TY  - JOUR
A1  - Germer, Antje
A1  - Mugge, Clemens
A1  - Peter, Martin G.
A1  - Rottmann, Antje
A1  - Kleinpeter, Erich
T1  - Solution- and bound-state conformational study of N,N',N''-triacetyl chitotriose and other analogous potential inhibitors of hevamine: Application of trNOESY and STD NMR spectroscopy
N2  - The soln.-state conformations of N,N',N''-triacetyl chitotriose (1) and other potential chitinase inhibitors 2-4 were studied using a combination of NMR spectroscopy (NOESY) and mol. mechanics calcns. Detn. solely of the global energy min. conformation was found to be insufficient for an agreement with the NMR results. An appropriate consistency between the NMR exptl. data and theor. calcns. was only reached by assessing the structures as population-weighted av. conformers based on Boltzmann distributions derived from the calcd. relative energies. Analogies, but also particular differences, between the synthetic compds. 2-4 and the naturally-occurring N,N',N''-triacetyl chitotriose were found. Furthermore, the conformation of compds. 1 and 2 when bound to hevamine was also studied using transferred NOESY expts. and the binding process was found to impart a level of conformational restriction on the ligands. The preferred conformation as detd. for 1 in the bound state to hevamine belonged to one of the conformational families found for the compd. when free in soln., although full characterization of the bound-state conformations was impeded due to severe signal overlap. Satn. transfer difference NMR expts. were also employed to analyze the binding epitopes of the bound compds. We thus detd. that it is mainly the acetyl amido groups of the trisaccharide and the heterocyclic moiety which are in close contact with hevamine.
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Germer, Antje
A1  - Peter, Martin G.
A1  - Kleinpeter, Erich
T1  - Solution-state conformational study of the hevamine inhibitor allosamidin and six potential inhibitor analogues by NMR spectroscopy and molecular modeling
N2  - The soln.-state conformations of the hevamine inhibitor allosamidin and six potential inhibitor analogs were studied by various NMR spectroscopic techniques and mol. modeling using force field calcns. Detn. solely of the global energy min. conformation was found to be insufficient for consensus with the NMR results, and agreement between the NMR exptl. data and the theor. calcns. was only reached by assessing the structures as population-weighted av. conformers on the basis of Boltzmann distributions derived from the calcd. relative energies. The conformations of the glycosidic linkages in the compds. were found to be similar when the sugar residues were the same, but differences were markedly evident otherwise and also for the various heterocyclic group linkages. The binding of the compds. to hevamine, which may also complex to chitinases in general, was assessed using HMQC, transfer-NOESY, and both 1-D and 2-D satn. transfer difference NMR expts. Under the conditions employed, only allosamidin was implicated to be bound to hevamine, and then only by HMQC with the dipolar coupling-based expts. failing to substantiate the formation of the complex. However, the results are consistent with the biochem. activities of the compds. whereby only allosamidin has been shown to act as a competitive inhibitor.
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Haebel, Sophie
A1  - Bahrke, Sven
A1  - Peter, Martin G.
T1  - Quantitative sequencing of complex mixtures of heterochitooligosaccharides by vMALDI-linear ion trap mass spectrometry
N2  - Heterochitooligosaccharides possess interesting biol. properties. Isobaric mixts. of such linear heterochitooligosaccharides can be obtained by chem. or enzymic degrdn. of chitosan. However, the sepn. of such mixts. is a challenging anal. problem which is so far unresolved. It is shown that these isobaric mixts. can be sequenced and quantified simultaneously using std. derivatization and multistage tandem mass spectrometric techniques. A linear ion trap mass spectrometer equipped with a vacuum matrix-assisted laser desorption ionization (vMALDI) source is used to perform MS2 as well as MS3 expts. [on SciFinder (R)].
Y1  - 2007
UR  - http://pubs.acs.org/loi/ancham
U6  - https://doi.org/10.1021/Ac062254u
SN  - 0003-2700
ER  - 
TY  - JOUR
A1  - Haebel, Sophie
A1  - Peter-Katalinic, Jasna
A1  - Peter, Martin G.
T1  - Mass spectrometry of chitooligosaccharides
Y1  - 1997
SN  - 88-86889- 01-1
ER  - 
TY  - JOUR
A1  - Houston, Douglas R.
