TY - JOUR A1 - Kühne, Franziska A1 - Meinders, C. A1 - Mohr, H. A1 - Hafenbrack, K. A1 - Kieseritzky, K. A1 - Rosenberger, C. A1 - Haerter, M. A1 - Schulz-Kindermann, F. A1 - Klinger, R. A1 - Nestoriuc, A. Y. T1 - Psychological treatments for pain in cancer patients. A systematic review on the current state of research JF - Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie N2 - In cancer patients, pain is one of the main symptoms and especially in the late stages of disease, these symptoms can be associated with considerable suffering. In psycho-oncology, preliminary psychological therapies targeting cancer pain have been tested; however, a systematic review of available interventions is lacking, especially considering their dissemination, evidence base, study quality, and the comparison with established treatments. Therefore, the aim of the current study is to systematically review the current research on psychological treatments for pain in cancer patients. During May 2014, MEDLINE, PsycINFO, PSYNDEX, and CENTRAL databases were searched. Psychological treatments for pain in adult cancer patients studied in randomized, controlled trials (RCTs) and referring to pain as primary or secondary outcome were included. After examination for inclusion, structured data extraction and assessment followed. Data were synthesized narratively. In the review, 32 RCTs were included. Studies mainly referred to patients with breast cancer or patients in earlier stages of the disease. The methodological quality of included studies was heterogeneous. Most commonly, short interventions were delivered by nurses in out-patient settings. Interventions including education and relaxation techniques were utilized most often, followed by interventions with behavioral or cognitive components. A need for research persists regarding efficacy of current psychotherapeutic interventions, or the role of mediator variables (e. g., coping) on pain perception in cancer patients. Studies with high methodological quality which comprehensively and transparently report on interventions and designs are lacking. KW - Neoplasms, psychology KW - Education, patients KW - Relaxation KW - Behavior therapy KW - Cognitive therapy Y1 - 2016 U6 - https://doi.org/10.1007/s00482-016-0169-7 SN - 0932-433X SN - 1432-2129 VL - 30 SP - 496 EP - 509 PB - Springer CY - New York ER - TY - JOUR A1 - Nickerson, David A1 - Atalag, Koray A1 - de Bono, Bernard A1 - Geiger, Joerg A1 - Goble, Carole A1 - Hollmann, Susanne A1 - Lonien, Joachim A1 - Mueller, Wolfgang A1 - Regierer, Babette A1 - Stanford, Natalie J. A1 - Golebiewski, Martin A1 - Hunter, Peter T1 - The Human Physiome: how standards, software and innovative service infrastructures are providing the building blocks to make it achievable JF - Interface focus N2 - Reconstructing and understanding the Human Physiome virtually is a complex mathematical problem, and a highly demanding computational challenge. Mathematical models spanning from the molecular level through to whole populations of individuals must be integrated, then personalized. This requires interoperability with multiple disparate and geographically separated data sources, and myriad computational software tools. Extracting and producing knowledge from such sources, even when the databases and software are readily available, is a challenging task. Despite the difficulties, researchers must frequently perform these tasks so that available knowledge can be continually integrated into the common framework required to realize the Human Physiome. Software and infrastructures that support the communities that generate these, together with their underlying standards to format, describe and interlink the corresponding data and computer models, are pivotal to the Human Physiome being realized. They provide the foundations for integrating, exchanging and re-using data and models efficiently, and correctly, while also supporting the dissemination of growing knowledge in these forms. In this paper, we explore the standards, software tooling, repositories and infrastructures that support this work, and detail what makes them vital to realizing the Human Physiome. KW - Human Physiome KW - standards KW - repositories KW - service infrastructure KW - reproducible science KW - managing big data Y1 - 2016 U6 - https://doi.org/10.1098/rsfs.2015.0103 SN - 2042-8898 SN - 2042-8901 VL - 6 SP - 57 EP - 61 PB - Royal Society CY - London ER - TY - JOUR A1 - Mürbe, Ulrike T1 - Normativer Individualismus in Ethik, Politik und Recht [rezensiert von Ulrike Mürbe] JF - MenschenRechtsMagazin : MRM ; Informationen, Meinungen, Analysen N2 - Buchbesprechung: Dietmar von der Pfordten, Lorenz Kähler (Hrsg.), Normativer Individualismus in Ethik, Politik und Recht, Tübingen: Mohr Siebeck, 2014, 255 Seiten, ISBN 978-3-16-153629-8, 54,00 €. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95163 SN - 1434-2820 VL - 21 IS - 1 SP - 88 EP - 91 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Talabardon, Susanne T1 - Karl Erich Grözinger: Jüdisches Denken. Theologie – Philosophie – Mystik / rezensiert von Susanne Talabardon JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Karl Erich Grözinger: Jüdisches Denken. Theologie – Philosophie – Mystik, Bd. 4: Zionismus und Schoah, Frankfurt am Main: Campus Verlag 2015. 660 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99860 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 241 EP - 245 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Rasumny, Wiebke T1 - Clemens P. Sidorko: Basel und der jiddische Buchdruck (1557–1612). Kulturexport in der Frühen Neuzeit / rezensiert von Wiebke Rasumny JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Rezensiertes Werk: Clemens P. Sidorko: Basel und der jiddische Buchdruck (1557–1612). Kulturexport in der Frühen Neuzeit, Schriften der Universitätsbibliothek Basel, Bd. 8, Basel: Schwabe Verlag 2014. 487 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99878 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 245 EP - 248 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Arnold, Rafael D. T1 - Margarethe Boockmann: Schrift als Stigma. Hebräische und hebraisierende Inschriften auf Gemälden der Spätgotik / rezensiert von: Rafael D. Arnold JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Rezensiertes Werk: Margarethe Boockmann: Schrift als Stigma. Hebräische und hebraisierende Inschriften auf Gemälden der Spätgotik, Schriften der Hochschule für Jüdische Studien Heidelberg, Bd. 16, Heidelberg: Universitätsverlag Winter 2013. 698 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99828 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 225 EP - 229 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - D'Aprile, Iwan-Michelangelo T1 - Costuming Genders: Acting as an Invention of the Enlightenment JF - German history : the journal of the German History Societ Y1 - 2016 U6 - https://doi.org/10.1093/gerhis/ghv109 SN - 0266-3554 SN - 1477-089X VL - 34 SP - 138 EP - 139 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Schulz, Michael Karl T1 - Agnieszka Jagodzińska / Marcin Wodziński (Hrsg.): Izraelita 1866–1915. Wybór źródeł [Izraelita 1866–1915. Quellenauswahl] / rezensiert von Michał Szulc JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Rezensiertes Werk: Agnieszka Jagodzińska / Marcin Wodziński (Hrsg.): Izraelita 1866–1915. Wybór źródeł [Izraelita 1866–1915. Quellenauswahl], מקור / Źródła, Bd. 3, Kraków / Budapeszt: Austeria 2015. 