TY - JOUR A1 - Dunst, Alexander T1 - "After trauma : time and affect in american culture beyond 9/11" Y1 - 2012 SN - 1353-4645 ER - TY - JOUR A1 - Warschburger, Petra A1 - Kröller, Katja T1 - "Childhood overweight and obesity maternal perceptions of the time for engaging in child weight management" JF - BMC public health N2 - Background: There is an increasing awareness of the impact of parental risk perception on the weight course of the child and the parent's readiness to engage in preventive efforts, but only less is known about factors related to the parental perception of the right time for the implementation of preventive activities. The aim of this study was to examine parental perceptions of the appropriate time to engage in child weight management strategies, and the factors associated with different weight points at which mothers recognize the need for preventive actions. Methods: 352 mothers with children aged 2-10 years took part in the study. We assessed mothers' perceptions of the actual and preferred weight status of their child, their ability to identify overweight and knowledge of its associated health risks, as well as perceptions of the right time for action to prevent overweight in their child. A regression analysis was conducted to examine whether demographic and weight related factors as well as the maternal general risk perception were associated with recognizing the need to implement prevention strategies. Results: Although most of the parents considered a BMI in the 75th to 90th percentile a valid reason to engage in the prevention of overweight, 19% of the mothers were not willing to engage in prevention until their child reached the 97th percentile. Whereas the child's sex and the identification of an elevated BMI were significant predictors for parents' recognition of the 75th percentile as right point to engage in prevention efforts, an inability to recognize physical health risks associated with overweight silhouettes emerged as a significant factor predicting which parents would delay prevention efforts until a child's BMI reached the 97th percentile. Conclusion: Parental misperceptions of overweight and associated health risks constitute unfavorable conditions for preventive actions. Feedback on the health risks associated with overweight could help increase maternal readiness for change. KW - Maternal perception KW - Need for action KW - Prevention KW - Obesity KW - Overweight KW - Children Y1 - 2012 U6 - https://doi.org/10.1186/1471-2458-12-295 SN - 1471-2458 VL - 12 IS - 12 PB - BioMed Central CY - London ER - TY - JOUR A1 - Schröder, Ariane T1 - "Descent into hell" : the cultural and biomedical signification of depression in William Styron's "Darkness Visible" Y1 - 2012 SN - 978-3-631-63614-5 ER - TY - JOUR A1 - Holl, Frank T1 - "Die zweitgrößte Beleidigung des Menschen sei die Sklaverei ..." BT - Daniel Kehlmanns neu erfundener Alexander von Humboldt N2 - Daniel Kehlmann gibt vor, mit seinem Roman Die Vermessung der Welt „verschwiegene oder übersehene Wahrheiten sichtbar“ zu machen. Dadurch, dass er die Leser bewusst im Zweifel lässt, was historisch belegt und was erfunden ist, entstehen Missverständnisse. Der Beitrag analysiert die wichtigsten Charakteristika des Kehlmann‘schen und des historischen Alexander von Humboldt und weist nach, dass diese nicht übereinstimmen. Der Aufsatz fragt nach Kehlmanns Rolle, der in der Öffentlichkeit gerne die Pose des Gelehrten einnimmt, seine Erfindungen jedoch nicht offenlegt und sie als angebliches Humboldt-Zitat sogar in einem wissenschaftlichen Text publiziert. Der Beitrag kommt zu dem Schluss, dass alle, die etwas für ihre Allgemeinbildung tun möchten, bei Die Vermessung der Welt an der falschen Adresse sind. N2 - With his novel Measuring the World, Daniel Kehlmann pretends „to make visible a reticent and ignored truth“. In leaving the reader intentionally in doubt about what is historically proven and what is invented, Kehlmann’s book prompts misreadings. The article compares the main traits of the „Kehlmannian“ against those of the historical Alexander von Humboldt and documents their mis-matching in some central attributes. Moreover, Kehlmann‘s public and self-declared role as an informed scholar is questioned, especially when he uses fictional Humboldt quotes as if they were a matter of fact (i.e. as part of a foreword to a recent text edition on Charles Darwin). The article comes to the conclusion that those interested in general historical knowledge should not take this novel very seriously. N2 - Con su novela La medición del mundo Daniel Kehlmann pretende “de hacer visible una verdad callada e ignorada”. Pero esa verdad es tramposa. El libro de Kehlmann intencionalmente provoca confusiones sobre lo que son los hechos históricos y lo que es pura ficción. Por ende, el artículo compara las principales características del Humboldt “kehlmanniado” con la figura histórica y comprueba sus más evidentes incongruencias. Además, se cuestiona el papel público del auto-declarado erúdito e informado autor Kehlmann, por ejemplo cuando éste introduce – sin declararlo – citas fictícias de Humboldt al prólogo de una edición reciente con textos de Charles Darwin. Con todo eso, el artículo llega a la conclusión de que todos aquellos interesados en conocimiento general histórico no deberían tomar la novela en serio. KW - Carl Friedrich Gauß KW - Daniel Kehlmann KW - Die Vermessung der Welt KW - Schwerpunktthema „À propos Kehlmann“ Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-62413 SN - 1617-5239 SN - 2568-3543 VL - XIII IS - 25 SP - 46 EP - 62 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Berner, Elisabeth T1 - "Erst wusste ich nicht, was tun …" BT - Das Tagebuch des Dawid Rubinowicz JF - Vielheit und Einheit der Germanistik weltweit Y1 - 2013 SN - 978-3-631-63211-6 IS - 11 SP - 189 EP - 203 PB - Lang CY - Frankfurt am Main ER - TY - JOUR A1 - Dornick, Sahra T1 - "Footnotes to the Family" Performativity to the trauma of the Holocaust in the German-Jewish Family novels "So are we" (Gila Lustiger) and "Family Life" (Viola Roggenkamp) JF - Zeitschrift für Religions- und Geistesgeschichte Y1 - 2012 SN - 0044-3441 VL - 64 IS - 2 SP - 138 EP - 151 PB - Brill CY - Leiden ER - TY - JOUR A1 - Stockhorst, Stefanie T1 - "Geiles 17. Jahrhundert" : zur Barock-Rezeption Thomas Klings Y1 - 2012 SN - 978-3-389971-874-4 ER - TY - JOUR A1 - Szelat, Sebastian A1 - Wehr, Katharina T1 - "Military history editions today new challenges, old problems?" Workshop of the military history research institute, 1-2 June 2012 in Potsdam JF - Militärgeschichtliche Zeitschrift Y1 - 2012 SN - 2193-2336 VL - 71 IS - 2 SP - 398 EP - 402 PB - De Gruyter Oldenbourg CY - Potsdam ER - TY - JOUR A1 - Peters, Friedrich Ernst T1 - "O du fröhliche ..." JF - Digitale Edition: Friedrich Ernst Peters N2 - Der Begriff „Kindjees“ (Kind Jesus) bezeichnete lange Zeit in ländlichen Gegenden Norddeutschlands den Weihnachtsmann. Peters erinnert sich hier an die Weihnachtsbräuche seiner Kindheit und schildert gleichzeitig die eigene Entwicklung von dem blind der Macht des Kindjees vertrauenden Knaben zu dem Friedrich Schiller verehrenden Vierzehnjährigen, der selbst für die Kleineren die Rolle des Kindjees übernimmt. Die Schönheit der in der Schule gesungenen Kirchenlieder von Gerhard Tersteegen, die Faszination der Kinder für die Neuruppiner Bilderbogen (plattdeutsch: Lex) tragen viel zu der märchenhaften Stimmung bei, in der die Weihnachtsvorbereitungen in Luhnstedt, dem Heimatdorf des Dichters, stattfinden: „Überhaupt kam es vor Weihnachten sehr darauf an, alles, auch das Geringste, in der vertrauten Form wiederkehren zu lassen, Tradition zu schaffen. Die periodische, unbedingt gleichförmige Wiederkehr äußerer Ereignisse ist eine Quelle der Poesie.“ KW - Tersteegen KW - Gerhard KW - Weihnachtsbrauch KW - Luhnstedt KW - Neuruppin KW - Bilderbogen KW - Tersteegen KW - Gerhard KW - Christmas tradition KW - Luhnstedt KW - Neuruppin KW - sheet of pictures Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-59605 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Peters, Friedrich Ernst T1 - "Staken und Bretter" JF - Digitale Edition : Friedrich Peters N2 - Eine aus der 1975 posthum veröffentlichten "Baasdörper Krönk" entwickelte Geschichte, die F.E. Peters in hochdeutscher Sprache veröffentlicht hat. Es geht um die Liebesgeschichte, aber auch den kleinen Machtkampf zwischen einem verwitweten Bauern mit vier Kindern und seiner Haushälterin, die für den Geschmack des angehenden Ehemannes zu viel Wert auf Äußerlichkeiten legt. „Staken und Bretter dienen dazu, das Fassungsvermögen eines Leiterwagens zu steigern.“ Der Ausdruck wird in Baasdorf im übertragenen Sinn für Anzeichen eines übertriebenen Geltungsbedürfnisses gebraucht. Berühmt ist die zu der Erzählung gehörende Episode aus der "Baasdörper Krönk" wegen des Ausspruchs von Johann-Detlef: „Dar fohrt Puls [hier: Thun] mit Tante längs.“ (Krönk, S. 67, Staken und Bretter, S. 8). In der "Krönk" folgen sprachsoziologisch interessante Ausführungen des Erzählers zu den vier Gründen, warum der Ausspruch von Johann-Detlef, der die Geziertheit der Haushälterin parodiert, im Dorf zu einem Lacherfolg wird. Nach Baasdorfer Meinung heißt es „föhrt“ und nicht „fahrt“, außerdem „lang“ und nicht „längs“. Zu allem Überfluss lässt sich die Haushälterin von den Kindern „Tante“ nennen, „wat ok dumm Tüüch weer“ und schließlich nennt sie Hansjörn Puls (hier: Ehler Thun) beim Nachnamen. Johann-Detlef macht also mit seinem Spott mobil gegen die Haushälterin, denn der Gebrauch des Hochdeutschen wird in Baasdorf als ein Zeichen von Hochnäsigkeit gewertet: „So’n Lö, de – mit een Woort geseggt – ümmer höger schieten wüllt, as se den Mors hebbt, de nehmt wi erst mal en betjen in’e Maak; de mööt erstmal wat ümlehren.