A1  - Shiomi, Kazuro
A1  - Arai, Noriko
A1  - Omura, Satoshi
A1  - Peter, Martin G.
A1  - Turberg, Andreas
A1  - Synstad, Bjoenar
A1  - Eijsink, Vincent G. H.
A1  - Van Aalten, Daan M. F.
T1  - High-resolution structures of a chitinase complexed with natural product cyclopentapeptide inhibitors : mimicry of carbohydrate substrate
N2  - Over the past years, family 18 chitinases have been validated as potential targets for the design of drugs against human pathogens that contain or interact with chitin during their normal life cycles. Thus far, only one potent chitinase inhibitor has been described in detail, the pseudotrisaccharide allosamidin. Recently, however, two potent natural-product cyclopentapeptide chitinase inhibitors, argifin and argadin, were reported. Here, we describe high- resoln. crystal structures that reveal the details of the interactions of these cyclopeptides with a family 18 chitinase. The structures are examples of complexes of a carbohydrate-processing enzyme with high-affinity peptide-based inhibitors and show in detail how the peptide backbone and side chains mimic the interactions of the enzyme with chitooligosaccharides. Together with enzymol. characterization, the structures explain why argadin shows an order of magnitude stronger inhibition than allosamidin, whereas argifin shows weaker inhibition. The peptides bind to the chitinase in remarkably different ways, which may explain the differences in inhibition consts. The two complexes provide a basis for structure-based design of potent chitinase inhibitors, accessible by std. peptide chem.
Y1  - 2002
ER  - 
TY  - JOUR
A1  - Issaree, Arisara
A1  - Vijayakrishnan, Balakumar
A1  - Abdelnur, Patricia V.
A1  - Corilo, Yuri E.
A1  - Riccio, Maria F.
A1  - Sanvido, Gustavo B.
A1  - Eberlin, Marcos N.
A1  - Peter, Martin G.
T1  - Mass spectrometry of aminoglucan oligosaccharides using electrospray ionization MS/MS and MS/MS/MS
Y1  - 2009
ER  - 
TY  - JOUR
A1  - Juma, Wanyama P.
A1  - Akala, Hoseah M.
A1  - Eyase, Fredrick L.
A1  - Muiva, Lois M.
A1  - Heydenreich, Matthias
A1  - Okalebo, Faith A.
A1  - Gitu, Peter M.
A1  - Peter, Martin G.
A1  - Walsh, Douglas S.
A1  - Imbuga, Mabel
A1  - Yenesew, Abiy
T1  - Terpurinflavone an antiplasmodial flavone from the stem of Tephrosia Purpurea
JF  - Phytochemistry letters
N2  - The stem extract of Tephrosia purpurea showed antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquine-resistant) strains of Plasmodium falciparum with IC(50) values of 10.47 +/- 2.22 mu g/ml and 12.06 +/- 2.54 mu g/ml, respectively. A new prenylated flavone, named terpurinflavone, along with the known compounds lanceolatin A, (-)-semiglabrin and lanceolatin B have been isolated from this extract. The new compound, terpurinflavone, showed the highest antiplasmodial activity with IC(50) values of 3.12 +/- 0.28 mu M (D6) and 6.26 +/- 2.66 mu M (W2). The structures were determined on the basis of spectroscopic evidence.
KW  - Tephrosia purpurea
KW  - Leguminosae
KW  - Stem
KW  - Flavone
KW  - Terpurinflavone
KW  - Antiplasmodial
Y1  - 2011
U6  - https://doi.org/10.1016/j.phytol.2011.02.010
SN  - 1874-3900
VL  - 4
IS  - 2
SP  - 176
EP  - 178
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - JOUR
A1  - Kaatz, Helvi
A1  - Streffer, Katrin
A1  - Wollenberger, Ursula
A1  - Peter, Martin G.
T1  - Inhibition of mushroom tyrosinase by kojic acid octanoates
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Kamlage, Stefan
A1  - Sefkow, Michael
A1  - Peter, Martin G.
T1  - A short synthesis of biologically active lignan analogues
N2  - beta-Benzyl-gamma-butyrolactones were synthesized in four transition metal catalysed reactions from butynediol, and alkylated to afford new, biologically active lignan analogues.
