TY - JOUR A1 - Smieliauskas, Wally A1 - Bewley, Kathryn A1 - Gronewold, Ulfert A1 - Menzefricke, Ulrich T1 - Misleading Forecasts in Accounting Estimates BT - a Form of Ethical Blindness in Accounting Standards? JF - Journal of business ethics N2 - The current financial reporting environment, with its increasing use of accounting estimates, including fair value estimates, suggests that unethical accounting estimates may be a growing concern. This paper provides explanations and empirical evidence for why some types of accounting estimates in financial reporting may promote a form of ethical blindness. These types of ethical blindness can have an escalating effect that corrupts not only an individual or organization but also the accounting profession and the public interest it serves. Ethical blindness in the standards of professional accountants may be a factor in the extent of misreporting, and may have taken on new urgency as a result of the proposals to change the conceptual framework for financial reporting using international standards. The social consequences for users of financial statements can be huge. The acquittal of former Nortel executives on fraud charges related to accounting manipulations is viewed by many as legitimizing accounting gamesmanship. This decision illustrates that the courts may not be the best place to deal with ethical reporting issues. The courts may be relied on for only the most egregious unethical conduct and, even then, the accounting profession is ill equipped to assist the legal system in prosecuting accounting fraud unless the standards have been clarified. We argue that the problem of unethical reporting should be addressed by the accounting profession itself, preferably as a key part of the conceptual framework that supports accounting and auditing standards, and the codes of ethical conduct that underpin the professionalism of accountants. KW - Ethical accounting estimates KW - Estimation uncertainty KW - IASB accounting conceptual framework KW - Accounting standards KW - Auditing standards Y1 - 2016 U6 - https://doi.org/10.1007/s10551-016-3289-1 SN - 0167-4544 SN - 1573-0697 VL - 152 IS - 2 SP - 437 EP - 457 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Möring, Sebastian A1 - Leino, Olli Tapio T1 - Beyond games as political education BT - Neo-liberalism in the contemporary computer game form JF - Journal of Gaming & Virtual Worlds N2 - This article introduces the juxtaposed notions of liberal and neo-liberal gameplay in order to show that, while forms of contemporary game culture are heavily influenced by neo-liberalism, they often appear under a liberal disguise. The argument is grounded in Claus Pias’ idea of games as always a product of their time in terms of economic, political and cultural history. The article shows that romantic play theories (e.g. Schiller, Huizinga and Caillois) are circling around the notion of play as ‘free’, which emerged in parallel with the philosophy of liberalism and respective socio-economic developments such as the industrialization and the rise of the nation state. It shows further that contemporary discourse in computer game studies addresses computer game/play as if it still was the romantic form of play rooted in the paradigm of liberalism. The article holds that an account that acknowledges the neo-liberalist underpinnings of computer games is more suited to addressing contemporary computer games, among which are phenomena such as free to play games, which repeat the structures of a neo-liberal society. In those games the players invest time and effort in developing their skills, although their future value is mainly speculative – just like this is the case for citizens of neo-liberal societies. Y1 - 2016 U6 - https://doi.org/10.1386/jgvw.8.2.145_1 SN - 1757-191X VL - 8 IS - 2 SP - 145 EP - 161 PB - Intellect CY - Bristol ER - TY - JOUR A1 - Trautwein, Matthias A1 - Fredriksson, Kai A1 - Möller, Heiko Michael A1 - Exner, Thomas E. T1 - Automated assignment of NMR chemical shifts based on a known structure and 4D spectra JF - Journal of biomolecular NMR N2 - Apart from their central role during 3D structure determination of proteins the backbone chemical shift assignment is the basis for a number of applications, like chemical shift perturbation mapping and studies on the dynamics of proteins. This assignment is not a trivial task even if a 3D protein structure is known and needs almost as much effort as the assignment for structure prediction if performed manually. We present here a new algorithm based solely on 4D [H-1, N-15]-HSQC-NOESY-[H-1, N-15]-HSQC spectra which is able to assign a large percentage of chemical shifts (73-82 %) unambiguously, demonstrated with proteins up to a size of 250 residues. For the remaining residues, a small number of possible assignments is filtered out. This is done by comparing distances in the 3D structure to restraints obtained from the peak volumes in the 4D spectrum. Using dead-end elimination, assignments are removed in which at least one of the restraints is violated. Including additional information from chemical shift predictions, a complete unambiguous assignment was obtained for Ubiquitin and 95 % of the residues were correctly assigned in the 251 residue-long N-terminal domain of enzyme I. The program including source code is available at https://github.com/thomasexner/4Dassign. KW - Chemical shift assignment KW - Protein KW - 3D structure KW - 4D NOESY Y1 - 2016 U6 - https://doi.org/10.1007/s10858-016-0050-0 SN - 0925-2738 SN - 1573-5001 VL - 65 SP - 217 EP - 236 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Maier, Stefan K. A1 - Poluektov, Georgiy A1 - Jester, Stefan-S. A1 - Möller, Heiko Michael A1 - Hoeger, Sigurd T1 - Fast Oxidative Cyclooligomerization towards Low- and High-Symmetry Thiophene Macrocycles JF - Chemistry - a European journal N2 - Macrocycles with quaterthiophene subunits were obtained by cyclooligomerization by direct oxidative coupling of unsubstituted dithiophene moieties. The rings were closed with high selectivity by an α,β′-connection of the thiophenes as proven by NMR spectroscopy. The reaction of the precursor with terthiophene moieties yielded the symmetric α,α′-linked macrocycle in low yield together with various differently connected isomers. Blocking of the β-position of the half-rings yielded selectively the α,α′-linked macrocycle. Selected cyclothiophenes were investigated by scanning tunneling microscopy, which displayed the formation of highly ordered 2D crystalline monolayers. KW - cyclooligomers KW - scanning tunneling microscopy KW - self-assembled monolayers KW - shape-persistent macrocycles KW - thiophenes Y1 - 2016 U6 - https://doi.org/10.1002/chem.201503211 SN - 0947-6539 SN - 1521-3765 VL - 22 SP - 1379 EP - 1384 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Prestel, Andreas A1 - Möller, Heiko Michael T1 - Spatio-temporal control of cellular uptake achieved by photoswitchable cell-penetrating peptides JF - Chemical communications N2 - The selective uptake of compounds into specific cells of interest is a major objective in cell biology and drug delivery. By incorporation of a novel, thermostable azobenzene moiety we generated peptides that can be switched optically between an inactive state and an active, cell-penetrating state with excellent spatio-temporal control. Y1 - 2016 U6 - https://doi.org/10.1039/c5cc06848g SN - 1359-7345 SN - 1364-548X VL - 52 SP - 701 EP - 704 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Holert, Johannes A1 - Yücel, Onur A1 - Jagmann, Nina A1 - Prestel, Andreas A1 - Möller, Heiko Michael A1 - Philipp, Bodo T1 - Identification of bypass reactions leading to the formation of one central steroid degradation intermediate in metabolism of different bile salts in Pseudomonas sp strain Chol1 JF - Environmental microbiology Y1 - 2016 U6 - https://doi.org/10.1111/1462-2920.13192 SN - 1462-2912 SN - 1462-2920 VL - 18 SP - 3373 EP - 3389 PB - Wiley-Blackwell CY - Hoboken ER - TY - THES A1 - Böhm, Verónica Julia T1 - La imperfectividad en la prensa española y su relación con las categorías semánticas de modalidad y evidencialidad T2 - Potsdam Linguistic Investigations / Potsdamer Linguistische Untersuchungen / Recherches Linguistiques à Potsdam ; 19 N2 - Este libro adopta un enfoque semántico-funcional en el estudio de la imperfectividad en el español. La imperfectividad, como categoría semántico-funcional, encuentra afinidades con otras funciones semánticas, donde el valor de verdad de una situación se presenta como indeterminado o impreciso como, por ejemplo, en la reproducción de citas y distanciamiento del hablante frente a lo dicho; de manera que la imperfectividad se solapa con la modalidad y evidencialidad. Asimismo, se analizan las funciones secundarias de la imperfectividad relacionadas con la modalidad epistémica y evidencialidad indirecta en la prensa española. En todos los casos, los textos analizados proceden de corpus reales del español (CREA, Corpus del Español y GlossaNet). Y1 - 2016 SN - 978-3-631-66776-7 PB - Lang CY - Frankfurt am Main ER - TY - JOUR A1 - Stolle, Claudia A1 - Michaelis, Ingo A1 - Rauberg, Jan T1 - The role of high-resolution geomagnetic field models for investigating ionospheric currents at low Earth orbit satellites JF - Earth, planets and space N2 - Low Earth orbiting geomagnetic satellite missions, such as the Swarm satellite mission, are the only means to monitor and investigate ionospheric currents on a global scale and to make in situ measurements of F region currents. High-precision geomagnetic satellite missions are also able to detect ionospheric currents during quiet-time geomagnetic conditions that only have few nanotesla amplitudes in the magnetic field. An efficient method