540 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99810 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 221 EP - 225 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Salzer, Dorothea M. T1 - Naphtali Herz Wessely: Worte des Friedens und der Wahrheit. Dokumente einer Kontroverse über Erziehung in der europäischen Spätaufklärung. Herausgegeben, eingeleitet und kommentiert von Ingrid Lohmann, mitherausgegeben von Rainer Wenzel / Uta Lohmann. Aus dem Hebräischen übersetzt und mit Anmerkungen versehen von Rainer Wenzel / rezensiert von Dorothea Salzer JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Rezensiertes Werk: Naphtali Herz Wessely: Worte des Friedens und der Wahrheit. Dokumente einer Kontroverse über Erziehung in der europäischen Spätaufklärung. Herausgegeben, eingeleitet und kommentiert von Ingrid Lohmann, mitherausgegeben von Rainer Wenzel / Uta Lohmann. Aus dem Hebräischen übersetzt und mit Anmerkungen versehen von Rainer Wenzel, Jüdische Bildungsgeschichte in Deutschland, Bd. 8, Münster: Waxmann 2014. 800 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99807 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 218 EP - 221 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Sperfeld, Erik A1 - Raubenheimer, David A1 - Wacker, Alexander T1 - Bridging factorial and gradient concepts of resource co-limitation: towards a general framework applied to consumers JF - Ecology letters N2 - Organism growth can be limited either by a single resource or by multiple resources simultaneously (co-limitation). Efforts to characterise co-limitation have generated two influential approaches. One approach uses limitation scenarios of factorial growth assays to distinguish specific types of co-limitation; the other uses growth responses spanned over a continuous, multi-dimensional resource space to characterise different types of response surfaces. Both approaches have been useful in investigating particular aspects of co-limitation, but a synthesis is needed to stimulate development of this recent research area. We address this gap by integrating the two approaches, thereby presenting a more general framework of co-limitation. We found that various factorial (co-)limitation scenarios can emerge in different response surface types based on continuous availabilities of essential or substitutable resources. We tested our conceptual co-limitation framework on data sets of published and unpublished studies examining the limitation of two herbivorous consumers in a two-dimensional resource space. The experimental data corroborate the predictions, suggesting a general applicability of our co-limitation framework to generalist consumers and potentially also to other organisms. The presented framework might give insight into mechanisms that underlie co-limitation responses and thus can be a seminal starting point for evaluating co-limitation patterns in experiments and nature. KW - Consumer KW - essential nutrient KW - factorial design KW - food quality KW - growth rate KW - multi-nutrient limitation KW - nutritional ecology KW - performance landscape KW - substitutable resource KW - synergistic effect Y1 - 2016 U6 - https://doi.org/10.1111/ele.12554 SN - 1461-023X SN - 1461-0248 VL - 19 SP - 201 EP - 215 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - de Vinuesa, Amaya Garcia A1 - Abdelilah-Seyfried, Salim A1 - Knaus, Petra A1 - Zwijsen, An A1 - Bailly, Sabine T1 - BMP signaling in vascular biology and dysfunction JF - New journal of physics : the open-access journal for physics N2 - The vascular system is critical for developmental growth, tissue homeostasis and repair but also for tumor development. Bone morphogenetic protein (BMP) signaling has recently emerged as a fundamental pathway of the endothelium by regulating cardiovascular and lymphatic development and by being causative for several vascular dysfunctions. Two vascular disorders have been directly linked to impaired BMP signaling: pulmonary arterial hypertension and hereditary hemorrhagic telangiectasia. Endothelial BMP signaling critically depends on the cellular context, which includes among others vascular heterogeneity, exposure to flow, and the intertwining with other signaling cascades (Notch, WNT, Hippo and hypoxia). The purpose of this review is to highlight the most recent findings illustrating the clear need for reconsidering the role of BMPs in vascular biology. (C) 2015 Elsevier Ltd. All rights reserved. KW - Bone morphogenetic proteins (BMP) KW - Signaling KW - Vasculature KW - Development KW - Disease Y1 - 2016 U6 - https://doi.org/10.1016/j.cytogfr.2015.12.005 SN - 1359-6101 SN - 1879-0305 VL - 27 SP - 65 EP - 79 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Haack, Timm A1 - Abdelilah-Seyfried, Salim T1 - The force within: endocardial development, mechanotransduction and signalling during cardiac morphogenesis JF - Development : Company of Biologists N2 - Endocardial cells are cardiac endothelial cells that line the interior of the heart tube. Historically, their contribution to cardiac development has mainly been considered from a morphological perspective. However, recent studies have begun to define novel instructive roles of the endocardium, as a sensor and signal transducer of biophysical forces induced by blood flow, and as an angiocrine signalling centre that is involved in myocardial cellular morphogenesis, regeneration and reprogramming. In this Review, we discuss how the endocardium develops, how endocardial-myocardial interactions influence the developing embryonic heart, and how the dysregulation of blood flowresponsive endocardial signalling can result in pathophysiological changes. KW - Endocardium KW - Cardiac development KW - Hemodynamics KW - Bmp KW - Kruppel-like factor 2 KW - Vegf KW - Mechanotransduction KW - Zebrafish KW - Mouse Y1 - 2016 U6 - https://doi.org/10.1242/dev.131425 SN - 0950-1991 SN - 1477-9129 VL - 143 SP - 373 EP - 386 PB - Company of Biologists Limited CY - Cambridge ER - TY - JOUR A1 - Yan, Wenhao A1 - Chen, Dijun A1 - Kaufmann, Kerstin T1 - Molecular mechanisms of floral organ specification by MADS domain proteins JF - Current opinion in plant biology N2 - Flower development is a model system to understand organ specification in plants. The identities of different types of floral organs are specified by homeotic MADS transcription factors that interact in a combinatorial fashion. Systematic identification of DNA-binding sites and target genes of these key regulators show that they have shared and unique sets of target genes. DNA binding by MADS proteins is not based on ‘simple’ recognition of a specific DNA sequence, but depends on DNA structure and combinatorial interactions. Homeotic MADS proteins regulate gene