TY  - GEN
A1  - Peter, Martin G.
A1  - Muiva, Lois M.
A1  - Yenesew, Abiy
A1  - Derese, Solomon
A1  - Heydenreich, Matthias
A1  - Akala, Hoseah M.
A1  - Eyase, Fredrick
A1  - Waters, Norman C.
A1  - Mutai, Charles
A1  - Keriko, Joseph M.
A1  - Walsh, Douglas S.
T1  - Antiplasmodial β-hydroxydihydrochalcone from seedpods of Tephrosia elata
N2  - From the seedpods of Tephrosia elata, a new β-hydroxydihydrochalcone named (S)-elatadihydrochalcone was isolated. In addition, the known flavonoids obovatachalcone, obovatin, obovatin methyl ether and deguelin were identified. The structures were determined on the basis of spectroscopic evidence. The crude extract and the flavonoids obtained from the seedpods of this plant showed antiplasmodial activities. The literature NMR data on β-hydroxydihydrochalcones is reviewed and the identity of some of the compounds assigned β-hydroxydihydrochalcone skeleton is questioned.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 118 
KW  - Tephrosia elata
KW  - Leguminosae
KW  - Seedpods
KW  - (S)-Elatadihydrochalcone
KW  - β-Hydroxydihydrochalcone
Y1  - 2009
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44437
ER  - 
TY  - GEN
A1  - Peter, Martin G.
A1  - Yenesew, Abiy
A1  - Twinomuhwezi, Hannington
A1  - Kabaru, Jacques M.
A1  - Akala, Hoseah M.
A1  - Kiremire, Bernard T.
A1  - Heydenreich, Matthias
A1  - Eyase, Fredrick
A1  - Waters, Norman C.
A1  - Walsh, Douglas S.
T1  - Antiplasmodial and larvicidal flavonoids from Derris trifoliata
N2  - From the dichloromethane-methanol (1:1) extract of the seed pods of Derris trifoliata, a new flavanone derivative (S)-lupinifolin 4´-methyl ether was isolated. In addition, the known flavonoids lupinifolin and rotenone were identified. The structures were determined on the basis of spectroscopic evidence. Lupinfolin showed moderate in vitro antiplasmodial activity against the D6 (chloroquine-sensitive) and W2 (chloroquineresistant) strains of Plasmodium falciparum. The different parts of this plant showed larvicidal activities against Aedes aegypti and rotenoids were identified as the active principles.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - paper 121 
KW  - Derris trifoliata
KW  - Leguminosae
KW  - Flavanone
KW  - (S)-Lupinifolin 4´-methyl ether
KW  - Lupinifolin
Y1  - 2009
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-44614
ER  -