TY - JOUR A1 - Yang, Xiao Hui A1 - Jaiser, Frank A1 - Stiller, Burkhard A1 - Neher, Dieter A1 - Galbrecht, Frank A1 - Scherf, Ullrich T1 - Efficient polymer electrophosphoreseent devices with interfacial layers JF - Advanced functional materials N2 - It is shown that several polymers can form insoluble interfacial layers on a poly (ethylenedioxythiophene):poly(styrene sulfonate) (PEDOT:PSS) layer after annealing of the double-layer structure. The thickness of the interlayer is dependent on the characteristics of the underlying PEDOT.PSS and the molecular weight of the polymers. It is further shown that the electronic structures of the interlayer polymers have a significant effect on the properties of red-light-emitting polymer-based electrophosphorescent devices. Upon increasing the highest occupied molecular orbital and lowest unoccupied molecular orbital positions, a significant increase in current density and device efficiency is observed. This is attributed to efficient blocking of electrons in combination with direct injection of holes from the interlayer to the phosphorescent dye. Upon proper choice of the interlayer polymer, efficient red, polymer-based electrophosphorescent devices with a peak luminance efficiency of 5.5 cd A(-1) (external quantum efficiency = 6 %) and a maximum power-conversion efficiency of 5 Im W-1 can be realized. Y1 - 2006 U6 - https://doi.org/10.1002/adfm.200500834 SN - 1616-301X SN - 1616-3028 VL - 16 IS - 16 SP - 2156 EP - 2162 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Lange, Birger A1 - Wagner, Jürgen A1 - Zentel, Rudolf T1 - Fabrication of robust high-quality ORMOCER (R) inverse opals JF - Macromolecular rapid communications N2 - The nanostructuring of ORMOCER (R) to form inverse opals is described. For this purpose a polymer opal is used as a template and infiltrated with liquid ORMOCER (R). After photopolymerization of the resin the host opal is dissolved in tetrahydrofuran and an ORMOCER (R) inverse opal is obtained. It shows excellent periodicity (by SEM) and optical properties to reveal a high degree of face centered cubic order. This replication process leads to a nanostructured photonic crystal with the outstanding mechanical properties of ORMOCER (R) and high temperature stability up to 350 degrees C. KW - colloids KW - inverse opals KW - ORMOCER (R) KW - photonic crystal KW - self-assembly Y1 - 2006 U6 - https://doi.org/10.1002/marc.200600429 SN - 1022-1336 VL - 27 SP - 1746 EP - 1751 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Baptista, Murilo da Silva A1 - Grebogi, Celso A1 - Koberle, Roland T1 - Dynamically multilayered visual system of the multifractal fly JF - Physical review letters Y1 - 2006 U6 - https://doi.org/10.1103/PhysRevLett.97.178102 SN - 0031-9007 VL - 97 IS - 17 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Green, Antony Dubach T1 - The independence of phonology and morphology: The Celtic mutations JF - Lingua : international review of general linguistics N2 - One of the most important insights of Optimality Theory (Prince and Smolensky, 1993) is that phonological processes can be reduced to the interaction between faithfulness and universal markedness principles. In the most constrained version of the theory, all phonological processes should be thus reducible. This hypothesis is tested by alternations that appear to be phonological but in which universal markedness principles appear to play no role. If we are to pursue the claim that all phonological processes depend on the interaction of faithfulness and markedness, then processes that are not dependent on markedness must lie outside phonology. In this paper I will examine a group of such processes, the initial consonant mutations of the Celtic languages, and argue that they belong entirely to the morphology of the languages, not the phonology. KW - Celtic mutations KW - word-based morphology KW - optimality theory Y1 - 2006 U6 - https://doi.org/10.1016/j.lingua.2004.09.002 SN - 0024-3841 VL - 116 IS - 11 SP - 1946 EP - 1985 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - ten Freyhaus, Henrik A1 - Huntgeburth, Michael A1 - Winger, Kirstin A1 - Bäumer, Anselm T. A1 - Vantler, Marius A1 - Bekhite, Mohamed M. A1 - Wartenberg, Maria A1 - Sauer, Heinrich A1 - Sparwel, Jan A1 - Rosenkranz, Stephan T1 - Inhibition of ROS liberation attenuates PDGF-Dependent chemotaxis, but not proliferation in vascular smooth muscle cells - Critical role of Src kinase T2 - Circulation : an American Heart Association journal Y1 - 2006 SN - 0009-7322 VL - 114 SP - 296 EP - 297 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Torjek, Otto A1 - Witucka-Wall, Hanna A1 - Meyer, Rhonda C. A1 - von Korff, Maria A1 - Kusterer, Barbara A1 - Rautengarten, Carsten A1 - Altmann, Thomas T1 - Segregation distortion in Arabidopsis C24/Col-0 and Col-0/C24 recombinant inbred line populations is due to reduced fertility caused by epistatic interaction of two loci JF - Theoretical and applied genetics N2 - A new large set of reciprocal recombinant inbred lines (RILs) was created between the Arabidopsis accessions Col-0 and C24 for quantitative trait mapping approaches, consisting of 209 Col-0 x C24 and 214 C24 x Col-0 F-7 RI lines. Genotyping was performed using 110 evenly distributed framework single nucleotide polymorphism markers, yielding a genetic map of 425.70 cM, with an average interval of 3.87 cM. Segregation distortion (SD) was observed in several genomic regions during the construction of the genetic map. Linkage disequilibrium analysis revealed an association between a distorted region at the bottom of chromosome V and a non-distorted region on chromosome IV. A detailed analysis of the RILs for these two regions showed that an SD occurred when homozygous Col-0 alleles on chromosome IV coincided with homozygous C24 alleles at the bottom of chromosome V. Using nearly isogenic lines segregating for the distorted region we confirmed that this genotypic composition leads to reduced fertility and fitness. Y1 - 2006 U6 - https://doi.org/10.1007/s00122-006-0402-3 SN - 0040-5752 VL - 113 SP - 1551 EP - 1561 PB - Springer CY - Berlin ER - TY - JOUR A1 - Hobbhahn, Nina A1 - Küchmeister, Heike A1 - Porembski, Stefan T1 - Pollination biology of mass flowering terrestrial Utricularia species (Lentibulariaceae) in the Indian Western Ghats JF - Plant biology N2 - The pollination biology of three mass flowering Utricularia species of the Indian Western Ghats, U. albocaerulea, U. purpurascens, and