TY - GEN A1 - Zech, Philipp A. A1 - Rapp, Michael Armin A1 - Heinzel, Stephan A1 - Wolfarth, Bernd A1 - Lawrence, Jimmy B. A1 - Heissel, Andreas T1 - Does Exercise Help People Living with HIV Improve Their Quality of Life? A meta-analysis. T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2017 U6 - https://doi.org/10.1249/01.mss.0000518177.22369.2f SN - 0195-9131 SN - 1530-0315 VL - 49 SP - 470 EP - 470 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Wippert, Pia-Maria T1 - Stress and bone health T2 - Psychoneuroendocrinology Y1 - 2019 U6 - https://doi.org/10.1016/j.psyneuen.2019.07.021 SN - 0306-4530 VL - 107 SP - 8 EP - 8 PB - Elsevier CY - Oxford ER - TY - GEN A1 - Völler, Heinz A1 - Bindl, Dominik A1 - Nagels, Klaus A1 - Hofmann, Reiner A1 - Vettorazzi, Eik A1 - Wegscheider, Karl A1 - Fleck, Eckart A1 - Nagel, Eckhard T1 - Remote telemonitoring in chronic heart failure does not reduce healthcare cost but improves quality of life BT - endpoints of the cardiobbeat trail T2 - Journal of the American College of Cardiology N2 - Background: Evidence that home telemonitoring (HTM) for patients with chronic heart failure (CHF) offers clinical benefit over usual care is controversial as is evidence of a health economic advantage. Therefore the CardioBBEAT trial was designed to prospectively assess the health economic impact of a dedicated home monitoring system for patients with CHF based on actual costs directly obtained from patients’ health care providers. Methods: Between January 2010 and June 2013, 621 patients (mean age 63,0 ± 11,5 years, 88 % male) with a confirmed diagnosis of CHF (LVEF ≤ 40 %) were enrolled and randomly assigned to two study groups comprising usual care with and without an interactive bi-directional HTM (Motiva®). The primary endpoint was the Incremental Cost-Effectiveness Ratio (ICER) established by the groups’ difference in total cost and in the combined clinical endpoint “days alive and not in hospital nor inpatient care per potential days in study” within the follow up of 12 months. Secondary outcome measures were total mortality and health related quality of life (SF-36, WHO-5 and KCCQ). Results: In the intention-to-treat analysis, total mortality (HR 0.81; 95% CI 0.45 – 1.45) and days alive and not in hospital (343.3 ± 55.4 vs. 347.2 ± 43.9; p = 0.909) were not significantly different between HTM and usual care. While the resulting primary endpoint ICER was not positive (-181.9; 95% CI −1626.2 ± 1628.9), quality of life assessed by SF-36, WHO-5 and KCCQ as a secondary endpoint was significantly higher in the HTW group at 6 and 12 months of follow-up. Conclusions: The first simultaneous assessment of clinical and economic outcome of HTM in patients with CHF did not demonstrate superior incremental cost effectiveness compared to usual care. On the other hand, quality of life was improved. It remains open whether the tested HTM solution represents a useful innovative approach in the recent health care setting. Y1 - 2017 SN - 0735-1097 SN - 1558-3597 VL - 69 IS - 11 Supplement SP - 672 EP - 672 PB - Elsevier CY - New York ER - TY - GEN A1 - Timme, Sinika T1 - The face of affect and exertion BT - automated facial action analysis to decode the flow of experience during exercise T2 - Journal of sport & exercise psychology Y1 - 2020 SN - 0895-2779 SN - 1543-2904 VL - 42 SP - S3 EP - S3 PB - Human Kinetics Publishers CY - Champaign ER - TY - GEN A1 - Teichler, Hans Joachim ED - Rürup, Reinhard T1 - 1936 : die Olympischen Spiele und der Nationalsozialismus ; eine Dokumentation BT - Neunzehnhundertsechsunddreißig : die Olympischen Spiele und der Nationalsozialismus Y1 - 1996 PB - Verl. Argon CY - Berlin ER - TY - GEN A1 - Teichler, Hans Joachim T1 - Altrock und Diem - zwei vergleichbare Biographien Y1 - 2005 SN - 0933-5315 ER - TY - GEN A1 - Tammen, Harald A1 - Koemhoff, Martin A1 - Mark, Michael A1 - Hocher, Berthold A1 - Delic, Denis A1 - Hess, Rüdiger A1 - von Eynatten, Maximilian A1 - Klein, Thomas T1 - Linagliptin treatment is associated with improved cobalamin (vitamin B-12) storage in mice and potentially in humans T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2018 SN - 0012-186X SN - 1432-0428 VL - 61 SP - S252 EP - S253 PB - Springer CY - New York ER - TY - GEN A1 - Sebold, Miriam Hannah A1 - Nebe, Stephan A1 - Garbusow, Maria A1 - Schad, Daniel A1 - Sommer, Christian A1 - Rapp, Michael Armin A1 - Smolka, Michael N. A1 - Huys, Quentin J. M. A1 - Schlagenhauf, Florian A1 - Heinz, Andreas T1 - Neurobiological correlates of learning and decision-making in alcohol dependence T2 - European psychiatry : the