TY - THES A1 - Geißler, Daniel T1 - Multiplexing in homogenen FRET-Immunoassays : Detektion von Lungenkrebs-Tumormarkern mittels zeitaufgelöster Laserspektoskopie durch Förster-Resonanzenergietransfer (FRET) Y1 - 2012 CY - Potsdam ER - TY - JOUR A1 - Geißler, Daniel A1 - Charbonnière, Loïc J. A1 - Ziessel, Raymond F. A1 - Butlin, Nathaniel G. A1 - Löhmannsröben, Hans-Gerd A1 - Hildebrandt, Niko T1 - Quantum dot biosensors for ultrasensitive multiplexed diagnostics N2 - Time- and color-resolved detection of Foerster resonance energy transfer (FRET) from luminescent terbium complexes to different semiconductor quantum dots results in a fivefold multiplexed bioassay with sub-picomolar detection limits for all five bioanalytes (see picture). The detection of up to five biomarkers occurs with a sensitivity that is 40-240-fold higher than one of the best-established single-analyte reference assays. Y1 - 2010 UR - http://www3.interscience.wiley.com/cgi-bin/jhome/26737/ U6 - https://doi.org/10.1002/anie.200906399 SN - 1433-7851 ER - TY - JOUR A1 - Geißler, Daniel A1 - Charbonnière, Loïc J. A1 - Ziessel, Raymond F. A1 - Löhmannsröben, Hans-Gerd T1 - Quantum dots as FRET acceptors for highly sensitive multiplexing immunoassays Y1 - 2009 ER - TY - JOUR A1 - Geißler, Daniel A1 - Butlin, Nathaniel G. A1 - Hill, Diana A1 - Löhmannsröben, Hans-Gerd A1 - Hildebrandt, Niko T1 - Multiplexed diagnostics and spectroscopic ruler applications with terbium to quantum dots FRET Y1 - 2008 SN - 1605-7422 ER -