TY - JOUR A1 - Boedeker, Hendrik Ulrich A1 - Beta, Carsten A1 - Frank, Till D. A1 - Bodenschatz, Eberhard T1 - Quantitative analysis of random ameboid motion N2 - We quantify random migration of the social ameba Dictyostelium discoideum. We demonstrate that the statistics of cell motion can be described by an underlying Langevin-type stochastic differential equation. An analytic expression for the velocity distribution function is derived. The separation into deterministic and stochastic parts of the movement shows that the cells undergo a damped motion with multiplicative noise. Both contributions to the dynamics display a distinct response to external physiological stimuli. The deterministic component depends on the developmental state and ambient levels of signaling substances, while the stochastic part does not. Y1 - 2010 UR - http://iopscience.iop.org/0295-5075/ U6 - https://doi.org/10.1209/0295-5075/90/28005 SN - 0295-5075 ER -