TY  - JOUR
A1  - Zhou, Qihui
A1  - Wuennemann, Patrick
A1  - Kuhn, Philipp Till
A1  - de Vries, Joop
A1  - Helmin, Marta
A1  - Böker, Alexander
A1  - van Kooten, Theo G.
A1  - van Rijn, Patrick
T1  - Mechanical Properties of Aligned Nanotopologies for Directing Cellular Behavior
JF  - Advanced materials interfaces
N2  - Tailoring cell–surface interactions is important for the of design medical implants as well as regenerative medicine and tissue engineering materials. Here the single parameter system is transcended via translating hard nanotopology into soft polymeric hydrogel structures via hydrogel imprinting lithography. The response of these cells to the nanotopology of the same dimensions but with different mechanical properties displays unexpected behavior between “hard” tissue cells and “soft” tissue cells.
Y1  - 2016
U6  - https://doi.org/10.1002/admi.201600275
SN  - 2196-7350
VL  - 3
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - JOUR
A1  - Wuennemann, Patrick
A1  - Noyong, Michael
A1  - Kreuels, Klaus
A1  - Bruex, Roland
A1  - Gordiichuk, Pavlo
A1  - van Rijn, Patrick
A1  - Plamper, Felix A.
A1  - Simon, Ulrich
A1  - Böker, Alexander
T1  - Microstructured Hydrogel Templates for the Formation of Conductive Gold Nanowire Arrays
JF  - Macromolecular rapid communications
N2  - Microstructured hydrogel allows for a new template-guided method to obtain conductive nanowire arrays on a large scale. To generate the template, an imprinting process is used in order to synthesize the hydrogel directly into the grooves of wrinkled polydimethylsiloxane (PDMS). The resulting poly(N-vinylimidazole)-based hydrogel is defined by the PDMS stamp in pattern and size. Subsequently, tetrachloroaurate(III) ions from aqueous solution are coordinated within the humps of the N-vinylimidazole-containing polymer template and reduced by air plasma. After reduction and development of the gold, to achieve conductive wires, the extension perpendicular to the long axis (width) of the gold strings is considerably reduced compared to the dimension of the parental hydrogel wrinkles (from approximate to 1 mu m down to 200-300 nm). At the same time, the wire-to-wire distance and the overall length of the wires is preserved. The PDMS templates and hydrogel structures are analyzed with scanning force microscopy (SFM) and the gold structures via scanning electron microscopy (SEM) and energy-dispersive X-ray spectroscopy. The conductivity measurements of the gold nanowires are performed in situ in the SEM, showing highly conductive gold leads. Hence, this method can be regarded as a facile nonlithographic top-down approach from micrometer-sized structures to nanometer-sized features.
KW  - 1D structures
KW  - Au nanoarrays
KW  - microgel
KW  - nanoimprint
KW  - lithography
KW  - thin films
Y1  - 2016
U6  - https://doi.org/10.1002/marc.201600287
SN  - 1022-1336
SN  - 1521-3927
VL  - 37
SP  - 1446
EP  - 1452
PB  - Wiley-VCH
CY  - Weinheim
ER  -