Y1  - 2001
ER  - 
TY  - JOUR
A1  - Kamlage, Stefan
A1  - Sefkow, Michael
A1  - Peter, Martin G.
T1  - Cross coupling of benzylic bromides and vinyl stannanes
Y1  - 1999
ER  - 
TY  - JOUR
A1  - Kamlage, Stefan
A1  - Sefkow, Michael
A1  - Zimmermann, Nicole
A1  - Peter, Martin G.
T1  - Concise synthesis of (+)-beta-benzyl gamma-butyrolactones from butynediol
Y1  - 2002
ER  - 
TY  - GEN
A1  - Kort, C. A. D. de
A1  - Peter, Martin G.
A1  - Koopmanschap, A. B.
T1  - Binding and degradation of juvenile hormone III by haemolymph proteins of the Colorado potato beetle: a re-examination
N2  - The haemolymph of the adult Colorado potato beetle, Lepinotarsa decemlineata Say, contains a high molecular weight (MW > 200,000) JH-III specific binding protein. The Kd value of the protein for racemic JH-III is 1.3 ± 0.2 × 10−7 M. It has a lower affinity for racemic JH-I and it does not bind JH-III-diol or JH-III-acid. The binding protein does discriminate between the enantiomers of synthetic, racemic JH-III as was determined by stereochemical anaysis of the bound and the free JH-III. Incubation of racemic JH-III with crude haemolymph results in preferential formation of (10S)-JH-III-acid, the unnatural configuration. The JH-esterase present in L. decemlineata haemolymph is not enantioselective. It is concluded that the most important function of the binding protein is that of a specific carrier, protecting the natural hormone against degradation by esterases. The carrier does not protect JH-I as efficiently as the lower homologue.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 068 
KW  - Juvenile hormone
KW  - Leptinotarsa decemlineata
KW  - JH-III-specific carrier protein
KW  - enantioselectivity
Y1  - 1983
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16777
ER  - 
TY  - JOUR
A1  - Krösche, Ch.
A1  - Peter, Martin G.
T1  - Detection of melanochromes by MALDI-TOF mass spectrometry
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Krösche, Christian
A1  - Crescenzi, Orlando
A1  - Hoffbauer, Wilfried
A1  - Jansen, Martin
A1  - Napolitano, Alessandra
A1  - Prota, Guiseppe
A1  - Peter, Martin G.
T1  - Synthesis of dopamines labelled with 13C in the alpha- or beta-side chain positions, and their application for structure studies on melanins by solid state NMR spectroscopy
Y1  - 1994
ER  - 
TY  - JOUR
A1  - Letzel, Matthias C.
A1  - Peter-Katalinic, Jasna
A1  - Peter, Martin G.
T1  - Mass spectrometry of chitin and chitosan oligosaccharides
Y1  - 2001
ER  - 
TY  - JOUR
A1  - Letzel, Matthias C.
A1  - Synstad, Bjoenar
A1  - Eijsink, Vincent G. H.
A1  - Peter-Katalinic, Jasna
A1  - Peter, Martin G.
T1  - Libraries of chito-oligosaccharides of mixed acetylation patterns and their interactions with chitinases
Y1  - 1999
SN  - 3-9806494-5-8
ER  - 
TY  - JOUR
A1  - Ley, J. P.
A1  - Peter, Martin G.
T1  - Synthesis of L-histidine and (-)-spinacine chitooligosyl amides
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Ley, J. P.
A1  - Peter, Martin G.
T1  - Synthesis of N-(2-Acetamido-2-deoxy-ß-D-glucopyranosyl)- and of N-(N,N-Diacetylchitobiosyl)-amide of lhistidine
Y1  - 1994
SN  - 0039-7881
ER  - 
TY  - JOUR
A1  - Ley, J. P.
A1  - Schweikart, F.
A1  - Peter, Martin G.
T1  - Chitinase inhibitors
Y1  - 1997
ER  - 
TY  - JOUR
A1  - Londershausen, M.
A1  - Turberg, Andreas
A1  - Bieseler, Barbara
A1  - Lennarz, M.
A1  - Peter, Martin G.
T1  - Characterization and Inhibitor Studies of Chitinases from Parasitic Blowfly (Lucilia cuprina), Tick (Boophilus micoplus), Intestinale Nematode (Haemonchus contortus), and a Bean (Phaseolus vulgaris)
Y1  - 1996
ER  - 
TY  - JOUR
A1  - Londershausen, M.