expression via alternative mechanisms, one of which may be to modulate chromatin structure and accessibility in their target gene promoters. Y1 - 2016 U6 - https://doi.org/10.1016/j.pbi.2015.12.004 SN - 1369-5266 SN - 1879-0356 VL - 29 SP - 154 EP - 162 PB - Elsevier CY - London ER - TY - JOUR A1 - Gangloff, Niklas A1 - Ulbricht, Juliane A1 - Lorson, Thomas A1 - Schlaad, Helmut A1 - Luxenhofer, Robert T1 - Peptoids and Polypeptoids at the Frontier of Supra- and Macromolecular Engineering JF - Chemical reviews Y1 - 2016 U6 - https://doi.org/10.1021/acs.chemrev.5b00201 SN - 0009-2665 SN - 1520-6890 VL - 116 SP - 1753 EP - 1802 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Terao, Mineko A1 - Romao, Maria Joao A1 - Leimkühler, Silke A1 - Bolis, Marco A1 - Fratelli, Maddalena A1 - Coelho, Catarina A1 - Santos-Silva, Teresa A1 - Garattini, Enrico T1 - Structure and function of mammalian aldehyde oxidases JF - Archives of toxicology : official journal of EUROTOX N2 - Mammalian aldehyde oxidases (AOXs; EC1.2.3.1) are a group of conserved proteins belonging to the family of molybdo-flavoenzymes along with the structurally related xanthine dehydrogenase enzyme. AOXs are characterized by broad substrate specificity, oxidizing not only aromatic and aliphatic aldehydes into the corresponding carboxylic acids, but also hydroxylating a series of heteroaromatic rings. The number of AOX isoenzymes expressed in different vertebrate species is variable. The two extremes are represented by humans, which express a single enzyme (AOX1) in many organs and mice or rats which are characterized by tissue-specific expression of four isoforms (AOX1, AOX2, AOX3, and AOX4). In vertebrates each AOX isoenzyme is the product of a distinct gene consisting of 35 highly conserved exons. The extant species-specific complement of AOX isoenzymes is the result of a complex evolutionary process consisting of a first phase characterized by a series of asynchronous gene duplications and a second phase where the pseudogenization and gene deletion events prevail. In the last few years remarkable advances in the elucidation of the structural characteristics and the catalytic mechanisms of mammalian AOXs have been made thanks to the successful crystallization of human AOX1 and mouse AOX3. Much less is known about the physiological function and physiological substrates of human AOX1 and other mammalian AOX isoenzymes, although the importance of these proteins in xenobiotic metabolism is fairly well established and their relevance in drug development is increasing. This review article provides an overview and a discussion of the current knowledge on mammalian AOX. KW - Aldehyde oxidase KW - Molybdo-flavoenzymes KW - Xanthine oxidoreductase KW - Drug metabolism Y1 - 2016 U6 - https://doi.org/10.1007/s00204-016-1683-1 SN - 0340-5761 SN - 1432-0738 VL - 90 SP - 753 EP - 780 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Schmidt, Katja A1 - Sachse, Rene A1 - Walz, Ariane T1 - Current role of social benefits in ecosystem service assessments JF - Landscape and urban planning : an international journal of landscape ecology, planning and design N2 - Ecosystem services have a significant impact on human wellbeing. While ecosystem services are frequently represented by monetary values, social values and underlying social benefits remain underexplored. The purpose of this study is to assess whether and how social benefits have been explicitly addressed within socio-economic and socio-cultural ecosystem services research, ultimately allowing a better understanding between ecosystem services and human well-being. In this paper, we reviewed 115 international primary valuation studies and tested four hypotheses associated to the identification of social benefits of ecosystem services using logistic regressions. Tested hypotheses were that (1) social benefits are mostly derived in studies that assess cultural ecosystem services as opposed to other ecosystem service types, (2) there is a pattern of social benefits and certain cultural ecosystem services assessed simultaneously, (3) monetary valuation techniques go beyond expressing monetary values and convey social benefits, and (4) directly addressing stakeholdeŕs views the consideration of social benefits in ecosystem service assessments. Our analysis revealed that (1) a variety of social benefits are valued in studies that assess either of the four ecosystem service types, (2) certain social benefits are likely to co-occur in combination with certain cultural ecosystem services, (3) of the studies that employed monetary valuation techniques, simulated market approaches overlapped most frequently with the assessment of social benefits and (4) studies that directly incorporate stakeholder's views were more likely to also assess social benefits. KW - Literature review KW - Non-monetary valuation KW - Monetary valuation KW - Social valuation Y1 - 2016 U6 - https://doi.org/10.1016/j.landurbplan.2016.01.005 SN - 0169-2046 SN - 1872-6062 VL - 149 SP - 49 EP - 64 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Erdossy, Julia A1 - Horvath, Viola A1 - Yarman, Aysu A1 - Scheller, Frieder W. A1 - Gyurcsanyi, Robert E. T1 - Electrosynthesized molecularly imprinted polymers for protein recognition JF - Trends in Analytical Chemistry N2 - Molecularly imprinted polymers (MIPs) for the recognition of proteins are expected to possess high affinity through the establishment of multiple interactions between the polymer matrix and the large number of functional groups of the target. However, while highly affine recognition sites need building blocks rich in complementary functionalities to their target, such units are likely to generate high levels of nonspecific binding. This paradox, that nature solved by evolution for biological receptors, needs to be addressed by the implementation of new concepts in molecular imprinting of proteins. Additionally, the structural variability, large size and incompatibility with a range of monomers made the development of protein MIPs to take a slow start. While the majority of MIP preparation methods are variants of chemical polymerization, the polymerization of electroactive functional monomers emerged as a particularly advantageous approach for chemical sensing application. Electropolymerization can be performed from aqueous solutions to preserve the natural conformation of the protein templates, with high spatial resolution and electrochemical control of the polymerization process. This review compiles the latest results, identifying major trends and providing an outlook on the perspectives of electrosynthesised protein-imprinted MIPs for chemical sensing. (C) 2016 Elsevier B.V. All rights reserved. KW - Molecularly imprinted polymers KW - Proteins KW - Surface imprinting KW - Electropolymerization KW - Nanostructuring KW - Hybrid nanofilms Y1 - 2016 U6 - https://doi.org/10.1016/j.trac.2015.12.018 SN - 0165-9936 SN - 1879-3142 VL - 79 SP - 179 EP - 190 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Doetterl, Sebastian A1 - Berhe, Asmeret Asefaw A1 - Nadeu, Elisabet A1 - Wang, Zhengang