TY - JOUR A1 - Oosthoek, Kris A1 - Doerr, Christian T1 - Cyber threat intelligence: A product without a process? JF - International journal of intelligence and counterintelligence Y1 - 2020 U6 - https://doi.org/10.1080/08850607.2020.1780062 SN - 0885-0607 SN - 1521-0561 VL - 34 IS - 2 SP - 300 EP - 315 PB - Taylor & Francis CY - London ER - TY - JOUR A1 - Klaus, Susanne A1 - Ost, Mario T1 - Mitochondrial uncoupling and longevity BT - a role for mitokines? JF - Experimental gerontology N2 - Aging has been viewed both as a random process due to accumulation of molecular and cellular damage over time and as a programmed process linked to cellular pathway important for growth and maturation. These views converge on mitochondria as both the major producer of damaging reactive oxidant species (ROS) and as signaling organelles. A finite proton leak across the inner mitochondrial membrane leading to a slight uncoupling of oxidative phosphorylation and respiration is an intrinsic property of all mitochondria and according to the "uncoupling to survive" hypothesis it has evolved to protect against ROS production to minimize oxidative damage. This hypothesis is supported by evidence linking an increased endogenous, uncoupling protein (UCP1) mediated, as well as experimentally induced mitochondrial uncoupling to an increased lifespan in rodents. This is possibly due to the synergistic activation of molecular pathways linked to life extending effects of caloric restriction as well as a mitohormetic response. Mitohormesis is an adaptive stress response through mitonuclear signaling which increases stress resistance resulting in health promoting effects. Part of this response is the induction of fibroblast growth factor 21 (FGF21) and growth and differentiation factor 15 (GDF15), two stress-induced mitokines which elicit beneficial systemic metabolic effects via endocrine action. KW - Uncoupling proteins KW - Energy metabolism KW - Skeletal muscle KW - Mitohormesis KW - GDF15 KW - FGF21 Y1 - 2019 U6 - https://doi.org/10.1016/j.exger.2019.110796 SN - 0531-5565 SN - 1873-6815 VL - 130 PB - Elsevier Science CY - Amsterdam ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Rezension zu: Brenner, Michael: Der lange Schatten der Revolution : Juden und Antisemiten in Hitlers München 1918 bis 1923. - Berlin: Jüdischer Verlag im Suhrkamp Verlag, 2019. - 300 S. - ISBN 978-3-633-54295-6 JF - Quest : issues in contemporary Jewish history Y1 - 2020 U6 - https://doi.org/10.48248/issn.2037-741X/1842 SN - 2037-741X IS - 17 SP - 222 EP - 225 PB - Fondazione Centro di Documentazione Ebraica Contemporanea CY - Milano ER - TY - JOUR A1 - Krah, Markus T1 - Rezension zu: Mihăilescu, Dana: Eastern European Jewish American narratives, 1890-1930 : struggles for recognition. - Lanham: Lexington Books, 2018. - XXi, 249 S. - ISBN: 978-1-4985-6389-5 JF - American Jewish history : an American Jewish Historical Society quarterly publication Y1 - 2020 U6 - https://doi.org/10.1353/ajh.2020.0039 SN - 0164-0178 SN - 1086-3141 VL - 104 IS - 2-3 SP - 469 EP - 471 PB - Johns Hopkins Univ. Press CY - Baltimore, MD ER - TY - JOUR A1 - Schultze, Sven T1 - Rezension zu: Tenorth, Heinz-Elmar: Wilhelm von Humboldt: Bildungspolitik und Universitätsreform. - Paderborn: Ferdinand Schöningh, 2018. 