TY  - JOUR
A1  - Glatzel, Stefan
A1  - Laschewsky, André
A1  - Lutz, Jean-Francois
T1  - Well-Defined uncharged polymers with a sharp UCST in water and in physiological milieu
JF  - Macromolecules : a publication of the American Chemical Society
Y1  - 2011
U6  - https://doi.org/10.1021/ma102677k
SN  - 0024-9297
VL  - 44
IS  - 2
SP  - 413
EP  - 415
PB  - American Chemical Society
CY  - Washington
ER  - 
TY  - JOUR
A1  - Buller, Jens
A1  - Laschewsky, André
A1  - Lutz, Jean-Francois
A1  - Wischerhoff, Erik
T1  - Tuning the lower critical solution temperature of thermoresponsive polymers by biospecific recognition
JF  - Polymer Chemistry
N2  - A thermosensitive statistical copolymer based on oligo(ethylene glycol) methacrylates incorporating biotin was synthesized by free radical copolymerisation. The influence of added avidin on its thermoresponsive behaviour was investigated. The specific binding of avidin to the biotinylated copolymers provoked a marked increase of the lower critical solution temperature.
Y1  - 2011
U6  - https://doi.org/10.1039/c1py00001b
SN  - 1759-9954
VL  - 2
IS  - 7
SP  - 1486
EP  - 1489
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Zehm, Daniel
A1  - Laschewsky, André
A1  - Heunemann, Peggy
A1  - Gradzielski, Michael
A1  - Prevost, Sylvain
A1  - Liang, Hua
A1  - Rabe, Jürgen P.
A1  - Lutz, Jean-Francois
T1  - Synthesis and self-assembly of amphiphilic semi-brush and dual brush block copolymers in solution and on surfaces
JF  - Polymer Chemistry
N2  - The combination of two techniques of controlled free radical polymerization, namely the reversible addition fragmentation chain transfer (RAFT) and the atom transfer radical polymerization (ATRP) techniques, together with the use of a macromonomer allowed the synthesis of symmetrical triblock copolymers, designed as amphiphilic dual brushes. One type of brush was made of poly(n-butyl acrylate) as soft hydrophobic block, i.e. characterized by a low glass transition temperature, while the other one was made of hydrophilic poly(ethylene glycol) (PEG). The new triblock polymers represent "giant surfactants" according to their molecular architecture. The hydrophobic and hydrophilic blocks microphase separate in the bulk. In aqueous solution, they aggregate into globular micellar aggregates, their size being determined by the length of the stretched polymer molecules. As determined by the combination of various scattering techniques for the dual brush copolymer, a rather compact structure is formed, which is dominated by the large hydrophobic poly(n-butyl acrylate) block. The aggregation number for the dual brush is about 10 times larger than for the "semi-brush" precursor copolymer, due to the packing requirements for the much bulkier hydrophobic core. On mica surfaces the triblock copolymers adsorb with worm-like backbones and stretched out side chains.
Y1  - 2011
U6  - https://doi.org/10.1039/c0py00200c
SN  - 1759-9954
VL  - 2
IS  - 1
SP  - 137
EP  - 147
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  - 
TY  - JOUR
A1  - Wischerhoff, Erik
A1  - Badi, Nezha
A1  - Laschewsky, André
A1  - Lutz, Jean-Francois
ED  - Börner, Hans Gerhard
ED  - Lutz, JF
T1  - Smart polymer surfaces concepts and applications in biosciences
JF  - Advances in polymer science = Fortschritte der Hochpolymeren-Forschung
JF  - Advances in Polymer Science
N2  - Stimuli-responsive macromolecules (i.e., pH-, thermo-, photo-, chemo-, and bioresponsive polymers) have gained exponential importance in materials science, nanotechnology, and biotechnology during the last two decades. This chapter describes the usefulness of this class of polymer for preparing smart surfaces (e.g., modified planar surfaces, particles surfaces, and surfaces of three-dimensional scaffolds). Some efficient pathways for connecting these macromolecules to inorganic, polymer, or biological substrates are described. In addition, some emerging bioapplications of smart polymer surfaces (e.g., antifouling surfaces, cell engineering, protein chromatography, tissue engineering, biochips, and bioassays) are critically discussed.
KW  - Antifouling surfaces
KW  - Bioactive surfaces
KW  - Biocompatible polymers
KW  - Bioseparation
KW  - Cell engineering
KW  - Polymer-modified surfaces
KW  - Stimuli-responsive polymers
Y1  - 2011
SN  - 978-3-642-20154-7
U6  - https://doi.org/10.1007/12_2010_88
SN  - 0065-3195
VL  - 240
IS  - 1
SP  - 1
EP  - 33
PB  - Springer
CY  - Berlin
ER  -