to isolate the ionospheric signals from satellite magnetic field measurements has been the use of residuals between the observations and predictions from empirical geomagnetic models for other geomagnetic sources, such as the core and lithospheric field or signals from the quiet-time magnetospheric currents. This study aims at highlighting the importance of high-resolution magnetic field models that are able to predict the lithospheric field and that consider the quiet-time magnetosphere for reliably isolating signatures from ionospheric currents during geomagnetically quiet times. The effects on the detection of ionospheric currents arising from neglecting the lithospheric and magnetospheric sources are discussed on the example of four Swarm orbits during very quiet times. The respective orbits show a broad range of typical scenarios, such as strong and weak ionospheric signal (during day- and nighttime, respectively) superimposed over strong and weak lithospheric signals. If predictions from the lithosphere or magnetosphere are not properly considered, the amplitude of the ionospheric currents, such as the midlatitude Sq currents or the equatorial electrojet (EEJ), is modulated by 10-15 % in the examples shown. An analysis from several orbits above the African sector, where the lithospheric field is significant, showed that the peak value of the signatures of the EEJ is in error by 5 % in average when lithospheric contributions are not considered, which is in the range of uncertainties of present empirical models of the EEJ. KW - Geomagnetic field KW - Ionospheric current KW - Geomagnetic models Y1 - 2016 U6 - https://doi.org/10.1186/s40623-016-0494-1 SN - 1880-5981 VL - 68 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Denecke, Klaus-Dieter T1 - The partial clone of linear terms JF - Siberian Mathematical Journal N2 - Generalizing a linear expression over a vector space, we call a term of an arbitrary type tau linear if its every variable occurs only once. Instead of the usual superposition of terms and of the total many-sorted clone of all terms in the case of linear terms, we define the partial many-sorted superposition operation and the partial many-sorted clone that satisfies the superassociative law as weak identity. The extensions of linear hypersubstitutions are weak endomorphisms of this partial clone. For a variety V of one-sorted total algebras of type tau, we define the partial many-sorted linear clone of V as the partial quotient algebra of the partial many-sorted clone of all linear terms by the set of all linear identities of V. We prove then that weak identities of this clone correspond to linear hyperidentities of V. KW - linear term KW - clone KW - partial clone KW - linear hypersubstitution KW - linear identity KW - linear hyperidentity Y1 - 2016 U6 - https://doi.org/10.1134/S0037446616040030 SN - 0037-4466 SN - 1573-9260 VL - 57 SP - 589 EP - 598 PB - Pleiades Publ. CY - New York ER - TY - CHAP A1 - Kiy, Alexander A1 - Hafer, Jörg A1 - Schumann, Marlen A1 - Enke, Uta ED - Lucke, Ulrike ED - Schwill, Andreas ED - Zender, Raphael T1 - Digitale Teilnehmerzertifikate und Open Badges verbinden BT - Der E-Teaching-Badge T2 - DeLFI 2016 - Die 14. E-Learning Fachtagung Informatik 11.-14. September 2016 Potsdam N2 - Während Qualifikationen und Kompetenzen, die auf informellem Wege erworben werden, immer mehr Beachtung finden, stellt sowohl deren Darstellung als auch die Anerkennung ein meist unüberwindbares Hindernis für Ausstellende und Erwerbende dar. Vermehrt wird unterdessen von klassisch papiergebundenen auf digitale Teilnahmezertifikate umgestellt, um den Nachweis von Kompetenz- und Qualifikationserwerb zu vereinfachen. In diesem Zusammenhang kann die Verbindung von digitalen Teilnahmezertifikaten und Open Badges einen Mehrwert für die öffentliche Darstellung und Verifikation bieten. KW - Teilnehmerzertifikate KW - Peer-Review KW - Open Badges KW - Open Badge Infrastructure KW - OBI Y1 - 2016 UR - http://subs.emis.de/LNI/Proceedings/Proceedings262/article21.html SN - 978-3-88579-656-5 IS - P-262 SP - 285 EP - 287 PB - Gesellschaft für Informatik CY - Bonn ER - TY - JOUR A1 - Leib, Julia T1 - Shaping peace: an investigation of the mechanisms underlying post-conflict peacebuilding JF - Peace, conflict & development : an interdisciplinary journal N2 - What shapes peace, and how can peace be successfully built in those countries affected by armed conflict? This paper examines mpeacebuilding in the aftermath of civil wars in order to identify the conditions for post-conflict peace. The field of civil war research is characterised by case studies, comparative analyses and quantitative research, which relate relatively little to each other. Furthermore, the complex dynamics of peacebuilding have hardly been investigated so far. Thus, the question remains of how best to enhance the prospects of a stable peace in post-conflict societies. Therefore, it is necessary to capture the dynamics of post-conflict peace. This paper aims at helping to narrow these research gaps by 1) presenting the benefits of set theoretic methods for peace and conflict studies; 2) identifying remote conflict environment factors and proximate peacebuilding factors which have an influence on the peacebuilding process and 3) proposing a set-theoretic multi-method research approach in order to identify the causal structures and mechanisms underlying the complex realm of post-conflict peacebuilding. By implementing this transparent and systematic comparative approach, it will become possible to discover the dynamics of post-conflict peace. KW - civil war KW - peacebuilding KW - post-conflict peace KW - set theory KW - QCA Y1 - 2016 SN - 1742-0601 IS - 22 SP - 25 EP - 76 PB - Univ. CY - Bradford ER - TY - JOUR A1 - Abseher, Michael A1 - Musliu, Nysret A1 - Woltran, Stefan A1 - Gebser, Martin A1 - Schaub, Torsten H. T1 - Shift Design with Answer Set Programming JF - Fundamenta informaticae N2 - Answer Set Programming (ASP) is a powerful declarative programming paradigm that has been successfully applied to many different domains. Recently, ASP has also proved successful for hard optimization problems like course timetabling and travel allotment. In this paper, we approach another important task, namely, the shift design problem, aiming at an alignment of a minimum number of shifts in order to meet required numbers of employees (which typically vary for different time periods) in such a way that over- and understaffing is minimized. We provide an ASP encoding of the shift design problem, which, to the best of our knowledge, has not been addressed by ASP yet. Our experimental results demonstrate that ASP is capable of improving the best known solutions to some benchmark problems. Other instances remain challenging and make the shift design problem an interesting benchmark for ASP-based optimization methods. Y1 - 2016 U6 - https://doi.org/10.3233/FI-2016-1396 SN - 0169-2968 SN - 1875-8681 VL - 147 SP - 1 EP - 25 PB - IOS Press CY - Amsterdam ER - TY - JOUR A1 - Vorburger, Thomas A1 - Nedielkov, Ruslan A1 - Brosig, Alexander A1 - Bok, Eva A1 - Schunke, Emina A1 - Steffen, Wojtek A1 - Mayer, Sonja A1 - Goetz, Friedrich A1 - Möller, Heiko Michael A1 - Steuber, Julia T1 - Role of the Na+-translocating NADH:quinone oxidoreductase in voltage generation and Na+ extrusion in Vibrio cholerae JF - Biochimica et biophysica acta : Bioenergetics N2 - For Vibrio cholerae, the coordinated import and export of Na+ is crucial for adaptation to habitats with different osmolarities. We investigated the Na+-extruding branch of the sodium cycle in this human pathogen by in vivo Na-23-NMR spectroscopy. The Na+ extrusion activity of cells was monitored after adding glucose which stimulated respiration via the Na+-translocating NADH:quinone oxidoreductase (Na+-NQR). In a V. cholerae deletion mutant devoid of the Na+-NQR encoding genes (nqrA-F), rates of respiratory Na+ extrusion were decreased by a factor of four, but the cytoplasmic Na+ concentration was essentially unchanged. Furthermore, the mutant was impaired in formation of transmembrane voltage (Delta psi, inside negative) and did not grow under hypoosmotic conditions at pH 8.2 or above. This growth defect could be complemented by transformation with the plasmid encoded nqr operon. In an alkaline environment, Na+/H+ antiporters acidify the cytoplasm at the expense of the transmembrane voltage. It is proposed that, at alkaline pH and limiting Na+ concentrations, the Na+-NQR is crucial for generation of a transmembrane voltage to drive the import of H+ by electrogenic Na+/H+ antiporters. Our study provides the basis to understand the role of the Na+-NQR in pathogenicity of V. cholerae and other pathogens relying on this primary Na+ pump for respiration. (C) 2015 Elsevier B.V. All rights reserved. KW - Nuclear magnetic resonance (NMR) KW - Sodium transport KW - Vibrio cholerae KW - Respiration KW - Na+ homeostasis KW - Hypoosmotic stress Y1 - 2016 U6 - https://doi.org/10.1016/j.bbabio.2015.12.010 SN - 0005-2728 SN - 0006-3002 VL - 1857 SP - 473 EP - 482 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Kistner, Saskia A1 - Vollmeyer, Regina A1 - Burns, Bruce D. A1 - Kortenkamp, Ulrich T1 - Model development in scientific discovery learning with a computer-based physics task JF - Computers in human behavior N2 - Based on theories of scientific discovery learning (SDL) and conceptual change, this study explores students' preconceptions in the domain of torques in physics and the development of these conceptions while learning with a computer-based SDL task. As a framework we used a three-space theory of SDL and focused on model space, which is supposed to contain the current conceptualization/model of the learning domain, and