A1 - Sommer, Michael A1 - Fiener, Peter T1 - Erosion, deposition and soil carbon: A review of process-level controls, experimental tools and models to address C cycling in dynamic landscapes JF - Earth science reviews : the international geological journal bridging the gap between research articles and textbooks N2 - The role of soil erosion in terrestrial carbon (C) sequestration and release remains one of the most important uncertainties in our attempts to determine the potential of soils to mediate climate change. Despite its widely recognized importance for terrestrial C sequestration, to date, no Earth System Model (ESM) implements soil erosion effects on carbon cycling in sufficient detail. So far, available studies have mostly investigated the magnitude of erosional C transport and in-situ measurements of vertical C fluxes on the catchment or regional scale. Recognizing the need to adequately represent C erosion processes and controls in ESMs, we provide a comprehensive cross-disciplinary review on lateral C redistribution in the landscape and discuss the implications for bio-geochemical cycling of carbon. We present current knowledge on the role of erosional C distribution in controlling the stabilization and release of C in soils, taking into consideration the important geomorphic, ecological, hydrologic, pedologic and micro-climatic processes and controls that affect soil organic carbon (SOC) stock, fluxes, and persistence in dynamic landscapes. Further, we provide an overview on latest experimental and modelling approaches that are being used to investigate the role of erosion in the carbon cycle. Finally, to advance our understanding of the role of soil redistribution in biogeochemical cycles of essential elements, we discuss the most promising topics for future research in this field. (C) 2015 Elsevier B.V. All rights reserved. KW - Soil erosion KW - Soil deposition KW - Carbon redistribution KW - Terrestrial C sink Y1 - 2016 U6 - https://doi.org/10.1016/j.earscirev.2015.12.005 SN - 0012-8252 SN - 1872-6828 VL - 154 SP - 102 EP - 122 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bacskai-Atkari, Julia T1 - Descriptive typology and linguistic theory: A study in the morphosyntax of relative clauses JF - Acta linguistica Hungarica : an international journal of linguistics Y1 - 2016 SN - 1216-8076 SN - 1588-2624 VL - 63 SP - 97 EP - 112 PB - Akadémiai Kiadó CY - Budapest ER - TY - JOUR A1 - Haßler, Gerda T1 - French in the Baroque and Enlightenment. Studies on the Linguistic Thinking in Germany in the 17th and 18th Centuries JF - Zeitschrift für Romanische Philologie Y1 - 2016 U6 - https://doi.org/10.1515/zrp-2016-0014 SN - 0049-8661 SN - 1865-9063 VL - 132 SP - 279 EP - 286 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Höne, Christin T1 - The Musical Novel: Imitation of Musical Structure, Performance and Reception in Contemporary Fiction JF - Geophysical research letters Y1 - 2016 U6 - https://doi.org/10.1093/ml/gcw001 SN - 0027-4224 SN - 1477-4631 VL - 97 SP - 190 EP - 191 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Linnik, Anastasia A1 - Bastiaanse, Roelien A1 - Höhle, Barbara T1 - Discourse production in aphasia: a current review of theoretical and methodological challenges JF - Aphasiology : an international, interdisciplinary journal N2 - Background: Discourse abilities play an important role in the assessment, classification, and therapy outcome evaluation of people with aphasia. Discourse production in aphasia has been studied quite extensively in the last 15 years. Nevertheless, many questions still do not have definitive answers.Aims: The aim of this review is to present the current situation in the research on a number of crucial aspects of discourse production in aphasia, focusing on methodological progress and related challenges. This review continues the discussion of the core themes in the field, aiming to render it as up-to-date as possible.Main Contribution: The review focuses on a number of unexplored theoretical issues, specifically, the interface between micro- and macrolinguistic abilities, and the relationship between linguistic competence and communicative success in aphasia. The emphasis on theoretical challenges, along with the thorough discussion of methodological problems in the field, makes this review a starting point and a comprehensive information source for researchers planning to address language production in people with aphasia.Conclusion: Although the picture is not yet complete, recent advancements lead to a better understanding of the processes involved in aphasic discourse production. Different approaches provide insights into the complex multifaceted nature of discourse-level phenomena; however, methodological issues, including low comparability, substantially slow down the progress in the field. KW - Discourse production KW - aphasia Y1 - 2016 U6 - https://doi.org/10.1080/02687038.2015.1113489 SN - 0268-7038 SN - 1464-5041 VL - 30 SP - 765 EP - 800 PB - Copernicus CY - Abingdon ER - TY - JOUR A1 - Reichetzeder, Christoph A1 - Putra, Sulistyo Emantoko Dwi A1 - Li, Jian A1 - Hocher, Berthold T1 - Developmental Origins of Disease - Crisis Precipitates Change JF - Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry and pharmacology N2 - The concept of developmental origins of diseases has gained a huge interest in recent years and is a constantly emerging scientific field. First observations hereof originated from epidemiological studies, linking impaired birth outcomes to adult chronic, noncommunicable disease. By now there is a considerable amount of both epidemiological and experimental evidence highlighting the impact of early life events on later life disease susceptibility. Albeit far from being completely understood, more recent studies managed to elucidate underlying mechanisms, with epigenetics having become almost synonymous with developmental programming. The aim of this review was to give a comprehensive overview of various aspects and mechanisms of developmental origins of diseases. Starting from initial research foci mainly centered on a nutritionally impaired intrauterine environment, more recent findings such as postnatal nutrition, preterm birth, paternal programming and putative interventional approaches are summarized. The review outlines general underlying mechanisms and particularly discusses mechanistic explanations for sexual dimorphism in developmental programming. Furthermore, novel hypotheses are presented emphasizing a non-mendelian impact of parental genes on the offspring's phenotype. KW - Nutrition KW - Thrifty phenotype KW - Developmental programming KW - Paternal, maternal, sex differences KW - Epigenetics Y1 - 2016 U6 - https://doi.org/10.1159/000447801 SN - 1015-8987 SN - 1421-9778 VL - 39 SP - 919 EP - 938 PB - Karger CY - Basel ER - TY - JOUR A1 - Sternagel, Jörg T1 - Momente des Ethischen. Neuere Literatur zu Maurice Merleau-Ponty JF - Philosophische Rundschau Y1 - 2016 U6 - https://doi.org/10.1628/003181516X14677259134141 SN - 0031-8159 SN - 1868-7261 VL - 63 SP - 143 EP - 159 PB - J. C. B. Mohr CY - Tübingen ER - TY - JOUR A1 - Sternagel, Jörg T1 - Merleau-Ponty and the Experience of the Creation JF - Philosophische Rundschau Y1 - 2016 SN - 0031-8159 SN - 1868-7261 VL - 63 SP - 143 EP - 159 PB - J. C. B. Mohr CY - Tübingen ER - TY - JOUR A1 - Sternagel, Jörg T1 - Identity in an open Reality. A Search for Traces in Connection to Merleau-Ponty, Ricoeur and Waldenfels JF - Philosophische Rundschau Y1 - 2016 SN - 0031-8159 SN - 1868-7261 VL - 63 SP - 143 EP - 159 PB - J. C. B. Mohr CY - Tübingen ER - TY - JOUR A1 - Sternagel, Jörg T1 - To be Pre-occupied. Perception and Physicality with Paul Celan and Maurice Merleau-Ponty JF - Philosophische Rundschau Y1 - 2016 SN - 0031-8159 SN - 1868-7261 VL - 63 SP - 143 EP - 159 PB - J. C. B. Mohr CY - Tübingen ER - TY - JOUR A1 - Gessner, Oliver A1 - Gühr, Markus T1 - Monitoring Ultrafast Chemical Dynamics by Time-Domain X-ray Photo- and Auger-Electron Spectroscopy JF - Accounts of chemical research N2 - The directed flow of charge and energy is at the heart of all chemical processes. Extraordinary efforts are underway to monitor and understand the concerted motion of electrons and nuclei with ever increasing spatial and temporal sensitivity. The element specificity, chemical sensitivity, and temporal resolution of ultrafast X-ray spectroscopy techniques hold great promise to provide new insight into the fundamental interactions underlying chemical dynamics in systems ranging from isolated molecules to application-like devices. Here, we focus on the potential of ultrafast X-ray spectroscopy techniques based on the detection of photo- and Auger electrons to provide new fundamental insight into photochemical processes of systems with various degrees of complexity. Isolated nucleobases provide an excellent testing ground for our most fundamental understanding of intramolecular coupling between electrons and nuclei beyond the traditionally applied Born-Oppenheimer approximation. Ultrafast electronic relaxation dynamics enabled by the breakdown of this approximation is the major component of the nucleobase photoprotection mechanisms. Transient X-ray induced Auger electron spectroscopy on photoexcited thymine molecules provides atomic-site specific details of the extremely efficient coupling that converts potentially bond changing ultraviolet photon energy into benign heat. In particular, the time-dependent spectral shift of a specific Auger band is sensitive to the length of a single bond within the molecule. The X-ray induced Auger transients show evidence for an electronic transition out of the initially excited state within only similar to 200 fs in contrast to theoretically predicted picosecond population trapping behind a reaction barrier. Photoinduced charge transfer dynamics between transition metal complexes and semiconductor nanostructures are of central importance for many emerging energy and climate relevant technologies. Numerous demonstrations of photovoltaic and photocatalytic activity have been performed based on the combination of strong light absorption in dye molecules with charge separation and transport in adjacent semiconductor nanostructures. However, a fundamental understanding of the enabling and limiting dynamics on critical atomic length- and time scales is often still lacking. Femtosecond time-resolved X-ray photoelectron spectroscopy is employed to gain a better understanding of a short-lived intermediate that may be linked to the unexpectedly limited performance of ZnO based dye-sensitized solar cells by delaying the generation of free charge carriers. The transient spectra strongly suggest that photoexcited dye molecules attached to ZnO nanocrystals inject their charges into the substrate within less than 1 ps but the electrons are then temporarily trapped at the surface of the semiconductor in direct vicinity of the injecting molecules. The experiments are extended to monitor the electronic response of the semiconductor substrate to the collective injection from a monolayer of dye molecules and the subsequent electron-ion recombination dynamics. The results indicate some qualitative similarities but quantitative differences between the recombination dynamics at molecule-semiconductor interfaces and previously studied bulk-surface electron-hole recombination dynamics in photoexcited semiconductors. Y1 - 2016 U6 - https://doi.org/10.1021/acs.accounts.5b00361 SN - 0001-4842 SN - 1520-4898 VL - 49 SP - 138 EP - 145 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Wenzel, Bertolt T1 - Organizing coordination in fisheries and marine environmental management: Patterns of organizational change in Europe JF - Bulletin of the Seismological Society of America N2 - Over the past decade, an increasing number of public organizations involved in marine governance in Europe have adapted their formal coordination structures for fisheries and marine environmental management. This study examines why the International Council for the Exploration of the Sea (ICES), DG FISH of the European Commission, the Norwegian Institute of Marine Research (IMR), and the Swedish Agency for Marine and Water Management (SwAM) have changed their sectoral structures into organizations with a geographical focus on marine ecosystems. The study finds that the gradual convergence of formal coordination structures for fisheries and marine environmental management is driven by coercive, normative and mimetic processes of isomorphism. The structural changes reflect an organizational adaptation to a changing institutional environment and an Ecosystem Approach to Management (EAM) focusing on regional marine areas, cross-sector integration and coordination. (C) 2016 Elsevier Ltd. All rights reserved. KW - Public organizations KW - Coordination KW - Fisheries management KW - Marine environmental management KW - Isomorphism Y1 - 2016 U6 - https://doi.org/10.1016/j.ocecoaman.2016.10.012 SN - 0964-5691 SN - 1873-524X VL - 134 SP - 194 EP - 206 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Mahlow, Sebastian A1 - Orzechowski, Slawomir A1 - Fettke, Jörg T1 - Starch phosphorylation: insights and perspectives JF - Cellular and molecular life sciences N2 - During starch metabolism, the phosphorylation of glucosyl residues of starch, to be more precise of amylopectin, is a repeatedly observed process. This phosphorylation is mediated by dikinases, the glucan, water dikinase (GWD) and the phosphoglucan, water dikinase (PWD). The starch-related dikinases utilize ATP as dual phosphate donor transferring the terminal gamma-phosphate group to water and the beta-phosphate group selectively to either C6 position or C3 position of a glucosyl residue within amylopectin. By the collaborative action of both enzymes, the initiation of a transition of alpha-glucans from highly ordered, water-insoluble state to a less order state is realized and thus the initial process of starch degradation. Consequently, mutants lacking either GWD or PWD reveal a starch excess phenotype as well as growth retardation. In this review, we focus on the increased knowledge collected over the last years related to enzymatic