TY - JOUR A1 - Chen, Xuhui A1 - Pohl, Martin A1 - Böttcher, Markus T1 - Particle diffusion and localized acceleration in inhomogeneous AGN jets - I. Steady-state spectra JF - Monthly notices of the Royal Astronomical Society N2 - We study the acceleration, transport, and emission of particles in relativistic jets. Localized stochastic particle acceleration, spatial diffusion, and synchrotron as well as synchrotron self-Compton (SSC) emission are considered in a leptonic model. To account for inhomogeneity, we use a 2D axisymmetric cylindrical geometry for both relativistic electrons and magnetic field. In this first phase of our work, we focus on steady-state spectra that develop from a time-dependent model. We demonstrate that small isolated acceleration region in a much larger emission volume are sufficient to accelerate particles to high energy. Diffusive escape from these small regions provides a natural explanation for the spectral form of the jet emission. The location of the acceleration regions within the jet is found to affect the cooling break of the spectrum in this diffusive model. Diffusion-caused energy-dependent inhomogeneity in the jets predicts that the SSC spectrum is harder than the synchrotron spectrum. There can also be a spectral hardening towards the high-energy section of the synchrotron spectrum, if particle escape is relatively slow. These two spectral hardening effects indicate that the jet inhomogeneity might be a natural explanation for the unexpected hard. gamma-ray spectra observed in some blazars. KW - acceleration of particles KW - diffusion KW - radiation mechanisms: non-thermal KW - galaxies:active KW - galaxies: jets Y1 - 2015 U6 - https://doi.org/10.1093/mnras/stu2438 SN - 0035-8711 SN - 1365-2966 VL - 447 IS - 1 SP - 530 EP - 544 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Cherstvy, Andrey G. A1 - Metzler, Ralf T1 - Ergodicity breaking, ageing, and confinement in generalized diffusion processes with position and time dependent diffusivity JF - Journal of statistical mechanics: theory and experiment N2 - We study generalized anomalous diffusion processes whose diffusion coefficient D(x, t) similar to D-0x(alpha)t(beta) depends on both the position x of the test particle and the process time t. This process thus combines the features of scaled Brownian motion and heterogeneous diffusion parent processes. We compute the ensemble and time averaged mean squared displacements of this generalized diffusion process. The scaling exponent of the ensemble averaged mean squared displacement is shown to be the product of the critical exponents of the parent processes, and describes both subdiffusive and superdiffusive systems. We quantify the amplitude fluctuations of the time averaged mean squared displacement as function of the length of the time series and the lag time. In particular, we observe a weak ergodicity breaking of this generalized diffusion process: even in the long time limit the ensemble and time averaged mean squared displacements are strictly disparate. When we start to observe this process some time after its initiation we observe distinct features of ageing. We derive a universal ageing factor for the time averaged mean squared displacement containing all information on the ageing time and the measurement time. External confinement is shown to alter the magnitudes and statistics of the ensemble and time averaged mean squared displacements. KW - diffusion Y1 - 2015 U6 - https://doi.org/10.1088/1742-5468/2015/05/P05010 SN - 1742-5468 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Prokopovic, Vladimir Z. A1 - Duschl, Claus A1 - Volodkin, Dmitry T1 - Hyaluronic Acid/Poly-l-Lysine Multilayers as Reservoirs for Storage and Release of Small Charged Molecules JF - Macromolecular bioscience N2 - Polyelectrolyte multilayer films are nowadays very attractive for bioapplications due to their tunable properties and ability to control cellular response. Here we demonstrate that multilayers made of hyaluronic acid and poly-l-lysine act as high-capacity reservoirs for small charged molecules. Strong accumulation within the film is explained by electrostatically driven binding to free charges of polyelectrolytes. Binding and release mechanisms are discussed based on charge balance and polymer dynamics in the film. Our results show that transport of molecules through the film-solution interface limits the release rate. The multilayers might serve as an effective platform for drug delivery and tissue engineering due to high potential for drug loading and controlled release. KW - diffusion KW - drug delivery KW - dye KW - release mechanism Y1 - 2015 U6 - https://doi.org/10.1002/mabi.201500093 SN - 1616-5187 SN - 1616-5195 VL - 15 IS - 10 SP - 1357 EP - 1363 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Shin, Jaeoh A1 - Cherstvy, Andrey G. A1 - Kim, Won Kyu A1 - Metzler, Ralf T1 - Facilitation of polymer looping and giant polymer diffusivity in crowded solutions of active particles JF - New journal of physics : the open-access journal for physics N2 - We study the dynamics of polymer chains in a bath of self-propelled particles (SPP) by extensive Langevin dynamics simulations in a two-dimensional model system. Specifically, we analyse the polymer looping properties versus the SPP activity and investigate how the presence of the active particles alters the chain conformational statistics. We find that SPPs tend to extend flexible polymer chains, while they rather compactify stiffer semiflexible polymers, in agreement with previous results. Here we show that higher activities of SPPs yield a higher effective temperature of the bath and thus facilitate the looping kinetics of a passive polymer chain. We explicitly compute the looping probability and looping time in a wide range of the model parameters. We also analyse the motion of a monomeric tracer particle and the polymer's centre of mass in the presence of the active particles in terms of the time averaged mean squared displacement, revealing a giant diffusivity enhancement for the polymer chain via SPP pooling. Our results are applicable to rationalising the dimensions and