U. reticulata, was studied for the first time by extensive observation of flower visitors, pollination experiments, and nectar analyses. The ephemerality of the Utricularia habitats on lateritic plateaus, weather conditions adverse to insects, lack of observations of flower visitors to other Utricularia spp., and the predominance of at least. facultative autogamy in the few Utricularia species studied so far suggested that an autogamous breeding system is the common case in the genus. In contrast, we showed that the studied populations are incapable of autonomous selfing, or that it is an event of negligible rarity, although P/O was similarily low as in autogamous species investigated by other authors. In all three species the spatial arrangement of the reproductive organs makes an insect vector necessary for pollen transfer between and within flowers. However, U. purpurascens and U. reticulata are highly self-compatible, which allows for visitor-mediated auto-selfing and geitonogamy on inflorescence and clone level. Floral nectar is present in extremely small volumes in all three species, but sugar concentrations are high. More than 50 species of bees, butterflies, moths, hawk moths, and clipterans were observed to visit the flowers, and flower morphology facilitated pollination by all observed visitors. The results are discussed in the context of the phenological characteristics of the studied species, especially the phenomenon of mass flowering, and the environmental conditions of their habitats. KW - Lentibulariaceae KW - Utricularia KW - mass flowering KW - carnivory KW - India KW - Western Ghats KW - pollination Y1 - 2008 U6 - https://doi.org/10.1055/s-2006-924566 SN - 1435-8603 VL - 8 IS - 6 SP - 791 EP - 804 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Montbrio, Ernest A1 - Pazo, Diego A1 - Schmidt, Jürgen T1 - Time delay in the Kuramoto model with bimodal frequency distribution JF - Physical review : E, Statistical, nonlinear and soft matter physics N2 - We investigate the effects of a time-delayed all-to-all coupling scheme in a large population of oscillators with natural frequencies following a bimodal distribution. The regions of parameter space corresponding to synchronized and incoherent solutions are obtained both numerically and analytically for particular frequency distributions. In particular, we find that bimodality introduces a new time scale that results in a quasiperiodic disposition of the regions of incoherence. Y1 - 2006 U6 - https://doi.org/10.1103/PhysRevE.74.056201 SN - 1539-3755 VL - 74 PB - APS CY - College Park ER - TY - JOUR A1 - Hahnewald, Rita A1 - Leimkühler, Silke A1 - Vilaseca, Antonia A1 - Acquaviva-Bourdain, Cecile A1 - Lenz, Ulrike A1 - Reiss, Jochen T1 - A novel MOCS2 mutation reveals coordinated expression of the small and large subunit of molybdopterin synthase JF - Molecular genetics and metabolism N2 - The small and large subunits of molybdopterin (MPT) synthase (MOCS2A and MOCS2B), are both encoded by the MOCS2 gene in overlapping and shifted open reading frames (ORFs), which is a highly unusual structure for eukaryotes. Theoretical analysis of genomic sequences suggested that the expression of these overlapping ORFs is facilitated by the use of alternate first exons leading to alternative transcripts. Here, we confirm the existence of these overlapping transcripts experimentally. Further, we identified a deletion in a molybdenum cofactor deficient patient, which removes the start codon for the small subunit (MOCS2A). We observed undisturbed production of both transcripts, while Western blot analysis demonstrated that MOCS2B, the large subunit, is unstable in the absence of MOCS2A. This reveals new insights into the expression of this evolutionary ancient anabolic system. KW - molybdenum cofactor deficiency KW - MOCS2 KW - overlapping reading frames Y1 - 2006 U6 - https://doi.org/10.1016/j.ymgme.2006.04.008 SN - 1096-7192 VL - 89 IS - 3 SP - 210 EP - 213 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Konrad-Schmolke, Matthias A1 - Babist, Jochen A1 - Handy, Mark R. A1 - O'brien, Patrick J. T1 - The physico-chemical properties of a subducted slab from garnet zonation patterns (Sesia Zone, Western Alps) JF - Journal of petrology N2 - Garnets in continentally derived high-pressure (HP) rocks of the Sesia Zone (Western Alps) exhibit three different chemical zonation patterns, depending on sample locality. Comparison of observed garnet zonation patterns with thermodynamically modelled patterns shows that the different patterns are caused by differences in the water content of the subducted protoliths during prograde metamorphism. Zonation patterns of garnets in water-saturated host rocks show typical prograde chemical zonations with steadily increasing pyrope content and increasing XMg, together with bell-shaped spessartine patterns. In contrast, garnets in water-undersaturated rocks have more complex zonation patterns with a characteristic decrease in pyrope and XMg between core and inner rim. In some cases, garnets show an abrupt compositional change in core-to-rim profiles, possibly due to water-undersaturation prior to HP metamorphism. Garnets from both water-saturated and water-undersaturated rocks show signs of intervening growth interruptions and core resorption. This growth interruption results from bulk-rock depletion caused by fractional garnet crystallization. The water content during burial influences significantly the physical properties of the subducted rocks. Due to enhanced garnet crystallization, water-undersaturated rocks, i.e. those lacking a free fluid phase, become denser than their water-saturated equivalents, facilitating the subduction of continental material. Although water-bearing phases such as phengite and epidote are stable up to eclogite-facies conditions in these rocks, dehydration reactions during subduction are lacking in water-undersaturated rocks up to the transition to the eclogite facies, due to the thermodynamic stability of such hydrous phases at high P-T conditions. Our calculations show that garnet zonation patterns strongly depend on the mineral parageneses stable during garnet growth and that certain co-genetic mineral assemblages cause distinct garnet zonation patterns. This observation enables interpretation of complex garnet growth zonation patterns in terms of garnet-forming reactions and water content during HP metamorphism, as well determination of detailed P-T paths. KW - dehydration KW - high-pressure