A1  - Turberg, Andreas
A1  - Spindler-Barth, Margarethe
A1  - Peter, Martin G.
T1  - Screening Test for Insecticides Interfering with Cuticular Sclerotization
Y1  - 1996
ER  - 
TY  - JOUR
A1  - López-Franco, Yolanda L.
A1  - Calderón de la Barca, Ana M.
A1  - Valdez, Miguel A.
A1  - Peter, Martin G.
A1  - Rinaudo, Marguerite
A1  - Chambat, Gérard
A1  - Goycoolea, Francisco M.
T1  - Structural characterization of mesquite (Prosopis velutina) gum and its fractions
N2  - Structural and physicochem. characteristics of mesquite gum (from Prosopis velutina) were investigated using FT- IR spectroscopic, mass spectrometric and chromatog. methods. Four fractions (F-I, F-IIa, F-IIb and F-III) were isolated by hydrophobic interaction chromatog. The samples were characterized and analyzed for their monosaccharide and oligomers compn. by high performance anion-exchange chromatog. with pulsed amperometric detection (HPAEC-PAD). L-Arabinose (L-Ara) and D-galactose (D-Gal) were found as the main carbohydrate constituent residues in the polysaccharides from mesquite gum and their ratio (L-Ara/D-Gal) varied within the range 2.54 to 3.06 among the various fractions. Small amts. of D- glucose (D-Glc), D-mannose (D-Man) and D-xylose (D-Xyl) were also detected, particularly in Fractions IIa, IIb and III. IR spectroscopy identified polysaccharides and protein in all the samples. Data from mass spectrometry (MALDI-TOF MS) was consistent with the idea that the structure corresponding to the periphereal chains of Fraction I is predominantly a chain of pentoses attached to uronic acid. [on SciFinder (R)].
Y1  - 2008
UR  - http://www3.interscience.wiley.com/journal/77002860/home?CRETRY=1&SRETRY=0
U6  - https://doi.org/10.1002/mabi.200700285
SN  - 1616-5187
ER  - 
TY  - JOUR
A1  - Menezes, Bruno M.
A1  - Grigolon, Lisanne
A1  - Todorovic, Zoran
A1  - Peter, Martin G.
A1  - Franco, Telma T.
T1  - On the depolymerization of chitosan by papain : a re-assessment
Y1  - 2009
ER  - 
TY  - JOUR
A1  - Mengibar, M.
A1  - Ganan, M.
A1  - Miralles, B.
A1  - Carrascosa, A. V.
A1  - Martinez-Rodriguez, Adolfo J.
A1  - Peter, Martin G.
A1  - Heras, A.
T1  - Antibacterial activity of products of depolymerization of chitosans with lysozyme and chitosanase against Campylobacter jejuni
JF  - Carbohydrate polymers : an international journal devoted to scientific and technological aspects of industrially important polysaccharides
N2  - Chitosan has several biological properties useful for the food industry, but the most attractive is its potential use as a food preservative of natural origin due to its antimicrobial activity against a wide range of food-borne microorganisms. Among food-borne pathogens, Campylobacter jejuni and related species are recognised as the most common causes of bacterial food-borne diarrhoeal disease throughout the world. Recently, it has been demonstrated that campylobacters are highly sensitive to chitosan. Even though chitosan is known to have important functional activities, poor solubility makes them difficult to use in food and biomedical applications. Unlike chitosan, the low viscosity and good solubility of chitosan oligosaccharides (COS) make them especially attractive in an important number of useful applications. In the present work, the effect of different COS on C. jejuni was investigated. Variables such as the physicochemical characteristics of chitosan and the enzyme used in COS preparation were studied. The COS had been fractioned using ultrafiltration membranes and each fraction was characterized regarding its FA and molecular weight distribution. It has been demonstrated that the biological properties of COS on Campylobacter depend on the composition of the fraction analysed. COS prepared by enzymatic hydrolysis with chitosanase were more active against Campylobacter that lysozyme-derived COS, and this behaviour seems to be related with the acetylation of the chains. On the other hand. the 10-30 kDa fraction was the most active COS fraction, independently of the enzyme used for the hydrolysis. These results have shown that COS could be useful as antimicrobial in the control of C. jejuni.