“ (Krönk, S. 67). In der "Krönk" geht der sich später fortsetzende eheliche Kampf um „Staken und Bretter“ anders und weniger harmonisch aus als in der Erzählung. KW - Eitelkeit KW - Baasdörper Krönk KW - vanity KW - Baasdörper Krönk Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-57717 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Schwarz, Anja T1 - "That's not a story i could tell" : commemorating the other side of the colonial frontier in Australian literature of reconciliation Y1 - 2012 SN - 978-0-230-30200-6 ER - TY - JOUR A1 - Peters, Friedrich Ernst T1 - "Ulenspegel un Jan Dood" BT - die Gestalt eines Dichters in Niederdeutschland JF - Digitale Edition : Friedrich Peters N2 - Charakterisierung des literarischen Schaffens von Moritz Jahn. Seine Bedeutung für das Plattdeutsche. F. E. Peters beschreibt, Moritz Jahn humorvoll folgend, "polare Spannungen" in Niederdeutschland: "Es gibt Niederdeutsche, die ihrem Lande nie so ganz trauen, die daheim in einer immerwährenden leisen Unruhe hinleben und die aufatmen, wenn sie in gebirgiger Gegend das nackte Gestein unter ihren Füßen fühlen. Dann wird klar, was sie sich bis dahin mühsam verhehlt haben: dass sie nämlich in einem geheimen Winkel ihrer Seele glauben, ihr Land sei vom Meere unterspült, könne an besonders dünnen Stellen durchbrechen, vom festen Kern der Erde losgerissen werden und in die Nebel der Unendlichkeit hinaustreiben. Auf felsigem Grund werden sie dann die neue und wohltuende Sicherheit mit großer Freude so lange genießen, bis das unwiderstehliche Heimweh sie zurücktreibt in die Unsicherheit." KW - Jahn KW - Moritz KW - Plattdeutsch KW - Niederdeutsch KW - Jahn KW - Moritz KW - Low German Y1 - 2012 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-58086 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Sutton, Katie T1 - "We too deserve a place in the sun" the politics of transvestiteidentity in Weimar Germany JF - German studies review N2 - Cross-dressing took on new political meanings in Germany's Weimar Republic, with the emergence of organizations and periodicals aimed at promoting the interests of self-identified "transvestites." This new sexological category, developed by Magnus Hirschfeld in 1910, formed the basis for a shared sense of identity and belonging among individuals who identified as members of the "opposite" sex. Drawing on the experiences of the homosexual emancipation movement and discourses of bourgeois respectability, middle-class transvestites came together to demand legal and social recognition, including acknowledgement of "transsexual" desires. Their efforts represent a critical but forgotten moment in the history of transgender political activism. Y1 - 2012 SN - 0149-7952 VL - 35 IS - 2 SP - 335 EP - 354 PB - Johns Hopkins Univ. Press CY - Tempe ER - TY - JOUR A1 - Eckstein, Lars T1 - "We're destroyed if we mix : and we're destroyed if we don't" : indigeneity in the modern world system and the politics of tricksterese in Pauline Melville's the ventriloquist's tale Y1 - 2012 SN - 978-3-938944- 60-8 ER - TY - JOUR A1 - Raphael-Hernandez, Heike T1 - 'Yes, I will blow up this place, but first I have my coffee.' Representations of Arab Americans in post-9/11 American Films Y1 - 2012 SN - 978-38-2553-5891-4 ER - TY - JOUR A1 - Göse, Frank T1 - ... die Racce davon so guht ist, das sie auf alle art meritiret, conserviret zu werden : das Verhältnis Friedrichs des Grossen zum brandenburgischen Adel Y1 - 2012 SN - 978-3-86732-138-9 ER - TY - JOUR A1 - Kammer, Stefan A1 - Starke, Ines A1 - Pietrucha, Andreas A1 - Kelling, Alexandra A1 - Mickler, Wulfhard A1 - Schilde, Uwe A1 - Dosche, Carsten A1 - Kleinpeter, Erich A1 - Holdt, Hans-Jürgen T1 - 1,12-Diazaperylene and 2,11-dialkylated-1,12-diazaperylene iridium(III) complexes [Ir((CN)-N-boolean AND)(2)((NN)-N-boolean AND)]PF6: new supramolecular assemblies JF - Dalton transactions : a journal of inorganic chemistry, including bioinorganic, organometallic, and solid-state chemistry N2 - A series of new monocationic iridium(III) complexes [Ir((CN)-N-boolean AND)(2)((NN)-N-boolean AND)]PF6 with "large-surface" alpha,alpha'-diimin ligands (NN)-N-boolean AND (dap = 1,12-diazaperylene, dmedap = 2,11-dimethyl-1,12-diazaperylene, dipdap = 2,11-diisopropyl-1,12-diazaperylene) and different cyclometalating ligands (CN)-N-boolean AND (piq = 1-phenylisoquinoline, bzq = benzo[h]quinoline, ppz = 1-phenylpyrazole, thpy = 2-(2-thienyl)pyridine, ppy = 2-phenylpyridine, meppy = 2-(4-methylphenyl)pyridine, dfppy = 2-(2,4-difluorophenyl)pyridine) were synthesized. The solid structures of the complexes [Ir(piq)(2)(dap)]PF6, [Ir(bzq)(2)(dap)]PF6, [Ir(ppy)(2)(dipdap)]PF6, [Ir(piq)(2)(dmedap)]PF6, [Ir(ppy)(2)(dap)]PF6 and [Ir(ppz)(2)(dap)]PF6 are reported. In [Ir(piq)(2)(dap)]PF6, the dap ligand and one of the piq ligands of each cationic complex are involved in pi-pi stacking interactions forming supramolecular channels running along the crystallographic c axis. In the crystalline [Ir(bzq)(2)(dap)]PF6 pi-pi stacking interactions between the metal complexes lead to the formation of a 2D layer structure. In addition, CH-pi interactions were found in all compounds, which are what stabilizes the solid structure. In particular, a significant number of them were found in [Ir(piq)(2)(dap)]PF6 and [Ir(bzq)(2)(dap)]PF6. The crystal structures of [Ir(ppy)(2)(dipdap)]PF6 and [Ir(ppy)(2)(dmedap)]PF6 are also presented, being the first examples of bis-cyclometalated iridium(III) complexes with phenanthroline-type alpha,alpha'-diimin ligands bearing bulky alkyl groups in the neighbourhood of the N-donor atoms. These ligands implicate a distorted octahedral coordination geometry that in turn destabilized the Ir-N-N boolean AND N bonds. The new iridium (III) complexes are not luminescent. All compounds show an electrochemically irreversible anodic peak between 1.15 and 1.58 V, which is influenced by the different cyclometalated ligands. All of the new complexes show two reversible successive one-electron "large-surface" ligand-centred reductions around -0.70 V and -1.30 V. Electrospray ionisation mass spectrometry (ESI-MS) and collision induced decomposition (CID) measurements were used to investigate the stability of the new complexes. Thereby, the stability agreed well with the order of the Ir-N-N boolean AND N bond lengths. Y1 - 2012 U6 - https://doi.org/10.1039/c2dt30412k SN - 1477-9226 VL - 41 IS - 34 SP - 10219 EP - 10227 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Uhlig, Katja A1 - Madaboosi, Narayanan A1 - Schmidt, Stephan A1 - Jäger, Magnus S. A1 - Rose, Jürgen A1 - Duschl, Claus A1 - Volodkin, Dmitry V. T1 - 3d localization and diffusion of proteins in polyelectrolyte multilayers JF - Soft matter N2 - The interaction of diverse biomaterials with surfaces is more crucial than ever for biomedical applications to ensure efficiency and reproducibility. Very interesting surface materials are micrometer-thick polyelectrolyte multilayers. Not only their surface but also the bulk can be loaded with biomaterials like proteins or DNA for various purposes. Therefore, we established a method to analyze the lateral and vertical distribution of fluorescently labelled proteins of various size and charge in polyelectrolyte films composed of poly(L-lysine) and hyaluronic acid by confocal laser scanning microscopy. This approach enables us to measure the diffusion coefficients of the proteins via fluorescence recovery after photobleaching as a function of their vertical position in the film and facilitates the understanding of molecular interactions in the film with a high resolution in both space and time. As a result, we confirm that protein loading in the film is driven by electrostatic interactions - uncharged dextran molecules of 10 and 500 kDa do not diffuse into the film. Proteins of different sizes (3-11 nm) can diffuse relatively fast (D = 2-4 mm(2) s(-1)) independent of their net charge, indicating complex interpolymer interactions. This approach is a new powerful experimental tool to design the polyelectrolyte multilayers for bio-applications by finding a relationship between intermolecular interactions and mobility and availability of biomolecules to biological samples (e.g. cells) or detection units (e.g. biosensors). Y1 - 2012 U6 - https://doi.org/10.1039/c2sm26500a SN - 1744-683X VL - 8 IS - 47 SP - 11786 EP - 11789 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Thompson, W. T. A1 - Kliem, Bernhard A1 - Toeroek, Tibor T1 - 3D reconstruction of a rotating erupting prominence JF - Solar physics : a journal for solar and solar-stellar research and the study of solar terrestrial physics N2 - A bright prominence associated with a coronal mass ejection (CME) was seen erupting from the Sun on 9 April 2008. This prominence was tracked by both the Solar Terrestrial Relations Observatory (STEREO) EUVI and COR1 telescopes, and was seen to rotate about the line of sight as it erupted; therefore, the event has been nicknamed the "Cartwheel CME." The threads of the prominence in the core of the CME quite clearly indicate the structure of a weakly to moderately twisted flux rope throughout the field of view, up to heliocentric heights of 4 solar radii. Although the STEREO separation was 48A degrees, it was possible to match some sharp features in the later part of the eruption as seen in the 304 line in EUVI and in the H alpha-sensitive bandpass of COR1 by both