metamorphism KW - Sesia Zone KW - subduction KW - thermodynamic modelling Y1 - 2006 U6 - https://doi.org/10.1093/petrology/egl039 SN - 0022-3530 VL - 47 IS - 11 SP - 2123 EP - 2148 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Rauschmann, Michael A. A1 - Huggenberger, Stefan A1 - Kossatz, Lars Swen A1 - Oelschläger, Helmut H. A. T1 - Head morphology in perinatal dolphins: A window into phylogeny and ontogeny JF - Journal of morphology N2 - In this paper on the ontogenesis and evolutionary biology of odontocete cetaceans (toothed whales), we investigate the head morphology of three perinatal pantropical spotted dolphins (Stenella attenuata) with the following methods: computer-assisted tomography, magnetic resonance imaging, conventional X-ray imaging, cryo-sectioning as well as gross dissection. Comparison of these anatomical methods reveals that for a complete structural analysis, a combination of modern imaging techniques and conventional morphological methods is needed. In addition to the perinatal dolphins, we include series of microslides of fetal odontocetes (S. attenuata, common dolphin Delphinus delphis, narwhal Monodon monoceros). In contrast to other mammals, newborn cetaceans represent an extremely precocial state of development correlated to the fact that they have to swim and surface immediately after birth. Accordingly, the morphology of the perinatal dolphin head is very similar to that of the adult. Comparison with early fetal stages of dolphins shows that the ontogenetic change from the general mammalian bauplan to cetacean organization was characterized by profound morphological transformations of the relevant organ systems and roughly seems to parallel the phylogenetic transition. from terrestrial ancestors to modern odontocetes. KW - pantropical spotted dolphin KW - Stenella attenuata KW - comparative head morphology KW - ontogenesis KW - phylogenesis Y1 - 2006 U6 - https://doi.org/10.1002/jmor.10477 SN - 0362-2525 SN - 1097-4687 VL - 267 IS - 11 SP - 1295 EP - 1315 PB - Wiley-Blackwell CY - Hoboken ER - TY - JOUR A1 - Hoie, Lars H. A1 - Sjoholm, Ake A1 - Guldstrand, Marie A1 - Zunft, Hans-Joachim Franz A1 - Lueder, Wolfgang A1 - Graubaum, Hans-Joachim A1 - Grünwald, Jörg T1 - Ultra heat treatment destroys cholesterol-lowering effect of soy protein JF - International journal of food sciences and nutrition N2 - A randomized, placebo-controlled, double-blind clinical study was performed to investigate the dose-dependent response of serum cholesterol after consuming an ultra-heat-treated milk containing a soy protein preparation. Eighty hypercholesterolemic subjects were assigned to one of four study groups receiving 12.5 or 25 g soy protein (active treatment) or casein (placebo) daily over a period of 4 weeks. The trial substances were provided as ready-made, ultra-heated milk preparations. Before and after the treatment, serum concentrations of total, low-density lipoprotein, and high-density lipoprotein cholesterol were determined. Unexpectedly, at the end of the study, low-density lipoprotein cholesterol concentrations were significantly increased compared with baseline in all study groups. The magnitude of this increase (17 - 19%) was similar in all active and placebo study groups. Soy protein supplements previously shown to be effective in reducing serum cholesterol had in this study no such lipid-lowering effect after ultra heat treatment. KW - soy KW - protein KW - cholesterol KW - ultra heat treatment Y1 - 2006 U6 - https://doi.org/10.1080/09637480601009059 SN - 0963-7486 VL - 57 SP - 512 EP - 519 PB - Taylor & Francis CY - Abingdon ER - TY - JOUR A1 - Dornhege, Guido A1 - Blankertz, Benjamin A1 - Krauledat, Matthias A1 - Losch, Florian A1 - Curio, Gabriel A1 - Müller, Klaus-Robert T1 - Combined optimization of spatial and temporal filters for improving brain-computer interfacing JF - IEEE transactions on bio-medical electronics N2 - Brain-computer interface (BCI) systems create a novel communication channel from the brain to an output de ice by bypassing conventional motor output pathways of nerves and muscles. Therefore they could provide a new communication and control option for paralyzed patients. Modern BCI technology is essentially based on techniques for the classification of single-trial brain signals. Here we present a novel technique that allows the simultaneous optimization of a spatial and a spectral filter enhancing discriminability rates of multichannel EEG single-trials. The evaluation of 60 experiments involving 22 different subjects demonstrates the significant superiority of the proposed algorithm over to its classical counterpart: the median classification error rate was decreased by 11%. Apart from the enhanced classification, the spatial and/or the spectral filter that are determined by the algorithm can also be used for further analysis of the data, e.g., for source localization of the respective brain rhythms. KW - brain-computer interface KW - common spatial patterns KW - EEG KW - event-related desynchronization KW - single-trial-analysis Y1 - 2006 U6 - https://doi.org/10.1109/TBME.2006.883649 SN - 0018-9294 VL - 53 IS - 11 SP - 2274 EP - 2281 PB - IEEE CY - New York ER - TY - JOUR A1 - Schweigert, Florian J. A1 - Gericke, Beate A1 - Wolfram, Wiebke A1 - Kaisers, Udo A1 - Dudenhausen, Joachim W. T1 - Peptide and protein profiles in serum and follicular fluid of women undergoing IVF JF - Human reproduction N2 - BACKGROUND: Proteins and peptides in human follicular fluid originate from plasma or are produced by follicular structures. Compositional changes reflect oocyte maturation and can be used as diagnostic markers. The aim of the study was to determine protein and peptide profiles in paired serum and follicular fluid samples from women undergoing IVF. METHODS: Surface-enhanced laser desorption and ionization-time of flight-mass spectrometry (SELDI-TOF-MS) was used to obtain characteristic protein pattern. RESULTS: One hundred and eighty-six individual MS signals were obtained from a combination of enrichment on strong anion exchanger (110), weak cation exchanger (52) and normal phase surfaces (24). On the basis of molecular masses, isoelectric points and immunoreactivety, four signals were identified as haptoglobin (alpha(1)- and alpha(2)-chain), haptoglobin 1 and transthyretin (TTR). Immunological and MS characteristics of the TTR : retinol-binding protein (RBP) transport complex revealed no microheterogeneity differences between serum and