262 S. - ISBN: 978-3-5067-888-0 JF - Isis : an international review devoted to the history of science and its cultural influences Y1 - 2020 U6 - https://doi.org/10.1086/707858 SN - 0021-1753 SN - 1545-6994 VL - 111 IS - 1 SP - 179 EP - 180 PB - Univ. of Chicago Press CY - Chicago ER - TY - JOUR A1 - Haag, Johannes T1 - Rezension zu: Willascheck, Marcus: Kant on the sources of metaphysics: the dialectic of pure reason. - New York: Cambridge University Press, 2018, 298pp. - ISBN: 978-1-108-47263-0 JF - European journal of philosophy Y1 - 2020 U6 - https://doi.org/10.1111/ejop.12555 SN - 0966-8373 SN - 1468-0378 VL - 28 IS - 2 SP - 524 EP - 528 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Fuhr, Harald T1 - Rezension zu: Geopolitical economy of energy and anvironment : China and the European Union / Hrsg.: Amineh, Mehdi Parvizi ; Yang, Guang. - Leiden: Brill, 2017. - ISBN: 978-90-04-27310-8 JF - Comparative sociology Y1 - 2020 U6 - https://doi.org/10.1163/15691330-12341522 SN - 1569-1322 SN - 1569-1330 VL - 19 IS - 1 SP - 151 EP - 153 PB - Brill CY - Leiden ER - TY - JOUR A1 - Godess-Riccitelli, Moran T1 - Rezension zu: Chaouli, Michel: Thinking with Kant's Critique of Judgment. - Cambridge, MA: Harvard University Press, 2017. - Pp. 315. - ISBN: 978-0-67497136-3 JF - Kantian review Y1 - 2020 U6 - https://doi.org/10.1017/S1369415420000102 SN - 1369-4154 SN - 2044-2394 VL - 25 IS - 2 SP - 313 EP - 317 PB - Cambridge Univ. Press CY - Cambridge ER - TY - JOUR A1 - Borýsek, Martin T1 - Rezension zu: Lauer, Rena N.: Colonial justice and the Jews of Venetian Crete. - Philadelphia : University of Pennsylvania Press, 2019. - X, 292 S. - ISBN: 978-0-8122-5088-6 (The Middle ages series) JF - The journal of interdisciplinary history Y1 - 2020 U6 - https://doi.org/10.1162/jinh_r_01572 SN - 0022-1953 SN - 1530-9169 VL - 51 IS - 2 SP - 323 EP - 325 PB - MIT Press CY - Cambridge ER - TY - JOUR A1 - Kabeshkin, Anton T1 - Rezension zu: Órdenes, Paula ; Pickhan, Anna (eds).: Teleologische Reflexion in Kants Philosophie. - Wiesbaden: Springer, 2019. - ISBN 978-3-658-23693-9 JF - Kantian review Y1 - 2020 U6 - https://doi.org/10.1017/S1369415420000217 SN - 1369-4154 SN - 2044-2394 VL - 25 IS - 3 SP - 508 EP - 513 PB - Cambridge University Press CY - Cambridge ER - TY - JOUR A1 - Metzler, Ralf T1 - Superstatistics and non-Gaussian diffusion JF - The European physical journal special topics N2 - Brownian motion and viscoelastic anomalous diffusion in homogeneous environments are intrinsically Gaussian processes. In a growing number of systems, however, non-Gaussian displacement distributions of these processes are being reported. The physical cause of the non-Gaussianity is typically seen in different forms of disorder. These include, for instance, imperfect "ensembles" of tracer particles, the presence of local variations of the tracer mobility in heteroegenous environments, or cases in which the speed or persistence of moving nematodes or cells are distributed. From a theoretical point of view stochastic descriptions based on distributed ("superstatistical") transport coefficients as well as time-dependent generalisations based on stochastic transport parameters with built-in finite correlation time are invoked. After a brief review of the history of Brownian motion and the famed Gaussian displacement distribution, we here provide a brief introduction to the phenomenon of non-Gaussianity and the stochastic modelling in terms of superstatistical and diffusing-diffusivity approaches. KW - Brownian diffusion KW - anomalous diffusion KW - dynamics KW - kinetic-theory KW - models KW - motion KW - nanoparticles KW - nonergodicity KW - statistics KW - subdiffusion Y1 - 2020 U6 - https://doi.org/10.1140/epjst/e2020-900210-x SN - 1951-6355 SN - 1951-6401 VL - 229 IS - 5 SP - 711 EP - 728 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Yarman, Aysu A1 - Scheller, Frieder W. T1 - How reliable is the electrochemical readout of MIP sensors? JF - Sensors N2 - Electrochemical methods offer the simple characterization of the synthesis of molecularly