on its change through hypothesis testing and experimenting. Three questions were addressed: (1) What are students' preconceptions of torques before learning about this domain? To do this a multiple-choice test for assessing students' models of torques was developed and given to secondary school students (N = 47) who learned about torques using computer simulations. (2) How do students' models of torques develop during SDL? Working with simulations led to replacement of some misconceptions with physically correct conceptions. (3) Are there differential patterns of model development and if so, how do they relate to students’ use of the simulations? By analyzing individual differences in model development, we found that an intensive use of the simulations was associated with the acquisition of correct conceptions. Thus, the three-space theory provided a useful framework for understanding conceptual change in SDL. KW - Scientific discovery learning KW - Multiple problem spaces KW - Computer simulations KW - Physics concepts KW - Misconceptions KW - Conceptual change Y1 - 2016 U6 - https://doi.org/10.1016/j.chb.2016.02.041 SN - 0747-5632 SN - 1873-7692 VL - 59 SP - 446 EP - 455 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Sinclair, Nathalie A1 - Bussi, Maria G. Bartolini A1 - de Villiers, Michael A1 - Jones, Keith A1 - Kortenkamp, Ulrich A1 - Leung, Allen A1 - Owens, Kay T1 - Recent research on geometry education: an ICME-13 survey team report JF - ZDM : The International Journal on Mathematics Education N2 - This survey on the theme of Geometry Education (including new technologies) focuses chiefly on the time span since 2008. Based on our review of the research literature published during this time span (in refereed journal articles, conference proceedings and edited books), we have jointly identified seven major threads of contributions that span from the early years of learning (pre-school and primary school) through to post-compulsory education and to the issue of mathematics teacher education for geometry. These threads are as follows: developments and trends in the use of theories; advances in the understanding of visuo spatial reasoning; the use and role of diagrams and gestures; advances in the understanding of the role of digital technologies; advances in the understanding of the teaching and learning of definitions; advances in the understanding of the teaching and learning of the proving process; and, moving beyond traditional Euclidean approaches. Within each theme, we identify relevant research and also offer commentary on future directions. KW - Geometry KW - Technology KW - Diagrams KW - Definitions KW - Gestures KW - Proving KW - Digital technology KW - Visuospatial reasoning Y1 - 2016 U6 - https://doi.org/10.1007/s11858-016-0796-6 SN - 1863-9690 SN - 1863-9704 VL - 48 SP - 691 EP - 719 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Kistner, Saskia A1 - Burns, Bruce D. A1 - Vollmeyer, Regina A1 - Kortenkamp, Ulrich T1 - The importance of understanding: Model space moderates goal specificity effects JF - The quarterly journal of experimental psychology N2 - The three-space theory of problem solving predicts that the quality of a learner's model and the goal specificity of a task interact on knowledge acquisition. In Experiment 1 participants used a computer simulation of a lever system to learn about torques. They either had to test hypotheses (nonspecific goal), or to produce given values for variables (specific goal). In the good- but not in the poor-model condition they saw torque depicted as an area. Results revealed the predicted interaction. A nonspecific goal only resulted in better learning when a good model of torques was provided. In Experiment 2 participants learned to manipulate the inputs of a system to control its outputs. A nonspecific goal to explore the system helped performance when compared to a specific goal to reach certain values when participants were given a good model, but not when given a poor model that suggested the wrong hypothesis space. Our findings support the three-space theory. They emphasize the importance of understanding for problem solving and stress the need to study underlying processes. KW - Goal specificity KW - Problem solving KW - Three-space theory KW - Scientific discovery learning Y1 - 2016 U6 - https://doi.org/10.1080/17470218.2015.1076865 SN - 1747-0218 SN - 1747-0226 VL - 69 SP - 1179 EP - 1196 PB - Optical Society of America CY - Abingdon ER - TY - JOUR A1 - Kortenkamp, Ulrich A1 - Monaghan, John A1 - Trouche, Luc T1 - Jonathan M Borwein (1951-2016): exploring, experiencing and experimenting in mathematics - an inspiring journey in mathematics JF - Educational studies in mathematics : an international journal Y1 - 2016 U6 - https://doi.org/10.1007/s10649-016-9729-0 SN - 0013-1954 SN - 1573-0816 VL - 93 SP - 131 EP - 136 PB - Springer CY - Dordrecht ER - TY - CHAP A1 - Bender, Benedict A1 - Grum, Marcus T1 - Entwicklung eines Architekturkonzepts zum flexiblen Einsatz von Analytics T2 - Proceedings INFORMATIK - Jahrestagung der Gesellschaft für Informatik e.V. ; Lecture Notes in Informatics (LNI) N2 - Die optimale Dimensionierung von IT-Hardware stellt Entscheider aufgrund der stetigen Weiterentwicklung zunehmend vor Herausforderungen. Dies gilt im Speziellen auch für Analytics-Infrastrukturen, die zunehmend auch neue Software zur Analyse von Daten einsetzen, welche in den Ressourcenanforderungen stark variieren. Damit eine flexible und gleichzeitig effiziente Gestaltung von Analytics-Infrastrukturen erreicht werden kann, wird ein dynamisch arbeitendes Architekturkonzept vorgeschlagen, das Aufgaben auf Basis einer systemspezifischen Entscheidungsmaxime mit Hilfe einer Eskalationsmatrix verteilt und hierfür Aufgabencharakteristiken sowie verfügbare Hardwareausstattungen entsprechend ihrer Auslastung berücksichtigt. KW - Analytics KW - Architekturkonzept KW - Cyber-Phsysische Systeme KW - Cloud KW - Internet of Things Y1 - 2016 UR - https://dl.gi.de/handle/20.500.12116/1189 IS - P259 SP - 815 EP - 824 PB - Gesellschaft für Informatik e.V. CY - Bonn ER - TY - JOUR A1 - Soemer, Alexander A1 - Saito, Satoru T1 - Domain-specific processing in short-term serial order memory JF - Journal of memory and language N2 - Recent studies of short-term serial order memory have suggested that the maintenance of order information does not involve domain-specific processes. We carried out two dual task experiments aimed at resolving several ambiguities in those studies. In our experiments, encoding and response of one serial reconstruction task was embedded within encoding and response of a concurrent serial reconstruction task. Order demands in both tasks were independently varied so as to find revealing patterns of interference between the two tasks. In Experiment 1, participants were to maintain and reconstruct the order of a list of verbal materials, while maintaining a list of spatial materials or vice-versa. Increasing the order demands in the outer reconstruction task resulted in small or non reliable performance decrements in the embedded reconstruction task. Experiment 2 sought to compare these results against two same-domain baseline conditions (two verbal lists or two spatial lists). In all conditions, increasing order demands in the outer task resulted in small or non-reliable performance decrements in the embedded task. However, performance in the embedded tasks was generally lower in the same-domain baseline conditions than in the cross-domain conditions. We argue that the main effect of domain in Experiment 2 indicates the contribution of domain-specific processes to short-term serial order maintenance. In addition, we interpret the failure to find consistent cross-list interference irrespective of domain as indicating the involvement of grouping mechanisms in concurrently performed serial order tasks. (C) 2015 Elsevier Inc. All rights reserved. KW - Serial order memory KW - Verbal memory KW - Spatial memory KW - Domain specificity KW - Working memory Y1 - 2016 U6 - https://doi.org/10.1016/j.jml.2015.12.003 SN - 0749-596X SN - 1096-0821 VL - 88 SP - 1 EP - 17 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Soemer, Alexander A1 - Schwan, Stephan T1 - Task-Appropriate Visualizations: Can the Very Same Visualization Format Either Promote or Hinder Learning Depending on the Task Requirements? JF - The journal of educational psychology N2 - In a series of experiments, we tested a recently proposed hypothesis stating that the degree of alignment between the form of a mental representation resulting from learning with a particular visualization format and the specific requirements of a learning task determines learning performance (task-appropriateness). Groups of participants were required to learn the stroke configuration, the stroke order, or the stroke directions of a set of Chinese pseudocharacters. For each learning task, participants were divided into groups receiving dynamic, static-sequential, or static visualizations. An old/new character recognition task was given at test. The results showed that learning both stroke configuration and stroke order was best with static pictures (Experiments 1 and 2), while there was no reliable difference between the groups for learning stroke direction (Experiment 3). An additional experiment, however, revealed that learning with sequential pictures was superior when testing was carried out with sequential pictures, irrespective of the learning task (Experiment 4). The combined evidence from all experiments speaks against task requirements playing a role in determining the effectiveness of a visualization format. Furthermore, the evidence supports the view that a high degree of congruence between information presented during learning and information presented at test results in better learning (study-test congruence). Implications for instructional design are discussed. KW - animations KW - pictures KW - task requirements KW - study-test congruence KW - Chinese characters Y1 - 2016 U6 - https://doi.org/10.1037/edu0000093 SN - 0022-0663 SN - 1939-2176 VL - 108 SP - 960 EP - 968 PB - American Psychological Association CY - Washington ER - TY - CHAP A1 - Knoth, Alexander Henning A1 - Kiy, Alexander A1 - Müller, Ina T1 - Das erste Semester von Studierenden der Wirtschafts- und Sozialwissenschaften im Spiegel der Reflect-App T2 - DeLFI 2016 - Die 14. E-Learning Fachtagung Informatik 11.