TY  - JOUR
A1  - Shainyan, Bagrat A.
A1  - Kirpichenko, Svetlana V.
A1  - Kleinpeter, Erich
T1  - Synthesis and conformational analysis of 1,3-azasilinanes
JF  - Tetrahedron
N2  - 1-Isopropyl-3-methyl-3-phenyl-1,3-azasilinane 1 and 1-isopropyl-3,3-dimethyl-1,3-azasilinane 2 were synthesized and a detailed analysis of their NMR spectra, conformational equilibria and ring inversion processes is presented. Low temperature H-1/C-13 NMR spectroscopy, iteration of the H-1 NMR spectra and quantum chemical calculations showed slight predominance of the PheqMeax over the PhaxMeeq conformer of 1 at low temperature. The barrier for the chair to chair interconversion of both compounds was measured to be 8.25 kcal/mol.
KW  - 1,3-Azasilinanes
KW  - Conformational analysis
KW  - Dynamic NMR spectroscopy
KW  - Quantum chemical calculations
KW  - Ring current effect
Y1  - 2012
U6  - https://doi.org/10.1016/j.tet.2012.05.106
SN  - 0040-4020
VL  - 68
IS  - 36
SP  - 7494
EP  - 7501
PB  - Elsevier
CY  - Oxford
ER  -