imprinted polymers (MIPs) and the readouts of target binding. The binding of electroinactive analytes can be detected indirectly by their modulating effect on the diffusional permeability of a redox marker through thin MIP films. However, this process generates an overall signal, which may include nonspecific interactions with the nonimprinted surface and adsorption at the electrode surface in addition to (specific) binding to the cavities. Redox-active low-molecular-weight targets and metalloproteins enable a more specific direct quantification of their binding to MIPs by measuring the faradaic current. The in situ characterization of enzymes, MIP-based mimics of redox enzymes or enzyme-labeled targets, is based on the indication of an electroactive product. This approach allows the determination of both the activity of the bio(mimetic) catalyst and of the substrate concentration. KW - molecularly imprinted polymers KW - electropolymerization KW - direct electron KW - transfer KW - catalysis KW - redox marker KW - gate effect Y1 - 2020 U6 - https://doi.org/10.3390/s20092677 SN - 1424-8220 VL - 20 IS - 9 PB - MDPI CY - Basel ER - TY - JOUR A1 - Putri, Christiani Dwi A1 - Das, Avantika T1 - Review of: Sanders, Rob: Pride: the story of Harvey Milk and the rainbow flag. - New York : Random House USA, 2018. - 48 S.- ISBN 978-0-399-55531-2 JF - Journal of language & literacy education : JoLLE Y1 - 2020 SN - 1559-9035 VL - 16 IS - 1 SP - 1 EP - 2 PB - Univ. Georgia CY - Athens, Ga. ER - TY - JOUR A1 - Rauschenbach, Sina T1 - Rezension zu: Totzeck, Markus M.: Die politischen Gesetze des Mose. Entstehung und Einflüsse der politia-judaica-Literatur in der Frühen Neuzeit. - Göttingen: Vandenhoeck & Ruprecht, 2019. - ISBN 978-3-525-57073-9 JF - Grotiana Y1 - 2020 U6 - https://doi.org/10.1163/18760759-04101013 SN - 0167-3831 SN - 1876-0759 VL - 41 IS - 1 SP - 251 EP - 254 PB - Brill CY - Leiden ER - TY - JOUR A1 - Leimkühler, Silke T1 - The biosynthesis of the molybdenum cofactors in Escherichia coli JF - Environmental microbiology N2 - The biosynthesis of the molybdenum cofactor (Moco) is highly conserved among all kingdoms of life. In all molybdoenzymes containing Moco, the molybdenum atom is coordinated to a dithiolene group present in the pterin-based 6-alkyl side chain of molybdopterin (MPT). In general, the biosynthesis of Moco can be divided into four steps in in bacteria: (i) the starting point is the formation of the cyclic pyranopterin monophosphate (cPMP) from 5 '-GTP, (ii) in the second step the two sulfur atoms are inserted into cPMP leading to the formation of MPT, (iii) in the third step the molybdenum atom is inserted into MPT to form Moco and (iv) in the fourth step bis-Mo-MPT is formed and an additional modification of Moco is possible with the attachment of a nucleotide (CMP or GMP) to the phosphate group of MPT, forming the dinucleotide variants of Moco. This review presents an update on the well-characterized Moco biosynthesis in the model organism Escherichia coli including novel discoveries from the recent years. KW - periplasmic nitrate reductase KW - biotin sulfoxide reductase KW - in-vitro-synthesis KW - n-oxide reductase KW - crystal-structure KW - molybdopterin synthase KW - formate dehydrogenase KW - rhodobacter-capsulatus KW - xanthine dehydrogenase KW - converting factor Y1 - 2020 U6 - https://doi.org/10.1111/1462-2920.15003 SN - 1462-2912 SN - 1462-2920 VL - 22 IS - 6 SP - 2007 EP - 2026 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - van Rees, Charles B. A1 - Waylen, Kerry A. A1 - Schmidt-Kloiber, Astrid A1 - Thackeray, Stephen J. A1 - Kalinkat, Gregor A1 - Martens, Koen A1 - Domisch, Sami A1 - Lillebo, Ana