TY - JOUR A1 - Yenesew, Abiy A1 - Twinomuhwezi, Hannington A1 - Kiremire, Bernard T. A1 - Mbugua, Martin N. A1 - Gitu, Peter M. A1 - Heydenreich, Matthias A1 - Peter, Martin G. T1 - 8-Methoxyneorautenol and radical scavenging flavonoids from Erythrina abyssinica N2 - A new pterocarpan (named 8-methoxyneorautenol) was isolated from the acetone ext. of the root bark of Erythrina abyssinica. In addn., the known isoflavonoid derivs. eryvarin L, erycristagallin and shinpterocarpin were identified for the first time from the roots of this plant. The structures were detd. on the basis of spectroscopic evidence. The new compd. showed selective antimicrobial activity against Trichophyton mentagrophytes. The acetone ext. of the root bark of E. abyssinica showed radical scavenging activity towards 2,2-diphenyl-1-picrylhydrazyl radical (DPPH). The pterocarpenes, 3-hydroxy-9-methoxy-10-(3,3-dimethylallyl)pterocarpene and erycristagallin, were the most active constituents of the roots of this plant and showing dose-dependent activities similar to that of the std. quercetin. [on SciFinder (R)] Y1 - 2009 UR - http://www.ajol.info/journal_index.php?jid=120&ab=bcse SN - 1011-3924 ER - TY - JOUR A1 - Fettke, Anja A1 - Peikow, Dirk A1 - Peter, Martin G. A1 - Kleinpeter, Erich T1 - Synthesis and conformational analysis of glycomimetic analogs of thiochitobiose N2 - The synthesis of six analogs of N,N;-diacetylchitobiose is reported, including a novel transglycosylation reaction for the preparation of S-aryl thioglycosides. The conformations of the compounds were studied by a combination of NMR spectroscopy and molecular modeling, using force field calculations. In the case of the S-aryl thioglycosides with exclusively S-glycosidic linkages, dihedral angles of the disaccharidic S-glycosidic bonds, ;; and ;; and of the S-arylglycoside bonds, ; and ;, were found to be similar, whereas they were different in mixed glycosides and in a thiazoline derivative. An adequate correlation between the calculated H,H-distances of the local minima and the measured NOE contacts was achieved by applying population-weighted averages over participating conformers based on weighted relative energies. Y1 - 2009 UR - http://www.sciencedirect.com/science/journal/00404020 U6 - https://doi.org/10.1016/j.tet.2009.03.067 SN - 0040-4020 ER - TY - JOUR A1 - Menezes, Bruno M. A1 - Grigolon, Lisanne A1 - Todorovic, Zoran A1 - Peter, Martin G. A1 - Franco, Telma T. T1 - On the depolymerization of chitosan by papain : a re-assessment Y1 - 2009 ER - TY - JOUR A1 - Issaree, Arisara A1 - Vijayakrishnan, Balakumar A1 - Abdelnur, Patricia V. A1 - Corilo, Yuri E. A1 - Riccio, Maria F. A1 - Sanvido, Gustavo B. A1 - Eberlin, Marcos N. A1 - Peter, Martin G. T1 - Mass spectrometry of aminoglucan oligosaccharides using electrospray ionization MS/MS and MS/MS/MS Y1 - 2009 ER - TY - GEN A1 - Peter, Martin G. A1 - Yenesew, Abiy A1 - Twinomuhwezi, Hannington A1 - Kabaru, Jacques M. A1 - Akala, Hoseah M. A1 - Kiremire, Bernard T. A1 - Heydenreich, Matthias A1 - Eyase, Fredrick A1 - Waters, Norman C. A1 - Walsh, Douglas S. T1 - Antiplasmodial and larvicidal flavonoids from Derris trifoliata N2 - From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquineresistant) strains of Plasmodium falciparum. The different parts of this plant showed larvicidal activities against Aedes aegypti and rotenoids were identified as the active principles. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 121 KW - Derris trifoliata KW - Leguminosae KW - Flavanone KW - (S)-Lupinifolin 4´-methyl ether KW - Lupinifolin Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44614 ER - TY - GEN A1 - Peter, Martin G. A1 - Muiva, Lois M. A1 - Yenesew, Abiy A1 - Derese, Solomon A1 - Heydenreich, Matthias A1 - Akala, Hoseah M. A1 - Eyase, Fredrick A1 - Waters, Norman C. A1 - Mutai, Charles A1 - Keriko, Joseph M. A1 - Walsh, Douglas S. T1 - Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata N2 - From the seedpods of Tephrosia elata, a new β-hydroxydihydrochalcone named (S)-elatadihydrochalcone was isolated. In addition, the known flavonoids obovatachalcone, obovatin, obovatin methyl ether and deguelin were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids obtained from the seedpods of this plant showed antiplasmodial activities. The literature NMR data on β-hydroxydihydrochalcones is reviewed and the identity of some of the compounds assigned β-hydroxydihydrochalcone skeleton is questioned. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 118 KW - Tephrosia elata KW - Leguminosae KW - Seedpods KW - (S)-Elatadihydrochalcone KW - β-Hydroxydihydrochalcone Y1 - 2009 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44437 ER -