follicular fluid. Discriminatory patterns arising from decision-tree-based classification and regression analysis distinguished between serum and follicular fluid with a sensitivity and specificity of 100%. CONCLUSIONS: Quantitative and qualitative differences indicate selective transport processes rather than mere filtration across the blood-follicle barrier. Identified proteins as well as characteristic peptide and/or protein signatures might emerge as potential candidates for diagnostic markers of follicle and/or oocyte maturation and thus oocyte quality. KW - human follicular fluid KW - peptide KW - protein KW - proteome KW - serum Y1 - 2006 U6 - https://doi.org/10.1093/humrep/del257 SN - 0268-1161 VL - 21 IS - 11 SP - 2960 EP - 2968 PB - Univ. Press CY - Oxford ER - TY - JOUR A1 - Garcia, A. L. A1 - Steiniger, J. A1 - Reich, S. C. A1 - Weickert, M. O. A1 - Harsch, I. A1 - Machowetz, A. A1 - Mohlig, M. A1 - Spranger, Joachim A1 - Rudovich, N. N. A1 - Meuser, F. A1 - Doerfer, J. A1 - Katz, N. A1 - Speth, M. A1 - Zunft, Hans-Joachim Franz A1 - Pfeiffer, Andreas F. H. A1 - Koebnick, Corinna T1 - Arabinoxylan fibre consumption improved glucose metabolism, but did not affect serum adipokines in subjects with impaired glucose tolerance JF - Hormone and metabolic research N2 - The consumption of arabinoxylan, a soluble fibre fraction, has been shown to improve glycemic control in type 2 diabetic subjects. Soluble dietary fibre may modulate gastrointestinal or adipose tissue hormones regulating food intake. The present study investigated the effects of arabinoxylan consumption on serum glucose, insulin, lipids, leptin, adiponectin and resistin in subjects with impaired glucose tolerance. In a randomized, single-blind, controlled, crossover intervention trial, 11 adults consumed white bread rolls as either placebo or supplemented with 15g arabinoxylan for 6 weeks with a 6-week washout period. Fasting serum glucose, insulin, triglycerides, unesterified fatty acids, apolipoprotein A1 and B, adiponectin, resistin and leptin were assessed before and after intervention. Fasting serum glucose, serum triglycerides and apolipoprotein A-1 were significantly lower during arabinoxylan consumption compared to placebo (p = 0.029, p = 0.047; p = 0.029, respectively). No effects of arabinoxylan were observed for insulin, adiponectin, leptin and resistin as well as for apolipoprotein B, and unesterified fatty acids. In conclusion, the consumption of AX in subjects with impaired glucose tolerance improved fasting serum glucose, and triglycerides. However, this beneficial effect was not accompanied by changes in fasting adipokine concentrations. KW - dietary fibre KW - arabinoxylan KW - adiponectin KW - resistin KW - leptin Y1 - 2006 U6 - https://doi.org/10.1055/s-2006-955089 SN - 0018-5043 VL - 38 IS - 2 SP - 761 EP - 766 PB - Thieme CY - Stuttgart ER - TY - JOUR A1 - Mohsen, Ayman A1 - Kind, Rainer A1 - Sobolev, Stephan Vladimir A1 - Weber, Michael T1 - Thickness of the lithosphere east of the Dead Sea Transform JF - Geophysical journal international N2 - We use the S receiver function method to study the lithosphere at the Dead Sea Transform (DST). A temporary network of 22 seismic broad-band stations was operated on both sides of the DST from 2000 to 2001 as part of the DESERT project. We also used data from six additional permanent broad-band seismic stations at the DST and in the surrounding area, that is, in Turkey, Saudi Arabia, Egypt and Cyprus. Clear S-to-P converted phases from the crust-mantle boundary (Moho) and a deeper discontinuity, which we interpret as lithosphere-asthenosphere boundary (LAB) have been observed. The Moho depth (30-38 km) obtained from S receiver functions agrees well with the results from P receiver functions and other geophysical data. We observe thinning of the lithosphere on the eastern side of the DST from 80 km in the north of the Dead Sea to about 65 km at the Gulf of Aqaba. On the western side of the DST, the few data indicate a thin LAB of about 65 km. For comparison, we found a 90-km-thick lithosphere in eastern Turkey and a 160-km-thick lithosphere under the Arabian shield, respectively. These observations support previous suggestions, based on xenolith data, heat flow observations, regional uplift history and geodynamic modelling, that the lithosphere around DST has been significantly thinned in the Late Cenozoic, likely following rifting and spreading of the Red Sea. KW - Dead Sea Transform KW - S receiver functions KW - thickness of the lithosphere Y1 - 2006 U6 - https://doi.org/10.1111/j.1365-246X.2006.03185.x SN - 0956-540X SN - 1365-246X VL - 167 IS - 2 SP - 845 EP - 852 PB - Blackwell CY - Oxford ER - TY - JOUR A1 - Moehlig, M. A1 - Floeter, A. A1 - Spranger, Joachim A1 - Weickert, Martin O. A1 - Schill, T. A1 - Schloesser, H. W. A1 - Brabant, G. A1 - Pfeiffer, Andreas F. H. A1 - Selbig, Joachim A1 - Schoefl, C. T1 - Predicting impaired glucose metabolism in women with polycystic ovary syndrome by decision tree modelling JF - Diabetologia : journal of the European Association for the Study of Diabetes (EASD) N2 - Aims/hypothesis Polycystic ovary syndrome (PCOS) is a risk factor of type 2 diabetes. Screening for impaired glucose metabolism (IGM) with an OGTT has been recommended, but this is relatively time-consuming and inconvenient. Thus, a strategy that could minimise the need for an OGTT would be beneficial. Materials and methods Consecutive PCOS patients (n=118) with fasting glucose < 6.1 mmol/l were included in the study. Parameters derived from medical history, clinical examination and fasting blood samples were assessed by decision tree modelling for their ability to discriminate women with IGM (2-h OGTT value >= 7.8 mmol/l) from those with NGT. Results According to the OGTT results, 93 PCOS women had NGT and 25 had IGM. The best decision tree consisted of HOMA-IR, the proinsulin:insulin ratio, proinsulin, 17-OH progesterone and the ratio of luteinising hormone:follicle-stimulating hormone. This tree identified 69 women with NGT. The remaining 49 women included all women with IGM (100% sensitivity, 74% specificity to detect IGM). Pruning this tree to three levels still identified 53 women with NGT (100% sensitivity, 57% specificity to detect IGM). Restricting the data matrix used for tree modelling to medical history and clinical parameters produced a tree using BMI, waist circumference and WHR. Pruning this tree to two levels separated 27 women with NGT (100% sensitivity, 