looping kinetics of biopolymers at constantly fluctuating and often actively driven conditions inside biological cells or in suspensions of active colloidal particles or bacteria cells. KW - diffusion KW - active transport KW - polymers Y1 - 2015 U6 - https://doi.org/10.1088/1367-2630/17/11/113008 SN - 1367-2630 VL - 17 PB - IOP Publ. Ltd. CY - Bristol ER - TY - BOOK A1 - Schmiedgen, Jan A1 - Rhinow, Holger A1 - Köppen, Eva A1 - Meinel, Christoph T1 - Parts without a whole? BT - The current state of Design Thinking practice in organizations N2 - This explorative study gives a descriptive overview of what organizations do and experience when they say they practice design thinking. It looks at how the concept has been appropriated in organizations and also describes patterns of design thinking adoption. The authors use a mixed-method research design fed by two sources: questionnaire data and semi-structured personal expert interviews. The study proceeds in six parts: (1) design thinking¹s entry points into organizations; (2) understandings of the descriptor; (3) its fields of application and organizational localization; (4) its perceived impact; (5) reasons for its discontinuation or failure; and (6) attempts to measure its success. In conclusion the report challenges managers to be more conscious of their current design thinking practice. The authors suggest a co-evolution of the concept¹s introduction with innovation capability building and the respective changes in leadership approaches. It is argued that this might help in unfolding design thinking¹s hidden potentials as well as preventing unintended side-effects such as discontented teams or the dwindling authority of managers. N2 - Diese explorative Studie gibt einen deskriptiven Überblick, was Organisationen tun und zu erleben, wenn sie sagen, sie üben Design Thinking. Es untersucht, wie das Konzept in Organisationen angeeignet und beschreibt auch Muster der Design Thinking Annahme. Die Autoren verwenden eine von zwei Quellen gespeist Mixed-Verfahren Forschungsdesign: Fragebogendaten und semi-strukturierten persönlichen Experteninterviews. Die Studie läuft in sechs Teile: Einstiegspunkte (1) Design-Denken in Organisationen; (2) Verständnis des Deskriptors; (3) ihre Anwendungsgebiete und organisatorische Lokalisierung;(4) dessen empfundenen Auswirkungen; (5) Gründe für ihre Einstellung oder Misserfolg; und (6) versucht, den Erfolg zu messen. Abschließend fordert der Bericht-Manager mehr bewusst ihre aktuellen Design Thinking der Praxis zu sein. Die Autoren schlagen eine Ko-Evolution von Einführung des Konzepts mit Innovationsfähigkeit Gebäude und den jeweiligen Führungswechsel Ansätze. Es wird argumentiert, dass dies in der Entfaltung versteckte Potentiale Design Denken wie auch zur Verhinderung unbeabsichtigten Nebenwirkungen, wie unzufrieden Teams oder die schwindende Autorität von Managern zu helfen. T3 - Technische Berichte des Hasso-Plattner-Instituts für Digital Engineering an der Universität Potsdam - 97 KW - design thinking KW - innovation KW - innovation management KW - innovation capabilities KW - organizational change KW - change management KW - management KW - adoption KW - diffusion KW - study KW - leadership KW - Design Thinking KW - Innovation KW - Innovationsmanagement KW - Organisationsveränderung KW - Change Management KW - Management KW - Innovationsmethode KW - Studie KW - Leadership Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-79969 SN - 978-3-86956-334-3 SN - 1613-5652 SN - 2191-1665 IS - 97 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - THES A1 - Ansel, Simon T1 - Die Diffusion von Innovationen in deutschen Kommunen T1 - Diffusion of e-government at the local level BT - eine Untersuchung zu Komponenten des E-Governement BT - empirical evidence from German municipalities N2 - Die fortschreitende Diffusion von E-Government ist ein Phänomen, dem in der internationa-len Forschungsliteratur bereits viel Aufmerksamkeit zu Teil wurde. Erstaunlich wenige Studien widmen sich bislang jedoch dezidiert dem Faktor Interdependenz, der eigentlichen Ursache von Diffusionsprozessen. In dieser Arbeit werden Interdependenzbeziehungen anhand dreier spezifischer Mechanismen der Diffusion, namentlich „Nachahmung“, „Wettbewerb“ und „Lernen“, untersucht. Auf Basis einer empirischen Analyse mit Daten zur Einführung von E-Government-Komponenten in 183 deutschen Städten über den Zeitraum von 1995 bis 2014 konnte ein Einfluss der Mechanismen „Nachahmung“ und „Lernen“ auf das Innovationsverhalten von Kommunen festgestellt werden. Für das Vorliegen von Wettbe-werbsdynamiken ließen sich demgegenüber keine Anhaltspunkte finden. Für zukünftige Forschungen zur Diffusion von Innovationen wird angeregt, verstärkt an die mechanismen- und prozessbasierte Perspektive von Diffusion als theoretischem Rahmenkonzept anzuknüpfen. N2 - The ongoing diffusion of e-government is a phenomenon that has already attracted consid-erable attention in the international research literature. However, few studies have so far focused on the factor of interdependence, the root cause of diffusion processes. This paper deals with interdependence by specifying three causal mechanisms of diffusion, namely "imitation", "competition" and "learning". Drawing upon data collected on the introduction of e-government in 183 German cities over the period from 1995-2014, the empirical analysis identified "imitation" and "learning" as predictors of municipal innovative behavior. Furthermore, no evidence was found supporting the role of “competition”. With regard to future research on innovation diffusion, it is suggested to incorporate the mechanism- and process-based perspective of diffusion as a theoretical framework. T3 - Schriftenreihe für Public und Nonprofit Management - 20 KW - Diffusion KW - E-Government KW - eGovernment KW - öffentlicher Sektor KW - Kommune KW - kommunal KW - diffusion KW - e-government KW - electronic government KW - public sector KW - local KW - municipal KW - Nachahmung KW - Wettbewerb KW - Lernen KW - imitation KW - competition KW - learning Y1 - 2015 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-80370 SN - 2190-4561 ER -