TY  - JOUR
A1  - Ghosh, Surya K.
A1  - Cherstvy, Andrey G.
A1  - Petrov, Eugene P.
A1  - Metzler, Ralf
T1  - Interactions of rod-like particles on responsive elastic sheets
JF  - Soft matter
N2  - What are the physical laws of the mutual interactions of objects bound to cell membranes, such as various membrane proteins or elongated virus particles? To rationalise this, we here investigate by extensive computer simulations mutual interactions of rod-like particles adsorbed on the surface of responsive elastic two-dimensional sheets. Specifically, we quantify sheet deformations as a response to adhesion of such filamentous particles. We demonstrate that tip-to-tip contacts of rods are favoured for relatively soft sheets, while side-by-side contacts are preferred for stiffer elastic substrates. These attractive orientation-dependent substrate-mediated interactions between the rod-like particles on responsive sheets can drive their aggregation and self-assembly. The optimal orientation of the membrane-bound rods is established via responding to the elastic energy profiles created around the particles. We unveil the phase diagramme of attractive–repulsive rod–rod interactions in the plane of their separation and mutual orientation. Applications of our results to other systems featuring membrane-associated particles are also discussed.
Y1  - 2016
U6  - https://doi.org/10.1039/C6SM01522K
SN  - 1744-6848
SN  - 1744-683X
PB  - RSC
CY  - London
ER  - 
TY  - JOUR
A1  - Ghosh, Surya K.
A1  - Cherstvy, Andrey G.
A1  - Petrov, Eugene P.
A1  - Metzler, Ralf
T1  - Interactions of rod-like particles on responsive elastic sheets
JF  - Soft matter
N2  - What are the physical laws of the mutual interactions of objects bound to cell membranes, such as various membrane proteins or elongated virus particles? To rationalise this, we here investigate by extensive computer simulations mutual interactions of rod-like particles adsorbed on the surface of responsive elastic two-dimensional sheets. Specifically, we quantify sheet deformations as a response to adhesion of such filamentous particles. We demonstrate that tip-to-tip contacts of rods are favoured for relatively soft sheets, while side-by-side contacts are preferred for stiffer elastic substrates. These attractive orientation-dependent substrate-mediated interactions between the rod-like particles on responsive sheets can drive their aggregation and self-assembly. The optimal orientation of the membrane-bound rods is established via responding to the elastic energy profiles created around the particles. We unveil the phase diagramme of attractive-repulsive rod-rod interactions in the plane of their separation and mutual orientation. Applications of our results to other systems featuring membrane-associated particles are also discussed.
Y1  - 2016
U6  - https://doi.org/10.1039/c6sm01522k
SN  - 1744-683X
SN  - 1744-6848
VL  - 12
SP  - 7908
EP  - 7919
PB  - Royal Society of Chemistry
CY  - Cambridge
ER  -