properties, the precise definition of the substrates, the physiological implications, and discuss ongoing questions. KW - Starch metabolism KW - Glucan, water dikinase KW - Phosphoglucan, water dikinase KW - Starch phosphorylation KW - Starch degradation Y1 - 2016 U6 - https://doi.org/10.1007/s00018-016-2248-4 SN - 1420-682X SN - 1420-9071 VL - 73 SP - 2753 EP - 2764 PB - Springer CY - Basel ER - TY - JOUR A1 - Spahn, Hannah T1 - Republican, and a Tea Party Fanatic, All the While Being Dead JF - The American historical review Y1 - 2016 U6 - https://doi.org/10.1093/ahr/121.3.933 SN - 0002-8762 SN - 1937-5239 VL - 121 SP - 933 EP - 934 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Rauch, Bernhard A1 - Davos, Constantinos H. A1 - Doherty, Patrick A1 - Saure, Daniel A1 - Metzendorf, Maria-Inti A1 - Salzwedel, Annett A1 - Völler, Heinz A1 - Jensen, Katrin A1 - Schmid, Jean-Paul T1 - The prognostic effect of cardiac rehabilitation in the era of acute revascularisation and statin therapy: A systematic review and meta-analysis of randomized and non-randomized studies - The Cardiac Rehabilitation Outcome Study (CROS) JF - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology N2 - Background The prognostic effect of multi-component cardiac rehabilitation (CR) in the modern era of statins and acute revascularisation remains controversial. Focusing on actual clinical practice, the aim was to evaluate the effect of CR on total mortality and other clinical endpoints after an acute coronary event. Design Structured review and meta-analysis. Methods Randomised controlled trials (RCTs), retrospective controlled cohort studies (rCCSs) and prospective controlled cohort studies (pCCSs) evaluating patients after acute coronary syndrome (ACS), coronary artery bypass grafting (CABG) or mixed populations with coronary artery disease (CAD) were included, provided the index event was in 1995 or later. Results Out of n=18,534 abstracts, 25 studies were identified for final evaluation (RCT: n=1; pCCS: n=7; rCCS: n=17), including n=219,702 patients (after ACS: n=46,338; after CABG: n=14,583; mixed populations: n=158,781; mean follow-up: 40 months). Heterogeneity in design, biometrical assessment of results and potential confounders was evident. CCSs evaluating ACS patients showed a significantly reduced mortality for CR participants (pCCS: hazard ratio (HR) 0.37, 95% confidence interval (CI) 0.20-0.69; rCCS: HR 0.64, 95% CI 0.49-0.84; odds ratio 0.20, 95% CI 0.08-0.48), but the single RCT fulfilling Cardiac Rehabilitation Outcome Study (CROS) inclusion criteria showed neutral results. CR participation was also associated with reduced mortality after CABG (rCCS: HR 0.62, 95% CI 0.54-0.70) and in mixed CAD populations. Conclusions CR participation after ACS and CABG is associated with reduced mortality even in the modern era of CAD treatment. However, the heterogeneity of study designs and CR programmes highlights the need for defining internationally accepted standards in CR delivery and scientific evaluation. KW - Rehabilitation KW - acute coronary syndrome KW - coronary bypass grafting KW - coronary artery disease KW - mortality KW - hospital readmission Y1 - 2016 U6 - https://doi.org/10.1177/2047487316671181 SN - 2047-4873 SN - 2047-4881 VL - 23 SP - 1914 EP - 1939 PB - Sage Publ. CY - London ER - TY - JOUR A1 - Metzler, Ralf A1 - Jeon, J. -H. A1 - Cherstvy, Andrey G. T1 - Non-Brownian diffusion in lipid membranes: Experiments and simulations JF - Biochimica et biophysica acta : Biomembranes N2 - The dynamics of constituents and the surface response of cellular membranes also in connection to the binding of various particles and macromolecules to the membrane are still a matter of controversy in the membrane biophysics community, particularly with respect to crowded membranes of living biological cells. We here put into perspective recent single particle tracking experiments in the plasma membranes of living cells and supercomputing studies of lipid bilayer model membranes with and without protein crowding. Special emphasis is put on the observation of anomalous, non-Brownian diffusion of both lipid molecules and proteins embedded in the lipid bilayer. While single component, pure lipid bilayers in simulations exhibit only transient anomalous diffusion of lipid molecules on nanosecond time scales, the persistence of anomalous diffusion becomes significantly longer ranged on the addition of disorder through the addition of cholesterol or proteins and on passing of the membrane lipids to the gel phase. Concurrently, experiments demonstrate the anomalous diffusion of membrane embedded proteins up to macroscopic time scales in the minute time range. Particular emphasis will be put on the physical character of the anomalous diffusion, in particular, the occurrence of ageing observed in the experiments the effective diffusivity of the measured particles is a decreasing function of time. Moreover, we present results for the time dependent local scaling exponent of the mean squared displacement of the monitored particles. Recent results finding deviations from the commonly assumed Gaussian diffusion patterns in protein crowded membranes are reported. The properties of the displacement autocorrelation function of the lipid molecules are discussed in the light of their appropriate physical anomalous diffusion models, both for non-crowded and crowded membranes. In the last part of this review we address the upcoming field of membrane distortion by elongated membrane-binding particles. We discuss how membrane compartmentalisation and the particle-membrane binding energy may impact the dynamics and response of lipid membranes. This article is part of a Special Issue entitled: Biosimulations edited by Ilpo Vattulainen and Tomasz Rog. (C) 2016 The Authors. Published by Elsevier B.V. KW - Lipid bilayer KW - Protein crowding KW - Anomalous diffusion KW - Simulations KW - Stochastic modelling KW - Non-Gaussian Y1 - 2016 U6 - https://doi.org/10.1016/j.bbamem.2016.01.022 SN - 0005-2736 SN - 0006-3002 VL - 1858 SP - 2451 EP - 2467 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Speller, Camilla A1 - van den Hurk, Youri A1 - Charpentier, Anne A1 - Rodrigues, Ana A1 - Gardeisen, Armelle A1 - Wilkens, Barbara A1 - McGrath, Krista A1 - Rowsell, Keri A1 - Spindler, Luke A1 - Collins, Matthew J. A1 - Hofreiter, Michael T1 - Barcoding the largest animals on Earth: ongoing challenges and molecular solutions in the taxonomic identification of ancient cetaceans JF - Philosophical transactions of the Royal Society of London : B, Biological sciences KW - ancient DNA KW - archaeozoology KW - cetaceans KW - collagen peptide mass fingerprinting KW - species identification KW - zooarchaeology by mass spectrometry Y1 - 2016 U6 - https://doi.org/10.1098/rstb.2015.0332 SN - 0962-8436 SN - 1471-2970 VL - 371 PB - Royal Society CY - London ER - TY - JOUR A1 - Schumacher, Reinhard T1 - Propriety and Prosperity: New Studies on the Philosophy of Adam Smith, Archival Insights Into the Evolution of Economics JF - Journal of behavioral and experimental economics Y1 - 2016 