STEREO Ahead and Behind. These features could then be traced out in three-dimensional space, and reprojected into a view in which the eruption is directed toward the observer. The reconstructed view shows that the alignment of the prominence to the vertical axis rotates as it rises up to a leading-edge height of a parts per thousand aEuro parts per thousand 2.5 solar radii, and then remains approximately constant. The alignment at 2.5 solar radii differs by about 115A degrees from the original filament orientation inferred from H alpha and EUV data, and the height profile of the rotation, obtained here for the first time, shows that two thirds of the total rotation are reached within a parts per thousand aEuro parts per thousand 0.5 solar radii above the photosphere. These features are well reproduced by numerical simulations of an unstable moderately twisted flux rope embedded in external flux with a relatively strong shear field component. KW - Corona, active KW - Prominences, active KW - Coronal mass ejections KW - Initiation and propagation KW - Magnetic fields, corona Y1 - 2012 U6 - https://doi.org/10.1007/s11207-011-9868-5 SN - 0038-0938 VL - 276 IS - 1-2 SP - 241 EP - 259 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Gruden, Kristina A1 - Hren, Matjaz A1 - Herman, Ana A1 - Blejec, Andrej A1 - Albrecht, Tanja A1 - Selbig, Joachim A1 - Bauer, Christian G. A1 - Schuchardt, Johannes A1 - Or-Guil, Michal A1 - Zupancic, Klemen A1 - Svajger, Urban A1 - Stabuc, Borut A1 - Ihan, Alojz A1 - Kopitar, Andreja Natasa A1 - Ravnikar, Maja A1 - Knezevic, Miomir A1 - Rozman, Primoz A1 - Jeras, Matjaz T1 - A "Crossomics" study analysing variability of different components in peripheral blood of healthy caucasoid individuals JF - PLoS one N2 - Background: Different immunotherapy approaches for the treatment of cancer and autoimmune diseases are being developed and tested in clinical studies worldwide. Their resulting complex experimental data should be properly evaluated, therefore reliable normal healthy control baseline values are indispensable. Methodology/Principal Findings: To assess intra- and inter-individual variability of various biomarkers, peripheral blood of 16 age and gender equilibrated healthy volunteers was sampled on 3 different days within a period of one month. Complex "crossomics'' analyses of plasma metabolite profiles, antibody concentrations and lymphocyte subset counts as well as whole genome expression profiling in CD4(+)T and NK cells were performed. Some of the observed age, gender and BMI dependences are in agreement with the existing knowledge, like negative correlation between sex hormone levels and age or BMI related increase in lipids and soluble sugars. Thus we can assume that the distribution of all 39.743 analysed markers is well representing the normal Caucasoid population. All lymphocyte subsets, 20% of metabolites and less than 10% of genes, were identified as highly variable in our dataset. Conclusions/Significance: Our study shows that the intra- individual variability was at least two-fold lower compared to the inter-individual one at all investigated levels, showing the importance of personalised medicine approach from yet another perspective. Y1 - 2012 U6 - https://doi.org/10.1371/journal.pone.0028761 SN - 1932-6203 VL - 7 IS - 1 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Isaeva, Olga B. A1 - Kuznetsov, Sergey P. A1 - Sataev, Igor R. T1 - A "saddle-node" bifurcation scenario for birth or destruction of a Smale-Williams solenoid JF - Chaos : an interdisciplinary journal of nonlinear science N2 - Formation or destruction of hyperbolic chaotic attractor under parameter variation is considered with an example represented by Smale-Williams solenoid in stroboscopic Poincare map of two alternately excited non-autonomous van der Pol oscillators. The transition occupies a narrow but finite parameter interval and progresses in such way that periodic orbits constituting a "skeleton" of the attractor undergo saddle-node bifurcation events involving partner orbits from the attractor and from a non-attracting invariant set, which forms together with its stable manifold a basin boundary of the attractor. Y1 - 2012 U6 - https://doi.org/10.1063/1.4766590 SN - 1054-1500 VL - 22 IS - 4 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Costa, A. C. A1 - Bronstert, Axel A1 - de Araujo, Jose Carlos T1 - A channel transmission losses model for different dryland rivers JF - Hydrology and earth system sciences : HESS N2 - Channel transmission losses in drylands take place normally in extensive alluvial channels or streambeds underlain by fractured rocks. They can play an important role in streamflow rates, groundwater recharge, freshwater supply and channel-associated ecosystems. We aim to develop a process-oriented, semi-distributed channel transmission losses model, using process formulations which are suitable for data-scarce dryland environments and applicable to both hydraulically disconnected losing streams and hydraulically connected losing(/gaining) streams. This approach should be able to cover a large variation in climate and hydro-geologic controls, which are typically found in dryland regions of the Earth. Our model was first evaluated for a losing/gaining, hydraulically connected 30 km reach of the Middle Jaguaribe River (MJR), Ceara, Brazil, which drains a catchment area of 20 000 km(2). Secondly, we applied it to a small losing, hydraulically disconnected 1.5 km channel reach in the Walnut Gulch Experimental Watershed (WGEW), Arizona, USA. The model was able to predict reliably the streamflow volume and peak for both case studies without using any parameter calibration procedure. We have shown that the evaluation of the hypotheses on the dominant hydrological processes was fundamental for reducing structural model uncertainties and improving the streamflow prediction. For instance, in the case of the large river reach (MJR), it was shown that both lateral stream-aquifer water fluxes and groundwater flow in the underlying alluvium parallel to the river course are necessary to predict streamflow volume and channel transmission losses, the former process being more relevant than the latter. Regarding model uncertainty, it was shown that the approaches, which were applied for the unsaturated zone processes (highly nonlinear with elaborate numerical solutions), are much more sensitive to parameter variability than those approaches which were used for the saturated zone (mathematically simple water budgeting in aquifer columns, including backwater effects). In case of the MJR-application, we have seen that structural uncertainties due to the limited knowledge of the subsurface saturated system interactions (i.e. groundwater coupling with channel water; possible groundwater flow parallel to the river) were more relevant than those related to the subsurface parameter variability. In case of the WEGW application we have seen that the non-linearity involved in the unsaturated flow processes in disconnected dryland river systems (controlled by the unsaturated zone) generally contain far more model uncertainties than do connected systems controlled by the saturated flow. Therefore, the degree of aridity of a dryland river may be an indicator of potential model uncertainty and subsequent attainable predictability of the system. Y1 - 2012 U6 - https://doi.org/10.5194/hess-16-1111-2012 SN - 1027-5606 VL - 16 IS - 4 SP - 1111 EP - 1135 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Salazar, S. A1 - Frances, F. A1 - Komma, J. A1 - Blume, Theresa A1 - Francke, Till A1 - Bronstert, Axel A1 - Blöschl, Günter T1 - A comparative analysis of the effectiveness of flood management measures based on the concept of "retaining water in the landscape" in different European hydro-climatic regions JF - Natural hazards and earth system sciences N2 - In this paper, we analyse the effectiveness of flood management measures based on the concept known as "retaining water in the landscape". The investigated measures include afforestation, micro-ponds and small-reservoirs. A comparative and model-based methodological approach has been developed and applied for three meso-scale catchments located in different European hydro-climatological regions: Poyo (184 km(2)) in the Spanish Mediterranean, Upper Iller (954 km(2)) in the German Alps and Kamp (621 km(2)) in Northeast-Austria representing the Continental hydro-climate. This comparative analysis has found general similarities in spite of the particular differences among studied areas. In general terms, the flood reduction through the concept of "retaining water in the landscape" depends on the following factors: the storage capacity increase in the catchment resulting from such measures, the characteristics of the rainfall event, the antecedent soil moisture condition and the spatial distribution of such flood management measures in the catchment. In general, our study has shown that, this concept is effective for small and medium events, but almost negligible for the largest and less frequent floods: this holds true for all different hydro-climatic regions, and with different land-use, soils and morphological settings. Y1 - 2012 U6 - https://doi.org/10.5194/nhess-12-3287-2012 SN - 1561-8633 VL - 12 IS - 11 SP - 3287 EP - 3306 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Ziege, Madlen A1 - Hennige-Schulz, Carmen A1 - Muecksch, Frauke A1 - Bierbach, David A1 - Tiedemann, Ralph A1 - Streit, Bruno A1 - Plath, Martin T1 - A comparison of two methods to assess audience-induced changes in male mate choice JF - Current zoology N2 - Multidirectional communicative interactions in social networks can have a profound effect on mate choice behavior. Male Atlantic molly Poecilia mexicana exhibit weaker mating preferences when an audience male is presented. This could be a male strategy to reduce sperm competition risk: interacting more equally with different females may be advantageous because rivals might copy mate choice decisions. In line with this hypothesis, a previous study found males to show a strong audience effect when being observed while exercising mate choice, but not when the rival was presented only before the choice tests. Audience effects on mate choice decisions have been quantified in poeciliid fishes using association preference designs, but it remains unknown if patterns found from measuring association times translate into actual mating behavior. Thus, we created five audience treatments simulating different forms of perceived sperm competition risk and determined focal males' mating preferences by scoring pre-mating (nipping) and mating behavior (gonopodial thrusting). Nipping did not reflect the pattern that was found when association preferences were measured, while a very similar pattern was uncovered in thrusting behavior. The strongest response was observed when the audience could eavesdrop on the focal male's behavior. A reduction in the strength of focal males' preferences was also seen after the rival male had an opportunity to mate with the focal male's preferred mate. In comparison, the reduction of mating preferences in response to an audience was greater when measuring association times than actual mating behavior. While measuring direct sexual interactions between the focal male and both stimulus females not only the male's motivational state is reflected but also females' behavior such as avoidance of male sexual harassment. KW - Communication networks KW - Male mate choice KW - Non-independent mate choice KW - Sexual selection KW - Sperm competition risk KW - Audience effect Y1 - 2012 SN - 1674-5507 VL - 58 IS - 1 SP - 84 EP - 94 PB - Current Zoology CY - Beijing ER - TY - JOUR A1 - Zhang, Zhuo-dong A1 - Wieland, Ralf A1 - Reiche, Matthias A1 - Funk, Roger A1 - Hoffmann, Carsten A1 - Li, Yong A1 - Sommer, Michael T1 - A computational fluid dynamics model for wind simulation: model implementation and experimental validation JF - Journal of Zhejiang University : an international journal ; Science A, Applied physics & engineering : an international applied physics & engineering journal N2 - To provide physically based wind modelling for wind erosion research at regional scale, a 3D computational fluid dynamics (CFD) wind model was developed. The model was programmed in C language based on the Navier-Stokes equations, and it is freely available as open source. Integrated with the spatial analysis and modelling tool (SAMT), the wind model has convenient input preparation and powerful output visualization. To validate the wind model, a series of experiments was conducted in a wind tunnel. A blocking inflow experiment was designed to test the performance of the model on simulation of basic fluid processes. A round obstacle experiment was designed to check if the model could simulate the influences of the obstacle on wind field. Results show that measured and simulated wind fields have high correlations, and the wind model can simulate both the basic processes of the wind and the influences of the obstacle on the wind field. These results show the high reliability of the wind model. A digital elevation model (DEM) of an area (3800 m long and 1700 m wide) in the Xilingele grassland in Inner Mongolia (autonomous region, China) was applied to the model, and a 3D wind field has been successfully generated. The clear implementation of the model and the adequate validation by wind tunnel experiments laid a solid foundation for the prediction and assessment of wind erosion at regional scale. KW - Wind model KW - Computational fluid dynamics (CFD) KW - Wind erosion KW - Wind tunnel experiments KW - Spatial analysis and modelling tool (SAMT) KW - Open source Y1 - 2012 U6 - https://doi.org/10.1631/jzus.A1100231 SN - 1673-565X VL - 13 IS - 4 SP - 274 EP - 283 PB - Zhejiang University Press CY - Hangzou ER - TY - JOUR A1 - Kleinpeter, Erich A1 - Balci, Kubilay A1 - Yapar, G. A1 - Akkaya, S. A1 - Akyuz, S. A1 - Koch, Andreas T1 - A conformational analysis and vibrational spectroscopic investigation on 1,2-bis(o-carboxyphenoxy) ethane molecule N2 - The minima on the potential energy surface of 1,2-bis(o-carboxyphenoxy) ethane (CPE) molecule in its electronic ground state were searched by a molecular dynamics simulation performed with MM2 force field. For each of the found minimum-energy conformers, the corresponding equilibrium geometry, charge distribution, HOMO-LUMO energy gap, force field, vibrational normal modes and associated IR and Raman spectral data were determined by means of the density functional theory (DFT) based electronic structure calculations carried out by using B3LYP method and various Pople- style basis sets. The obtained theoretical data confirmed the significant effects of the intra- and inter-molecular hydrogen bonding interactions on the conformational structure, force field, and group vibrations of the molecule. The same data have also revealed that two of the determined stable conformers, both of which exhibit pseudo-crown structure, are considerably more favorable in energy to the others and accordingly provide the major c ntribution to the experimental spectra of CPE. In the light of the improved vibrational spectral data obtained within the "SQM FF" methodology and "Dual Scale Factors" approach for the monomer and dimer forms of these two conformers, a reliable assignment of the fundamental bands observed in the experimental room-temperature IR and Raman spectra of the molecule was given, and the sensitivities of its group vibratb20s to conformation, substitution and dimerization were discussed. Y1 - 2012 ER - TY - JOUR A1 - Balci, Kubilay A1 - Yapar, G. A1 - Akkaya, Y. A1 - Akyuz, S. A1 - Koch, Andreas A1 - Kleinpeter, Erich T1 - A conformational analysis and vibrational spectroscopic investigation on 1,2-bis(o-carboxyphenoxy) ethane molecule JF - Vibrational spectroscopy : an international journal devoted to applications of infrared and raman spectroscopy N2 - The minima on the potential energy surface of 1,2-bis(o-carboxyphenoxy)ethane (CPE) molecule in its electronic ground state were searched by a molecular dynamics simulation performed with MM2 force field. For each of the found minimum-energy conformers, the corresponding equilibrium geometry, charge distribution, HOMO-LUMO energy gap, force field, vibrational normal modes and associated IR and Raman spectral data were determined by means of the density functional theory (DFT) based electronic structure calculations carried out by using B3LYP method and various Pople-style basis sets. The obtained theoretical data confirmed the significant effects of the intra- and inter-molecular hydrogen bonding interactions on the conformational structure, force field, and group vibrations of the molecule. The same data have also revealed that two of the determined stable conformers, both of which exhibit pseudo-crown structure, are considerably more favorable in energy to the others and accordingly provide the major contribution to the experimental spectra of CPE. In the light of the improved vibrational spectral data obtained within the "SQM FF" methodology and "Dual Scale Factors" approach for the monomer and dimer forms of these two conformers, a reliable assignment of the fundamental bands observed in the experimental room-temperature IR and Raman spectra of the molecule was given, and the sensitivities of its group vibrations to conformation, substitution and dimerization were discussed. KW - Glycol podands KW - Salicylic acid KW - IR and Raman spectra KW - SQM FF KW - Dual Scale Factors Y1 - 2012 U6 - https://doi.org/10.1016/j.vibspec.2011.11.011 SN - 0924-2031 VL - 58 IS - 1-2 SP - 27 EP - 43 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Schewe, Jacob A1 - Levermann, Anders A1 - Cheng, Hai T1 - A critical humidity threshold for monsoon transitions JF - Climate of the past : an interactive open access journal of the European Geosciences Union N2 - Monsoon systems around the world are governed by the so-called moisture-advection feedback. Here we show that, in a minimal conceptual model, this feedback implies a critical threshold with respect to the atmospheric specific humidity q(o) over the ocean adjacent to the monsoon region. If q(o) falls short of this critical value q(o)(c), monsoon rainfall over land cannot be sustained. Such a case could occur if evaporation from the ocean was reduced, e.g. due to low sea surface temperatures. Within the restrictions of the conceptual model, we estimate q(o)(c) from present-day reanalysis data for four major monsoon systems, and demonstrate how this concept can help understand abrupt variations in monsoon strength on orbital timescales as found in proxy records. Y1 - 2012 U6 - https://doi.org/10.5194/cp-8-535-2012 SN - 1814-9324 VL - 8 IS - 2 SP - 535 EP - 544 PB - Copernicus CY - Göttingen ER - TY - JOUR A1 - Ettlinger, Julia A1 - Schenk, Jörg A. A1 - Micheel, Burkhard A1 - Ehrentreich-Förster, Eva A1 - Gajovic-Eichelmann, Nenad T1 - A direct competitive homogeneous immunoassay for progesterone - the Redox Quenching Immunoassay JF - Electroanalysis : an international journal devoted to fundamental and practical aspects of electroanalysis