TY  - JOUR
A1  - Unterhuber, Angelika
A1  - Povazay, B.
A1  - Bizheva, K.
A1  - Hermann, B.
A1  - Sattmann, Harald
A1  - Stingl, A.
A1  - Le, Trang
A1  - Seefeldt, Michael
A1  - Menzel, Ralf
A1  - Preusser, Matthias
A1  - Budka, Herbert
A1  - Schubert, Christian
A1  - Reitsamer, H.
A1  - Ahnelt, Peter Kurt
A1  - Morgan, J. E.
T1  - Advances in broad bandwidth light sources for ultrahigh resolution optical coherence tomography
N2  - Novel ultra-broad bandwidth light sources enabling unprecedented sub-2 pm axial resolution over the 400 nm-1700 nm wavelength range have been developed and evaluated with respect to their feasibility for clinical ultrahigh resolution optical coherence tomography (UHR OCT) applications. The state-of-the-art light sources described here include a compact Kerr lens mode locked Ti:sapphire laser (lambda(c) = 785 nm, Deltalambda = 260 nm, P-out = 50 mW) and different nonlinear fibre-based light sources with spectral bandwidths (at full width at half maximum) up to 350 nm at lambda(c) = 1130 nm and 470 nm at lambda(c) = 1375 run. In vitro UHR OCT imaging is demonstrated at multiple wavelengths in human cancer cells, animal ganglion cells as well as in neuropathologic and ophthalmic biopsies in order to compare and optimize UHR OCT image contrast, resolution and penetration depth
Y1  - 2004
SN  - 0031-9155
ER  - 
TY  - JOUR
A1  - Seefeldt, Michael
A1  - Heuer, Axel
A1  - Menzel, Ralf
T1  - Compact white-light source with an average output power of 2.4 W and 900 nm spectral bandwidth
Y1  - 2003
ER  - 
TY  - JOUR
A1  - Jechow, Andreas
A1  - Seefeldt, Michael
A1  - Kurzke, Henning
A1  - Heuer, Axel
A1  - Menzel, Ralf
T1  - Enhanced two-photon excited fluorescence from imaging agents using true thermal light
JF  - Nature photonics
N2  - Two-photon excited fluorescence (TPEF) is a standard technique in modern microscopy(1), but is still affected by photodamage to the probe. It has been proposed that TPEF can be enhanced using entangled photons(2,3), but this has proven challenging. Recently, it was shown that some features of entangled photons can be mimicked with thermal light, which finds application in ghost imaging(4), subwavelength lithography(5) and metrology(6). Here, we use true thermal light from a superluminescent diode to demonstrate TPEF that is enhanced compared to coherent light, using two common fluorophores and luminescent quantum dots, which suit applications in imaging and microscopy. We find that the TPEF rate is directly proportional to the measured(7) degree of second-order coherence, as predicted by theory. Our results show that photon bunching in thermal light can be exploited in two-photon microscopy, with the photon statistic providing a new degree of freedom.
Y1  - 2013
U6  - https://doi.org/10.1038/NPHOTON.2013.271
SN  - 1749-4885
SN  - 1749-4893
VL  - 7
IS  - 12
SP  - 973
EP  - 976
PB  - Nature Publ. Group
CY  - London
ER  -