TY  - JOUR
A1  - Li, Jian
A1  - Chen, You-Peng
A1  - Wang, Zi-Neng
A1  - Liu, Tie-Bin
A1  - Chen, Dan
A1  - Dong, Yun-Peng
A1  - Hocher, Berthold
T1  - A functional fetal HSD11B2[CA]n microsatellite polymorphism is associated with maternal serum cortisol concentrations in pregnant women
JF  - Kidney & blood pressure research : official organ of the Gesellschaft für Nephrologie
N2  - Background/Aims: Cortisol plays an important role during pregnancy. It controls maternal glucose metabolism and fetal development. Cortisol metabolism is partially controlled by the 11b-HSD2. This enzyme is expressed in the kidney and human placenta. The activity of the enzyme is partially controlled by functional polymorphisms: the HSD11B2[CA]n microsatellite polymorphism. The impact of this functional gene polymorphism on cortisol metabolism and potential effects on the newborn's is unknown so far. Methods: In the current prospective birth cohort study in southern Asia, we analyzed the association of the HSD11B2[CA]n microsatellite polymorphisms in 187 mothers and their newborn's on maternal and newborn's serum cortisol concentrations. Results: Using multivariable regression analyses considering known confounding ( gestational age, newborn's gender, the labor uterine contraction states and the timing during the day of blood taking), we showed that the fetal HSD11B2[CA]n microsatellite polymorphisms in the first intron was related to maternal cortisol concentration ( R2=0.26, B=96.27, p=0.007), whereas as the newborn's cortisol concentrations were independent of fetal and maternal HSD11B2[CA] n microsatellite polymorphism. Conclusions: Our study showed for the first time that the fetal HSD11B2[CA]n microsatellite polymorphism of the HSD11B2 gene in healthy uncomplicated human pregnancy is associated with maternal cortisol concentration. This indicates that fetal genes controlling cortisol metabolism may affect maternal cortisol concentration and hence physiology in healthy pregnant women.
KW  - Pregnancy
KW  - Placenta
KW  - Cortisol vertical bar metabolism
KW  - 11 beta-hydroxysteroid dehydrogenase 2
KW  - HSD11B2[CA]n polymorphism
Y1  - 2013
U6  - https://doi.org/10.1159/000355761
SN  - 1420-4096
SN  - 1423-0143
VL  - 38
IS  - 1
SP  - 132
EP  - 141
PB  - Karger
CY  - Basel
ER  - 
TY  - CHAP
A1  - Ohl, Sven
A1  - Brandt, S.
A1  - Kliegl, Reinhold
T1  - Immediate preparatory influences on microsaccades before saccade onset to endogenously vs. exogenously defined targets
T2  - Perception
Y1  - 2013
SN  - 0301-0066
SN  - 1468-4233
VL  - 42
IS  - 4
SP  - 37
EP  - 38
PB  - Sage Publ.
CY  - London
ER  - 
TY  - JOUR
A1  - Oberhänsli, Roland
A1  - Koralay, E.
A1  - Candan, Osman
A1  - Pourteau, Amaury
A1  - Bousquet, Romain
T1  - Late cretaceous eclogitic high-pressure relics in the Bitlis Massif
JF  - Geodinamica acta : revue de géologie dynamique et de géographie physique
N2  - A new occurrence of eclogites was found in the Kesandere valley in the eastern most part of the Bitlis complex, SE Anatolia. These high-pressure (HP) relics were preserved in calc-arenitic metasediments within the high-grade metamorphic basement of the Bitlis complex. The eclogitic parageneses were strongly overprinted during decompression and heating. These new eclogites locality complements the evidence of blueschist-facies metamorphism documented recently in the meta-sedimentary cover sequence of this part of the Bitlis complex. Thermodynamic calculations suggest peak conditions of ca. 480-540 degrees C/1.9-2.4GPa. New U/Pb dates of 84.4 +/-.9 and 82.4 +/-.9Ma were obtained on zircons from two Kesandere eclogite samples. On the basis of geochemical criteria, these dates are interpreted to represent zircon crystallization during the eclogitic peak stage. Kesandere eclogites differ from those previously described in the western Bitlis complex (Mt. Gablor locality) in terms of lithologic association, protolithic origin, and peak P-T conditions (600-650 degrees C/1.0-2.0GPa, respectively). On the other hand, eclogitic metamorphism of Kesandere metasediments occurred shortly before blueschist-facies metamorphism of the sedimentary cover (79-74Ma Ar-40/Ar-39 white mica). Therefore, the exhumation of Kesandere eclogites started between ca. 82 and 79Ma, while the meta-sedimentary cover was being buried. During this short time span, Kesandere eclogite were likely uplifted from similar to 65 to 35km depth, indicating a syn-subduction exhumation rate of similar to 4.3mm/a. Subsequently, eclogite- and blueschist-facies rocks were likely retrogressed contemporarily during collision-type metamorphism (around 72-69Ma). The Bitlis HP rocks thus sample a subduction zone that separated the Bitlis-Puturge (Bistun?) block from the South-Armenian block, further north. To the south, Eocene metasediments of the Urse formation are imbricated below the Bitlis complex. They contain (post Eocene) blueschists, testifying separation from the Arabian plate and southward migration of the subduction zone. The HT overprint of Kesandere eclogites can be related to the asthenospheric flow provoked by subducting slab retreat or break off.