KW  - Campylobacter jejuni
KW  - Chitooligosaccharides
KW  - Chitosanase
KW  - Lysozyme
KW  - Depolymerization
Y1  - 2011
U6  - https://doi.org/10.1016/j.carbpol.2010.04.042
SN  - 0144-8617
VL  - 84
IS  - 2
SP  - 844
EP  - 848
PB  - Elsevier
CY  - Oxford
ER  - 
TY  - JOUR
A1  - Miessner, Merle
A1  - Peter, Martin G.
A1  - Vincent, Julian F. V.
T1  - Preparation of Insect-Cuticle-Like Biomimetic Materials
N2  - A model system of tanning of a protein matrix within a fibrous structure, such as most commonly found in insect cuticle, was developed, using the cellulose of paper in place of chitin. The paper was impregnated with a tripeptide, DOPA-Gly-Gly, or a protein (BSA) plus catechol and treated with tyrosinase to oxidize the catechol. The resulting material was waterproof and had very high wet strength. If the material was wetted and dried repeatedly its water retention decreased by a factor of at least two.
Y1  - 2001
ER  - 
TY  - GEN
A1  - Moerschbacher, Bruno
A1  - Jaworska, Małgorzata
A1  - Peter, Martin G.
T1  - Obituary of George A.F. Roberts (1939-2018)
T2  - Reactive & functional polymers
Y1  - 2020
U6  - https://doi.org/10.1016/j.reactfunctpolym.2020.104711
SN  - 1381-5148
SN  - 1873-166X
VL  - 156
PB  - Elsevier
CY  - Amsterdam [u.a.]
ER  - 
TY  - JOUR
A1  - Norledge, Brian V.
A1  - Lambeir, Anne M.
A1  - Abagyan, Ruben
A1  - Rottmann, Antje
A1  - Fernendez, Anna M.
A1  - Filimonov, Vladimir V.
A1  - Peter, Martin G.
A1  - Wierenga, Rik K.
T1  - Modeling, mutagenesis, and structural studies on the fully conserved phoshate-binding loop (Loop 8) of triosephosphate isomerase : toward a new substrate specificity
Y1  - 2001
UR  - http://www3.interscience.wiley.com/journal/36176/toc
SN  - 0887-2585
ER  - 
TY  - JOUR
A1  - Oliveira, Enio N.
A1  - el Gueddari, Nour E.
A1  - Moerschbacher, Bruno M.
A1  - Peter, Martin G.
A1  - Franco, Telma T.
T1  - Growth of phytopathogenic fungi in the presence of partially acetylated chitooligosaccharides
N2  - Four phytopathogenic fungi were cultivated up to six days in media contg. chitooligosaccharide mixts. differing in av. DP and F A. The three different mixts. were named Q3 (which contained oligosaccharides of DP2-DP10, with DP2-DP7 as main components), Q2 (which contained oligosaccharides of DP2-DP12, with DP2-DP10 as main components) and Q1 (which derived from Q2 and contained oligomers of DP5-DP8 with hexamer and a heptamer as the main components). The novel aspect of this work is the description of the effect of mixts. of oligosaccharides with different and known compn. on fungal growth rates. The growth rate of Alternaria alternata and Rhizopus stolonifer was initially inhibited by Q3 and Q2 at higher concns. Q1 had a growth stimulating effect on these two fungi. Growth of Botrytis cinerea was inhibited by Q3 and Q2, while Q1 had no effect on the growth of this fungus. Growth of Penicillium expansum was only slightly inhibited by higher concns. of sample Q3, while Q2 and Q1 had no effect. The inhibition of growth rates or their resistance toward chitooligosaccharides correlated with the absence or presence of chitinolytic enzymes in the culture media, resp. [on SciFinder (R)]
Y1  - 2008
UR  - http://www.springerlink.com/content/102966
SN  - 0301-486X
ER  - 
TY  - JOUR
A1  - Paz, Cristian
A1  - Peter, Martin G.