29% specificity to detect IGM). The validity of both trees was tested by a leave-10%-out cross-validation. Conclusions/interpretation Decision trees are useful tools for separating PCOS women with NGT from those with IGM. They can be used for stratifying the metabolic screening of PCOS women, whereby the number of OGTTs can be markedly reduced. KW - decision tree KW - HOMA KW - impaired glucose tolerance KW - insulin KW - insulin resistance KW - polycystic ovary syndrome KW - proinsulin KW - type 2 diabetes mellitus Y1 - 2006 U6 - https://doi.org/10.1007/s00125-006-0395-0 SN - 0012-186X VL - 49 SP - 2572 EP - 2579 PB - Springer CY - Berlin ER - TY - JOUR A1 - Oberauer, Klaus T1 - Reasoning with conditionals: A test of formal models of four theories JF - Cognitive psychology N2 - The four dominant theories of reasoning from conditionals are translated into formal models: The theory of mental models (Johnson-Laird, P. N., & Byrne, R. M. J. (2002). Conditionals: a theory of meaning, pragmatics, and inference. Psychological Review, 109, 646-678), the suppositional theory (Evans, J. S. B. T., & Over, D. E. (2004). If. Oxford: Oxford University Press), a dual-process variant of the model theory (Verschueren, N., Schaeken, W., & d'Ydewalle, G. (2005). A dual-process specification of causal conditional reasoning. Thinking & Reasoning, 11, 278-293), and the probabilistic theory (Oaksford, M., Chater, N., & Larkin, J. (2000). Probabilities and polarity biases in conditional inference. Journal of Experimental Psychology: Learning, Memory, and Cognition, 26, 883-899). The first three theories are formalized as multinomial models. The models are applied to the frequencies of patterns of acceptance or rejection across the four basic inferences modus ponens, acceptance of the consequent, denial of the antecedent, and modus tollens. Model fits are assessed for two large data sets, one representing reasoning with abstract, basic conditionals, the other reflecting reasoning with pseudo-realistic causal and non-causal conditionals. The best account of the data was provided by a modified version of the mental-model theory, augmented by directionality, and by the dual-process model. KW - conditionals KW - reasoning KW - multinomial models Y1 - 2006 U6 - https://doi.org/10.1016/j.cogpsych.2006.04.001 SN - 0010-0285 VL - 53 IS - 3 SP - 238 EP - 283 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Singh, Jasbir A1 - Dani, Harinder M. A1 - Sharma, Reeta A1 - Steinberg, Pablo T1 - Inhibition of the biosynthesis of SRP polypeptides and secretory proteins by aflatoxin B-1 can disrupt protein targeting JF - Cell biochemistry and function N2 - Cell culture and western blotting studies revealed that aflatoxin B-1 (AFB(1)) inhibits the biosynthesis of two of the constituent polypeptides of signal recognition particle (SRP) (SRP54 and 72). SRP escorts polyribosomes carrying signal peptides from free form in the cytosol to the bound form on endoplasmic reticulum (ER) membrane during protein targeting. These effects of AFB(1) on SRP biosynthesis may inhibit the formation of functional SRP Our experiments have further shown that AFB(1) also inhibits the biosynthesis/translocation of a secretory protein, preprolactin, which fails to appear in the lumen of ER consequent to the treatment with this hepatocarcinogen. The results of the experiments presented in this article therefore enable us to infer for the first time that aflatoxin B-1 may inhibit the functioning of SRP as an escort and deplete the ER of polyribosomes for secretory protein synthesis. As these secretory proteins are important components of the plasma membrane, gap junctions and intercellular matrix, their absence from these locations could disturb cell to cell communication leading to tumorigenesis. KW - aflatoxin B-1 KW - SRP KW - protein targeting KW - protein translocation KW - western blotting Y1 - 2005 U6 - https://doi.org/10.1027/cbf.1285 SN - 0263-6484 VL - 24 SP - 507 EP - 510 PB - Wiley CY - Chichester ER - TY - JOUR A1 - Baur, Heiner A1 - Müller, Steffen A1 - Hirschmüller, Anja A1 - Huber, Georg A1 - Mayer, Frank T1 - Reactivity, stability, and strength performance capacity in motor sports JF - British journal of sports medicine : the journal of sport and exercise medicine N2 - Background: Racing drivers require multifaceted cognitive and physical abilities in a multitasking situation. A knowledge of their physical capacities may help to improve fitness and performance. Objective: To compare reaction time, stability performance capacity, and strength performance capacity of elite racing drivers with those of age-matched, physically active controls. Methods: Eight elite racing drivers and 10 physically active controls matched for age and weight were tested in a reaction and determination test requiring upper and lower extremity responses to visual and audio cues. Further tests comprised evaluation of one-leg postural stability on a two-dimensional moveable platform, measures of maximum strength performance capacity of the extensors of the leg on a leg press, and a test of force capacity of the arms in a sitting position at a steering wheel. An additional arm endurance test consisted of isometric work at the steering wheel at + 30 degrees and -30 degrees where an eccentric threshold load of 30 N.m was applied. Subjects had to hold the end positions above this threshold until exhaustion. Univariate one way analysis of variance (alpha = 0.05) including a Bonferroni adjustment was used to detect group differences between the drivers and controls. Results: The reaction time of the racing drivers was significantly faster than the controls ( p = 0.004). The following motor reaction time and reaction times in the multiple determination test did not differ between the groups. No significant differences (p> 0.05) were found for postural stability, leg extensor strength, or arm strength and endurance. Conclusions: Racing drivers have faster reaction times than age-matched physically active controls. Further development of motor sport-specific test protocols is suggested. According to the requirements of motor racing, strength and sensorimotor performance capacity can potentially be improved. Y1 - 2006 U6 - https://doi.org/10.1136/bjsm.2006.025783 SN - 0306-3674 VL - 40 SP - 906 EP - 910 PB - BMJ Publ. Group CY - London ER - TY - JOUR A1 - Teixeira, C. V. A1 - Blanzat, Muriel A1 - Koetz, Joachim A1 - Rico-Lattes, I. A1 - Brezesinski, Gerald T1 - In-plane miscibility and