-14. September 2016 Potsdam N2 - Mobile Applikationen eignen sich als strukturelle Unterstützungsangebote für Studierende während des Studieneinstiegs. Durch die App Reflect.UP werden Studienorganisation, Studieninhalte und -ziele von Studierenden reflektiert. Der bewusste Umgang mit dem studentischen Kompetenzerwerb als wissenschaftliche eflexionskompetenz ist immanenter Bestandteil der akademischen Professionalisierung und steht in diesem Beitrag im Vordergrund. Gezeigt wird, wie aus Studienordnungen und Modulbeschreibungen systematisch Fragen zur studentischen Reflexion herausgearbeitet werden und dadurch ein Kompetenzraster entsteht. Die durch den praktischen Einsatz von Reflect.UP gewonnenen Daten werden ausgewertet und dahingehend diskutiert, welche Rückschlüsse sich hieraus auf die Problemlagen und Lernprozesse der Studierenden sowie für die Studiengangsorganisation(en) ziehen lassen. Darüber hinaus werden die Stärken und Schwächen einer mobilen Applikation als sozial- und informationswissenschaftliches Amalgam zur strukturellen Unterstützung der Studieneingangsphase reflektiert. KW - Studieneinstieg KW - Studienorganisation KW - App KW - Reflexion KW - Professionalisierung Y1 - 2016 UR - http://subs.emis.de/LNI/Proceedings/Proceedings262/article13.html SN - 978-3-88579-656-5 IS - P-262 SP - 59 EP - 70 PB - Gesellschaft für Informatik e.V. CY - Bonn ER - TY - JOUR A1 - Ly, Ibrahim A1 - Tarkhanov, Nikolai Nikolaevich T1 - A Rado theorem for p-harmonic functions JF - Boletin de la Sociedad Matemática Mexicana N2 - Let A be a nonlinear differential operator on an open set X subset of R-n and S a closed subset of X. Given a class F of functions in X, the set S is said to be removable for F relative to A if any weak solution of A(u) = 0 in XS of class F satisfies this equation weakly in all of X. For the most extensively studied classes F, we show conditions on S which guarantee that S is removable for F relative to A. KW - Quasilinear equations KW - Removable sets KW - p-Laplace equation Y1 - 2016 U6 - https://doi.org/10.1007/s40590-016-0109-7 SN - 1405-213X SN - 2296-4495 VL - 22 SP - 461 EP - 472 PB - Springer CY - Basel ER - TY - GEN A1 - Esguerra, Alejandro ED - Esguerra, Alejandro ED - Helmerich, Nicole ED - Risse, Thomas T1 - Conclusion T2 - Sustainability Politics and Limited Statehood: Contesting the New Modes of Governance N2 - This chapter revisits the role of the new modes of governance in areas of limited statehood. First, it states that there is no linear relationship between degrees of statehood and the overall effectiveness of new modes of sustainability governance. Second, the chapter states that, in most of the cases, national governments are hesitant or even actively hamper the development of new modes of governance. Third, it shows that the absence of the shadow of hierarchy can indeed lead to ineffective new modes of governance. However, the shadow of hierarchy does not necessarily need to be cast by states. Finally, the author reviews the complexities involved in participatory practices, stressing the importance of institutional structures and knowledgeable brokers. The chapter concludes by outlining fields for future research. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_9 SP - 211 EP - 224 PB - Cham CY - Basingstoke ER - TY - GEN A1 - Esguerra, Alejandro A1 - Helmerich, Nicole A1 - Risse, Thomas T1 - Introduction T2 - Sustainability Politics and Limited Statehood: Contesting the New Modes of Governance N2 - The Paris Agreement for Climate Change or the Sustainable Development Goals (SDGs) rely on new modes of governance for implementation. Indeed, new modes of governance such as market-based instruments, public-private partnerships or multi-stakeholder initiatives have been praised for playing a pivotal role in effective and legitimate sustainability governance. Yet, do they also deliver in areas of limited statehood? States such as Malaysia or the Dominican Republic partly lack the ability to implement and enforce rules; their statehood is limited. This introduction provides the analytical framework of this volume and critically examines the performance of new modes of governance in areas of limited statehood, drawing on the book’s in-depth case studies on issues of climate change, biodiversity, and health. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_1 SP - 1 EP - 22 PB - Palgrave Macmillan, Cham CY - Basingstoke ER - TY - GEN A1 - Esguerra, Alejandro T1 - "A Comment That Might Help Us to Move Along" BT - Brokers in Negotiation Systems T2 - Sustainability Politics and Limited Statehood : Contesting the New Modes of Governance N2 - This chapter investigates the trajectory of establishing the Forest Stewardship Council (FSC) in the early 1990s as the first private transnational certification organization with an antagonistic stakeholder body. Its main contribution is a micro-analysis of the founding assembly in 1993. By investigating the role of brokers within the negotiation as one institutional scope condition for ‘arguing’ having occurred, the chapter adopts a dramaturgical approach. It contends that the authority of brokers is not necessarily institutionally given, but needs to be gained: brokers have to prove situationally that their knowledge is relevant and that they are speaking impartially in the interest of progress rather than their own. The chapter stresses the importance of procedural knowledge which brokers provide in contrast to policy knowledge. Y1 - 2016 SN - 978-3-319-39871-6 SN - 978-3-319-39870-9 U6 - https://doi.org/10.1007/978-3-319-39871-6_2 SP - 25 EP - 46 PB - Cham CY - Basingstoke ER - TY - GEN A1 - Martinez-Valdes, Eduardo A1 - Negro, Francesco A1 - Laine, Christopher M. A1 - Falla, Deborah L. A1 - Mayer, Frank A1 - Farina, Dario T1 - Identifying motor units in longitudinal studies with high-density surface electromyography T2 - Converging clinical and engineering research on neurorehabilitation II N2 - We investigated the possibility to identify motor units (MUs) with high-density surface electromyography (HDEMG) over experimental sessions in different days. 10 subjects performed submaximal knee extensions across three sessions in three days separated by one week, while EMG was recorded from the vastus medialis muscle with high-density electrode grids. The shapes of the MU action potentials (MUAPs) over multiple channels extracted from HDEMG decomposition were matched across sessions by cross-correlation. Forty and twenty percent of the MUs decomposed could be tracked across two and three sessions, respectively (average cross correlation 0.85 +/- 0.04). The estimated properties of the matched motor units were similar across the sessions. For example, mean discharge rate and recruitment thresholds were measured with an intra-class correlation coefficient (ICCs) > 0.80. These results strongly suggest that the same MUs were indeed identified across sessions. This possibility will allow monitoring changes in MU properties following interventions or during the progression of neuromuscular disorders. Y1 - 2016 SN - 978-3-319-46669-9 SN - 978-3-319-46668-2 U6 - https://doi.org/10.1007/978-3-319-46669-9_27 SN - 2195-3562 VL - 15 SP - 147 EP - 151 PB - Springer CY - Cham ER - TY - JOUR A1 - Kühne, Franziska A1 - Meinders, C. A1 - Mohr, H. A1 - Hafenbrack, K. A1 - Kieseritzky, K. A1 - Rosenberger, C. A1 - Haerter, M. A1 - Schulz-Kindermann, F. A1 - Klinger, R. A1 - Nestoriuc, A. Y. T1 - Psychological treatments for pain in cancer patients. A systematic review on the current state of research JF - Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie N2 - In cancer patients, pain is one of the main symptoms and especially in the late stages of disease, these symptoms can be associated with considerable suffering. In psycho-oncology, preliminary psychological therapies targeting cancer pain have been tested; however, a systematic review of available interventions is lacking, especially considering their dissemination, evidence base, study quality, and the comparison with established treatments. Therefore, the aim of the current study is to systematically review the current research on psychological treatments for pain in cancer patients. During May 2014, MEDLINE, PsycINFO, PSYNDEX, and CENTRAL databases were searched. Psychological treatments for pain in adult cancer patients studied in randomized, controlled trials (RCTs) and referring to pain as primary or secondary outcome were included. After examination for inclusion, structured data extraction and assessment followed. Data were synthesized narratively. In the review, 32 RCTs were included. Studies mainly referred to patients with breast cancer or patients in earlier stages of the disease. The methodological quality of included studies was heterogeneous. Most commonly, short interventions were delivered by nurses in out-patient settings. Interventions including education and relaxation techniques were utilized most often, followed by interventions with behavioral or cognitive components. A need for research persists regarding efficacy of current psychotherapeutic