journal of the Association of European Psychiatrists Y1 - 2017 U6 - https://doi.org/10.1016/j.eurpsy.2017.01.084 SN - 0924-9338 SN - 1778-3585 VL - 41 SP - S11 EP - S11 PB - Elsevier CY - Paris ER - TY - GEN A1 - Schwerbel, Kristin A1 - Kamitz, Anne A1 - Jaehnert, Markus A1 - Gottmann, P. A1 - Schumacher, Fabian A1 - Kleuser, Burkhard A1 - Haltenhof, T. A1 - Heyd, F. A1 - Roden, Michael A1 - Chadt, Alexandra A1 - Al-Hasani, Hadi A1 - Jonas, W. A1 - Vogel, Heike A1 - Schürmann, Annette T1 - Two immune-related GTPases prevent from hepatic fat accumulation by inducing autophagy T2 - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) Y1 - 2018 SN - 0012-186X SN - 1432-0428 VL - 61 SP - S259 EP - S259 PB - Springer CY - New York ER - TY - GEN A1 - Schraplau, Anne A1 - Sonnenburg, Dominik A1 - Wochatz, Monique A1 - Engel, Tilman A1 - Schomöller, Anne A1 - Risch, Lucie A1 - Kaplick, Hannes A1 - Mayer, Frank T1 - Characterization of muscle damage and inflammation following repeated maximal eccentric loading of the trunk T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine N2 - Eccentric exercises (ECC) induce reversible muscle damage, delayed-onset muscle soreness and an inflammatory reaction that is often followed by a systemic anti-inflammatory response. Thus, ECC might be beneficial for treatment of metabolic disorders which are frequently accompanied by a low-grade systemic inflammation. However, extent and time course of a systemic immune response after repeated ECC bouts are poorly characterized. PURPOSE: To analyze the (anti-)inflammatory response after repeated ECC loading of the trunk. METHODS: Ten healthy participants (33 ± 6 y; 173 ± 14 cm; 74 ± 16 kg) performed three isokinetic strength measurements of the trunk (concentric (CON), ECC1, ECC2, each 2 wks apart; flexion/extension, velocity 60°/s, 120s MVC). Pre- and 4, 24, 48, 72, 168h post-exercise, muscle soreness (numeric rating scale, NRS) was assessed and blood samples were taken and analyzed [Creatine kinase (CK), C-reactive protein (CRP), Interleukin-6 (IL-6), IL-10, Tumor necrosis factor-α (TNF-α)]. Statistics were done by Friedman‘s test with Dunn‘s post hoc test (α=.05). RESULTS: Mean peak torque was higher during ECC1 (319 ± 142 Nm) than during CON (268 ± 108 Nm; p<.05) and not different between ECC1 and ECC2 (297 ± 126 Nm; p>.05). Markers of muscle damage (peaks post-ECC1: NRS 48h, 4.4±2.9; CK 72h, 14407 ± 19991 U/l) were higher after ECC1 than after CON and ECC2 (p<.05). The responses over 72h (stated as Area under the Curve, AUC) were abolished after ECC2 compared to ECC1 (p<.05) indicating the presence of the repeated bout effect. CRP levels were not changed. IL-6 levels increased 2-fold post-ECC1 (pre: 0.5 ± 0.4 vs. 72h: 1.0 ± 0.8 pg/ml). The IL-6 response was enhanced after ECC1 (AUC 61 ± 37 pg/ml*72h) compared to CON (AUC 33 ± 31 pg/ml*72h; p<.05). After ECC2, the IL-6 response (AUC 43 ± 25 pg/ml*72h) remained lower than post-ECC1, but the difference was not statistically significant. Serum levels of TNF-α and of the anti-inflammatory cytokine IL-10 were below detection limits. Overall, markers of muscle damage and immune response showed high inter-individual variability. CONCLUSION: Despite maximal ECC loading of a large muscle group, no anti-inflammatory and just weak inflammatory responses were detected in healthy adults. Whether ECC elicits a different reaction in inflammatory clinical conditions is unclear. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000679532.65880.af SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 7S SP - 497 EP - 497 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Schomöller, Anne A1 - Risch, Lucie A1 - Kaplick, Hannes A1 - Schraplau, Anne A1 - Wochatz, Monique A1 - Engel, Tilman A1 - Sonnenburg, Dominik A1 - Mayer, Frank T1 - Changes in paraspinal muscle T2 times and creatine kinase after a bout of eccentric exercise T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine N2 - Eccentric (ECC) exercises might cause muscle damage, characterized by delayed-onset muscle soreness, elevated creatine kinase (CK) levels and local muscle oedema, shown by elevated T2 times in magnet resonance imaging (MRI) scans. Previous research suggests a high inter-individual difference regarding these systemic and local responses to eccentric workload. PURPOSE: To analyze ECC exercise-induced muscle damage in lumbar paraspinal muscles assessed via MRI. METHODS: Ten participants (3f/7m; 33±6y; 174±8cm; 71±12kg) were included in the study. Quantitative paraspinal muscle constitution of M. erector spinae and M. multifidius were assessed in supine