TY  - GEN
A1  - Stuetz, Wolfgang
A1  - Weber, Daniela
A1  - Dollé, Martijn E. T.
A1  - Jansen, Eugène
A1  - Grubeck-Loebenstein, Beatrix
A1  - Fiegl, Simone
A1  - Toussaint, Olivier
A1  - Bernhardt, Juergen
A1  - Gonos, Efstathios S.
A1  - Franceschi, Claudio
A1  - Sikora, Ewa
A1  - Moreno-Villanueva, María
A1  - Breusing, Nicolle
A1  - Grune, Tilman
A1  - Bürkle, Alexander
T1  - Plasma carotenoids, tocopherols, and retinol in the age-stratified (35–74 years) general population
BT  - a cross-sectional study in six European countries
T2  - Nutrients
N2  - Blood micronutrient status may change with age. We analyzed plasma carotenoids, α-/γ-tocopherol, and retinol and their associations with age, demographic characteristics, and dietary habits (assessed by a short food frequency questionnaire) in a cross-sectional study of 2118 women and men (age-stratified from 35 to 74 years) of the general population from six European countries. Higher age was associated with lower lycopene and α-/β-carotene and higher β-cryptoxanthin, lutein, zeaxanthin, α-/γ-tocopherol, and retinol levels. Significant correlations with age were observed for lycopene (r = −0.248), α-tocopherol (r = 0.208), α-carotene (r = −0.112), and β-cryptoxanthin (r = 0.125; all p < 0.001). Age was inversely associated with lycopene (−6.5% per five-year age increase) and this association remained in the multiple regression model with the significant predictors (covariables) being country, season, cholesterol, gender, smoking status, body mass index (BMI (kg/m2)), and dietary habits. The positive association of α-tocopherol with age remained when all covariates including cholesterol and use of vitamin supplements were included (1.7% vs. 2.4% per five-year age increase). The association of higher β-cryptoxanthin with higher age was no longer statistically significant after adjustment for fruit consumption, whereas the inverse association of α-carotene with age remained in the fully adjusted multivariable model (−4.8% vs. −3.8% per five-year age increase). We conclude from our study that age is an independent predictor of plasma lycopene, α-tocopherol, and α-carotene.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 449 
KW  - carotenoids
KW  - plasma
KW  - age
KW  - Europe
KW  - micronutrient
KW  - lycopene
KW  - retinol
KW  - tocopherols
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-407659
ER  -