KW  - eclogites
KW  - zircon
KW  - U
KW  - Pb ages
KW  - E Anatolia
KW  - subduction-collision
Y1  - 2013
U6  - https://doi.org/10.1080/09853111.2013.858951
SN  - 0985-3111
SN  - 1778-3593
VL  - 26
IS  - 3-4
SP  - 175
EP  - 190
PB  - Routledge, Taylor & Francis Group
CY  - Abingdon
ER  - 
TY  - JOUR
A1  - Vöth, Markus
A1  - Herbst, Uta
A1  - Liess, Frank
T1  - We know exactly what you want the development of a completely individualised conjoint analysis
JF  - International journal of market research
N2  - Improving the predictive validity of conjoint analysis has been an important research objective for many years. Whereas the majority of attempts have been different approaches to preference modelling, data collection or product presentation, only a few scholars have tried to improve predictive validity by individualising conjoint designs. This comes as a surprise because many markets have observed an augmented demand for customised products and highly heterogeneous customers' preferences. Against this background, the authors develop a conjoint variant based on a completely individualised conjoint design. More concretely, the new approach not only individualises the attributes, but also the attribute levels. The results of a comprehensive empirical study yield a significantly higher validity than existing standardised-level conjoint approaches. Consequently, they help marketers to gain deeper insights into their customers' preferences.
Y1  - 2013
U6  - https://doi.org/10.2501/IJMR-2013-038
SN  - 1470-7853
VL  - 55
IS  - 3
SP  - 437
EP  - 458
PB  - Market Research Society
CY  - London
ER  - 
TY  - JOUR
A1  - Basso, Heitor Cury
A1  - Qiu, Xunlin
A1  - Wirges, Werner
A1  - Gerhard, Reimund
T1  - Temporal evolution of the re-breakdown voltage in small gaps from nanoseconds to milliseconds
JF  - Applied physics letters
N2  - A detailed understanding of electric breakdown in dielectrics is of scientific and technological interest. In gaseous dielectrics, a so-called re-breakdown is sometimes observed after extinction of the previous discharge. Although time-dependent re-breakdown voltage is essentially known, its behavior immediately after the previous discharge is not precisely understood. We present an electronic circuit for accurate measurements of the time-dependent re-breakdown voltage in small gaps from tens of nanoseconds to several milliseconds after the previous spark. Results from such experiments are compared with earlier findings, and relevant physical mechanisms such as heating of the gas, decay of the plasma, and ionization of excited atoms and molecules are discussed. It is confirmed that the thermal model is not valid at times below several microseconds.
Y1  - 2013
U6  - https://doi.org/10.1063/1.4773518
SN  - 0003-6951
VL  - 102
IS  - 1
PB  - American Institute of Physics
CY  - Melville
ER  - 
TY  - JOUR
A1  - Schulz, Johannes H. P.
A1  - Barkai, Eli
A1  - Metzler, Ralf
T1  - Aging effects and population splitting in single-particle trajectoryaverages
JF  - Physical review letters
N2  - We study time averages of single particle trajectories in scale-free anomalous diffusion processes, in which the measurement starts at some time t(a) > 0 after initiation of the process at t = 0. Using aging renewal theory, we show that for such nonstationary processes a large class of observables are affected by a unique aging function, which is independent of boundary conditions or the external forces. Moreover, we discuss the implications of aging induced population splitting: with growing age ta of the process, an increasing fraction of particles remains motionless in a measurement of fixed duration. Consequences for single biomolecule tracking in live cells are discussed.
Y1  - 2013
U6  - https://doi.org/10.1103/PhysRevLett.110.020602
SN  - 0031-9007
SN  - 1079-7114
VL  - 110
IS  - 2
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - von der Lippe, Moritz
A1  - Bullock, James M.