position before and 72h after an intense eccentric trunk exercise bout in a mobile 1.5 tesla MRI device. MRI scans were recorded on spinal level L3 (T2-weighted TSE echo sequences, 11 slices, 2mm slice thickness, 3mm gap, echo times: 20, 40, 60, 80, 100ms, TR time: 2500ms). Muscle T2 times were calculated for manually traced regions of interest of the respective muscles with an imaging software. The exercise protocol was performed in an isokinetic device and consisted of 120sec alternating ECC trunk flexion-extension with maximal effort. Venous blood samples were taken before and 72h after the ECC exercise. Descriptive statistics (mean±SD) and t-testing for pre-post ECC exercises were performed. RESULTS: T2 times increased from pre- to post-ECC MRI measurements from 55±3ms to 79±28ms in M. erector spinae and from 62±5ms to 78±24ms in M. multifidius (p<0.001). CK increased from 126±97 U/L to 1447±20579 U/L. High SDs of T2 time and CK in post-ECC measures could be due to inter-individual reactions to ECC exercises. 3 participants showed high local and systemic reactions (HR) with T2 time increases of 120±24% (M. erector spinae) and 73±50% (M. multifidius). In comparison, the remaining 7 participants showed increases of 11±12% (M. erector spinae) and 7±9% (M. multifidius) in T2 time. Mean CK increased 9.5-fold in the 3 HR subjects compared with the remaining 7 subjects. CONCLUSIONS: The 120sec maximal ECC trunk flexion-extension protocol induced high amounts of muscle damage in 3 participants. Moderate to low responses were found in the remaining 7 subjects, assuming that inter-individual predictors play a role regarding physiological responses to ECC workload. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000685648.68626.f1 SN - 0195-9131 SN - 1530-0315 SN - 0025-7990 VL - 52 IS - 17 SP - 929 EP - 929 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Salzwedel, Annett A1 - Völler, Heinz A1 - Reibis, Rona Katharina T1 - Vocational reintegration in coronary heart disease patients - the holistic approach of the WHO biopsychosocial concept T2 - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology Y1 - 2019 U6 - https://doi.org/10.1177/2047487319850699 SN - 2047-4873 SN - 2047-4881 VL - 26 IS - 13 SP - 1383 EP - 1385 PB - Sage Publ. CY - London ER - TY - GEN A1 - Salzwedel, Annett A1 - Hadzic, Miralem A1 - Buhlert, Hermann A1 - Völler, Heinz T1 - Impact of self-assessment of return to work on employable discharge from multi-component cardiac rehabilitation T2 - European heart journal N2 - Impact of self-assessment of return to work on employable discharge from multi-component cardiac rehabilitation. Retrospective unicentric analysis of routine data from cardiac rehabilitation in patients below 65 years of age. Presentation in the "Cardiovascular rehabilitation revisited" high impact abstract session during ESC Congress 2018. Y1 - 2018 SN - 0195-668X SN - 1522-9645 VL - 39 SP - 21 EP - 22 PB - Oxford Univ. Press CY - Oxford ER - TY - GEN A1 - Rapp, Michael Armin A1 - Kluge, Ulrike A1 - Penka, Simone A1 - Vardar, Azra A1 - Aichberger, Marion Christina A1 - Mundt, Adrian P. A1 - Schouler-Ocak, Meryam A1 - Mösko, Mike A1 - Butler, Jeffrey A1 - Meyer-Lindenberg, Andreas A1 - Heinz, Andreas T1 - When local poverty is more important than your income: Mental health in minorities in inner cities T2 - World psychiatry Y1 - 2015 U6 - https://doi.org/10.1002/wps.20221 SN - 1723-8617 SN - 2051-5545 VL - 14 IS - 2 SP - 249 EP - 250 PB - Wiley-Blackwell CY - Hoboken ER - TY - GEN A1 - Pérez Chaparro, Camilo Germán Alberto A1 - Mayer, Frank A1 - Beckendorf, Claudia T1 - Cardiovascular drift response over two different constant-load exercises in healthy non-athletes BT - case study T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine N2 - Cardiovascular drift (CV-d) is a steady increase in heart rate (HR) over time while performing constant load moderate intensity exercise (CME) > 20 min. CV-d presents problems for the prescription of exercise intensity by means of HR, because the work rate (WR) during exercise must be adjusted to maintain target HR, thus disturbing the intended effect of the exercise intervention. It has been shown that the increase in HR during CME is due to changes in WR and not to CV-d. Y1 - 2019 U6 - https://doi.org/10.1249/01.mss.0000561495.15163.50 SN - 0195-9131 SN - 1530-0315 VL - 51 IS - 6 SP - 329 EP - 329 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Puschmann, Anne-Kathrin A1 - Beck, Heidrun A1 - Schiltenwolf, Marcus A1 - Wippert, Pia-Maria A1 - Mayer, Frank T1 - Distress in a longitudinal study of a population with