TY  - JOUR
A1  - Gupta, Banshi D.
A1  - Pathak, Anisha
A1  - Shrivastav, Anand
T1  - Optical Biomedical Diagnostics Using Lab-on-Fiber Technology
BT  - a review
JF  - Photonics : open access journal
N2  - Point-of-care and in-vivo bio-diagnostic tools are the current need for the present critical scenarios in the healthcare industry. The past few decades have seen a surge in research activities related to solving the challenges associated with precise on-site bio-sensing. Cutting-edge fiber optic technology enables the interaction of light with functionalized fiber surfaces at remote locations to develop a novel, miniaturized and cost-effective lab on fiber technology for bio-sensing applications. The recent remarkable developments in the field of nanotechnology provide innumerable functionalization methodologies to develop selective bio-recognition elements for label free biosensors. These exceptional methods may be easily integrated with fiber surfaces to provide highly selective light-matter interaction depending on various transduction mechanisms. In the present review, an overview of optical fiber-based biosensors has been provided with focus on physical principles used, along with the functionalization protocols for the detection of various biological analytes to diagnose the disease. The design and performance of these biosensors in terms of operating range, selectivity, response time and limit of detection have been discussed. In the concluding remarks, the challenges associated with these biosensors and the improvement required to develop handheld devices to enable direct target detection have been highlighted.
KW  - fiber optic sensors
KW  - synthesis
KW  - interferometry
KW  - fluorescence
KW  - SERS
KW  - SPR
KW  - immunosensors
KW  - enzymatic sensors
KW  - molecular imprinted polymers
Y1  - 2022
U6  - https://doi.org/10.3390/photonics9020086
SN  - 2304-6732
VL  - 9
IS  - 2
PB  - MDPI
CY  - Basel
ER  - 
TY  - JOUR
A1  - Gahlaut, Shashank K.
A1  - Pathak, Anisha
A1  - Gupta, Banshi D.
T1  - Recent advances in silver nanostructured substrates for plasmonic sensors
JF  - Biosensors : open access journal
N2  - Noble metal nanostructures are known to confine photon energies to their dimensions with resonant oscillations of their conduction electrons, leading to the ultrahigh enhancement of electromagnetic fields in numerous spectroscopic methods. 
Of all the possible plasmonic nanomaterials, silver offers the most intriguing properties, such as best field enhancements and tunable resonances in visible-to-near infrared regions. 
This review highlights the recent developments in silver nanostructured substrates for plasmonic sensing with the main emphasis on surface plasmon resonance (SPR) and surface-enhanced Raman spectroscopy (SERS) over the past decade. 
The main focus is on the synthesis of silver nanostructured substrates via physical vapor deposition and chemical synthesis routes and their applications in each sensing regime. 
A comprehensive review of recent literature on various possible silver nanostructures prepared through these methodologies is discussed and critically reviewed for various planar and optical fiber-based substrates.
KW  - silver
KW  - plasmonics
KW  - sensors
KW  - surface-enhanced Raman spectroscopy
KW  - surface-enhanced fluorescence
KW  - surface-enhanced infrared spectroscopy
Y1  - 2022
U6  - https://doi.org/10.3390/bios12090713
SN  - 2079-6374
VL  - 12
IS  - 9
PB  - MDPI
CY  - Basel
ER  -