N2 - A direct competitive amperometric immunoassay format for the detection of haptens and proteins was developed. The method is based on the quenching of electroactivity of ferrocenium, which is coupled to the antigen and used as the primary reporter, upon binding to a monoclonal anti-ferrocenium antibody, which is coupled to the detection antibody and used as a secondary reporter. A separation-free progesterone immunoassay with a lower detection limit of 1 ng?mL-1 (3.18 nmol?L-1) in 1?:?2 diluted blood serum was realised by combining two bifunctional conjugates, a ferrocenium-PEG-progesterone tracer and a bioconjugate of one anti-progesterone and one anti-ferrocenium antibody. The immune complex is formed within 30 s upon addition of progesterone, resulting in a total analysis time of 1.5 min. KW - Immunoassay KW - Amperometry KW - Ferrocene KW - Progesterone Y1 - 2012 U6 - https://doi.org/10.1002/elan.201200107 SN - 1040-0397 VL - 24 IS - 7 SP - 1567 EP - 1575 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Struch, Georg T1 - A distributional analysis of recent reform proposals on the german income tax rate JF - Jahrbücher für Nationalökonomie und Statistik = Journal of economics and statistics N2 - The present paper investigates potential fiscal and distributional effects which emerge due to four reform scenarios on the German income tax rate. The analysis is based on a static simulation model for the German tax system using income tax micro-data. The data shows that changing the present progressive tax system to a flat-tax, which was proposed by the FDP in 2010, could reduce the tax revenue by 15 billion Euro. Such a tax regime would increase the unequal distribution and polarisation of net incomes. The IW Koln suggested an alternative tax rate in 2008. This regime would increase unequal distribution and polarisation of disposable incomes to a greater extent than the FDP-tax rate. An implementation of this income tax scale would go along with losses in tax revenue of 18.8 billion Euro. Likewise, the implementation of a 2009 SPD tax rate proposal would reduce tax revenue by 14.8 billion Euro. Although this regime would reduce unequal distribution, the effect on the polarization of disposable incomes is not definitely predictable. In contrast to all the other scenarios, the realisation of the recent SPD tax rate proposal from 2011 could enlarge tax revenue by 4.7 billion Euro. This tax regime would reduce unequal distribution and polarisation of disposable incomes even more than the present tax system. Y1 - 2012 SN - 0021-4027 VL - 232 IS - 5 SP - 567 EP - 588 PB - Lucius & Lucius CY - Stuttgart ER - TY - JOUR A1 - Reich, Sebastian T1 - A Gaussian-mixture ensemble transform filter JF - Quarterly journal of the Royal Meteorological Society N2 - We generalize the popular ensemble Kalman filter to an ensemble transform filter, in which the prior distribution can take the form of a Gaussian mixture or a Gaussian kernel density estimator. The design of the filter is based on a continuous formulation of the Bayesian filter analysis step. We call the new filter algorithm the ensemble Gaussian-mixture filter (EGMF). The EGMF is implemented for three simple test problems (Brownian dynamics in one dimension, Langevin dynamics in two dimensions and the three-dimensional Lorenz-63 model). It is demonstrated that the EGMF is capable of tracking systems with non-Gaussian uni- and multimodal ensemble distributions. KW - data assimilation KW - ensemble Kalman filter KW - nonlinear filtering KW - Gaussian mixtures KW - Gaussian kernel estimators Y1 - 2012 U6 - https://doi.org/10.1002/qj.898 SN - 0035-9009 VL - 138 IS - 662 SP - 222 EP - 233 PB - Wiley-Blackwell CY - Malden ER - TY - JOUR A1 - Khare, Varsha A1 - Ruby, Christian A1 - Sonkaria, Sanjiv T1 - A green and sustainable nanotechnology role of ionic liquids JF - International journal of precision engineering and manufacturing N2 - In the present study, the effects of ionic liquids (ILs) on the stability of nanoparticles in several IL compositions were investigated. In this context, we examined the primary role of ILs in the synthesis of metal/metal oxide nanoparticles and their dispersions extensively. However, the focus of the discussion in this communication centers mainly on the effect of EMIM Ethyl Sulfate on growth and stability of nanoparticles. The dispersion properties of ILs based on their ability to aid the synthesis of uniformly dispersed nanoparticles have been further explored to produce nanoparticles of an effective catalyst useful in water purification, soil remediation and battery applications. Two independent protocols were developed for the synthesis of nanoparticles, namely (a) one pot process via chemical reduction (b) dispersion of the inorganic material in ILs. The protocols are simple, sustainable and environmentally friendly because the processes are conducted in ILs as harmless non-toxic green solvent materials. The catalysts were analyzed by x-ray diffraction, electron microscopy, UV visible spectroscopy and dynamic light scattering as the main methodologies. KW - Nanotechnology KW - Green synthesis KW - Ionic liquid KW - Green rust KW - Gold nanoparticles Y1 - 2012 U6 - https://doi.org/10.1007/s12541-012-0160-x SN - 2234-7593 VL - 13 IS - 7 SP - 1207 EP - 1213 PB - Korean Society of Precision Engineering CY - Seoul ER - TY - JOUR A1 - Fischer, Martin H. T1 - A hierarchical view of grounded, embodied, and situated numerical cognition JF - Cognitive processing : international quarterly of cognitive science N2 - There is much recent interest in the idea that we represent our knowledge together with the sensory and motor features that were activated during its acquisition. This paper reviews the evidence for such "embodiment" in the domain of numerical cognition, a traditional stronghold of abstract theories of knowledge representation. The focus is on spatial-numerical associations, such as the SNARC effect (small numbers are associated with left space, larger numbers with right space). Using empirical evidence from behavioral research, I first describe sensory and motor biases induced by SNARC, thus identifying numbers as embodied concepts. Next, I propose a hierarchical relationship between grounded, embodied, and situated aspects of number knowledge. This hierarchical conceptualization helps to understand the variety of SNARC-related findings and yields testable predictions about numerical cognition. I report several such tests, ranging from cross-cultural comparisons of horizontal and vertical SNARC effects (Shaki and Fischer in J Exp Psychol Hum Percept Perform 38(3): 804-809, 2012) to motor cortical activation studies in adults with left- and right-hand counting preferences (Tschentscher et al. in NeuroImage 59: 3139-3148, 2012). It is concluded that the diagnostic features for each level of the proposed hierarchical knowledge representation, together with the spatial associations of numbers, make the domain of numerical knowledge an ideal testing ground for embodied cognition research. KW - Embodied cognition KW - Grounded cognition KW - Numerical cognition KW - SNARC effect Y1 - 2012 U6 - https://doi.org/10.1007/s10339-012-0477-5 SN - 1612-4782 VL - 13 SP - S161 EP - S164 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Batsios, Petros A1 - Peter, Tatjana A1 - Baumann, Otto A1 - Stick, Reimer A1 - Meyer, Irene A1 - Gräf, Ralph T1 - A lamin in lower eukaryotes? JF - Nucleus N2 - Lamins are the major components of the nuclear lamina and serve not only as a mechanical support, but are also involved in chromatin organization, epigenetic regulation, transcription and mitotic events. Despite these universal tasks, lamins have so far been found only in metazoans. Yet, recently we have identified Dictyostelium NE81 as the first lamin-like protein in a lower eukaryote. Based on the current knowledge, we draw a model for nuclear envelope organization in Dictyostelium in this Extra View and we review the experimental data that justified this classification. Furthermore we provide unpublished data underscoring the requirement of posttranslational CaaX-box processing for proper protein localization at the nuclear envelope. Sequence comparison of NE81 sequences from four Dictyostelia with bona fide lamins illustrates the evolutional relationship between these proteins. Under certain conditions these usually unicellular social amoebae congregate to form a multicellular body. We propose that the evolution of the lamin-like NE81 went along with the invention of multicellularity. KW - dictyostelium KW - lamin KW - intermediate filament KW - centrosome KW - nucleus Y1 - 2012 U6 - https://doi.org/10.4161/nucl.20149 SN - 1949-1034 VL - 3 IS - 3 SP - 237 EP - 243 PB - Landes Bioscience CY - Austin ER - TY - JOUR A1 - Girbig, Dorothee A1 - Selbig, Joachim A1 - Grimbs, Sergio T1 - A MATLAB toolbox for structural kinetic modeling JF - Bioinformatics N2 - Structural kinetic modeling (SKM) enables the analysis of dynamical properties of metabolic networks solely based on topological information and experimental data. Current SKM-based experiments are hampered by the time-intensive process of assigning model parameters and choosing appropriate sampling intervals for MonteCarlo experiments. We introduce a toolbox for the automatic and efficient construction and evaluation of structural kinetic models (SK models). Quantitative and qualitative analyses of network stability properties are performed in an automated manner. We illustrate the model building and analysis process in detailed example scripts that provide