nonspecific low back pain T2 - Psychosomatic medicine Y1 - 2017 SN - 0033-3174 SN - 1534-7796 VL - 79 SP - A20 EP - A21 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Nair, Alexandra A1 - Lin, Chiao-I A1 - Khajooei, Mina A1 - Heikkila, Mika A1 - Engel, Tilman A1 - Mayer, Frank T1 - Side comparison of knee muscle activities in response to perturbed walking of unilateral ankle instability T2 - Medicine and science in sports and exercise : MSSE N2 - Acute ankle sprain leads in 40% of all cases to chronic ankle instability (CAI). CAI is related to a variety of motor adaptations at the lower extremities. Previous investigations identified increased muscle activities while landing in CAI compared to healthy control participants. However, it remains unclear whether muscular alterations at the knee muscles are limited to the involved (unstable) ankle or are also present at the uninvolved leg. The latter might potentially indicate a risk of ankle sprain or future injury on the uninvolved leg. Purpose: To assess if there is a difference of knee muscle activities between the involved and uninvolved leg in participants with CAI during perturbed walking. Method: 10 participants (6 females; 4 males; 26±4 years; 169±9 cm; 65±7 kg) with unilateral CAI walked on a split-belt treadmill (1m/s) for 5 minutes of baseline walking and 6 minutes of perturbed walking (left and right side, each 10 perturbations). Electromyography (EMG) measurements were performed at biceps femoris (BF) and rectus femoris (RF). EMG amplitude (RMS; normalized to MVIC) were analyzed for 200ms pre-heel contact (Pre200), 100ms post heel contact (Post100) and 200ms after perturbation (Pert200). Data was analyzed by paired t-test/Wilcoxon test based on presence or absence of normal distribution (Bonferroni adjusted α level p≤ 0.0125). Results: No statistical difference was found between involved and uninvolved leg for RF (Pre200: 4±2% and 11± 22%, respectively, p= 0.878; Post100: 10± 5 and 18±31%, p=0.959; Pert200: 6±3% and 13±24%, p=0.721) as well as for BF (Pre200: 12±7% and 11±6, p=0.576; Post100: 10±7% and 9±7%, p=0.732; Pert200: 7±4 and 7±7%, p=0.386). Discussion: No side differences in muscle activity could be revealed for assessed feedforward and feedback responses (perturbed and unperturbed) in unilateral CAI. Reduced inter-individual variability of muscular activities at the involved leg might indicate a rather stereotypical response pattern. It remains to be investigated, whether muscular control at the knee is not affected by CAI, or whether both sides adapted in a similar style to the chronic condition at the ankle. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000671088.10003.6b SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 97 EP - 97 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Moser, Othmar A1 - Mueller, Alexander A1 - Tschakert, Gerhard A1 - Koehler, Gerd A1 - Lawrence, Jimmy B. A1 - Groeschl, Werner A1 - Pieber, Thomas R. A1 - Bracken, Richard M. A1 - Hofmann, Peter T1 - Exercise Prescription in Type 1 Diabetes: Should We Use Percentages of Maximum Heart Rate? T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2017 U6 - https://doi.org/10.1249/01.mss.0000519798.35679.cf SN - 0195-9131 SN - 1530-0315 VL - 49 SP - 1020 EP - 1020 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Molnar, Marco A1 - Kok, Manor A1 - Engel, Tilman A1 - Kaplic, Hannes A1 - Mayer, Frank A1 - Seel, Thomas T1 - A method for lower back motion assessment using wearable 6D inertial sensors T2 - 21st International Conference on Information Fusion (FUSION) N2 - Low back pain (LBP) is a leading cause of activity limitation. Objective assessment of the spinal motion plays a key role in diagnosis and treatment of LBP. We propose a method that facilitates clinical assessment of lower back motions by means of a wireless inertial sensor network. The sensor units are attached to the right and left side of the lumbar region, the pelvis and the thighs, respectively. Since magnetometers are known to be unreliable in indoor environments, we use only 3D accelerometer and 3D gyroscope readings. Compensation of integration drift in the horizontal plane is achieved by estimating the gyroscope biases from automatically detected initial rest phases. For the estimation of sensor orientations, both a smoothing algorithm and a filtering algorithm are presented. From these orientations, we determine three-dimensional joint angles between the thighs and the pelvis and between the pelvis and the lumbar region. We compare the orientations and joint angles to measurements of an optical motion tracking