U6 - https://doi.org/10.1016/j.socec.2016.02.002 SN - 2214-8043 SN - 2214-8051 VL - 62 SP - 51 EP - 52 PB - Elsevier CY - New York ER - TY - JOUR A1 - Bacskai-Atkari, Julia T1 - Syntax over Time. Lexical, Morphological, and Information - Structural Interactions JF - Beiträge zur Geschichte der deutschen Sprache und Literatur Y1 - 2016 U6 - https://doi.org/10.1515/bgsl-2016-0020 SN - 0005-8076 SN - 1865-9373 VL - 138 SP - 264 EP - 271 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Seidel, Esther T1 - The Vision of another Kind of Judaism: Selected Writings JF - Plant Methods Y1 - 2016 SN - 0031-8221 SN - 1527-943X VL - 66 SP - 685 EP - 694 PB - University of Hawaii Press CY - Honolulu ER - TY - JOUR A1 - Seidel, Esther T1 - Germany or Jerusalem: The short Life of Francesca Albertini JF - Ecological modelling : international journal on ecological modelling and engineering and systems ecolog Y1 - 2016 SN - 0031-8221 SN - 1527-943X VL - 66 SP - 685 EP - 694 PB - University of Hawaii Press CY - Honolulu ER - TY - JOUR A1 - Pearson, Leanne A. A1 - Dittmann, Elke A1 - Mazmouz, Rabia A1 - Ongley, Sarah E. A1 - Neilan, Brett A. T1 - The genetics, biosynthesis and regulation of toxic specialized metabolites of cyanobacteria JF - Harmful algae N2 - The production of toxic metabolites by cyanobacterial blooms represents a significant threat to the health of humans and ecosystems worldwide. Here we summarize the current state of the knowledge regarding the genetics, biosynthesis and regulation of well-characterized cyanotoxins, including the microcystins, nodularin, cylindrospermopsin, saxitoxins and antitoxins, as well as the lesser-known marine toxins (e.g. lyngbyatoxin, aplysiatoxin, jamaicamides, barbamide, curacin, hectochlorin and apratoxins). (C) 2015 Elsevier B.V. All rights reserved. KW - Cyanobacteria KW - Cyanotoxins KW - Specialized metabolites KW - Genetics KW - Biosynthesis KW - Regulation Y1 - 2016 U6 - https://doi.org/10.1016/j.hal.2015.11.002 SN - 1568-9883 SN - 1878-1470 VL - 54 SP - 98 EP - 111 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Rajasundaram, Dhivyaa A1 - Selbig, Joachim T1 - analysis JF - Current opinion in plant biology N2 - The development of ‘omics’ technologies has progressed to address complex biological questions that underlie various plant functions thereby producing copious amounts of data. The need to assimilate large amounts of data into biologically meaningful interpretations has necessitated the development of statistical methods to integrate multidimensional information. Throughout this review, we provide examples of recent outcomes of ‘omics’ data integration together with an overview of available statistical methods and tools. Y1 - 2016 U6 - https://doi.org/10.1016/j.pbi.2015.12.010 SN - 1369-5266 SN - 1879-0356 VL - 30 SP - 57 EP - 61 PB - Elsevier CY - London ER - TY - JOUR A1 - Goychuk, Igor T1 - Molecular machines operating on the nanoscale: from classical to quantum JF - Beilstein journal of nanotechnology N2 - The main physical features and operating principles of isothermal nanomachines in the microworld, common to both classical and quantum machines, are reviewed. Special attention is paid to the dual, constructive role of dissipation and thermal fluctuations, the fluctuation-dissipation theorem, heat losses and free energy transduction, thermodynamic efficiency, and thermodynamic efficiency at maximum power. Several basic models are considered and discussed to highlight generic physical features. This work examines some common fallacies that continue to plague the literature. In particular, the erroneous beliefs that one should minimize friction and lower the temperature for high performance of Brownian machines, and that the thermodynamic efficiency at maximum power cannot exceed one-half are discussed. The emerging topic of anomalous molecular motors operating subdiffusively but very efficiently in the viscoelastic environment of living cells is also discussed. KW - anomalous dynamics with memory KW - Brownian nanomachines KW - nanoscale friction and thermal noise KW - quantum effects KW - thermodynamic efficiency Y1 - 2016 U6 - https://doi.org/10.3762/bjnano.7.31 SN - 2190-4286 VL - 7 SP - 328 EP - 350 PB - Beilstein-Institut zur Förderung der Chemischen Wissenschaften CY - Frankfurt, Main ER - TY - JOUR A1 - Reimer, Anna Maria T1 - Identitas Oriens: Discursive Constructions of Identity and Alterity in British Orient Travelogues JF - Zeitschrift für Anglistik und Amerikanistik : a quarterly of language, literature and cultur Y1 - 2016 U6 - https://doi.org/10.1515/zaa-2016-0010 SN - 0044-2305 SN - 2196-4726 VL - 64 SP - 112 EP - 114 PB - De Gruyter CY - Berlin ER - TY - JOUR A1 - Omerbasic, Alina T1 - The Non-Identity Problem and the Ethics of Future People JF - Ethical theory and moral practice Y1 - 2016 U6 - https://doi.org/10.1007/s10677-015-9614-4 SN - 1386-2820 SN - 1572-8447 VL - 19 SP - 273 EP - 275 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Leimkühler, Silke A1 - Iobbi-Nivol, Chantal T1 - Bacterial molybdoenzymes: old enzymes for new purposes JF - FEMS microbiology reviews N2 - Molybdoenzymes are widespread in eukaryotic and prokaryotic organisms where they play crucial functions in detoxification reactions in the metabolism of humans and bacteria, in nitrate assimilation in plants and in anaerobic respiration in bacteria. To be fully active, these enzymes require complex molybdenum-containing cofactors, which are inserted into the apoenzymes after folding. For almost all the bacterial molybdoenzymes, molybdenum cofactor insertion requires the involvement of specific chaperones. In this review, an overview on the molybdenum cofactor biosynthetic pathway is given together with the role of specific chaperones dedicated for molybdenum cofactor insertion and maturation. Many bacteria are involved in geochemical cycles on earth and therefore have an environmental impact. The roles of molybdoenzymes in bioremediation and for environmental applications are presented.This review gives an overview of the diverse mechanisms leading to the insertion of the different forms of the molybdenum cofactor into the respective target enzymes and summarizes the roles of different molybdoenzymes in the environment.This review gives an overview of the diverse mechanisms leading to the insertion of the different forms of the molybdenum cofactor into the respective target enzymes and summarizes the roles of different molybdoenzymes in the environment. KW - molybdenum cofactor KW - specific chaperons KW - TorD family KW - XdhC KW - molybdoenzyme maturation KW - bioremediation Y1 - 2016 U6 - https://doi.org/10.1093/femsre/fuv043 SN - 0168-6445 SN - 1574-6976 VL - 40 SP - 1 EP - 18 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Pourteau, Amaury A1 - Oberhänsli, Roland A1 - Candan, Osman A1 - Barrier, Eric A1 - Vrielynck, Bruno T1 - Neotethyan closure history of western Anatolia: a geodynamic discussion JF - International journal of earth sciences N2 - This paper addresses the lithosphere-scale subduction-collision history of the eastern termination of the