interventions, or the role of mediator variables (e. g., coping) on pain perception in cancer patients. Studies with high methodological quality which comprehensively and transparently report on interventions and designs are lacking. KW - Neoplasms, psychology KW - Education, patients KW - Relaxation KW - Behavior therapy KW - Cognitive therapy Y1 - 2016 U6 - https://doi.org/10.1007/s00482-016-0169-7 SN - 0932-433X SN - 1432-2129 VL - 30 SP - 496 EP - 509 PB - Springer CY - New York ER - TY - THES A1 - Schulz, Michael Karl T1 - Emanzipation in Stadt und Staat BT - Die Judenpolitik in Danzig 1807-1847 T2 - Hamburger Beiträge zur Geschichte der deutschen Juden ; 46 N2 - Die Danziger Verwaltungspraxis des frühen 19. Jahrhunderts im Nexus von Reform, Restauration, Emanzipation und antijüdischen Vorurteilen. Michał Szulc analysiert die Umsetzung der staatlichen Judenpolitik in der preußischen Provinz am Beispiel Danzigs. Dabei zeigt er die Emanzipation der Juden als Kampfplatz von Interessengruppen und individuellen Akteuren. Der Autor untersucht sowohl die Diskussionen vor Ort als auch in machtpolitischen Zentren wie Berlin und Paris. Deutlich wird dabei die Diskrepanz zwischen gesetzlicher Norm und Alltagspraxis, zwischen politischem Programm und dessen tatsächlicher Wirkung. In diesem politisch-rechtlichen Prozess setzten sich Staat und Stadt konfrontativ über die Lage der Juden in Danzig auseinander. Akteure wie Napoleon I., König Friedrich Wilhelm III. oder Staatskanzler Karl August von Hardenberg versuchten mit unterschiedlichem Erfolg das Ausmaß der Emanzipation ebenso so zu prägen, wie es 'einfache Leute', etwa der Rabbinatskandidat Bram oder der Stadtverordnete Zernecke, taten. Die Rollen der Protagonisten waren dabei variabel: Einige Staatsbeamte vertraten die Position der Stadt, manche Bürger die des Staates. Zudem entwickelte sich im Laufe der Debatte jenseits rechtlicher Normen eine lokale Praxis, die Juden mehr Raum in der Gesellschaft gewährte. Y1 - 2016 SN - 978-3-8353-1853-3 PB - Wallstein CY - Göttingen ER - TY - JOUR A1 - Walter, J. A1 - Hamann, Göran A1 - Lück, Erika A1 - Klingenfuss, C. A1 - Zeitz, Jutta T1 - Stratigraphy and soil properties of fens: Geophysical case studies from northeastern Germany JF - Catena : an interdisciplinary journal of soil science, hydrology, geomorphology focusing on geoecology and landscape evolution N2 - The determination of the total carbon storage of peatlands is of high relevance in the context of climate-change mitigation efforts. This determination relies on data about stratigraphy and peat properties, which are conventionally collected by coring. Ground-penetrating radar (GPR) and electrical resistivity imaging (ERI) can support these point data by providing subsoil information in two-dimensional cross-sections. In this study, GPR and ERI were conducted at two groundwater-fed fen sites located in the temperate zone in north-east Germany. The fens of this region are embedded in low conductive glacial sand and are characterised by thick layers of gyttja, which can be either mineral or organic. The two study sites are representative of this region with respect to stratigraphy (total thickness, peat and gyttja types) and ecological conditions (pH-value, trophic condition). The aim of this study is to assess the suitability of GPR and ERI to detect stratigraphy and peat properties under these characteristic site conditions. Results show that GPR clearly detects the interfaces between (i) Carex and brown-moss peat, (ii) brown-moss peat and organic gyttja, (iii) organic- and mineral gyttja, and (iv) mineral gyttja and the parent material (glacial sand). These layers differ in bulk density and the related organic matter content. ERI, however, does not delineate these layers; rather it delineates regions of varying properties. At our base-rich site, pore fluid conductivity and cation.exchange capacity are the main factors that determine peat electrical conductivity (reverse of resistivity), whereas organic matter and water content are most influential at the more acidic site. Thus the correlation between peat properties and electrical conductivity are driven by site-specific conditions, which are mainly determined by the solute load in the groundwater at fens. When the total organic deposits exceed a thickness of 5 m, the depth of investigation by GPR is limited due to increasing attenuation. This is not a limiting factor for ERI, where the transition from organic deposits to glacial sand is visible at both sites. Due to these specific sensitivities, a combined application of GPR and ERI meets the demand for up-to-date information on carbon storage of peatlands, which is, moreover, very site-specific because of the inherent variety of ecological conditions and stratigraphy between peatlands in general and between fens and bogs in particular. (C) 2016 Elsevier B.V. All rights reserved. KW - Fen stratigraphy KW - Peat properties KW - Gyttja KW - Ground penetrating radar KW - Electrical conductivity KW - Electrical resistivity imaging Y1 - 2016 U6 - https://doi.org/10.1016/j.catena.2016.02.028 SN - 0341-8162 SN - 1872-6887 VL - 142 SP - 112 EP - 125 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Reyes, Anibal M. A1 - Vazquez, Diego S. A1 - Zeida, Ari A1 - Hugo, Martin A1 - Dolores Pineyro, M. A1 - Ines De Armas, Maria A1 - Estrin, Dario A1 - Radi, Rafael A1 - Santos, Javier A1 - Trujillo, Madia T1 - PrxQ B from Mycobacterium tuberculosis is a monomeric, thioredoxin-dependent and highly efficient fatty acid hydroperoxide reductase JF - Free radical biology and medicine : the official journal of the Oxygen Society, a constituent member of the International Society for Free Radical Research N2 - Mycobacterium tuberculosis (M. tuberculosis) is the intracellular bacterium responsible for tuberculosis disease (TD). Inside the phagosomes of activated macrophages, M. tuberculosis is exposed to cytotoxic hydroperoxides such as hydrogen peroxide, fatty acid hydroperoxides and peroxynitrite. Thus, the characterization of the bacterial antioxidant systems could facilitate novel drug developments. In this work, we characterized the product of the gene Rv1608c from M. tuberculosis, which according to sequence homology had been annotated as a putative peroxiredoxin of the peroxiredoxin Q subfamily (PrxQ B from M. tuberculosis or MtPrxQ B). The protein has been reported to be essential for M. tuberculosis growth in cholesterol-rich medium. We demonstrated the M. tuberculosis thioredoxin B/C-dependent peroxidase activity of MtPrxQ B, which acted as a two-cysteine peroxiredoxin that could function, although less efficiently, using a one-cysteine mechanism. Through steady-state and competition kinetic analysis, we proved that the net forward rate constant of MtPrxQ B reaction was 3 orders of magnitude faster for fatty acid hydroperoxides than for hydrogen peroxide (3x10(6) vs 6x10(3) M-1 s(-1), respectively), while the rate constant of peroxynitrite reduction was (0.6-1.4) x10(6) M-1 s(-1) at pH 7.4. The enzyme lacked activity towards cholesterol hydroperoxides solubilized in sodium deoxycholate. Both thioredoxin B and C rapidly reduced the oxidized form of MtPrxQ B, with rates constants of 0.5x10(6) and 1x10(6) M-1 s(-1), respectively. Our data indicated that MtPrxQ B is monomeric in solution both under reduced and oxidized states. In spite of the similar hydrodynamic behavior the reduced and oxidized forms of the protein showed important structural differences that were reflected in the protein circular dichroism spectra. KW - Mycobacterium tuberculosis KW - Peroxiredoxin KW - Thioredoxin KW - Peroxynitrite KW - Fatty acid hydroperoxides KW - Thiol-dependent peroxidase KW - Peroxidatic and resolving cysteine Y1 - 2016 U6 - https://doi.org/10.1016/j.freeradbiomed.2016.10.005 SN - 0891-5849 SN - 1873-4596 VL - 101 SP - 249 EP - 260 PB - Elsevier CY - New York ER - TY - JOUR A1 - Müller, Juliane A1 - Müller, Steffen A1 - Stoll, Josefine A1 - Rector, Michael V. A1 - Baur, Heiner A1 - Mayer, Frank T1 - Influence of Load on Three-Dimensional Segmental Trunk Kinematics in One-Handed Lifting: A Pilot Study JF - Journal of applied biomechanics N2 - Stability of the trunk is relevant in determining trunk response to different loading in everyday tasks initiated by the limbs. Descriptions of the trunk’s mechanical movement patterns in response to different loads while lifting objects are still under debate. Hence, the aim of this study was to analyze the influence of weight on 3-dimensional segmental motion of the trunk during 1-handed lifting. Ten asymptomatic subjects were included (29 ± 3 y; 1.79 ± 0.09 m; 75 ± 14 kg). Subjects lifted 3× a light and heavy load from the ground up onto a table. Three-dimensional segmental trunk motion was measured (12 markers; 3 segments: upper thoracic area [UTA], lower thoracic area [LTA], lumbar area [LA]). Outcomes were total motion amplitudes (ROM;[°]) for anterior flexion, lateral flexion, and rotation of each segment. The highest ROM was observed in the LTA segment (anterior flexion), and the smallest ROM in the UTA segment (lateral flexion). ROM differed for all planes between the 3 segments for both tasks (P < .001). There were no differences in ROM between light and heavy loads (P > .05). No interaction effects (load × segment) were observed, as ROM did not reveal differences between loading tasks. Regardless of weight, the 3 segments did reflect differences, supporting the relevance of multisegmental analysis. KW - trunk motion KW - kinematic trunk model KW - everyday task KW - MiSpEx* Y1 - 2016 U6 - https://doi.org/10.1123/jab.2015-0227 SN - 1065-8483 SN - 1543-2688 VL - 32 SP - 520 EP - 525 PB - Human Kinetics Publ. CY - Champaign ER - TY - JOUR A1 - Guillemoteau, Julien