system that tracks each skin-mounted sensor by means of reflective markers. Eight subjects perform a neutral initial pose, then flexion/extension, lateral flexion, and rotation of the trunk. The root mean square deviation between inertial and optical angles is about one degree for angles in the frontal and sagittal plane and about two degrees for angles in the transverse plane (both values averaged over all trials). We choose five features that characterize the initial pose and the three motions. Interindividual differences of all features are found to be clearly larger than the observed measurement deviations. These results indicate that the proposed inertial sensor-based method is a promising tool for lower back motion assessment. KW - Inertial measurement units KW - joint angle estimation KW - human motion analysis KW - low back pain KW - back motion assessment KW - avoid magnetometers KW - validation against optical motion capture KW - drift correction Y1 - 2018 SN - 978-0-9964-5276-2 SP - 799 EP - 806 PB - IEEE CY - New York ER - TY - GEN A1 - Martinez-Valdes, Eduardo A1 - Negro, Francesco A1 - Laine, Christopher M. A1 - Falla, Deborah L. A1 - Mayer, Frank A1 - Farina, Dario T1 - Identifying motor units in longitudinal studies with high-density surface electromyography T2 - Converging clinical and engineering research on neurorehabilitation II N2 - We investigated the possibility to identify motor units (MUs) with high-density surface electromyography (HDEMG) over experimental sessions in different days. 10 subjects performed submaximal knee extensions across three sessions in three days separated by one week, while EMG was recorded from the vastus medialis muscle with high-density electrode grids. The shapes of the MU action potentials (MUAPs) over multiple channels extracted from HDEMG decomposition were matched across sessions by cross-correlation. Forty and twenty percent of the MUs decomposed could be tracked across two and three sessions, respectively (average cross correlation 0.85 +/- 0.04). The estimated properties of the matched motor units were similar across the sessions. For example, mean discharge rate and recruitment thresholds were measured with an intra-class correlation coefficient (ICCs) > 0.80. These results strongly suggest that the same MUs were indeed identified across sessions. This possibility will allow monitoring changes in MU properties following interventions or during the progression of neuromuscular disorders. Y1 - 2016 SN - 978-3-319-46669-9 SN - 978-3-319-46668-2 U6 - https://doi.org/10.1007/978-3-319-46669-9_27 SN - 2195-3562 VL - 15 SP - 147 EP - 151 PB - Springer CY - Cham ER - TY - GEN A1 - Luther, Sven A1 - Lazik, Dieter T1 - Zusammenhang zwischen Bandscheibenerkrankungen im Bereich der Lendenwirbelsäule und Merkmalen der äußeren Wirbelsäulenkontur (Abstract) Y1 - 2003 ER - TY - GEN A1 - Liu, S. A1 - Kuschpel, M. S. A1 - Schad, Daniel A1 - Heinzel, Stephan A1 - Rapp, Michael Armin A1 - Heinz, A. T1 - Effects of rest on learning processes T2 - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology Y1 - 2018 U6 - https://doi.org/10.1016/j.euroneuro.2017.12.099 SN - 0924-977X SN - 1873-7862 VL - 28 SP - S67 EP - S68 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Lin, Chiao-I A1 - Khajooei, Mina A1 - Nair, Alexandra A1 - Heikkila, Mika A1 - Kaplick, Hannes A1 - Tilman, Engel A1 - Mayer, Frank T1 - Activities of hip muscles in response to perturbed walking in individual with chronic ankle instability T2 - Medicine and science in sports and exercise : MSSE N2 - Chronic ankle instability (CAI) is not only an ankle issue, but also affects sensorimotor system. People with CAI show altered muscle activation in proximal joints such as hip and knee. However, evidence is limited as controversial results have been presented regarding changes in activation of hip muscles in CAI population. PURPOSE: To investigate the effect of CAI on activity of hip muscles during normal walking and walking with perturbations. METHODS: 8 subjects with CAI (23 ± 2 years, 171 ± 7 cm and 65 ± 4 kg) and 8 controls (CON) matched by age, height, weight and dominant leg (25 ± 3 years, 172 ± 7 cm and 65 ± 6 kg) walked shoed on a split-belt treadmill (1 m/s). Subjects performed 5 minutes of baseline walking and 6 minutes walking with 10 perturbations (at 200 ms after heel contact with 42 m/s2 deceleration impulse) on each side. Electromyography signals from gluteus medius (Gmed) and gluteus maximus (Gmax) were recorded while walking. Muscle amplitudes (Root Mean Square normalized to maximum voluntary isometric contraction) were calculated