TY  - JOUR
A1  - David Coy, Ericsson
A1  - Enrique Cuca, Luis
A1  - Sefkow, Michael
T1  - Pd-NHC catalyzed biaryl coupling by direct C-H Activation-A Novel strategy for the synthesis of dibenzocyclooctane lignans
JF  - Synthetic communications : an international journal for rapid communication of synthetic organic chemistry
N2  - Cross-coupling reactions, such as Buchwald-Hartwig arylamination and direct intramolecular biaryl coupling by C-H activation, were carried out using various Palladium-N-heterocyclic carbenes (Pd-NHC) as catalysts. The yields were good to excellent. The latter strategy was adopted to transform two dibenzylbutane lignans, isolated from the leaves of Ocotea macrophylla (Lauraceae), into the corresponding dibenzocyclooctane lignans in good overall yields. Supplemental materials are available for this article. Go to the publisher's online edition of Synthetic Communications (R) to view the free supplemental file.
KW  - Cross-coupling reactions
KW  - dibenzylbutane
KW  - dibenzocyclooctane
KW  - lignans
KW  - N-heterocyclic carbenes (NHC)
Y1  - 2011
U6  - https://doi.org/10.1080/00397910903531755
SN  - 0039-7911
VL  - 41
IS  - 1
SP  - 41
EP  - 51
PB  - Taylor & Francis Group
CY  - Philadelphia
ER  -