TY - JOUR A1 - Gaeckle, Maren A1 - Domahs, Frank A1 - Kartmann, Angelika A1 - Tomandl, Bernd A1 - Frank, Ulrike T1 - Predictors of Penetration-Aspiration in Parkinson’s Disease Patients With Dysphagia BT - a retrospective analysis JF - Annals of Otology, Rhinology and Laryngology N2 - Methods: The data of 89 PD patients with dysphagia who underwent routinely conducted videofluoroscopic studies of swallowing (VFSS) were included in this retrospective study. The occurrence of penetration-aspiration was defined as scores >= 3 on the Penetration-Aspiration Scale (PAS). Four commonly reported signs of dysphagia in PD patients were evaluated as possible predictors. Furthermore, the relationships between the occurrence of penetration-aspiration and liquid bolus volume as well as clinical severity of PD (modified Hoehn and Yahr scale) were examined. Results: Logistic regression showed that a delayed initiation of the pharyngeal swallow (odds ratio [OR] = 7.47, P = .008) and a reduced hyolaryngeal excursion (OR = 5.13, P = .012) were predictors of penetration-aspiration. Moreover, there was a strong, positive correlation between increasing liquid bolus volume and penetration-aspiration (gamma = 0.71, P < .001). No correlation was found between severity of PD and penetration-aspiration (gamma = 0.077, P = .783). Conclusion: Results of the present study allow for a better understanding of penetration-aspiration risk in PD patients. They are useful for treatment planning in order to improve safe oral intake and adequate nutrition. KW - pneumonia KW - videofluoroscopy Y1 - 2019 U6 - https://doi.org/10.1177/0003489419841398 SN - 0003-4894 SN - 1943-572X VL - 128 IS - 8 SP - 728 EP - 735 PB - Sage Publ. CY - Thousand Oaks ER -