at 200 ms before heel contact (Pre200), 100 ms after heel contact (Post100) during normal walking and 200 ms after perturbations (Pert200). Differences between groups were examined using Mann Whitney U test and Bonferroni correction to account for multiple testing (adjust α level p≤ 0.0125). RESULT: In Gmed, CAI group showed lower muscle amplitude than CON group after heel contact (Post100: 18±7 % and 47±21 %, p< .01) and after walking perturbations ( 31±13 % and 62±26 %, p< .01), but not before heel contact (Pre200: 5±2 % and 11±10 %, p= 0.195). In Gmax, no difference was found between CAI and CON groups in all three time points (Pre200: 12±5 % and 17±12 %, p= 0.574; Post100: 41±21 % and 41±13 %, p= 1.00; Pert200: 79±46 % and 62±35 %, p= 0.505). CONCLUSION: People with CAI activated Gmed less than healthy control in feedback mechanism (after heel contact and walking with perturbations), but not in feedforward mechanism (before heel contact). Less activation on Gmed may affect the balance in frontal plane and increase the risk of recurrent ankle sprain, giving way or feeling ankle instability in patients with CAI during walking. Future studies should investigate the effect of Gmed strengthening or neuromuscular training on CAI rehabilitation. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000671060.98581.0b SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 94 EP - 94 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Kiefer-Trendelenburg, Thomas Hermann A1 - Völler, Heinz A1 - Nothroff, Jörg A1 - Schikora, Martin A1 - Bartels-Reinisch, Birgit A1 - Heyne, Karolin A1 - Daeschlein, Georg T1 - Prevalence of patients with multiresistant pathogens (MRP) in rehabilitation clinics T2 - Oncology Research and Treatment Y1 - 2017 SN - 2296-5270 SN - 2296-5262 VL - 40 SP - 198 EP - 198 PB - Karger CY - Basel ER - TY - GEN A1 - Kibele, Armin A1 - Granacher, Urs A1 - Mühlbauer, Thomas A1 - Behm, David George T1 - Stable, Unstable, and Metastable States of Equilibrium: Definitions and Applications to Human Movement T2 - Journal of sports science & medicine Y1 - 2015 SN - 1303-2968 VL - 14 IS - 4 SP - 885 EP - 887 PB - Department of Sports Medicine, Medical Faculty of Uludag University CY - Bursa ER - TY - GEN A1 - Khajooei, Mina A1 - Lin, Chiao-I A1 - Steffan, Müller A1 - Mayer, Frank T1 - Effect of Instability in Legpress Testing on Strength & Muscle Activity in Functional Ankle Instability T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2018 U6 - https://doi.org/:10.1249/01.mss.0000537073.01736.db SN - 0195-9131 SN - 1530-0315 VL - 50 IS - 5S SP - 602 EP - 602 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Kaminski, Jakob A1 - Schlagenhauf, Florian A1 - Rapp, Michael Armin A1 - Awasthi, Swapnil A1 - Ruggeri, Barbara A1 - Deserno, Lorenz A1 - Laura, Daedelow A1 - Banaschewski, Tobias A1 - Bokde, Arun A1 - Quinlan, Erin Burke A1 - Buechel, Christian A1 - Bromberg, Uli A1 - Desrivieres, Sylvane A1 - Flor, Herta A1 - Frouin, Vincent A1 - Garavan, Hugh A1 - Gowland, Penny A1 - Ittermann, Bernd A1 - Martinot, Jean-Luc A1 - Martinot, Marie-Laure Paillere A1 - Nees, Frauke A1 - Orfanos, Dimitri Papadopoulos A1 - Paus, Tomas A1 - Poustka, Luise A1 - Smolka, Michael A1 - Froehner, Juliane A1 - Walter, Henrik A1 - Whelan, Robert A1 - Ripke, Stephan A1 - Schumann, Gunter A1 - Heinz, Andreas T1 - Variance in Dopaminergic Markers BT - a possible marker of individual differences in IQ? T2 - Biological psychiatry : a journal of psychiatric neuroscience and therapeutics ; a publication of the Society of Biological Psychiatry KW - Intelligence KW - Dopamine KW - Epigenetic Biomarkers KW - Reward Anticipation KW - Polygenic Risk Score Y1 - 2018 U6 - https://doi.org/10.1016/j.biopsych.2018.02.311 SN - 0006-3223 SN - 1873-2402 VL - 83 IS - 9 SP - S118 EP - S118 PB - Elsevier CY - New York ER - TY - GEN A1 - Joost, Theresa Anna A1 - Brecht, Pia A1 - Mayer, Frank A1 - Cassel, Michael T1 - Feasibility of open low-field MRI measurements in adolescent athletes with spondylolisthesis T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine N2 - PURPOSE: To determine the feasibility of upright compared to supine MRI measurements to determine characteristics of the lumbar spine in AA with spondylolisthesis. METHODS: Ten AA (n=10; m/f: 4/6; 14.5±1.7y; 163±7cm; 52±8kg) from various sports, diagnosed with spondylolisthesis grade I-II Meyerding confirmed by x-ray in standing lateral view, were included. Open low-field MRI images (0.25 Tesla) in upright (82°) and supine (0°) position were evaluated by two observers. Medical imaging software was used to measure the