, James K.
T1  - Flexible thermoresponsive nanomembranes at the aqueous-air interface
JF  - Chemical communications
N2  - A synthetic pathway is described to construct thermoresponsive freestanding nanomembranes at the aqueous-air interface of a pendant drop. Dynamic control of the reaction kinetics allows formation of viscoelastic interfaces supporting anisotropic stresses and mechanical stability, which can be tuned by external stimuli.
Y1  - 2015
U6  - https://doi.org/10.1039/c4cc07359b
SN  - 1359-7345
SN  - 1364-548X
VL  - 51
IS  - 5
SP  - 877
EP  - 880
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  -