TY  - JOUR
A1  - Mirskova, Anna N.
A1  - Adamovich, Sergey N.
A1  - Mirskov, Rudolf G.
A1  - Kolesnikova, Olga P.
A1  - Schilde, Uwe
T1  - Immunoactive ionic liquids based on 2-hydroxyethylamines and 1-R-indol-3-ylsulfanylacetic acids. Crystal and molecular structure of immunodepressant tris-(2-hydroxyethyl)ammonium indol-3-ylsulfanylacetate
JF  - Open chemistry : formerly Central European journal of chemistry
N2  - Immunoactive ionic liquids (2-hydroxyethyl) ammonium 1-R-indol-3-ylsulfanyl-acetates HN+R1R2(CH2CH2OH)center dot O-(O)CCH2S-Ind-R-3-1(1-5), were synthesized by the reaction of (2-hydroxyethyl)amines with indol-3-ylsulfanylacetic- or 1-benzylindol-3-ylsulfanylacetic acid. 1: R-1 = R-2 = CH2CH2OH, R-3 = H; 2: R-1 =CH3, R-2=CH2CH2OH, R3 = H; 3: R-1 = R-2 = CH3, R-3 = H; 4: R-1 = R-2 = CH2CH2OH, R-3 = CH2C6H5; 5: R-1 = CH3; R-2 = CH2CH2OH; R-3 = CH2C6H5. The structure of each compound was elucidated by IR, NMR H-1, C-13, and N-15 techniques and their composition was confirmed by elemental analysis. The crystal structure of tris-(2-hydroxyethyl) ammonium indol-3-ylsulfanylacetate was investigated by X-ray diffraction analysis. Immunoactive properties of the title compounds were screened.
KW  - Protic 2-hydroxyethylammonium ionic liquids
KW  - 2-Hydroxyethylammonium 1-R-indol-3-ylsulfanylacetates
KW  - Crystal and molecular structure
KW  - Immunoactive properties
Y1  - 2015
U6  - https://doi.org/10.1515/chem-2015-0018
SN  - 2391-5420
VL  - 13
IS  - 1
SP  - 149
EP  - 155
PB  - De Gruyter Open
CY  - Warsaw
ER  - 
TY  - JOUR
A1  - Adamovich, Sergey N.
A1  - Mirskova, Anna N.
A1  - Mirskov, Rudolf G.
A1  - Schilde, Uwe
T1  - Synthesis and crystal structure of 1,4,10,13-tetraoxa-7,16-diazoniumcyclo-octadecane bis(4-chloro-2-methyl-phenoxyacetate)
JF  - Chemistry central journal
N2  - The title compound was prepared by the reaction of 1,4,10,13-tetraoxa-7,16-diazacyclo-octadecane with 4-chloro-2-methyl-phenoxyacetic acid in a ratio of 1:2. The structure has been proved by the data of elemental analysis, IR spectroscopy, NMR ((1)H, (13)C) technique and by X-ray diffraction analysis. Intermolecular hydrogen bonds between the azonium protons and oxygen atoms of the carboxylate groups were found. Immunoactive properties of the title compound have been screened. The compound has the ability to suppress spontaneous and Con A-stimulated cell proliferation in vitro and therefore can be considered as immunodepressant.
Y1  - 2011
U6  - https://doi.org/10.1186/1752-153X-5-23
SN  - 1752-153X
VL  - 5
IS  - 17
PB  - BioMed Central
CY  - London
ER  -