anterior translation (AT, mm), lumbosacral joint angle (LSJA, °) and lordosis angle (LA, °). Reliability was analyzed by the intra-rater correlation coefficient (ICC) and standard error of measurements (SEM). RESULTS: Due to motion artifacts during upright position, measures of three participants had to be excluded. Between observers, AT ranged from 4.2±2.7mm to 5.5±1.9mm (ICC=0.94, SEM=0.6mm) in upright and from 4.9±2.4mm to 5.9±3.0mm (ICC=0.89, SEM=0.9mm) in supine position. LSJA varied from 5.1±2.2° to 7.3±1.5° (ICC=0.54, SEM=1.5°) in upright and from 9.8±2.5° to 10±2.4° (ICC=0.73, SEM=1.1°) in supine position. LA differed from 58.8±14.6° to 61.9±6° (ICC=0.94, SEM=1.19°) in upright and from 51.9±11.7° to 52.6±11.1° (ICC=0.98, SEM=1.59°) in supine position. CONCLUSIONS: Determination of AT and LA showed good to excellent reliability in both, upright and supine position. In contrast, reliability of LSJA had only moderate to good correlation between observers and should therefore be interpreted with caution. However, motion artifacts should be taken into consideration during upright imaging procedures. Y1 - 2020 U6 - https://doi.org/10.1249/01.mss.0000683832.74059.9d SN - 0195-9131 SN - 1530-0315 VL - 52 IS - 17 SP - 790 EP - 790 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Jekauc, Darko A1 - Brand, Ralf T1 - Editorial: How do Emotions and Feelings Regulate Physical Activity? T2 - Frontiers in psychology KW - physical activity KW - exercise KW - emotions KW - feelings KW - affect KW - regulation KW - implicit KW - enjoyment Y1 - 2017 U6 - https://doi.org/10.3389/fpsyg.2017.01145 SN - 1664-1078 VL - 8 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Hocher, Berthold A1 - Yin, Lianghong T1 - Why Current PTH Assays Mislead Clinical Decision Making in Patients with Secondary Hyperparathyroidism T2 - Nephron N2 - Preclinical studies in cell culture systems as well as in whole animal chronic kidney disease (CKD) models showed that parathyroid hormone (PTH), oxidized at the 2 methionine residues (positions 8 and 18), caused a loss of function. This was so far not considered in the development of PTH assays used in current clinical practice. Patients with advanced CKD are subject to oxidative stress, and plasma proteins (including PTH) are targets for oxidants. In patients with CKD, a considerable but variable fraction (about 70 to 90%) of measured PTH appears to be oxidized. Oxidized PTH (oxPTH) does not interact with the PTH receptor resulting in loss of biological activity. Currently used intact PTH (iPTH) assays detect both oxidized and non-oxPTH (n-oxPTH). Clinical studies demonstrated that bioactive, n-oxPTH, but not iPTH nor oxPTH, is associated with mortality in CKD patients. KW - Serum intact-parathyroid hormone level KW - Dialysis patients KW - Mortality Y1 - 2017 U6 - https://doi.org/10.1159/000455289 SN - 1660-8151 SN - 2235-3186 SN - 0028-2766 VL - 136 IS - 2 SP - 137 EP - 142 PB - Karger CY - Basel ER - TY - GEN A1 - Hasenbring, Monika Ilona A1 - Levenig, Claudia A1 - Hallner, D. A1 - Puschmann, Anne-Katrin A1 - Weiffen, A. A1 - Kleinert, Jens A1 - Belz, Johanna A1 - Schiltenwolf, Marcus A1 - Pfeifer, Ann-Christin A1 - Heidari, Jahan A1 - Kellmann, Michael A1 - Wippert, Pia-Maria T1 - Screeninginstrumente BT - mehr Licht als Schatten T2 - Der Schmerz : Organ der Deutschen Gesellschaft zum Studium des Schmerzes, der Österreichischen Schmerzgesellschaft und der Deutschen Interdisziplinären Vereinigung für Schmerztherapie Y1 - 2018 U6 - https://doi.org/10.1007/s00482-018-0340-4 SN - 0932-433X SN - 1432-2129 VL - 32 IS - 6 SP - 479 EP - 481 PB - Springer Medizin Verlag GmbH CY - Heidelberg ER - TY - GEN A1 - Gutschow, Stephan T1 - Balance und Kognition - ein funktioneller Zusammenhang! (Abstract) Y1 - 2003 ER - TY - GEN A1 - Granacher, Urs A1 - Völler, Heinz T1 - Gait speed is not magic, but is prognostically important in older patients T2 - European journal of preventive cardiology : the official ESC journal for primary & secondary cardiovascular prevention, rehabilitation and sports cardiology Y1 - 2020 U6 - https://doi.org/10.1177/2047487317744053 SN - 2047-4873 SN - 2047-4881 VL - 25 IS - 2 SP - 209 EP - 211 PB - Sage Publ. CY - London ER - TY - GEN A1 - Granacher, Urs A1 - Puta, Christian A1 - Gabriel, Holger H. W. A1 - Behm, David George A1 - Arampatzis, Adamantios T1 - Neuromuscular Training and Adaptations in Youth Athletes T2 - Frontiers in physiology KW - strength training KW - plyometric training KW - physical fitness KW - injury prevention KW - athletic performance Y1 - 2018 U6 - https://doi.org/10.3389/fphys.2018.01264 SN - 1664-042X VL - 9 PB - Frontiers Research Foundation CY - Lausanne ER - TY - GEN A1 - Gebauer, Gunther A1 - Braun, Sebastian A1 - Suaud, Charles A1 - Faure, Jean M. T1 - Die soziale Umwelt von Spitzensportlern : ein Vergleich des Spitzensports in Deutschland und Frankreich T2 - Schriftenreihe des Bundesinstituts für Sportwissenschaft Y1 - 1999 SN - 3-7780-8981-1 VL - 98 PB - Hofmann CY - Schorndorf ER - TY - GEN A1 - Garbusow, Maria A1 - Sommer, Christian A1 - Nebe, Stephan A1 - Sebold, Miriam Hannah A1 - Kuitunen-Paul, Sören A1 - Wittchen, Hans-Ulrich A1 - Smolka, Michael N. A1 - Zimmermann, Ulrich S. A1 - Rapp, Michael Armin A1 - Huys, Quentin J. M. A1 - Schlagenhauf, Florian A1 - Heinz, Andreas T1 - Multi-level evidence of general pavlovian-to-instrumental transfer in alcohol use disorder T2 - Alcoholism : clinical and experimental research ; the official journal of the American Medical Society on Alcoholism and the Research Society on Alcoholism Y1 - 2018 SN - 0145-6008 SN - 1530-0277 VL - 42 SP - 128A EP - 128A PB - Wiley CY - Hoboken ER - TY - GEN A1 - Ehmann, Lisa A1 - Zoller, Michael A1 - Minichmayr, Iris K. A1 - Schmitt, Maximilian V. A1 - Hartung, Niklas A1 - Huisinga, Wilhelm A1 - Zander, Johannes A1 - Kloft, Charlotte T1 - Development of a tool to identify intensive care patients at risk of meropenem therapy failure T2 - International Journal of Clinical Pharmacy Y1 - 2018 SN - 2210-7703 SN - 2210-7711 VL - 40 IS - 1 SP - 317 EP - 317 PB - Springer CY - Dordrecht ER - TY - GEN A1 - De Witt Huberts, Jessie A1 - Niederer, Daniel A1 - Wippert, Pia-Maria A1 - Mayer, Frank T1 - The effects of a new practical and synergetic multimodal treatment for chronic back pain on pain-related cognitions and wellbeing T2 - Psychosomatic medicine Y1 - 2017 SN - 0033-3174 SN - 1534-7796 VL - 79 IS - 4 SP - A22 EP - A23 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Chaparro, Camilo G. A. Perez A1 - Zech, Philipp A. A1 - Heinzel, Stephan A1 - Mayer, Frank A1 - Wolfarth, Bernd A1 - Rapp, Michael Armin A1 - Heissel, Andreas T1 - Effects Of Aerobic & Resistance Training On Cardiorespiratory Fitness In People Living with HIV. A Meta-analysis T2 - Medicine and science in sports and exercise : official journal of the American College of Sports Medicine Y1 - 2017 U6 - https://doi.org/10.1249/01.mss.0000519265.28705.86 SN - 0195-9131 SN - 1530-0315 VL - 49 SP - 842 EP - 842 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - GEN A1 - Burrmann, Ulrike A1 - Fussan, Nancy A1 - Nobis, Tina T1 - MädchenStärken durch Straßenfußball T2 - ASS-Materialien Nr. 22 Y1 - 2005 CY - Potsdam ER - TY - GEN A1 - Burrmann, Ulrike T1 - "KICK Brandenburg" die Rolle von Sport in der gewaltpräventiven Jugendareit Y1 - 2005 ER - TY - GEN A1 - Brand, Ralf A1 - Ulrich, Lukas T1 - I can see it in your face BT - Exercisers’ and non-exercisers’ automatic affective valuations of exercise T2 - Journal of sport & exercise psychology Y1 - 2018 U6 - https://doi.org/10.1123/jsep.2018-0169 SN - 0895-2779 SN - 1543-2904 VL - 40 SP - S77 EP - S78 PB - Human Kinetics Publ. CY - Champaign ER - TY - GEN A1 - Baur, Jürgen T1 - Sportvereine und ihre Jugendlichen: eine erwartungsvolle Beziehung Y1 - 2004 ER - TY - GEN A1 - Awasthi, Swapnil A1 - Kaminski, Jakob A1 - Rapp, Michael Armin A1 - Schlagenhauf, Florian A1 - Walter, Henrik A1 - Ruggeri, Barbara A1 - Ripke, Stephan A1 - Schumann, Gunter A1 - Heinz, Andreas T1 - A neural signature of malleability BT - general intelligence correlates with ventral striatal activation and epigenetic makers of dopamine neurotransmission T2 - European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology N2 - General intelligence has a substantial genetic background in children, adolescents, and adults, but environmental factors also strongly correlate with cognitive performance as evidenced by a strong (up to one SD) increase in average intelligence test results in the second half of the previous century. This change occurred in a period apparently too short to accommodate radical genetic changes. It is highly suggestive that environmental factors interact with genotype by possible modification of epigenetic factors that regulate gene expression and thus contribute to individual malleability. This modification might as well be reflected in recent observations of an association between dopamine-dependent encoding of reward prediction errors and cognitive capacity, which was modulated by adverse life events. Y1 - 2019 U6 - https://doi.org/10.1016/j.euroneuro.2017.08.139 SN - 0924-977X SN - 1873-7862 VL - 29 SP - S858 EP - S859 PB - Elsevier CY - Amsterdam ER -