A1 - Simon, Francois-Xavier A1 - Lück, Erika A1 - Tronicke, Jens T1 - 1D sequential inversion of portable multi-configuration electromagnetic induction data JF - Near surface geophysics N2 - We present an algorithm that performs sequentially one-dimensional inversion of subsurface magnetic permeability and electrical conductivity by using multi-configuration electromagnetic induction sensor data. The presented method is based on the conversion of the in-phase and out-of-phase data into effective magnetic permeability and electrical conductivity of the equivalent homogeneous half-space. In the case of small-offset systems, such as portable electromagnetic induction sensors, for which in-phase and out-of-phase data are moderately coupled, the effective half-space magnetic permeability and electrical conductivity can be inverted sequentially within an iterative scheme. We test and evaluate the proposed inversion strategy using synthetic and field examples. First, we apply it to synthetic data for some highly magnetic environments. Then, the method is tested on real field data acquired in a basaltic environment to image a formation of archaeological interest. These examples demonstrate that a joint interpretation of in-phase and out-of-phase data leads to a better characterisation of the subsurface in magnetic environments such as volcanic areas. Y1 - 2016 U6 - https://doi.org/10.3997/1873-0604.2016029 SN - 1569-4445 SN - 1873-0604 VL - 14 SP - 423 EP - 432 PB - Wiley-VCH CY - Houten ER - TY - JOUR A1 - Höhle, Barbara A1 - Berger, Frauke A1 - Sauermann, Antje T1 - Information structure in first language acquisition JF - The Oxford handbook of information structure Y1 - 2016 SN - 978-0-19-964267-0 SP - 562 EP - 580 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Nickerson, David A1 - Atalag, Koray A1 - de Bono, Bernard A1 - Geiger, Joerg A1 - Goble, Carole A1 - Hollmann, Susanne A1 - Lonien, Joachim A1 - Mueller, Wolfgang A1 - Regierer, Babette A1 - Stanford, Natalie J. A1 - Golebiewski, Martin A1 - Hunter, Peter T1 - The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable JF - Interface focus N2 - Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level through to whole populations of individuals must be integrated, then personalized. This requires interoperability with multiple disparate and geographically separated data sources, and myriad computational software tools. Extracting and producing knowledge from such sources, even when the databases and software are readily available, is a challenging task. Despite the difficulties, researchers must frequently perform these tasks so that available knowledge can be continually integrated into the common framework required to realize the Human Physiome. Software and infrastructures that support the communities that generate these, together with their underlying standards to format, describe and interlink the corresponding data and computer models, are pivotal to the Human Physiome being realized. They provide the foundations for integrating, exchanging and re-using data and models efficiently, and correctly, while also supporting the dissemination of growing knowledge in these forms. In this paper, we explore the standards, software tooling, repositories and infrastructures that support this work, and detail what makes them vital to realizing the Human Physiome. KW - Human Physiome KW - standards KW - repositories KW - service infrastructure KW - reproducible science KW - managing big data Y1 - 2016 U6 - https://doi.org/10.1098/rsfs.2015.0103 SN - 2042-8898 SN - 2042-8901 VL - 6 SP - 57 EP - 61 PB - Royal Society CY - London ER - TY - JOUR A1 - Mueller, Juliane A1 - Engel, Tilman A1 - Mueller, Steffen A1 - Kopinski, Stephan A1 - Baur, Heiner A1 - Mayer, Frank T1 - Neuromuscular response of the trunk to sudden gait disturbances: Forward vs. backward perturbation JF - Journal of electromyography and kinesiology N2 - The study aimed to analyse neuromuscular activity of the trunk comparing four different perturbations during gait. Thirteen subjects (28 +/- 3 yrs) walked (1 m/s) on a split-belt treadmill, while 4 (belt) perturbations (F1, F2, B1, B2) were randomly applied. Perturbations differed, related to treadmill belt translation, in direction (forward (F)/backward (B)) and amplitude (20 m/s(2) (1)/40 m/s(2) (2)). Trunk muscle activity was assessed with a 12-lead-EMG. EMG-RMS [%] (0-200 ms after perturbation; normalized to RMS of normal gait) was analyzed for muscles and four trunk areas (ventral left/right; dorsal left/right). Ratio of ventral: dorsal muscles were calculated. Muscle onset [ms] was determined. Data analysis was conducted descriptively, followed by ANOVA (post hoc Tukey-Kramer (alpha = 0.05)). All perturbations lead to an increase in EMG-RMS (428 +/- 289%). F1 showed the lowest and F2 the highest increase for the flexors. B2 showed the highest increase for the extensors. Significant differences between perturbations could be observed for 6 muscles, as well as the 4 trunk areas. Ratio analysis revealed no significant differences (range 1.25 (B1) to 1.71 (F2) between stimuli. Muscle response time (ventral: 87.0 +/- 21.7 ms; dorsal: 88.4 +/- 17.0 ms) between stimuli was only significant (p = 0.005) for the dorsal muscles. Magnitude significantly influences neuromuscular trunk response patterns in healthy adults. Regardless of direction ventral muscles always revealed higher relative increase of activity while compensating the walking perturbations. (C) 2016 Elsevier Ltd. All rights reserved. KW - Stumbling KW - Gait perturbation KW - EMG KW - Core KW - MiSpEx* Y1 - 2016 U6 - https://doi.org/10.1016/j.jelekin.2016.07.005 SN - 1050-6411 SN - 1873-5711 VL - 30 SP - 168 EP - 176 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Klinnert, Anne T1 - Rohstoffpolitik im 21. Jahrhundert JF - WeltTrends : das außenpolitische Journal N2 - In den 2000er-Jahren stiegen die Rohstoffpreise enorm an. Auslöser waren die wirtschaftliche Entwicklung der Schwellenländer, allen voran Chinas, sowie der gestiegene Rohstoffbedarf durch technologische Innovationen. Diese „Rohstoffkrise“ veränderte das Verhältnis der Rohstoff exportierenden und importierenden Staaten zueinander. Auch wird Rohstoffpolitik nicht mehr nur unter wirtschaftlichen, sondern ebenso unter ökologischen und sozialen Kriterien betrachtet. Der Beitrag erläutert die Ursachen und benennt Auswirkungen der Krise. Y1 - 2016 SN - 978-3-945878-25-5 SN - 0944-8101 VL - 24 IS - 118 SP - 24 EP - 29 PB - WeltTrends CY - Potsdam ER - TY - JOUR A1 - Krüger, Tobias A1 - Kelling, Alexandra A1 - Schilde, Uwe A1 - Linker, Torsten T1 - Simple Synthesis of gamma-Spirolactams by Birch Reduction of Benzoic Acids JF - European journal of organic chemistry N2 - A convenient synthesis of gamma-spirolactams in only two steps was developed. Birch reduction of benzoic acids and immediate alkylation with chloroacetonitrile afforded cyclohexadienes in high yields. The products could be isolated by crystallization on a large scale in analytically pure form. Subsequent hydrogenation with platinum(IV) oxide as the catalyst reduced the nitrile functionality and the double bonds in the same step with excellent stereoselectivity. The relative configurations were determined unequivocally by X-ray analyses. Direct cyclization of the intermediary formed amino acids afforded the desired gamma-spirolactams in excellent overall yields. The procedure is characterized by few steps, cheap reagents, and can be performed on a large scale, interesting for industrial processes. KW - Diastereoselectivity KW - Hydrogenation KW - Lactams KW - Reduction KW - Synthetic methods Y1 - 2016 U6 - https://doi.org/10.1002/ejoc.201601650 SN - 1434-193X SN - 1099-0690 IS - 6 SP - 1074 EP - 1077 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Kunow, Rüdiger T1 - Postcolonial theory and old age: An explorative essay JF - Journal of aging studie KW - Postcolonial theory KW - Old age KW - Positional difference KW - Subaltemity KW - Postcolonial aspects of old age KW - Cultural theory Y1 - 2016 U6 - https://doi.org/10.1016/j.jaging.2016.06.004 SN - 0890-4065 SN - 1879-193X VL - 39 SP - 101 EP - 108 PB - Elsevier CY - New York ER - TY - JOUR A1 - Drummer, Janna-Deborah A1 - van der Meer, Elke A1 - Schaadt, Gesa T1 - Event-related potentials in response to violations of content and temporal event knowledge JF - Neuropsychologia : an international journal in behavioural and cognitive neuroscience N2 - Scripts that store knowledge of everyday events are fundamentally important for managing daily routines. Content event knowledge (i.e., knowledge about which events belong to a script) and temporal event knowledge (i.e., knowledge about the chronological order of events in a script) constitute qualitatively different forms of knowledge. However, there is limited information about each distinct process and the time course involved in accessing content and temporal event knowledge. Therefore, we analyzed event-related potentials (ERPs) in response to either correctly presented event sequences or event sequences that contained a content or temporal error. We found an N400, which was followed by a posteriorly distributed P600 in response to content errors in event sequences. By contrast, we did not find an N400 but an anteriorly distributed P600 in response to temporal errors in event sequences. Thus, the N400 seems to be elicited as a response to a general mismatch between an event and the established event model. We assume that the expectancy violation of content event knowledge, as indicated by the N400, induces the collapse of the established event model, a process indicated by the posterior P600. The expectancy violation of temporal event knowledge is assumed to induce an attempt to reorganize the event model in working memory, a process indicated by the frontal P600. (C) 2015 Elsevier Ltd. All rights reserved. KW - Event model KW - Content event knowledge KW - Temporal event knowledge KW - N400 KW - P600 Y1 - 2016 U6 - https://doi.org/10.1016/j.neuropsychologia.2015.11.007 SN - 0028-3932 SN - 1873-3514 VL - 80 SP - 47 EP - 55 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Metz, Johannes A1 - Tielboerger, Katja T1 - Spatial and temporal aridity gradients provide poor proxies for plant-plant interactions under climate change: a large-scale experiment JF - Functional ecology : an official journal of the British Ecological Society N2 - 1. Plant-plant interactions may critically modify the impact of climate change on plant communities. However, the magnitude and even direction of potential future interactions remains highly debated, especially for water-limited ecosystems. Predictions range from increasing facilitation to increasing competition with future aridification. 