TY  - JOUR
A1  - Schneider, Matthias
A1  - Günter, Christina
A1  - Taubert, Andreas
T1  - Co-deposition of a hydrogel/calcium phosphate hybrid layer on 3D printed poly(lactic acid) scaffolds via dip coating
BT  - Towards Automated Biomaterials Fabrication
JF  - Polymers
N2  - The article describes the surface modification of 3D printed poly(lactic acid) (PLA) scaffolds with calcium phosphate (CP)/gelatin and CP/chitosan hybrid coating layers. The presence of gelatin or chitosan significantly enhances CP co-deposition and adhesion of the mineral layer on the PLA scaffolds. The hydrogel/CP coating layers are fairly thick and the mineral is a mixture of brushite, octacalcium phosphate, and hydroxyapatite. Mineral formation is uniform throughout the printed architectures and all steps (printing, hydrogel deposition, and mineralization) are in principle amenable to automatization. Overall, the process reported here therefore has a high application potential for the controlled synthesis of biomimetic coatings on polymeric biomaterials.
KW  - 3D printing
KW  - dip-coating
KW  - poly(lactic acid)
KW  - PLA
KW  - calcium phosphate
KW  - gelatin
KW  - chitosan
KW  - hydrogel
KW  - calcium phosphate hybrid material
KW  - biomaterials
Y1  - 2018
U6  - https://doi.org/10.3390/polym10030275
SN  - 2073-4360
VL  - 10
IS  - 3
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Salama, Ahmed
A1  - Neumann, Mike
A1  - Günter, Christina
A1  - Taubert, Andreas
T1  - Ionic liquid-assisted formation of cellulose/calcium phosphate hybrid materials
JF  - Beilstein journal of nanotechnology
N2  - Cellulose/calcium phosphate hybrid materials were synthesized via an ionic liquid-assisted route. Scanning electron microscopy, transmission electron microscopy, energy-dispersive X-ray spectroscopy, X-ray diffraction, infrared spectroscopy, and thermogravimetric analysis/differential thermal analysis show that, depending on the reaction conditions, cellulose/hydroxyapatite, cellulose/ chlorapatite, or cellulose/monetite composites form. Preliminary studies with MC3T3-E1 pre-osteoblasts show that the cells proliferate on the hybrid materials suggesting that the ionic liquid-based process yields materials that are potentially useful as scaffolds for regenerative therapies.
KW  - biomineralization
KW  - calcium phosphate
KW  - carbohydrates
KW  - cellulose
KW  - hybrid materials
KW  - ionic liquid
Y1  - 2014
U6  - https://doi.org/10.3762/bjnano.5.167
SN  - 2190-4286
VL  - 5
SP  - 1553
EP  - 1568
PB  - Beilstein-Institut zur Förderung der Chemischen Wissenschaften
CY  - Frankfurt, Main
ER  -