TY  - JOUR
A1  - Tschorn, Mira
A1  - Rieckmann, Nina
A1  - Arolt, Volker
A1  - Beer, Katja
A1  - Haverkamp, Wilhelm
A1  - Martus, Peter
A1  - Waltenberger, Johannes
A1  - Müller-Nordhorn, Jacqueline
A1  - Ströhle, Andreas
T1  - Erkennungsgüte dreier deutschsprachiger Screeninginstrumente für Depression bei hospitalisierten Patienten mit koronarer Herzerkrankung
T1  - Diagnostic Accuracy of German Depression Screenings in Patients with Coronary Heart Disease
JF  - Psychiatrische Praxis
N2  - Ziel Vergleich der Erkennungsgüte von drei Depressions-Screeninginstrumenten bei Patienten mit koronarer Herzerkrankung (KHK).
Methodik 1019 KHK-Patienten erhielten den Patient Health Questionnaire (PHQ-9 und PHQ-2) und die Hospital Anxiety and Depression Scale (HADS-D) sowie ein klinisches Interview (Composite International Diagnostic Interview) als Referenzstandard.
Ergebnisse Bezüglich der Erkennungsgüte waren PHQ-9 und HADS-D dem PHQ-2 überlegen. Optimale Cut-off-Werte waren 7 (PHQ-9 und HADS-D) und 2 (PHQ-2).
Schlussfolgerung PHQ-9 und HADS-D haben eine vergleichbare Diskriminationsfähigkeit für depressive Störungen bei KHK-Patienten.
N2  - Objective To compare the diagnostic accuracy of German depression screening instruments in patients with coronary heart disease (CHD). Methods 1019 CHD patients completed the Patient Health Questionnaire (PHQ-9 and PHQ-2) and the Hospital Anxiety and Depression Scale (HADS-D). The Composite International Diagnostic Interview served as reference standard for "any depressive disorder" and "major depression". Results The accuracy of the PHQ-9 and the HADS-D was comparable according to the area under the curve, and both were superior to the PHQ-2. The optimal cut-off according to the Youden index (maximum sum of sensitivity and specificity) was 7 for both instruments. At this optimal cut-off, the PHQ-9 had a higher sensitivity compared to the HADS-D, but a lower specificity (below 68). Results remained similar when patients who reported that they currently underwent treatment for depression were excluded. Conclusion The PHQ-9 and the HADS-D have comparable overall diagnostic accuracy in CHD patients. In line with previous screening studies with CHD patients, the optimal cut-offs were below the cut-offs that are recommended in the literature.
KW  - coronary artery disease
KW  - depression
KW  - diagnosis
KW  - screening
KW  - validity
Y1  - 2019
U6  - https://doi.org/10.1055/s-0042-123434
SN  - 0303-4259
SN  - 1439-0876
VL  - 46
IS  - 1
SP  - 41
EP  - 48
PB  - Thieme
CY  - Stuttgart
ER  -