toolbox implementations of previously published literature models. Y1 - 2012 U6 - https://doi.org/10.1093/bioinformatics/bts473 SN - 1367-4803 VL - 28 IS - 19 SP - 2546 EP - 2547 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Fürst, Johannes J. A1 - Levermann, Anders T1 - A minimal model for wind- and mixing-driven overturning threshold behavior for both driving mechanisms JF - Climate dynamics : observational, theoretical and computational research on the climate system N2 - We present a minimal conceptual model for the Atlantic meridional overturning circulation which incorporates the advection of salinity and the basic dynamics of the oceanic pycnocline. Four tracer transport processes following Gnanadesikan in Science 283(5410):2077-2079, (1999) allow for a dynamical adjustment of the oceanic pycnocline which defines the vertical extent of a mid-latitudinal box. At the same time the model captures the salt-advection feedback (Stommel in Tellus 13(2):224-230, (1961)). Due to its simplicity the model can be solved analytically in the purely wind- and purely mixing-driven cases. We find the possibility of abrupt transition in response to surface freshwater forcing in both cases even though the circulations are very different in physics and geometry. This analytical approach also provides expressions for the critical freshwater input marking the change in the dynamics of the system. Our analysis shows that including the pycnocline dynamics in a salt-advection model causes a decrease in the freshwater sensitivity of its northern sinking up to a threshold at which the circulation breaks down. Compared to previous studies the model is restricted to the essential ingredients. Still, it exhibits a rich behavior which reaches beyond the scope of this study and might be used as a paradigm for the qualitative behaviour of the Atlantic overturning in the discussion of driving mechanisms. KW - Meridional overturning circulation KW - Northern sinking KW - Critical freshwater threshold KW - Overturning sensitivity KW - Conceptual model KW - Stability KW - Atlantic meridional overturning circulation KW - Pycnocline depth KW - Driving mechanism Y1 - 2012 U6 - https://doi.org/10.1007/s00382-011-1003-7 SN - 0930-7575 VL - 38 IS - 1-2 SP - 239 EP - 260 PB - Springer CY - New York ER - TY - JOUR A1 - Ette, Ottmar A1 - Müller, Gesine T1 - A modo de introducción Y1 - 2012 SN - 978-8-48-489670-8 ER - TY - JOUR A1 - Broeker, Patrick A1 - Luecke, Klaus A1 - Perpeet, Markus A1 - Gronewold, Thomas M. A. T1 - A nanostructured SAW chip-based biosensor detecting cancer cells JF - SENSORS AND ACTUATORS B-CHEMICAL N2 - A nanostructured chip surface was fabricated enabling binding via spaced antibodies specifically targeting surface proteins of cancer cells and detection of extremely low numbers of circulating tumor cells (CTC) without labeling using a sam (R) 5 biosensor. The antibody surfaces mostly were generated by self assembly of antibodies to gold nanospots on the sensitive SiO2-surface of a sam (R) 5 chip. Compared with a complete gold surface, only 40% of the amount of antibodies was bound to the nanospot surface, but structured such that 15-fold higher sensitivity to vital cancer cells was achieved. Human cancer cell lines JEG-3 (lmphoblastic leukemia) and MOLT-17 (placental choriocarcinoma) from cell cultures were successfully detected. The sensor showed significant responses on less than 10 cells injected in a single run. The extreme increase in sensitivity and its simple regeneration emphasizes the usefulness of its introduction in biomedical applications. (C) 2011 Elsevier B.V. All rights reserved. KW - Nanospots KW - Nanostructured surfaces KW - SAW sensor KW - Cell detection KW - Cancer cells KW - sam (R) 5 Y1 - 2012 U6 - https://doi.org/10.1016/j.snb.2011.11.022 SN - 0925-4005 VL - 165 IS - 1 SP - 1 EP - 6 PB - ELSEVIER SCIENCE SA CY - LAUSANNE ER - TY - JOUR A1 - Haase, A. A1 - Mantion, A. A1 - Graf, P. A1 - Plendl, J. A1 - Thünemann, Andreas F. A1 - Meier, Wolfgang P. A1 - Taubert, Andreas A1 - Luch, A. T1 - A novel type of silver nanoparticles and their advantages in toxicity testing in cell culture systems JF - Archives of toxicology : official journal of EUROTOX N2 - Silver nanoparticles (SNPs) are among the most commercialized nanoparticles worldwide. Often SNP are used because of their antibacterial properties. Besides that they possess unique optic and catalytic features, making them highly interesting for the creation of novel and advanced functional materials. Despite its widespread use only little data exist in terms of possible adverse effects of SNP on human health. Conventional synthesis routes usually yield products of varying quality and property. It thus may become puzzling to compare biological data from different studies due to the great variety in sizes, coatings or shapes of the particles applied. Here, we applied a novel synthesis approach to obtain SNP of well-defined colloidal and structural properties. Being stabilized by a covalently linked small peptide, these particles are nicely homogenous, with narrow size distribution, and form monodisperse suspensions in aqueous solutions. We applied these peptide-coated SNP in two different sizes of 20 or 40 nm (Ag20Pep and Ag40Pep) and analyzed responses of THP-1-derived human macrophages while being exposed against these particles. Gold nanoparticles of similar size and coating (Au20Pep) were used for comparison. The cytotoxicity of particles was assessed by WST-1 and LDH assays, and the uptake into the cells was confirmed via transmission electron microscopy. In summary, our data demonstrate that this novel type of SNP is well suited to serve as model system for nanoparticles to be tested in toxicological studies in vitro. KW - Silver nanoparticles KW - Peptide coating KW - Nanotoxicity Y1 - 2012 U6 - https://doi.org/10.1007/s00204-012-0836-0 SN - 0340-5761 VL - 86 IS - 7 SP - 1089 EP - 1098 PB - Springer CY - Heidelberg ER - TY - JOUR A1 - Kliem, Bernhard A1 - Török, Tibor A1 - Thompson, William T. T1 - A parametric study of erupting flux rope rotation modeling the "Cartwheel CME" on 9 April 2008 JF - Solar physics : a journal for solar and solar-stellar research and the study of solar terrestrial physics N2 - The rotation of erupting filaments in the solar corona is addressed through a parametric simulation study of unstable, rotating flux ropes in bipolar force-free initial equilibrium. The Lorentz force due to the external shear-field component and the relaxation of tension in the twisted field are the major contributors to the rotation in this model, while reconnection with the ambient field is of minor importance, due to the field's simple structure. In the low-beta corona, the rotation is not guided by the changing orientation of the vertical field component's polarity inversion line with height. The model yields strong initial rotations which saturate in the corona and differ qualitatively from the profile of rotation vs. height obtained in a recent simulation of an eruption without preexisting flux rope. Both major mechanisms writhe the flux rope axis, converting part of the initial twist helicity, and produce rotation profiles which, to a large part, are very similar within a range of shear-twist combinations. A difference lies in the tendency of twist-driven rotation to saturate at lower heights than shear-driven rotation. For parameters characteristic of the source regions of erupting filaments and coronal mass ejections, the shear field is found to be the dominant origin of rotations in the corona and to be required if the rotation reaches angles of order 90 degrees and higher; it dominates even if the twist exceeds the threshold of the helical kink instability. The contributions by shear and twist to the total rotation can be disentangled in the analysis of observations if the rotation and rise profiles are simultaneously compared with model calculations. The resulting twist estimate allows one to judge whether the helical kink instability occurred. This is demonstrated for the erupting prominence in the "Cartwheel CME" on 9 April 2008, which has shown a rotation of a parts per thousand aEuro parts per thousand 115(a similar to) up to a height of 1.5 R (aS (TM)) above the photosphere. Out of a range of initial equilibria which include strongly kink-unstable (twist I broken vertical bar=5 pi), weakly kink-unstable (I broken vertical bar=3.5 pi), and kink-stable (I broken vertical bar=2.5 pi) configurations, only the evolution of the weakly kink-unstable flux rope matches the observations in their entirety. KW - Corona, active KW - Prominences, dynamics KW - Coronal mass ejections, initiation and propagation KW - Magnetic fields, corona KW - Magnetohydrodynamics Y1 - 2012 U6 - https://doi.org/10.1007/s11207-012-9990-z SN - 0038-0938 VL - 281 IS - 1 SP - 137 EP - 166 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Blüthgen, Nico A1 - Dormann, Carsten F. A1 - Prati, Daniel A1 - Klaus, Valentin H. A1 - Kleinebecker, Till A1 - Hoelzel, Norbert A1 - Alt, Fabian A1 - Boch, Steffen A1 - Gockel, Sonja A1 - Hemp, Andreas A1 - Müller, Jörg A1 - Nieschulze, Jens A1 - Renner, Swen C. A1 - Schöning, Ingo A1 - Schumacher, Uta A1 - Socher, Stephanie A. A1 - Wells, Konstans A1 - Birkhofer, Klaus A1 - Buscot, Francois A1 - Oelmann, Yvonne A1 - Rothenwöhrer, Christoph A1 - Scherber, Christoph A1 - Tscharntke, Teja A1 - Weiner, Christiane N. A1 - Fischer, Markus A1 - Kalko, Elisabeth K. V. A1 - Linsenmair, Karl Eduard A1 - Schulze, Ernst-Detlef A1 - Weisser, Wolfgang W. T1 - A quantitative index of land-use