2. The different methodologies used for assessing plant-plant interactions under changing environmental conditions may affect the outcome but they are not equally represented in the literature. Mechanistic experimental manipulations are rare compared with correlative approaches that infer future patterns from current observations along spatial climatic gradients. 3. Here, we utilize a unique climatic gradient in combination with a large-scale, long-term experiment to test whether predictions about plant-plant interactions yield similar results when using experimental manipulations, spatial gradients or temporal variation. We assessed shrub-annual interactions in three different sites along a natural rainfall gradient (spatial) during 9 years of varying rainfall (temporal) and 8 years of dry and wet manipulations of ambient rainfall (experimental) that closely mimicked regional climate scenarios. 4. The results were fundamentally different among all three approaches. Experimental water manipulations hardly altered shrub effects on annual plant communities for the assessed fitness parameters biomass and survival. Along the spatial gradient, shrub effects shifted from clearly negative to mildly facilitative towards drier sites, whereas temporal variation showed the opposite trend: more negative shrub effects in drier years. 5. Based on our experimental approach, we conclude that shrub-annual interaction will remain similar under climate change. In contrast, the commonly applied space-for-time approach based on spatial gradients would have suggested increasing facilitative effects with climate change. We discuss potential mechanisms governing the differences among the three approaches. 6. Our study highlights the critical importance of long-term experimental manipulations for evaluating climate change impacts. Correlative approaches, for example along spatial or temporal gradients, may be misleading and overestimate the response of plant-plant interactions to climate change. KW - annual plant communities KW - climate manipulation KW - competition KW - facilitation KW - Mediterranean shrubland KW - nurse plant KW - rainfall gradient KW - Sarcopoterium spinosum KW - semi-arid KW - stress-gradient hypothesis Y1 - 2016 U6 - https://doi.org/10.1111/1365-2435.12599 SN - 0269-8463 SN - 1365-2435 VL - 30 SP - 20 EP - 29 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Bilton, Mark C. A1 - Metz, Johannes A1 - Tielboerger, Katja T1 - Climatic niche groups: A novel application of a common assumption predicting plant community response to climate change JF - Perspectives in plant ecology, evolution and systematics N2 - Defining species by their climatic niche is the simple and intuitive principle underlying Bioclimatic Envelope Model (BEM) predictions for climate change effects. However, these correlative models are often criticised for neglecting many ecological processes. Here, we apply the same niche principle to entire communities within a medium/long-term climate manipulation study, where ecological processes are inherently included. In a nine generation study in Israel, we manipulated rainfall (Drought -30%; Irrigation +30%; Control natural rainfall) at two sites which differ chiefly in rainfall quantity and variability. We analysed community responses to the manipulations by grouping species based on their climatic rainfall niche. These responses were compared to analyses based on single species, total densities, and commonly used taxonomic groupings. Climate Niche Groups yielded clear and consistent results: within communities, those species distributed in drier regions performed relatively better in the drought treatment, and those from wetter climates performed better when irrigated. In contrast, analyses based on other principles revealed little insight into community dynamics. Notably, most relationships were weaker at the drier, more variable site, suggesting that enhanced adaptation to variability may buffer climate change impacts. We provide robust experimental evidence that using climatic niches commonly applied in BEMs is a valid approach for eliciting community changes in response to climate change. However, we also argue that additional empirical information needs to be gathered using experiments in situ to correctly assess community vulnerability. Climatic Niche Groups used in this way, may therefore provide a powerful tool and directional testing framework to generalise and compare climate change impacts across habitats. (C) 2016 The Authors. Published by Elsevier GmbH. KW - Annual plant communities KW - Bioclimatic envelope modelling KW - Climate change manipulations KW - Experimental evidence KW - Plant functional groups KW - Rainfall niche Y1 - 2016 U6 - https://doi.org/10.1016/j.ppees.2016.02.006 SN - 1433-8319 VL - 19 SP - 61 EP - 69 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Rauch, Thomas A1 - Quinet, P. A1 - Hoyer, D. A1 - Werner, K. A1 - Richter, Philipp A1 - Kruk, J. W. A1 - Demleitner, M. T1 - VII. New Kr IV - VII oscillator strengths and an improved spectral analysis of the hot, hydrogen-deficient DO-type white dwarf RE 0503-289 JF - Plant physiology : an international journal devoted to physiology, biochemistry, cellular and molecular biology, biophysics and environmental biology of plants N2 - Context. For the spectral analysis of high-resolution and high signal-to-noise (S/N) spectra of hot stars, state-of-the-art non-local thermodynamic equilibrium (NLTE) model atmospheres are mandatory. These are strongly dependent on the reliability of the atomic data that is used for their calculation. Aims. New Kr IV-VII oscillator strengths for a large number of lines enable us to construct more detailed model atoms for our NLTE model-atmosphere calculations. This enables us to search for additional Kr lines in observed spectra and to improve Kr abundance determinations. Methods. We calculated Kr IV-VII oscillator strengths to consider radiative and collisional bound-bound transitions in detail in our NLTE stellar-atmosphere models for the analysis of Kr lines that are exhibited in high-resolution and high S/N ultraviolet (UV) observations of the hot white dwarf RE 0503-289. Results. We reanalyzed the effective temperature and surface gravity and determined T-eff = 70 000 +/- 2000 K and log (g/cm s(-2)) = 7.5 +/- 0.1. We newly identified ten Kr V lines and one Kr vi line in the spectrum of RE 0503-289. We measured a Kr abundance of 3.3 +/- 0.3 (logarithmic mass fraction). We discovered that the interstellar absorption toward RE 0503-289 has a multi-velocity structure within a radial-velocity interval of -40 km s(-1) < upsilon(rad) < +18 km s(-1). Conclusions. Reliable measurements and calculations of atomic data are a prerequisite for state-of-the-art NLTE stellar-atmosphere modeling. Observed Kr V-VII line profiles in the UV spectrum of the white dwarf RE 0503-289 were simultaneously well reproduced with our newly calculated oscillator strengths. KW - atomic data KW - line: identification KW - stars: abundances KW - stars: individual: RE 0503-289 KW - virtual observatory tools KW - stars: individual: RE 0457-281 Y1 - 2016 U6 - https://doi.org/10.1051/0004-6361/201628131 SN - 1432-0746 VL - 590 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Zum Hundertsten nichts Neues BT - Deutschsprachige Neuerscheinungen zum Ersten Weltkrieg (Teil II) BT - New German-language New Publications duringthe First World War (Part II) JF - Deutsche Zeitschrift für Geschichtswissenschaft T2 - For the Hundredth nothing Y1 - 2016 SN - 0044-2828 VL - 64 SP - 683 EP - 702 PB - Metropol-Verl. CY - Berlin ER - TY - THES A1 - Weidling, Stefan T1 - Neue Ansätze zur Verbesserung der Fehlertoleranz gegenüber transienten Fehlern in sequentiellen Schaltungen Y1 - 2016 ER - TY - THES A1 - Nieß, Günther T1 - Modellierung und Erkennung von technischen Fehlern mittels linearer und nichtlinearer Codes Y1 - 2016 ER - TY - JOUR A1 - Makowicz, Amber M. A1 - Tiedemann, Ralph A1 - Steele, Rachel N. A1 - Schlupp, Ingo T1 - Kin Recognition in a Clonal Fish, Poecilia formosa JF - PLoS one N2 - Relatedness strongly influences social behaviors in a wide variety of species. For most species, the highest typical degree of relatedness is between full siblings with 50% shared genes. However, this is poorly understood in species with unusually high relatedness between individuals: clonal organisms. Although there has been some investigation into clonal invertebrates and yeast, nothing is known about kin selection in clonal vertebrates. We show that a clonal fish, the Amazon molly (Poecilia formosa), can distinguish between different clonal lineages, associating with genetically identical, sister clones, and use multiple sensory modalities. Also, they scale their aggressive behaviors according to the relatedness to other females: they are more aggressive to non-related clones. Our results demonstrate that even in species with very small genetic differences between individuals, kin recognition can be adaptive. Their discriminatory abilities and regulation of costly behaviors provides a powerful example of natural selection in species with limited genetic diversity. Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0158442 SN - 1932-6203 VL - 11 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Lah, Ljerka A1 - Trense, Daronja A1 - Benke, Harald A1 - Berggren, Per A1 - Gunnlaugsson, Porvaldur A1 - Lockyer, Christina A1 - Öztürk, Ayaka A1 - Öztürk, Bayram A1 - Pawliczka, Iwona A1 - Roos, Anna A1 - Siebert, Ursula A1 - Skora, Krzysztof A1 - Vikingsson, Gisli A1 - Tiedemann, Ralph T1 - Spatially Explicit Analysis of Genome-Wide SNPs Detects Subtle Population Structure in a Mobile Marine Mammal, the Harbor Porpoise JF - PLoS one N2 - The population structure of the highly mobile marine mammal, the harbor porpoise (Phocoena phocoena), in the Atlantic shelf waters follows a pattern of significant isolation-by-distance. The population structure of harbor porpoises from the Baltic Sea, which is connected with the North Sea through a series of basins separated by shallow underwater ridges, however, is more complex. Here, we investigated the population differentiation of harbor porpoises in European Seas with a special focus on the Baltic Sea and adjacent waters, using a population genomics approach. We used 2872 single nucleotide polymor-phisms (SNPs), derived from double digest restriction-site associated DNA sequencing (ddRAD-seq), as well as 13 microsatellite loci and mitochondrial haplotypes for the same set of individuals. Spatial principal components analysis (sPCA), and Bayesian clustering on a subset of SNPs suggest three main groupings at the level of all studied regions: the Black Sea, the North Atlantic, and the Baltic Sea. Furthermore, we observed a distinct separation of the North Sea harbor porpoises from the Baltic Sea populations, and identified splits between porpoise populations within the Baltic Sea. We observed a notable distinction between the Belt Sea and the Inner Baltic Sea sub-regions. Improved delineation of harbor porpoise population assignments for the Baltic based on genomic evidence is important for conservation management of this endangered cetacean in threatened habitats, particularly in the Baltic Sea proper. In addition, we show that SNPs outperform microsatellite markers and demonstrate the utility of RAD-tags from a relatively small, opportunistically sampled cetacean sample set for population diversity and divergence analysis. Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0162792 SN - 1932-6203 VL - 11 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Zhu, Fangjun A1 - Schlupp, Ingo A1 - Tiedemann, Ralph T1 - Sequence Evolution and Expression of the Androgen Receptor and Other Pathway-Related Genes in a Unisexual Fish, the Amazon Molly, Poecilia formosa, and Its Bisexual Ancestors JF - PLoS one N2 - The all-female Amazon molly (Poecilia formosa) originated from a single hybridization of two bisexual ancestors, Atlantic molly (Poecilia mexicana) and sailfin molly (Poecilia latipinna). As a gynogenetic species, the Amazon molly needs to copulate with a heterospecific male, but the genetic information of the sperm-donor does not contribute to the next generation, as the sperm only acts as the trigger for the diploid eggs’ embryogenesis. Here, we study the sequence evolution and gene expression of the duplicated genes coding for androgen receptors (ars) and other pathway-related genes, i.e., the estrogen receptors (ers) and cytochrome P450, family19, subfamily A, aromatase genes (cyp19as), in the Amazon molly, in comparison to its bisexual ancestors. Mollies possess–as most other teleost fish—two copies of the ar, er, and cyp19a genes, i.e., arα/arβ, erα/erβ1, and cyp19a1 (also referred as cyp19a1a)/cyp19a2 (also referred to as cyp19a1b), respectively. Non-synonymous single nucleotide polymorphisms (SNPs) among the ancestral bisexual species were generally predicted not to alter protein function. Some derived substitutions in the P. mexicana and one in P. formosa are predicted to impact protein function. We also describe the gene expression pattern of the ars and pathway-related genes in various tissues (i.e., brain, gill, and ovary) and provide SNP markers for allele specific expression research. As a general tendency, the levels of gene expression were lowest in gill and highest in ovarian tissues, while expression levels in the brain were intermediate in most cases. Expression levels in P. formosa were conserved where expression did not differ between the two bisexual ancestors. In those cases where gene expression levels significantly differed between the bisexual species, P. formosa expression was always comparable to the higher expression level among the two ancestors. Interestingly, erβ1 was expressed neither in brain nor in gill in the analyzed three molly species, which implies a more important role of erα in the estradiol synthesis pathway in these tissues. Furthermore, our data suggest that interactions of steroid-signaling pathway genes differ across tissues, in particular the interactions of ars and cyp19as. Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0156209 SN - 1932-6203 VL - 11 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Marrone, F. A1 - Havenstein, Katja A1 - Tiedemann, Ralph A1 - Ketmaier, V. T1 - Identification and characterization of five polymorphic microsatellite loci in the freshwater copepod Hemidiaptomus gurneyi (Copepoda: Calanoida: Diaptomidae) JF - The Italian journal of zoology N2 - Hemidiaptomus diaptomid copepods are known to be excellent biological indicators for the highly biodiverse crustacean communities inhabiting Mediterranean temporary ponds (MTPs), an endangered inland water habitat whose conservation is considered a priority according to the "Habitat Directive" of the European Union. This study reports on the characterization of five polymorphic microsatellite loci in Hemidiaptomus gurneyi, to be used as markers for fine-scale studies on the population genetic structure and metapopulation dynamics of a typical and obligate MTP dweller. The five selected loci proved to be polymorphic in the species, with three to five polymorphic loci per studied population. Overall, mean heterozygosity scored for all loci and populations was lower than that reported for the few other diaptomid species for which microsatellite loci have been to date described; this is possibly due to the intrinsically fragmented and isolated peculiar habitat inhabited by the species. Furthermore, the presence of indels within the flanking regions of selected loci was scored. This study, albeit confirming the technical difficulties in finding proper microsatellite markers in copepods, provides for the first time a set of useful polymorphic microsatellite loci for a Hemidiaptomus species, thus allowing the realization of fine-scale phylogeographic and population genetics studies of this flagship crustacean taxon for MTPs. KW - Mediterranean temporary ponds KW - diaptomid copepods KW - SSRs Y1 - 2016 U6 - https://doi.org/10.1080/11250003.2015.1126363 SN - 1125-0003 SN - 1748-5851 VL - 83 SP - 146 EP - 150 PB - Springer CY - Abingdon ER - TY - JOUR A1 - Lah, Ljerka A1 - Trense, Daronja A1 - Benke, Harald A1 - Berggren, Per A1 - Gunnlaugsson, Þorvaldur A1 - Lockyer, Christina A1 - Öztürk, Ayaka A1 - Öztürk, Bayram A1 - Pawliczka, Iwona A1 - Roos, Anna A1 - Siebert, Ursula A1 - Skóra, Krzysztof A1 - Víkingsson, Gísli A1 - Tiedemann, Ralph T1 - Spatially Explicit Analysis of Genome-Wide SNPs Detects Subtle Population Structure in a Mobile Marine Mammal, the Harbor Porpoise JF - PLoS one N2 - The population structure of the highly mobile marine mammal, the harbor porpoise (Phocoena phocoena), in the Atlantic shelf waters follows a pattern of significant isolation-by-distance. The population structure of harbor porpoises from the Baltic Sea, which is connected with the North Sea through a series of basins separated by shallow underwater ridges, however, is more complex. Here, we investigated the population differentiation of harbor porpoises in European Seas with a special focus on the Baltic Sea and adjacent waters, using a population genomics approach. We used 2872 single nucleotide polymorphisms (SNPs), derived from double digest restriction-site associated DNA sequencing (ddRAD-seq), as well as 13 microsatellite loci and mitochondrial haplotypes for the same set of individuals. Spatial principal components analysis (sPCA), and Bayesian clustering on a subset of SNPs suggest three main groupings at the level of all studied regions: the Black Sea, the North Atlantic, and the Baltic Sea. Furthermore, we observed a distinct separation of the North Sea harbor porpoises from the Baltic Sea populations, and identified splits between porpoise populations within the Baltic Sea. We observed a notable distinction between the Belt Sea and the Inner Baltic Sea sub-regions. Improved delineation of harbor porpoise population assignments for the Baltic based on genomic evidence is important for conservation management of this endangered cetacean in threatened habitats, particularly in the Baltic Sea proper. In addition, we show that SNPs outperform microsatellite markers and demonstrate the utility of RAD-tags from a relatively small, opportunistically sampled cetacean sample set for population diversity and divergence analysis. Y1 - 2016 U6 - https://doi.org/10.1371/journal.pone.0162792 SN - 1932-6203 VL - 11 IS - 10 PB - PLoS CY - Lawrence, Kan. ER -