mixed bilayer microstructure in mixtures of catanionic glycolipids and zwitterionic phospholipids JF - Biochimica et biophysica acta : Biomembranes N2 - SAXS/WAXS studies were performed in combination with freeze fracture electron microscopy using mixtures of a new Gemini catanionic surfactant (Gem 16-12, formed by two sugar groups bound by a hydrocarbon spacer with 12 carbons and two 16-carbon chains) and the zwitterionic phospholipid 1,2-dipalmitoyl-sn-glycero-3-phosphocholine(DPPC) to establish the phase diagram. Gem 16-12 in water forms bilayers with the same amount of hydration water as DPPC. A frozen interdigitated phase with a low hydration number is observed below room temperature. The kinetics of the formation of this crystalline phase is very slow. Above the chain melting temperature, multilayered vesicles are formed. Mixing with DPPC produces mixed bilayers above the corresponding chain melting temperature. At room temperature, partially lamellar aggregates with local nematic order are observed. Splitting of infinite lamellae into discs is linked to immiscibility in frozen state. The ordering process is always accompanied by dehydration of the system. As a consequence, an unusual order-disorder phase transition upon cooling is observed. KW - SAXS KW - bilayer KW - gemini surfactant KW - ordering process KW - Anti-HIV KW - miscibility Y1 - 2006 U6 - https://doi.org/10.1016/j.bbamem.2006.05.025 SN - 0005-2736 VL - 1758 SP - 1797 EP - 1808 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Wronski, Torsten A1 - Apio, Ann A1 - Plath, Martin T1 - Activity patterns of bushbuck (Tragelaphus scriptus) in Queen Elizabeth National Park JF - Behavioural processes N2 - Activity patterns and time budgets of bushbuck (Tragelaphus scriptus) were studied in a free-ranging population in Queen Elizabeth National Park, Uganda from August 2000 to January 2002. We investigated differences in activity patterns in relation to daytime, season, sun radiation, moonlight, age and sex. Bushbuck were found to show peak activities around sunrise and at dawn. No difference in the mean activity rates was found between the dry and wet season. Daytime activity was not predicted by differences in sun radiation, nor was nighttime activity predicted by the presence or absence of moonlight. We found the activity of adult territorial males to be strongly positively correlated with that of females, whereas the activity of young-adult non-territorial males was not significantly correlated with the activity of females. This suggests that young-adult males shift their peak activity to phases when adult territorial males are less active. KW - activity patterns KW - bushbuck KW - tragelaphini KW - ungulate behaviour KW - Uganda Y1 - 2006 U6 - https://doi.org/10.1016/j.beproc.2006.08.003 SN - 0376-6357 VL - 73 IS - 3 SP - 333 EP - 341 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Bordihn, Henning A1 - Holzer, Markus T1 - Programmed grammars and their relation to the LBA problem JF - Acta informatica N2 - We consider generating and accepting programmed grammars with bounded degree of non-regulation, that is, the maximum number of elements in success or in failure fields of the underlying grammar. In particular, it is shown that this measure can be restricted to two without loss of descriptional capacity, regardless of whether arbitrary derivations or left-most derivations are considered. Moreover, in some cases, precise characterizations of the linear bounded automaton problem in terms of programmed grammars are obtained. Thus, the results presented in this paper shed new light on some longstanding open problem in the theory of computational complexity. KW - programmed grammars KW - accepting grammars KW - LBA problem KW - degree of non-regulation KW - leftmost derivations Y1 - 2006 U6 - https://doi.org/10.1007/s00236-006-0017-9 SN - 0001-5903 VL - 43 SP - 223 EP - 242 PB - Elsevier CY - New York ER - TY - JOUR A1 - Kozlevcar, Bojan A1 - Golobic, Amalija A1 - Strauch, Peter T1 - Dynamic pseudo Jahn-Teller distortion in a compressed octahedral CuO6 complex JF - Polyhedron : the international journal of inorganic and organometallic chemistry N2 - The crystal structure of cis-[Cu(C8H7O3)(2)(H2O)(2)] (115 K data) reveals bidentate vanillinate ions coordinated via methoxy and deprotonated hydroxy oxygen atoms and water molecules in a distorted octahedral CuO6 chromophore. A cis orientation of the ligands enables two non-identical O(methoxy)-Cu-O(water) coordination axes (2.354(l) + 2.163(1); 2.151(1) + 2.020(1) angstrom), and the third shortest O(hydroxy)-Cu-O(hydroxy) axis (1.919(1) + 1.914(1) angstrom). This 115 K coordination sphere differs importantly to the one obtained from the 293 K data of the same compound, where two long 0(methoxy)-Cu-O(water) axes are of the same length, and only minor changes at the short 0(hydroxy)-Cu-O(hydroxy) axis are noticed. An axial symmetry of the complex with an inverse g(1.2)(g(perpendicular to)) > g(3)(g(parallel to)) pattern is observed in the temperature range from 298 to 180 K. A further decrease of temperature reveals gradual changes from axial to rhombic symmetry (g(1) > g(2) > g(3)) that is reversible. A mean-square displacement amplitude (MDSA) analysis reveals a disorder in the Cu-O(methoxy) bonds, but not in the other metal-ligand Cu-O(hydroxy) and Cu-O(water) bonds at 293 and 115 K. The disorder is significantly weaker in the 115 K structure. The MSDA analysis and the structural-EPR agreement show vibrational disorder in two coordination axes, due to the cis conformation of the complex with two 0(methoxy)-Cu-O(water) axes. KW - copper KW - vanillin KW - Jahn-Teller distortion KW - MSDA KW - cis KW - EPR Y1 - 2006 U6 - https://doi.org/10.1016/j.poly.2006.04.009 SN - 0277-5387 VL - 25 IS - 15 SP - 2824 EP - 2828 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Fudickar, Werner A1 - Vomdran, Katja A1 - Linker, Torsten T1 - Auxiliary controlled singlet-oxygen ene reactions of cyclohexenes JF - Tetrahedron N2 - The photooxygenation of homochiral cyclohexene ketals, which are easily available from 2-cyclohexenone and L-tartrates, affords hydroperoxides and after reduction the corresponding allylic alcohols in good yields and high regioselectivities. This can be rationalized by electronic repulsions in a perepoxide intermediate and provides evidence for unfavorable 1,3 diaxial interactions with a dioxolane oxygen atom. Only low stereoselectivities were observed, due to the flexibility of