A1  - Schmidt, Bernd
A1  - Becerra, Jose
A1  - Gutierrez, Margarita
A1  - Astudillo, Luis
A1  - Silva, Mario
T1  - Synthesis and AChE inhibiting activity of 2, 4 substituted 6-Phenyl Pyrimidines
JF  - Journal of the Chilean Chemical Society
N2  - Novel substituted pyrimidines were synthesized from methyl 2,4-dioxo-4-phenyl-butanoate (I-A) and urea, followed by Mitsunobu coupling of I-A with benzyl or allyl alcohol to give the corresponding 2-hydroxypyrimidine ethers in good yields. Saponification of I-A, followed by reaction with benzyl or allyl amines in the presence of TBTU yielded 2-hydroxy-6-phenyl-pyrimidine 4-carboxamides. AChE and BuChE assays revealed 2-hydroxy-6-phenyl-pyrimidine-4-carboxyallyamide as the most active compound, IC50=90 mu M, with no inhibition of BuChE.
KW  - Pyrimidines
KW  - inhibition AChE
KW  - mitsunobu
KW  - TBTU
Y1  - 2012
SN  - 0717-9324
VL  - 57
IS  - 3
SP  - 1292
EP  - 1294
PB  - Sociedad Chilena De Quimica
CY  - Concepcion
ER  - 
TY  - JOUR
A1  - Peikow, Dirk
A1  - Matern, Christa-Maria
A1  - Peter, Martin G.
A1  - Schilde, Uwe
T1  - Crystal structure of (1,4,7,10,13-pentaoxacyclopentadecane-O,O ',O '',O ''')(trifluoromethanesulfonato-O,O ')sodium, Na(C10H20O5)(CF3SO3)
N2  - C11H20F3NaO8S, monoclinic, P121/nil (no. 11), a = 7.947(1) angstrom, b = 12.056(1) angstrom, c = 9.083(1) angstrom, P = 106.01 (1)degrees, V = 836.4 angstrom(3), Z = 2, R-gt(F) = 0.043, wR(ref)(F-2) = 0.120, T = 210 K.
Y1  - 2005
ER  - 
TY  - JOUR
A1  - Pereira, Fernanda S.
A1  - Nascimento, Heliara D. L.
A1  - Magalhaes, Alvicler
A1  - Peter, Martin G.
A1  - Bataglion, Giovana Anceski
A1  - Eberlin, Marcos N.
A1  - Gonzalez, Eduardo R. P.
T1  - ESI(+)-MS and GC-MS study of the hydrolysis of N-azobenzyl derivatives of chitosan
JF  - Molecules
N2  - New N-p-chloro-, N-p-bromo-, and N-p-nitrophenylazobenzylchitosan derivatives, as well as the corresponding azophenyl and azophenyl-p-sulfonic acids, were synthesized by coupling N-benzylvchitosan with aryl diazonium salts. The synthesized molecules were analyzed by UV-Vis, FT-IR, H-1-NMR and N-15-NMR spectroscopy. The capacity of copper chelation by these materials was studied by AAS. Chitosan and the derivatives were subjected to hydrolysis and the products were analyzed by ESI(+)-MS and GC-MS, confirming the formation of N-benzyl chitosan. Furthermore, the MS results indicate that a nucleophilic aromatic substitution (SnAr) reaction occurs under hydrolysis conditions, yielding chloroaniline from N-p-bromo-, and N-p-nitrophenylazo-benzylchitosan as well as bromoaniline from N-p-chloro-, and N-p-nitrophenylazobenzyl-chitosan.
KW  - chitosan
KW  - N-azobenzylchitosan
KW  - ESI-MS
KW  - GC-MS
KW  - SnAr reaction
Y1  - 2014
U6  - https://doi.org/10.3390/molecules191117604
SN  - 1420-3049
VL  - 19
IS  - 11
SP  - 17604
EP  - 17618
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Chitin and Chitosan from Animal Sources
N2  - A review on the chem. and biochem. of chitin and the chem. and application of chitosan. The following topics were discussed: structure of chitin and chitosan; occurrence and physiol. functions of chitin; detection of chitin in animals and anal. of chitin and chitosan; biosynthesis and biodegrdn. of chitin in animals; prodn. of chitin and chitosan; properties of chitin and chitosan; and applications of chitin and chitosan.
Y1  - 2002
SN  - 3-527-30227-1
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Chitin and Chitosan from Fungi
Y1  - 2002
SN  - 3-527-30227-1
ER  - 
TY  - GEN
A1  - Peter, Martin G.