A1  - Kowarik, Ingo
A1  - Knopp, Tatjana
A1  - Wichmann, Matthias
T1  - Human-mediated dispersal of seeds by the airflow of vehicles
JF  - PLoS one
N2  - Human-mediated dispersal is known as an important driver of long-distance dispersal for plants but underlying mechanisms have rarely been assessed. Road corridors function as routes of secondary dispersal for many plant species but the extent to which vehicles support this process remains unclear. In this paper we quantify dispersal distances and seed deposition of plant species moved over the ground by the slipstream of passing cars. We exposed marked seeds of four species on a section of road and drove a car along the road at a speed of 48 km/h. By tracking seeds we quantified movement parallel as well as lateral to the road, resulting dispersal kernels, and the effect of repeated vehicle passes. Median distances travelled by seeds along the road were about eight meters for species with wind dispersal morphologies and one meter for species without such adaptations. Airflow created by the car lifted seeds and resulted in longitudinal dispersal. Single seeds reached our maximum measuring distance of 45 m and for some species exceeded distances under primary dispersal. Mathematical models were fit to dispersal kernels. The incremental effect of passing vehicles on longitudinal dispersal decreased with increasing number of passes as seeds accumulated at road verges. We conclude that dispersal by vehicle airflow facilitates seed movement along roads and accumulation of seeds in roadside habitats. Dispersal by vehicle airflow can aid the spread of plant species and thus has wide implications for roadside ecology, invasion biology and nature conservation.
Y1  - 2013
U6  - https://doi.org/10.1371/journal.pone.0052733
SN  - 1932-6203
VL  - 8
IS  - 1
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - JOUR
A1  - Arlen, T.
A1  - Aune, T.
A1  - Beilicke, M.
A1  - Benbow, W.
A1  - Bouvier, A.
A1  - Buckley, J. H.
A1  - Bugaev, V.
A1  - Cesarini, A.
A1  - Ciupik, L.
A1  - Connolly, M. P.
A1  - Cui, W.
A1  - Dickherber, R.
A1  - Dumm, J.
A1  - Errando, M.
A1  - Falcone, A.
A1  - Federici, S.
A1  - Feng, Q.
A1  - Finley, J. P.
A1  - Finnegan, G.
A1  - Fortson, L.
A1  - Furniss, A.
A1  - Galante, N.
A1  - Gall, D.
A1  - Griffin, S.
A1  - Grube, J.
A1  - Gyuk, G.
A1  - Hanna, D.
A1  - Holder, J.
A1  - Humensky, T. B.
A1  - Kaaret, P.
A1  - Karlsson, N.
A1  - Kertzman, M.
A1  - Khassen, Y.
A1  - Kieda, D.
A1  - Krawczynski, H.
A1  - Krennrich, F.
A1  - Maier, G.
A1  - Moriarty, P.
A1  - Mukherjee, R.
A1  - Nelson, T.
A1  - de Bhroithe, A. O'Faolain
A1  - Ong, R. A.
A1  - Orr, M.
A1  - Park, N.
A1  - Perkins, J. S.
A1  - Pichel, A.
A1  - Pohl, Martin
A1  - Prokoph, H.
A1  - Quinn, J.
A1  - Ragan, K.
A1  - Reyes, L. C.
A1  - Reynolds, P. T.
A1  - Roache, E.
A1  - Saxon, D. B.
A1  - Schroedter, M.
A1  - Sembroski, G. H.
A1  - Staszak, D.
A1  - Telezhinsky, Igor O.
A1  - Tesic, G.
A1  - Theiling, M.
A1  - Tsurusaki, K.
A1  - Varlotta, A.
A1  - Vincent, S.
A1  - Wakely, S. P.
A1  - Weekes, T. C.
A1  - Weinstein, A.
A1  - Welsing, R.
A1  - Williams, D. A.
A1  - Zitzer, B.
A1  - Jorstad, S. G.
A1  - MacDonald, N. R.
A1  - Marscher, A. P.
A1  - Smith, P. S.
A1  - Walker, R. C.
A1  - Hovatta, T.
A1  - Richards, J.
A1  - Max-Moerbeck, W.
A1  - Readhead, A.
A1  - Lister, M. L.
A1  - Kovalev, Y. Y.
A1  - Pushkarev, A. B.
A1  - Gurwell, M. A.
A1  - Lahteenmaki, A.
A1  - Nieppola, E.
A1  - Tornikoski, M.
A1  - Jarvela, E.