the cyclohexene ring. However, the diastereomers could be separated and after cleavage of the auxiliary, 4-hydroxy-2-cyclohexen-1-one was isolated in enantiomerically pure form, which can serve as a building block for natural product synthesis. KW - singlet oxygen KW - auxiliary control KW - regioselectivity KW - stereoselectivity Y1 - 2006 U6 - https://doi.org/10.1016/j.tet.2006.07.104 SN - 0040-4020 VL - 62 IS - 46 SP - 10639 EP - 10646 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Note, Carine A1 - Kosmella, Sabine A1 - Koetz, Joachim T1 - Poly(ethyleneimine) as reducing and stabilizing agent for the formation of gold nanoparticles in w/o microemulsions JF - Colloids and surfaces : an international journal devoted to the principles and applications of colloid and interface science ; A, Physicochemical and engineering aspects N2 - This paper is focused on the use of branched poly(ethyleneimine) (PEI) as reducing as well as stabilizing agent for the formation of gold nanoparticles in different media. The process of nanoparticle formation was investigated, in the absence of any other reducing agents, in microemulsion template phase in comparison to the nucleation process in aqueous polymer solution. On the one hand, it was shown that the polyelectrolyte can be used for the controlled single-step synthesis and stabilization of gold nanoparticles via a nucleation reaction and particles with an average diameter of 7.1 nm can be produced. On the other hand, it was demonstrated that the polymer can also act as reducing and stabilizing agent in much more complex systems, i.e. in water-in-oil (w/o) microemulsion droplets. The reverse microemulsion droplets of the quaternary system sodium dodecylsulfate (SDS)/toluene-pentanol (1:1)/water were successfully used for the synthesis of gold nanoparticles. The polymer, incorporated in the droplets, exhibits reducing properties, adsorbs on the surface of the nanoparticles and prevents their aggregation. Consequently, nanoparticles of 8.6 nm can be redispersed after solvent evaporation without a change of their size. Nevertheless, the polymer acts already as a "template" during the formation of the nanoparticles in water and in microemulsion, so that an additional template effect of the microemulsion is not observed. The particle formation for both methods is checked by means of UV-vis spectroscopy and the particle size and size distribution are investigated via dynamic light scattering and transmission electron microscopy (TEM). (c) 2006 Elsevier B.V. All rights reserved. KW - polyelectrolyte KW - microemulsion KW - gold nanoparticles Y1 - 2006 U6 - https://doi.org/10.1016/j.colsurfa.2006.05.018 SN - 0927-7757 VL - 290 IS - 1-3 SP - 150 EP - 156 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Deeken, Anke A1 - Sobel, Edward A1 - Coutand, Isabelle A1 - Haschke, Michael A1 - Riller, Ulrich A1 - Strecker, Manfred T1 - Development of the southern Eastern Cordillera, NW Argentina, constrained by apatite fission track thermochronology: From early Cretaceous extension to middle Miocene shortening JF - Tectonics N2 - [ 1] For the Puna Plateau and Eastern Cordillera of NW Argentina, the temporal and spatial pattern of deformation and surface uplift remain poorly constrained. Analysis of completely and partially reset apatite fission track samples collected from vertical profiles along an ESE trending transect extending from the plateau interior across the southern Eastern Cordillera at similar to 25 degrees S reveals important constraints on the deformation and exhumation history of this part of the Andes. The data constrain the Neogene Andean development of the Eastern Cordillera as well as rift-related exhumation for some of the sampled locations in the Late Jurassic/Early Cretaceous. An intervening Eocene-Oligocene exhumation episode in the southern Eastern Cordillera was probably related to crustal shortening. Subsequent reburial of the area by Andean foreland basin strata commenced between 30 and 25 Myr. Magnitude and duration of sedimentation, revealed by thermal modeling, differ between the sample locations, pointing to an eastward propagating basin system. In the southern Eastern Cordillera, Andean deformation commenced at 22.5 - 21 Myr, predating both the inferred formation of significant topography by 5 - 7.5 Myr and preservation of sediments in the adjacent Cenozoic basins by 6.5 - 8 Myr. Comparing the calculated structural depth of partially reset samples suggests that newly formed west dipping reverse faults along the former Salta Rift margin accommodated most of the Neogene tectonic movement. Late Cenozoic deformation at the southern Eastern Cordillera began earlier in the west and subsequently propagated eastward. The lateral growth of the orogen is coupled with a foreland basin system developing in front of the range and then becomes subsequently compartmentalized by later emergent topography. Y1 - 2006 U6 - https://doi.org/10.1029/2005TC001894 SN - 0278-7407 VL - 25 IS - 6 PB - Union CY - Washington ER - TY - JOUR A1 - Harutyunyan, Gohar A1 - Schulze, Bert-Wolfgang T1 - The Zaremba problem with singular interfaces as a corner boundary value problem JF - Potential analysis : an international journal devoted to the interactions between potential theory, probability theory, geometry and functional analysis N2 - We study mixed boundary value problems for an elliptic operator A on a manifold X with boundary Y, i.e., Au = f in int X, T (+/-) u = g(+/-) on int Y+/-, where Y is subdivided into subsets Y+/- with an interface Z and boundary conditions T+/- on Y+/- that are Shapiro-Lopatinskij elliptic up to Z from the respective sides. We assume that Z subset of Y is a manifold with conical singularity v. As an example we consider the Zaremba problem, where A is the Laplacian and T- Dirichlet, T+ Neumann conditions. The problem is treated as a corner boundary value problem near v which is the new point and the main difficulty in this paper. Outside v the problem belongs to the edge calculus as is shown in Bull. Sci. Math. ( to appear). With a mixed problem we associate Fredholm operators in weighted corner Sobolev spaces with double weights, under suitable edge conditions along Z {v} of trace and potential type. We construct parametrices within the calculus and establish the regularity of solutions. KW - Zaremba problem KW - corner Sobolev spaces with double weights KW - pseudo-differential boundary value problems Y1 - 2006 U6 - https://doi.org/10.1007/s11118-006-9020-6 