T1  - Chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide
N2  - Chinone und Vorstufen, die oxidativ in Chinone und/oder Chinonmethide umgewandelt werden können, sind in der Natur weit verbreitet. Als sekundäre Naturstoffe wirken sie häufig antibiotisch, cytotoxisch, aber auch pathogen, und eine Reihe von Pflanzen und Tieren benutzt chinoide Substanzen als Abwehrstoffe, oft mit spektakulärem Erfolg. Auf makromolekularer Ebene spielen Chinonmethide im Pflanzenreich eine Schlüsselrolle bei der Biosynthese von Lignin, während die Bildung von Melanoproteinen ein Beispiel für Reaktionen von o-Chinonen im Tierreich ist. Bei den Insekten dienen Chinone und Chinonmethide zur Bildung des lebensnotwendigen Exoskeletts. Die Reaktivität von Chinonen in biologischen Systemen hat auch für den Menschen unmittelbare Bedeutung in pharmazeutischer, toxikologischer und technologischer Hinsicht. Den Beispielen in diesem Aufsatz liegt ein gemeinsames Prinzip zugrunde, nämlich die chemische Modifikation von Biopolymeren durch Chinone und Chinonmethide. Wie sich besonders bei einer detaillierteren Betrachtung der Reaktionen zeigt, die zur Sklerotisierung der Insektencuticula führen, sind in den letzten Jahren wichtige neue Erkenntnisse hinzugekommen, die vor allem durch die modernen Methoden der Stofftrennung und der Festkörper-NMR-Spektroskopie ermöglicht worden sind.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 043 
Y1  - 1989
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16802
ER  - 
TY  - GEN
A1  - Peter, Martin G.
T1  - Products of in vitro oxidation of N-acetyldopamine as possible components in the sclerotization of insect cuticle
N2  - [1-14C]-N-Acetyldopamine (NADA) was oxidized in the presence of methyl [3-3H]-β-alanate with mushroom tyrosinase. The complex mixture of reaction products was partly resolved by chromatographic procedures and analyzed by spectroscopic methods. Methyl-β-alanate is incorporated to only a small extent into oxidation products of NADA which inter alia are presumed to be oligomeric hydroxyquinones. After oxidation of [1-14C, 2-3H]-NADA with preparations from tanning Manduca sexta pupal cuticle, N-acetylnoradrenalin was identified as one of the products. Binding of radioactivity to melanin-like material was also observed. These results suggest that oxidation products different from those formulated usually for the crosslinkages between protein amino groups and N-acetyldopaquinone are deposited in darkly brown coloured insect cuticles during sclerotization.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 041 
KW  - N-acetyldopamine
KW  - sclerotization
KW  - tyrosinase; o-quinones
KW  - tanning agents
Y1  - 1980
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16759
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Applications and environmental aspects of chitin and chitosan
Y1  - 1995
SN  - 0022-233X
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - The Bio-organic chemistry of melanogenesis
Y1  - 1995
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Chemie i Biochemia Zewnetrznego Szkieletu Owadow : (Chemistry and biochemistry of the insect exoskeleton)
Y1  - 1995
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Chemistry and biochemistry of the insect exoskeleton
Y1  - 1995
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Chitin in den Startlöchern
Y1  - 1995
SN  - 0009-2959
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Natürliche Klebstoffe : von Muscheln, Seepocken, Spinnen und anderem Klebe-Getier
Y1  - 2001
SN  - 3-519-16195-8
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
T1  - Structures of Chitinases and the Design of Inhibitors
Y1  - 2001
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
A1  - Andersen, S. O.
T1  - The molecular architecture of the insect exoskeleton
Y1  - 1994
ER  - 
TY  - GEN
A1  - Peter, Martin G.
A1  - Andersen, Svend Olav
A1  - Hartmann, Rudolf
A1  - Miessner, Merle
A1  - Roepstorff, Peter
T1  - Catecholamine-protein conjugates : isolation of 4-phenylphenoxazin-2-ones from oxidative coupling of N-acetyldopamine with alipathic amino acids
N2  - 4-Phenylphenoxazinones were isolated after biomimetic oxidation, using diphenoloxidases of insect cuticle, mushroom tyrosinase, or after autoxidation of N-acetyldopamine (Image ) in the presence of β-alanine, β-alanine methyl ester or N-acetyl-L-lysine. They are formed presumably by addition of 2-aminoalkyl-5-alkylphenols to the o-quinone of biphenyltetrol which, in turn, arises from oxidative coupling of. The structures of present the first examples for the assembly of reasonably stable intermediates in the rather complex process of chemical modifications of aliphatic amino acid residues by o-quinones.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 062 
Y1  - 1992
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17571
ER  - 
TY  - GEN
A1  - Peter, Martin G.