intensity in grasslands integrating mowing, grazing and fertilization JF - Basic and applied ecology : Journal of the Gesellschaft für Ökologie N2 - Land use is increasingly recognized as a major driver of biodiversity and ecosystem functioning in many current research projects. In grasslands, land use is often classified by categorical descriptors such as pastures versus meadows or fertilized versus unfertilized sites. However, to account for the quantitative variation of multiple land-use types in heterogeneous landscapes, a quantitative, continuous index of land-use intensity (LUI) is desirable. Here we define such a compound, additive LUI index for managed grasslands including meadows and pastures. The LUI index summarizes the standardized intensity of three components of land use, namely fertilization, mowing, and livestock grazing at each site. We examined the performance of the LUI index to predict selected response variables on up to 150 grassland sites in the Biodiversity Exploratories in three regions in Germany(Alb, Hainich, Schorlheide). We tested the average Ellenberg nitrogen indicator values of the plant community, nitrogen and phosphorus concentration in the aboveground plant biomass, plant-available phosphorus concentration in the top soil, and soil C/N ratio, and the first principle component of these five response variables. The LUI index significantly predicted the principal component of all five response variables, as well as some of the individual responses. Moreover, vascular plant diversity decreased significantly with LUI in two regions (Alb and Hainich). Inter-annual changes in management practice were pronounced from 2006 to 2008, particularly due to variation in grazing intensity. This rendered the selection of the appropriate reference year(s) an important decision for analyses of land-use effects, whereas details in the standardization of the index were of minor importance. We also tested several alternative calculations of a LUI index, but all are strongly linearly correlated to the proposed index. The proposed LUI index reduces the complexity of agricultural practices to a single dimension and may serve as a baseline to test how different groups of organisms and processes respond to land use. In combination with more detailed analyses, this index may help to unravel whether and how land-use intensities, associated disturbance levels or other local or regional influences drive ecological processes. KW - Agro-ecosystems KW - Biodiversity exploratories KW - Grassland management KW - Land-use impacts KW - Livestock density KW - Meadows KW - Nitrogen KW - Pastures Y1 - 2012 U6 - https://doi.org/10.1016/j.baae.2012.04.001 SN - 1439-1791 VL - 13 IS - 3 SP - 207 EP - 220 PB - Elsevier CY - Jena ER - TY - JOUR A1 - Evans, C. J. A1 - Hainich, Rainer A1 - Oskinova, Lida A1 - Gallagher, J. S. A1 - Chu, Y.-H. A1 - Gruendl, R. A. A1 - Hamann, Wolf-Rainer A1 - Henault-Brunet, V. A1 - Todt, Helge Tobias T1 - A rare early-type star revealed in the wing of the small megellanic cloud JF - The astrophysical journal : an international review of spectroscopy and astronomical physics N2 - Sk 183 is the visually brightest star in the N90 nebula, a young star-forming region in the Wing of the Small Magellanic Cloud (SMC). We present new optical spectroscopy from the Very Large Telescope which reveals Sk 183 to be one of the most massive O-type stars in the SMC. Classified as an O3-type dwarf on the basis of its nitrogen spectrum, the star also displays broadened He I absorption, which suggests a later type. We propose that Sk 183 has a composite spectrum and that it is similar to another star in the SMC, MPG 324. This brings the number of rare O2- and O3-type stars known in the whole of the SMC to a mere four. We estimate physical parameters for Sk 183 from analysis of its spectrum. For a single-star model, we estimate an effective temperature of 46 +/- 2 kK, a low mass-loss rate of similar to 10(-7) M-circle dot yr(-1), and a spectroscopic mass of 46(-8)(+ 9) M-circle dot (for an adopted distance modulus of 18.7 mag to the young population in the SMC Wing). An illustrative binary model requires a slightly hotter temperature (similar to 47.5 kK) for the primary component. In either scenario, Sk 183 is the earliest-type star known in N90 and will therefore be the dominant source of hydrogen-ionizing photons. This suggests Sk 183 is the primary influence on the star formation along the inner edge of the nebula. KW - open clusters and associations: individual (NGC 602) KW - stars: early-type KW - stars: fundamental parameters KW - stars: individual (Sanduleak 183) Y1 - 2012 U6 - https://doi.org/10.1088/0004-637X/753/2/173 SN - 0004-637X VL - 753 IS - 2 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Nehring, Benjamin A1 - Zessin, Hans T1 - A representation of the moment measures of the general ideal Boe gas JF - Mathematische Nachrichten N2 - We reconsider the fundamental work of Fichtner 2 and exhibit the permanental structure of the ideal Bose gas again, using a new approach which combines a characterization of infinitely divisible random measures (due to Kerstan, Kummer and Matthes 4, 6 and Mecke 9, 10) with a decomposition of the moment measures into its factorial measures due to Krickeberg 5. To be more precise, we exhibit the moment measures of all orders of the general ideal Bose gas in terms of certain loop integrals. This representation can be considered as a point process analogue of the old idea of Symanzik 15 that local times and self-crossings of the Brownian motion can be used as a tool in quantum field theory. Behind the notion of a general ideal Bose gas there is a class of infinitely divisible point processes of all orders with a Levy-measure belonging to some large class of measures containing that of the classical ideal Bose gas considered by Fichtner. It is well-known that the calculation of moments of higher order of point processes is notoriously complicated. See for instance Krickebergs calculations for the Poisson or the Cox process in 5. Relations to the work of Shirai, Takahashi 12 and Soshnikov 14 on permanental and determinantal processes are outlined. KW - Infinitely divisible point processes KW - integration by parts formula KW - random KMM-measure KW - permanental and determinantal point processes (MSC 2010) 35K55 KW - 35K65 Y1 - 2012 U6 - https://doi.org/10.1002/mana.201000111 SN - 0025-584X VL - 285 IS - 7 SP - 878 EP - 888 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Hammer, Conny A1 - Beyreuther, Moritz A1 - Ohrnberger, Matthias T1 - A seismic-event spotting system for volcano fast-response systems JF - Bulletin of the Seismological Society of America N2 - Volcanic eruptions are often preceded by seismic activity that can be used to quantify the volcanic activity. In order to allow consistent inference of the volcanic activity state from the observed seismicity patterns, objective and time-invariant classification results achievable by automatic systems should be preferred. Most automatic classification approaches need a large preclassified data set for training the system. However, in case of a volcanic crisis, we are often confronted with a lack of training data due to insufficient prior observations. In the worst case (e. g., volcanic crisis related reconfiguration of stations), there are even no prior observations available. Finally, due to the imminent crisis there might be no time for the time-consuming process of preparing a training data set. For this reason, we have developed a novel seismic-event spotting technique in order to be less dependent on previously acquired data bases and classification schemes. We are using a learning-while-recording approach based on a minimum number of reference waveforms, thus allowing for the build-up of a classification scheme as early as interesting events have been identified. First, short-term wave-field parameters (here, polarization and spectral attributes) are extracted from a continuous seismic data stream. The sequence of multidimensional feature vectors is then used to identify a fixed number of clusters in the feature space. Based on this general description of the overall wave field by a mixture of multivariate Gaussians, we are able to learn particular event classifiers (here, hidden Markov models) from a single waveform example. To show the capabilities of this new approach we apply the algorithm to a data set recorded at Soufriere Hills volcano, Montserrat. Supported by very high classification rates, we conclude that the suggested approach provides a valuable tool for volcano monitoring systems. Y1 - 2012 U6 - https://doi.org/10.1785/0120110167 SN - 0037-1106 VL - 102 IS - 3 SP - 948 EP - 960 PB - Seismological Society of America CY - Albany ER - TY - JOUR A1 - Kunnus, Kristjan A1 - Rajkovic, Ivan A1 - Schreck, Simon A1 - Quevedo, Wilson A1 - Eckert, Sebastian A1 - Beye, Martin A1 - Suljoti, Edlira A1 - Weniger, Christian A1 - Kalus, Christian A1 - Gruebel, Sebastian A1 - Scholz, Mirko A1 - Nordlund, Dennis A1 - Zhang, Wenkai A1 - Hartsock, Robert W. A1 - Gaffney, Kelly J. A1 - Schlotter, William F. A1 - Turner, Joshua J. A1 - Kennedy, Brian A1 - Hennies, Franz A1 - Techert, Simone A1 - Wernet, Philippe A1 - Föhlisch, Alexander T1 - A setup for resonant inelastic soft x-ray scattering on liquids at free electron laser light sources JF - Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques N2 - We present a flexible and compact experimental setup that combines an in vacuum liquid jet with an x-ray emission spectrometer to enable static and femtosecond time-resolved