TY  - JOUR
A1  - Kerubo, Leonidah Omosa
A1  - Midiwo, Jacob Ogweno
A1  - Derese, Solomon
A1  - Langat, Moses K.
A1  - Akala, Hoseah M.
A1  - Waters, Norman C.
A1  - Peter, Martin
A1  - Heydenreich, Matthias
T1  - Antiplasmodial activity of compounds from the surface exudates of senecio roseiflorus
JF  - Natural product communications : an international journal for communications and reviews
N2  - From the surface exudates of Senecio roseiflorus fourteen known methylated flavonoids and one phenol were isolated and characterized. The structures of these compounds were determined on the basis of their spectroscopic analysis. The surface exudate and the flavonoids isolated showed moderate to good antiplasmodial activity with 5,4'-dihydroxy-7-dimethoxyflavanone having the highest activity against chloroquine-sensitive (D6) and resistant (W2) strains of Plasmodium falciparum, with IC50 values of 3.2 +/- 0.8 and 4.4 +/- 0.01 mu g/mL respectively.
KW  - Senecio roseiflorus
KW  - Asteraceae
KW  - Surface exudates
KW  - Antiplasmodial activity
Y1  - 2013
SN  - 1934-578X
VL  - 8
IS  - 2
SP  - 175
EP  - 176
PB  - NPC
CY  - Westerville
ER  -