A1  - Boldt, Peter C.
A1  - Niederstein, Yvonne
A1  - Peter-Katalinić, Jasna
T1  - Synthesen von Galactose-Cluster-haltigen Steroid-Derivaten
N2  - The synthesis of galactose clusters that are linked to a steroid moiety by a peptide-like spacer unit is described. The galactose cluster is obtained by Koenigs-Knorr glycosylation of TRIS-Gly-Fmoc (2b) under Helferich conditions. Peptide and ester bonds are formed after activation of carboxylic acids as diphenylthiophene dioxide (TDO) esters. 6a is synthesized in a convergent way by coupling of (Ac4Gal)3-TRIS-Gly (3e) with cholesteryl TDO succinate (5b). Coupling of (Ac4Gal)3-TRIS-Gly hydrogen succinate (3f) with Gly-O-Chol (5d) by means of EEDQ yields 6d. Reaction of (Ac4Gal)3-TRIS-Gly-SUCC-O-TDO (3g) with 25-hydroxycholesterol leads in a linear sequence to the oxysterol derivative 6f. Selective cleavage of the acetyl groups from galactose units yields the known compound 6b and the new derivatives 6e and 6g.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 042 
KW  - Glycoconjugates
KW  - Galactosides
KW  - Steroid esters
KW  - Amphiphiles
KW  - Glycopeptides
Y1  - 1990
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-16783
ER  - 
TY  - GEN
A1  - Peter, Martin G.
A1  - Förster, Hans
T1  - On the structure of Eumelanins : identification of constitutional patterns by solid-state NMR spectroscopy
N2  - Aus dem Inhalt: Melanins are complex polyphenolic polymers. They are usually formed in nature by enzyme-catalyzed oxidative polymerization of o-diphenols. The deep black eumelanins, derived from Dopa 1 or dopamine 3, are distinguished from the yellow to brown phaeomelanins obtained from Dopa in the presence of cysteine. Characteristic of eumelanins are the indole units, which are formed from catecholamines by intramolecular addition of the amino groups to the oxidatively generated o-quinones. [...]
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 053 
Y1  - 1989
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17027
ER  - 
TY  - GEN
A1  - Peter, Martin G.
A1  - Förster, Hans
T1  - Zur Struktur von Eumelaninen : Identifizierung von Konstitutionsmustern durch Festkörper-NMR-Spektroskopie
T1  - On the Structure of Eumelanins : Identification of Constitutional Patterns by Solid-state NMR Spectroscopy
N2  - Aus dem Inhalt: Melanine sind komplexe polyphenolische Polymere. In der Natur entstehen sie durch meist enzymkatalysierte oxidative Polymerisation von o-Diphenolen. Man unterscheidet die aus Dopa 1 oder Dopamin 3 hervorgehenden, tiefschwarzen Eumelanine von den aus Dopa in Gegenwart von Cystein entstehenden, gelben bis braunen Phaomelaninen. [...]
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 054 
Y1  - 1989
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-17038
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
A1  - Ley, J. P.
A1  - Petersen, Stefan
A1  - Londershausen, M.
A1  - Schumacher-Wandersleb, Michael H. M. G.
A1  - Spindler, Klaus-Dieter
A1  - Spindler-Barth, Margarethe
A1  - Turberg, Andreas
T1  - Synthesis of chitinase inhibitors
Y1  - 1994
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
A1  - Merz, A.
T1  - Stereoselective benzylic deprotonation in the enzymatic rearrangement of N-acetyldopamine derived o-Quinone to the p-Quinone methide
Y1  - 1995
SN  - 0957-4166
ER  - 
TY  - JOUR
A1  - Peter, Martin G.
A1  - Miessner, Merle
T1  - Primärstoffwechsel, Shikimat- und Phenylpropan-Gruppe, Vitamine, Coenzyme, Pflanzeninhaltsstoffe
Y1  - 1997
ER  -