TY  - JOUR
A1  - Contin, Andrea
A1  - Frasca, Stefano
A1  - Vivekananthan, Jeevanthi
A1  - Leimkühler, Silke
A1  - Wollenberger, Ursula
A1  - Plumere, Nicolas
A1  - Schuhmann, Wolfgang
T1  - A pH Responsive Redox Hydrogel for Electrochemical Detection of Redox Silent Biocatalytic Processes. Control of Hydrogel Solvation
JF  - Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis
N2  - The control of bioelectrocatalytic processes by external stimuli for the indirect detection of non-redox active species was achieved using an esterase and a redox enzyme both integrated within a redox hydrogel. The poly( vinyl) imidazole Os(bpy)(2)Cl hydrogel displays pH-responsive properties. The esterase catalysed reaction leads to a local pH decrease causing protonation of imidazole moieties thus increasing hydrogel solvation and mobility of the tethered Os-complexes. This is the key step to enable improved electron transfer between an aldehyde oxidoreductase and the polymer-bound Os-complexes. The off-on switch is further integrated in a biofuel cell system for self-powered signal generation.
KW  - pH responsive hydrogel
KW  - External stimuli
KW  - Biofuel cell
KW  - Self-powered biosensor
KW  - Solvation
Y1  - 2015
U6  - https://doi.org/10.1002/elan.201400621
SN  - 1040-0397
SN  - 1521-4109
VL  - 27
IS  - 4
SP  - 938
EP  - 944
PB  - Wiley-VCH
CY  - Weinheim
ER  -