resonant inelastic soft x-ray scattering (RIXS) measurements from liquids at free electron laser (FEL) light sources. We demonstrate the feasibility of this type of experiments with the measurements performed at the Linac Coherent Light Source FEL facility. At the FEL we observed changes in the RIXS spectra at high peak fluences which currently sets a limit to maximum attainable count rate at FELs. The setup presented here opens up new possibilities to study the structure and dynamics in liquids. Y1 - 2012 U6 - https://doi.org/10.1063/1.4772685 SN - 0034-6748 VL - 83 IS - 12 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Sereshki, L. E. A1 - Lomholt, M. A. A1 - Metzler, Ralf T1 - A solution to the subdiffusion-efficiency paradox inactive states enhance reaction efficiency at subdiffusion conditions in living cells JF - epl : a letters journal exploring the frontiers of physics N2 - Macromolecular crowding in living biological cells effects subdiffusion of larger biomolecules such as proteins and enzymes. Mimicking this subdiffusion in terms of random walks on a critical percolation cluster, we here present a case study of EcoRV restriction enzymes involved in vital cellular defence. We show that due to its so far elusive propensity to an inactive state the enzyme avoids non-specific binding and remains well-distributed in the bulk cytoplasm of the cell. Despite the reduced volume exploration capability of subdiffusion processes, this mechanism guarantees a high efficiency of the enzyme. By variation of the non-specific binding constant and the bond occupation probability on the percolation network, we demonstrate that reduced nonspecific binding are beneficial for efficient subdiffusive enzyme activity even in relatively small bacteria cells. Our results corroborate a more local picture of cellular regulation. Y1 - 2012 U6 - https://doi.org/10.1209/0295-5075/97/20008 SN - 0295-5075 VL - 97 IS - 2 PB - EDP Sciences CY - Mulhouse ER - TY - JOUR A1 - Schewe, Jacob A1 - Levermann, Anders T1 - A statistically predictive model for future monsoon failure in India JF - Environmental research letters N2 - Indian monsoon rainfall is vital for a large share of the world's population. Both reliably projecting India's future precipitation and unraveling abrupt cessations of monsoon rainfall found in paleorecords require improved understanding of its stability properties. While details of monsoon circulations and the associated rainfall are complex, full-season failure is dominated by large-scale positive feedbacks within the region. Here we find that in a comprehensive climate model, monsoon failure is possible but very rare under pre-industrial conditions, while under future warming it becomes much more frequent. We identify the fundamental intraseasonal feedbacks that are responsible for monsoon failure in the climate model, relate these to observational data, and build a statistically predictive model for such failure. This model provides a simple dynamical explanation for future changes in the frequency distribution of seasonal mean all-Indian rainfall. Forced only by global mean temperature and the strength of the Pacific Walker circulation in spring, it reproduces the trend as well as the multidecadal variability in the mean and skewness of the distribution, as found in the climate model. The approach offers an alternative perspective on large-scale monsoon variability as the result of internal instabilities modulated by pre-seasonal ambient climate conditions. KW - monsoon failure KW - climate change KW - coupled climate model KW - stochastic model KW - non-linear dynamics Y1 - 2012 U6 - https://doi.org/10.1088/1748-9326/7/4/044023 SN - 1748-9326 VL - 7 IS - 4 PB - IOP Publ. Ltd. CY - Bristol ER - TY - JOUR A1 - Amselem, Gabriel A1 - Theves, Matthias A1 - Bae, Albert J. A1 - Bodenschatz, Eberhard A1 - Beta, Carsten T1 - A stochastic description of dictyostelium chemotaxis JF - PLoS one N2 - Chemotaxis, the directed motion of a cell toward a chemical source, plays a key role in many essential biological processes. Here, we derive a statistical model that quantitatively describes the chemotactic motion of eukaryotic cells in a chemical gradient. Our model is based on observations of the chemotactic motion of the social ameba Dictyostelium discoideum, a model organism for eukaryotic chemotaxis. A large number of cell trajectories in stationary, linear chemoattractant gradients is measured, using microfluidic tools in combination with automated cell tracking. We describe the directional motion as the interplay between deterministic and stochastic contributions based on a Langevin equation. The functional form of this equation is directly extracted from experimental data by angle-resolved conditional averages. It contains quadratic deterministic damping and multiplicative noise. In the presence of an external gradient, the deterministic part shows a clear angular dependence that takes the form of a force pointing in gradient direction. With increasing gradient steepness, this force passes through a maximum that coincides with maxima in both speed and directionality of the cells. The stochastic part, on the other hand, does not depend on the orientation of the directional cue and remains independent of the gradient magnitude. Numerical simulations of our probabilistic model yield quantitative agreement with the experimental distribution functions. Thus our model captures well the dynamics of chemotactic cells and can serve to quantify differences and similarities of different chemotactic eukaryotes. Finally, on the basis of our model, we can characterize the heterogeneity within a population of chemotactic cells. Y1 - 2012 U6 - https://doi.org/10.1371/journal.pone.0037213 SN - 1932-6203 VL - 7 IS - 5 PB - PLoS CY - San Fransisco ER - TY - JOUR A1 - Sauer, Patrick A1 - Glombitza, Clemens A1 - Kallmeyer, Jens T1 - A system for incubations at high gas partial pressure JF - Frontiers in microbiology N2 - High-pressure is a key feature of deep subsurface environments. High partial pressure of dissolved gasses plays an important role in microbial metabolism, because thermodynamic feasibility of many reactions depends on the concentration of reactants. For gases, this is controlled by their partial pressure, which can exceed 1 MPa at in situ conditions. Therefore, high hydrostatic pressure alone is not sufficient to recreate true deep subsurface in situ conditions, but the partial pressure of dissolved gasses has to be controlled as well. We developed an incubation system that allows for incubations at hydrostatic pressure up to 60 MPa, temperatures up to 120 degrees C, and at high gas partial pressure. The composition and partial pressure of gasses can be manipulated during the experiment. To keep costs low, the system is mainly made from off-the-shelf components with only very few custommade parts. A flexible and inert PVDF (polyvinylidene fluoride) incubator sleeve, which is almost impermeable for gases, holds the sample and separates it from the pressure fluid. The flexibility of the incubator sleeve allows for sub-sampling of the medium without loss of pressure. Experiments can be run in both static and flow-through mode. The incubation system described here is usable for versatile purposes, not only the incubation of microorganisms and determination of growth rates, but also for chemical degradation or extraction experiments under high gas saturation, e.g., fluid-gas-rock-interactions in relation to carbon dioxide sequestration. As an application of the system we extracted organic compounds from sub-bituminous coal using H2O as well as a H2O-CO2 mixture at elevated temperature (90 degrees C) and pressure (5 MPa). Subsamples were taken at different time points during the incubation and analyzed by ion chromatography. Furthermore we demonstrated the applicability of the system for studies of microbial activity, using samples from the Isis mud volcano. We could detect an increase in sulfate reduction rate upon the addition of methane to the sample. KW - high-pressure incubation system KW - gas partial pressure KW - sub-sampling KW - carbon dioxide KW - low molecular weight organic acids Y1 - 2012 U6 - https://doi.org/10.3389/fmicb.2012.00025 SN - 1664-302X VL - 3 PB - Frontiers Research Foundation CY - Lausanne ER - TY - JOUR A1 - Xie, Zai-Lai A1 - Xu, Hai-Bing A1 - Gessner, Andre A1 - Kumke, Michael Uwe A1 - Priebe, Magdalena A1 - Fromm, Katharina M. A1 - Taubert, Andreas T1 - A transparent, flexible, ion conductive, and luminescent PMMA ionogel based on a Pt/Eu bimetallic complex and the ionic liquid [Bmim][N(Tf)(2)] JF - Journal of materials chemistry N2 - Transparent, ion-conducting, luminescent, and flexible ionogels based on the room temperature ionic liquid (IL) 1-butyl-3-methylimidazolium bis(trifluoromethane sulfonyl) imide [Bmim][N(Tf)(2)], a PtEu2 chromophore, and poly(methylmethacrylate) (PMMA) have been prepared. The thermal stability of the PMMA significantly increases with IL incorporation. In particular, the onset weight loss observed at ca. 229 degrees C for pure PMMA increases to 305 degrees C with IL addition. The ionogel has a high ionic conductivity of 10(-3) S cm(-1) at 373 K and exhibits a strong emission in the red with a long average luminescence decay time of tau = 890 mu s. The resulting material is a new type of soft hybrid material featuring useful thermal, optical, and ion transport properties. Y1 - 2012 U6 - https://doi.org/10.1039/c2jm15862k SN - 0959-9428 VL - 22 IS - 16 SP - 8110 EP - 8116 PB - Royal Society of Chemistry CY - Cambridge ER -