Aegean retreating subduction system, i.e. western Anatolia. Although there is some general consensus on the protracted subduction evolution of the Aegean since the early Cenozoic at least, correlation with western Anatolia has been widely debated for more than several decades. In western Anatolia, three main tectonic configurations have been envisaged in the past years to reconstruct slab dynamics during the closure of the Neotethyan oceanic realm since the Late Cretaceous. Some authors have suggested an Aegean-type scenario, with the continuous subduction of a single lithospheric slab, punctuated by episodic slab roll-back and trench retreat, whereas others assumed a discontinuous subduction history marked by intermittent slab break-off during either the Campanian (ca. 75 Ma) or the Early Eocene (ca. 55-50 Ma). The third view implies three partly contemporaneous subduction zones. Our review of these models points to key debated aspects that can be re-evaluated in the light of multidisciplinary constraints from the literature. Our discussion leads us to address the timing of subduction initiation, the existence of hypothetical ocean basins, the number of intervening subduction zones between the Taurides and the Pontides, the palaeogeographic origin of tectonic units and the possibility for slab break-off during either the Campanian or the Early Eocene. Thence, we put forward a favoured tectonic scenario featuring two successive phases of subduction of a single lithospheric slab and episodic accretion of two continental domains separated by a continental trough, representing the eastern end of the Cycladic Ocean of the Aegean. The lack of univocal evidence for slab break-off in western Anatolia and southward-younging HP/LT metamorphism in continental tectonic units (from similar to 85, 70 to 50 Ma) in the Late Cretaceous-Palaeogene period suggests continuous subduction since similar to 110 Ma, marked by roll-back episodes in the Palaeocene and the Oligo-Miocene, and slab tearing below western Anatolia during the Miocene. KW - Subduction KW - Anatolia KW - Aegean KW - Neotethys KW - Slab break-off KW - Slab roll-back Y1 - 2016 U6 - https://doi.org/10.1007/s00531-015-1226-7 SN - 1437-3254 SN - 1437-3262 VL - 105 SP - 203 EP - 224 PB - Springer CY - New York ER - TY - JOUR A1 - Warschburger, Petra T1 - Overweight and Obesity JF - Zeitschrift für Klinische Psychologie und Psychotherapie Y1 - 2016 U6 - https://doi.org/10.1026/1616-3443/a000347 SN - 1616-3443 SN - 2190-6297 VL - 45 SP - 64 EP - 65 PB - Routledge, Taylor & Francis Group CY - Göttingen ER - TY - JOUR A1 - Wyrwa, Ulrich T1 - Jewish Life between East and West. New Contributions on the jewish History in Schlesien JF - Deutsche Zeitschrift für Geschichtswissenschaft Y1 - 2016 SN - 0044-2828 SN - 1618-0372 VL - 64 SP - 76 EP - 78 PB - Metropol-Verl. CY - Berlin ER - TY - JOUR A1 - Woodhouse, Jason Nicholas A1 - Makower, A. Katharina A1 - Yeung, Anna C. Y. A1 - Ongley, Sarah E. A1 - Micallef, Melinda L. A1 - Moffitt, Michelle C. A1 - Neilan, Brett A. T1 - Advances in genomics, transcriptomics and proteomics of toxin-producing cyanobacteria JF - Environmental microbiology reports N2 - A common misconception persists that the genomes of toxic and non-toxic cyanobacterial strains are largely conserved with the exception of the presence or absence of the genes responsible for toxin production. Implementation of -omics era technologies has challenged this paradigm, with comparative analyses providing increased insight into the differences between strains of the same species. The implementation of genomic, transcriptomic and proteomic approaches has revealed distinct profiles between toxin-producing and non-toxic strains. Further, metagenomics and metaproteomics highlight the genomic potential and functional state of toxic bloom events over time. In this review, we highlight how these technologies have shaped our understanding of the complex relationship between these molecules, their producers and the environment at large within which they persist. Y1 - 2016 U6 - https://doi.org/10.1111/1758-2229.12366 SN - 1758-2229 VL - 8 SP - 3 EP - 13 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Denz, Rebekka T1 - Anne-Katrin Henkel / Thomas Rahe (Hrsg.): Publizistik in jüdischen Displaced- Persons-Camps. Charakteristika, Medien und bibliothekarische Überlieferung / rezensiert von Rebekka Denz JF - PaRDeS : Zeitschrift der Vereinigung für Jüdische Studien [22 (2016)] = Muslim-Jewish Dialogue JF - PaRDeS : Journal of the Association of Jewish Studies [22 (2016)] = Muslim-Jewish Dialogue N2 - Rezensiertes Werk: Anne-Katrin Henkel / Thomas Rahe (Hrsg.): Publizistik in jüdischen Displaced-Persons-Camps. Charakteristika, Medien und bibliothekarische Überlieferung, Zeitschrift für Bibliothekswesen und Bibliographie. Sonderbände, Bd. 112, Frankfurt am Main: Vittorio Klostermann Verlag 2014. 194 S. Y1 - 2016 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-99894 SN - 978-3-86956-370-1 SN - 1614-6492 SN - 1862-7684 VL - 22 SP - 252 EP - 255 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Mielke, Jahel A1 - Vermassen, Hannah A1 - Ellenbeck, Saskia A1 - Milan, Blanca Fernandez A1 - Jaeger, Carlo T1 - Stakeholder involvement in sustainability science-A critical view JF - Global biogeochemical cycles N2 - Discussions about the opening of science to society have led to the emergence of new fields such as sustainability science and transformative science. At the same time, the megatrend of stakeholder participation reached the academic world and thus scientific research processes. This challenges the way science is conducted and the tools, methods and theories perceived appropriate. Although researchers involve stakeholders, the scientific community still lacks comprehensive theoretical analysis of the practical processes behind their integration - for example what kind of perceptions scientists have about their roles, their objectives, the knowledge to gather, their understanding of science or the science-policy interface. Our paper addresses this research gap by developing four ideal types of stakeholder involvement in science - the technocratic, the functionalist, the neoliberal-rational and the democratic type. In applying the typology, which is based on literature review, interviews and practical experiences, we identify and discuss three major criticisms raised towards stakeholder involvement in science: the legitimacy of stakeholder claims, the question whether bargaining or deliberation are part of the stakeholder involvement process and the question of the autonomy of science. Thus, the typology helps scientists to better understand the major critical questions that stakeholder involvement raises and enables them to position themselves when conducting their research. (C) 2016 Elsevier Ltd. All rights reserved. KW - Sustainability science KW - Stakeholder involvement typology KW - Energy transition KW - Transformative research Y1 - 2016 U6 - https://doi.org/10.1016/j.erss.2016.04.001 SN - 2214-6296 SN - 2214-6326 VL - 17 SP - 71 EP - 81 PB - Elsevier CY - Amsterdam ER -