A1 - Hermoso, Virgilio A1 - Grossart, Hans-Peter A1 - Schinegger, Rafaela A1 - Decleer, Kris A1 - Adriaens, Tim A1 - Denys, Luc A1 - Jaric, Ivan A1 - Janse, Jan H. A1 - Monaghan, Michael T. A1 - De Wever, Aaike A1 - Geijzendorffer, Ilse A1 - Adamescu, Mihai C. A1 - Jähnig, Sonja C. T1 - Safeguarding freshwater life beyond 2020 BT - recommendations for the new global biodiversity framework from the European experience JF - Conservation letters N2 - Plans are currently being drafted for the next decade of action on biodiversity-both the post-2020 Global Biodiversity Framework of the Convention on Biological Diversity (CBD) and Biodiversity Strategy of the European Union (EU). Freshwater biodiversity is disproportionately threatened and underprioritized relative to the marine and terrestrial biota, despite supporting a richness of species and ecosystems with their own intrinsic value and providing multiple essential ecosystem services. Future policies and strategies must have a greater focus on the unique ecology of freshwater life and its multiple threats, and now is a critical time to reflect on how this may be achieved. We identify priority topics including environmental flows, water quality, invasive species, integrated water resources management, strategic conservation planning, and emerging technologies for freshwater ecosystem monitoring. We synthesize these topics with decades of first-hand experience and recent literature into 14 special recommendations for global freshwater biodiversity conservation based on the successes and setbacks of European policy, management, and research. Applying and following these recommendations will inform and enhance the ability of global and European post-2020 biodiversity agreements to halt and reverse the rapid global decline of freshwater biodiversity. KW - climate change KW - conservation KW - ecosystem services KW - rivers KW - sustainable KW - development goals KW - water resources KW - wetlands Y1 - 2020 U6 - https://doi.org/10.1111/conl.12771 SN - 1755-263X VL - 14 IS - 1 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - Barbolini, Natasha A1 - Woutersen, Amber A1 - Dupont-Nivet, Guillaume A1 - Silvestro, Daniele A1 - Tardif-Becquet, Delphine A1 - Coster, Pauline M. C. A1 - Meijer, Niels A1 - Chang, Cun A1 - Zhang, Hou-Xi A1 - Licht, Alexis A1 - Rydin, Catarina A1 - Koutsodendris, Andreas A1 - Han, Fang A1 - Rohrmann, Alexander A1 - Liu, Xiang-Jun A1 - Zhang, Y. A1 - Donnadieu, Yannick A1 - Fluteau, Frederic A1 - Ladant, Jean-Baptiste A1 - Le Hir, Guillaume A1 - Hoorn, M. Carina T1 - Cenozoic evolution of the steppe-desert biome in Central Asia JF - Science Advances N2 - The origins and development of the arid and highly seasonal steppe-desert biome in Central Asia, the largest of its kind in the world, remain largely unconstrained by existing records. It is unclear how Cenozoic climatic, geological, and biological forces, acting at diverse spatial and temporal scales, shaped Central Asian ecosystems through time. Our synthesis shows that the Central Asian steppe-desert has existed since at least Eocene times but experienced no less than two regime shifts, one at the Eocene-Oligocene Transition and one in the mid-Miocene. These shifts separated three successive "stable states," each characterized by unique floral and faunal structures. Past responses to disturbance in the Asian steppe-desert imply that modern ecosystems are unlikely to recover their present structures and diversity if forced into a new regime. This is of concern for Asian steppes today, which are being modified for human use and lost to desertification at unprecedented rates. Y1 - 2020 U6 - https://doi.org/10.1126/sciadv.abb8227 