T1  - Rapid TeV Gamma-Ray flaring of bl lacertae
JF  - The astrophysical journal : an international review of spectroscopy and astronomical physics
N2  - We report on the detection of a very rapid TeV gamma-ray flare from BL Lacertae on 2011 June 28 with the Very Energetic Radiation Imaging Telescope Array System (VERITAS). The flaring activity was observed during a 34.6 minute exposure, when the integral flux above 200 GeV reached (3.4 +/- 0.6) x 10(-6) photons m(-2) s(-1), roughly 125% of the Crab Nebula flux measured by VERITAS. The light curve indicates that the observations missed the rising phase of the flare but covered a significant portion of the decaying phase. The exponential decay time was determined to be 13 +/- 4 minutes, making it one of the most rapid gamma-ray flares seen from a TeV blazar. The gamma-ray spectrum of BL Lacertae during the flare was soft, with a photon index of 3.6 +/- 0.4, which is in agreement with the measurement made previously by MAGIC in a lower flaring state. Contemporaneous radio observations of the source with the Very Long Baseline Array revealed the emergence of a new, superluminal component from the core around the time of the TeV gamma-ray flare, accompanied by changes in the optical polarization angle. Changes in flux also appear to have occurred at optical, UV, and GeV gamma-ray wavelengths at the time of the flare, although they are difficult to quantify precisely due to sparse coverage. A strong flare was seen at radio wavelengths roughly four months later, which might be related to the gamma-ray flaring activities. We discuss the implications of these multiwavelength results.
KW  - galaxies: active
KW  - galaxies: individual (BL Lacertae, VER J2202+422)
KW  - gamma rays: galaxies
Y1  - 2013
U6  - https://doi.org/10.1088/0004-637X/762/2/92
SN  - 0004-637X
VL  - 762
IS  - 2
PB  - IOP Publ. Ltd.
CY  - Bristol
ER  - 
TY  - JOUR
A1  - Godec, Aljaz
A1  - Metzler, Ralf
T1  - Finite-Time effects and ultraweak ergodicity breaking in superdiffusive dynamics
JF  - Physical review letters
N2  - We study the ergodic properties of superdiffusive, spatiotemporally coupled Levy walk processes. For trajectories of finite duration, we reveal a distinct scatter of the scaling exponents of the time averaged mean squared displacement (delta x(2)) over bar around the ensemble value 3 - alpha (1 < alpha < 2) ranging from ballistic motion to subdiffusion, in strong contrast to the behavior of subdiffusive processes. In addition we find a significant dependence of the average of (delta x(2)) over bar over an ensemble of trajectories as a function of the finite measurement time. This so-called finite-time amplitude depression and the scatter of the scaling exponent is vital in the quantitative evaluation of superdiffusive processes. Comparing the long time average of the second moment with the ensemble mean squared displacement, these only differ by a constant factor, an ultraweak ergodicity breaking.
Y1  - 2013
U6  - https://doi.org/10.1103/PhysRevLett.110.020603
SN  - 0031-9007
VL  - 110
IS  - 2
PB  - American Physical Society
CY  - College Park
ER  - 
TY  - JOUR
A1  - Liu, Chun
A1  - Sibly, Richard M.
A1  - Grimm, Volker
A1  - Thorbek, Pernille
T1  - Linking pesticide exposure and spatial dynamics an individual-based model of wood mouse (Apodemus sylvaticus) populations in agricultural landscapes
JF  - Ecological modelling : international journal on ecological modelling and engineering and systems ecolog
N2  - The wood mouse is a common and abundant species in agricultural landscape and is a focal species in pesticide risk assessment. Empirical studies on the ecology of the wood mouse have provided sufficient information for the species to be modelled mechanistically. An individual-based model was constructed to explicitly represent the locations and movement patterns of individual mice. This together with the schedule of pesticide application allows prediction of the risk to the population from pesticide exposure. The model included life-history traits of wood mice as well as typical landscape dynamics in agricultural farmland in the UK. The model obtains a good fit to the available population data and is fit for risk assessment purposes. It can help identify spatio-temporal situations with the largest potential risk of exposure and enables extrapolation from individual-level endpoints to population-level effects. Largest risk of exposure to pesticides was found when good crop growth in the "sink" fields coincided with high "source" population densities in the hedgerows.
KW  - Population dynamics
KW  - Pesticides
KW  - Ecological risk assessment
KW  - Habitat choice
KW  - Agent-based model
KW  - NetLogo
Y1  - 2013
U6  - https://doi.org/10.1016/j.ecolmodel.2012.09.016
SN  - 0304-3800
VL  - 248
IS  - 2
SP  - 92
EP  - 102
PB  - Elsevier
CY  - Amsterdam
ER  -