TY  - JOUR
A1  - Wertheimer, Michael R.
A1  - St-Georges-Robillard, Amelie
A1  - Lerouge, Sophie
A1  - Mwale, Fackson
A1  - Elkin, Bentsian
A1  - Oehr, Christian
A1  - Wirges, Werner
A1  - Gerhard, Reimund
T1  - Amine-rich organic thin films for cell culture - possible electrostatic effects in cell-surface interactions
JF  - Japanese journal of applied physics
N2  - In recent communications from these laboratories, we observed that amine-rich thin organic layers are very efficient surfaces for the adhesion of mammalian cells. We prepare such deposits by plasma polymerization at low pressure, atmospheric pressure, or by vacuum-ultraviolet photo-polymerization. More recently, we have also investigated a commercially available material, Parylene diX AM. In this article we first briefly introduce literature relating to electrostatic interactions between cells, proteins, and charged surfaces. We then present certain selected cell-response results that pertain to applications in orthopedic and cardiovascular medicine: we discuss the influence of surface properties on the observed behaviors of two particular cell lines, human U937 monocytes, and Chinese hamster ovary cells. Particular emphasis is placed on possible electrostatic attractive forces due to positively charged R-NH3+ groups and negatively charged proteins and cells, respectively. Experiments carried out with electrets, polymers with high positive or negative surface potentials are added for comparison.
Y1  - 2012
U6  - https://doi.org/10.1143/JJAP.51.11PJ04
SN  - 0021-4922
VL  - 51
IS  - 11
PB  - Japan Soc. of Applied Physics
CY  - Tokyo
ER  -