SN - 2375-2548 VL - 6 IS - 41 PB - American Association for the Advancement of Science CY - Washington ER - TY - JOUR A1 - van der Kroef, Ilona A1 - Koszinski, Sylvia A1 - Grinat, Michael A1 - van der Meij, Marijn W. A1 - Hierold, Wilfried A1 - Südekum, Wolfgang A1 - Sommer, Michael T1 - Digital mapping of buried soil horizons using 2D and pseudo-3D geoelectrical measurements in a ground moraine landscape JF - European journal of soil science : EJSS N2 - The identification of buried soil horizons in agricultural landscapes helps to quantify sediment budgets and erosion-related carbon dynamics. High-resolution mapping of buried horizons using conventional soil surveys is destructive and time consuming. Geoelectrical sensors can offer a fast and non-destructive alternative for determining horizon positions and properties. In this paper, we compare the suitability of several geoelectrical methods for measuring the depth to buried horizons (Apb, Ahb and Hab) in the hummocky ground moraine landscape of northeastern Germany. Soil profile descriptions were developed for 269 locations within a 6-ha experimental field "CarboZALF-D". A stepwise linear discriminant analysis (LDA) estimated the lateral position of the buried horizons using electromagnetic induction data and terrain attributes. To predict the depth of a buried horizon, multiple linear regression (MLR) was used for both a 120-m transect and a 0.2-ha pseudo-three-dimensional (3D) area. At these scales, apparent electrical conductivity (ECa), electrical resistivity (ER) and terrain attributes were used as independent variables. The LDA accurately predicted Apb- and Ahb-horizons (a correct classification of 93%). The LDA of the Hab-horizon had a misclassification of 24%, which was probably related to the smaller test set and the higher depth of this horizon. The MLR predicted the depth of the Apb-, Ahb- and Hab-horizons with relative root mean square errors (RMSEs) of 7, 3 and 13%, respectively, in the pseudo-3D area. MLR had a lower accuracy for the 2D transect compared to the pseudo-3D area. Overall, the use of LDA and MLR has been an efficient methodological approach for predicting buried horizon positions. Highlights The suitability of geoelectrical measurements for digital modelling of diagnostic buried soil horizons was determined. LDA and MLR were used to detect multiple horizons with geoelectrical devices and terrain attributes. Geoelectrical variables were significant predictors of the position of the target soil horizons. The use of these tested digital technologies gives an opportunity to develop high-resolution soil mapping procedures. KW - colluvium depth modelling KW - electrical conductivity KW - electrical resistivity tomography KW - electromagnetic induction KW - EM38DD KW - linear discriminant analysis KW - linear regression KW - moraine soil landscape Y1 - 2019 SN - 1351-0754 SN - 1365-2389 VL - 71 IS - 1 SP - 10 EP - 26 PB - Wiley CY - Hoboken ER - TY - JOUR A1 - McNamara, James T1 - Rezension zu: Shannon-Henderson, Kelly E.: Religion and Memory in Tacitus’ Annals. Oxford: Oxford University Press, 2019. - ISBN 978-0-1988-3276-8 JF - Arys : antigüedad: religiones y sociedades Y1 - 2020 U6 - https://doi.org/https://doi.org/10.20318/arys.2020.5692 SN - 1575-166X SN - 2173-6847 VL - 18 SP - 493 PB - Univ., Servicio de Publ. CY - Huelva ER - TY - JOUR A1 - Carlà-Uhink, Filippo T1 - Review of Helen Roche & Kyriakos Demetriou: Brill’s Companion to the Classics, Fascist Italy and Nazi Germany JF - thersites 10: Modern Identities and Classical Antiquity Y1 - 2020 U6 - https://doi.org/10.34679/thersites.vol10.144 VL - 2019 IS - 10 SP - 234 EP - 238 ER -