TY  - JOUR
A1  - Kovach, Ildyko
A1  - Kosmella, Sabine
A1  - Prietzel, Claudia Christina
A1  - Bagdahn, Christian
A1  - Koetz, Joachim
T1  - Nano-porous calcium phosphate balls
JF  - Colloids and surfaces : an international journal devoted to fundamental and applied research on colloid and interfacial phenomena in relation to systems of biological origin ; B, Biointerfaces
N2  - By dropping a NaH2PO4 center dot H2O precursor solution to a CaCl2 solution at 90 degrees C under continuous stirring in presence of two biopolymers, i.e. gelatin (G) and chitosan (C), supramolecular calcium phosphate (CP) card house structures are formed. Light microscopic investigations in combination with scanning electron microscopy show that the GC-based flower-like structure is constructed from very thin CP platelets. Titration experiments indicate that H-bonding between both biopolymers is responsible for the synergistic effect in presence of both polymers. Gelatin chitosan water complexes play an important role with regard to supramolecular ordering. FTIR spectra in combination with powder X-ray diffraction show that after burning off all organic components (heating up >600 degrees C) dicalcium and tricalcium phosphate crystallites are formed. From high resolution transmission electron microscopy (HR-TEM) it is obvious to conclude, that individual crystal platelets are dicalcium phosphates, which build up ball-like supramolecular structures. The results reveal that the GC guided crystal growth leads to nano-porous supramolecular structures, potentially attractive candidates for bone repair. (c) 2015 Elsevier B.V. All rights reserved.
KW  - Calcium phosphates
KW  - Bone repair material
KW  - Biomineralization
KW  - Supramolecular ball structure
Y1  - 2015
U6  - https://doi.org/10.1016/j.colsurfb.2015.05.021
SN  - 0927-7765
SN  - 1873-4367
VL  - 132
SP  - 246
EP  - 252
PB  - Elsevier
CY  - Amsterdam
ER  -