SN - 0926-2601 VL - 25 SP - 327 EP - 369 PB - Springer CY - Dordrecht ER - TY - JOUR A1 - Stepanov, Arthur T1 - Robert Frank: Phrase structure composition and syntactic dependencies / rezensiert von Arthur Stepanov JF - Lingua : international review of general linguistics N2 - Rezensiertes Werk: Frank, Robert: Phrase Structure Composition and Syntactic Dependencies. - Cambridge, MA : MIT Press, 2002. - xiv + 326 S. Y1 - 2006 U6 - https://doi.org/10.1016/j.lingua.2005.06.002 SN - 0024-3841 VL - 116 IS - 12 SP - 2259 EP - 2272 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Martinazzo, Rocco A1 - Nest, Mathias A1 - Saalfrank, Peter A1 - Tantardini, Gian Franco T1 - A local coherent-state approximation to system-bath quantum dynamics JF - The journal of chemical physics : bridges a gap between journals of physics and journals of chemistr N2 - A novel quantum method to deal with typical system-bath dynamical problems is introduced. Subsystem discrete variable representation and bath coherent-state sets are used to write down a multiconfigurational expansion of the wave function of the whole system. With the help of the Dirac-Frenkel variational principle, simple equations of motion-a kind of Schrodinger-Langevin equation for the subsystem coupled to (pseudo) classical equations for the bath-are derived. True dissipative dynamics at all times is obtained by coupling the bath to a secondary, classical Ohmic bath, which is modeled by adding a friction coefficient in the derived pseudoclassical bath equations. The resulting equations are then solved for a number of model problems, ranging from tunneling to vibrational relaxation dynamics. Comparison of the results with those of exact, multiconfiguration time-dependent Hartree calculations in systems with up to 80 bath oscillators shows that the proposed method can be very accurate and might be of help in studying realistic problems with very large baths. To this end, its linear scaling behavior with respect to the number of bath degrees of freedom is shown in practice with model calculations using tens of thousands of bath oscillators. Y1 - 2006 U6 - https://doi.org/10.1063/1.2362821 SN - 0021-9606 SN - 1089-7690 VL - 125 IS - 19 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Krylov, Andrey. V. A1 - Adamzig, H. A1 - Walter, A. D. A1 - Loechel, B. A1 - Kurth, E. A1 - Pulz, O. A1 - Szeponik, Jan A1 - Wegerich, Franziska A1 - Lisdat, Fred T1 - Parallel generation and detection of superoxide and hydrogen peroxide in a fluidic chip JF - Sensors and actuators : B, Chemical N2 - A fluidic chip system was developed, which combines a stable generation of superoxide radicals and hydrogen peroxide with their sensorial detection. The generation of both reactive oxygen species was achieved by immobilization of xanthine oxidase on controlled pore glass in a reaction chamber. Antioxidants can be introduced into the fluidic chip system by means of mixing chamber. The detection of both species is based on the amperometric principle using a biosensor chip with two working electrodes. As sensing protein for both electrodes cytochrome c was used. The novel system was designed for the quantification of the antioxidant efficiency of different potential scavengers of the respective reactive species in an aqueous medium. Several model antioxidants such as ascorbic acid or catalase have been tested under flow conditions. KW - biosensor KW - cytochrome c KW - flow system KW - reactive oxygen species KW - antioxidant Y1 - 2006 U6 - https://doi.org/10.1016/j.snb.2005.11.062 SN - 0925-4005 VL - 119 IS - 1 SP - 118 EP - 126 PB - Elsevier CY - Lausanne ER - TY - JOUR A1 - Perrin, Helene A1 - Colombe, Yves A1 - Mercier, Brigitte A1 - Lorent, Vincent A1 - Henkel, Carsten T1 - Diffuse reflection of a Bose-Einstein condensate from a rough evanescent wave mirror JF - Journal of physics : B, Atomic, molecular and optical physics N2 - We present experimental results showing the diffuse reflection of a Bose Einstein condensate from a rough mirror, consisting of a dielectric substrate supporting a blue-detuned evanescent wave. The scattering is anisotropic, more pronounced in the direction of the surface propagation of the evanescent wave. These results agree very well with theoretical predictions. Y1 - 2006 U6 - https://doi.org/10.1088/0953-4075/39/22/009 SN - 0953-4075 VL - 39 SP - 4649 EP - 4658 PB - IOP Publ. CY - Bristol ER - TY - JOUR A1 - Koulakov, Ivan A1 - Sobolev, Stephan Vladimir A1 - Weber, Bernd A1 - Oreshin, Sergey A1 - Wylegalla, Kurt A1 - Hofstetter, Rami T1 - Teleseismic tomography reveals no signature of the Dead Sea Transform in the upper mantle structure JF - Earth and planetary science letters N2 - We present results of a tomographic inversion of teleseismic data recorded at 48 stations of a temporary network which was installed in the area of the Dead Sea Transform (DST) and operated for 1 yr in the framework of the multidisciplinary DESERT Project. The 3366 teleseismic P and PKP phases from 135 events were hand picked and corrected for surface topography and crustal thickness. The inversion shows pronounced low-velocity anomalies in the crust, beneath the DST, which are consistent with recent results from local-source tomography. These anomalies are likely related to the young sediments and fractured rocks in the fault zone. The deeper the retrieved anomalies are quite weak. Most prominent is the high-velocity strip-like anomaly striking SE-NW. We attribute this anomaly to the inherited heterogeneity of lithospheric structure, with a possible contribution by the shallow Precambrian basement east of the DST and to lower crustal heterogeneity reported in this region by other seismic studies. We do not observe reliable signature of the DST in the upper mantle structure. Some weak indications of low-velocity anomalies in the upper mantle beneath the DST may well result from the down-smearing of the strong upper crustal anomalies. We also see very little topography of the lithosphere-asthenosphere boundary beneath the DST, which would generate significant horizontal velocity variations. These results are consistent with predictions from a recent thereto-mechanical model of the DST. Our tomographic model provides some indication of hot mantle flow from the deeper upper mantle rooted in the region of the Red Sea. However, resolution tests show that this anomaly may well be beyond resolution of the model. (c) 2006 Elsevier B.V. All rights reserved. KW - teleseismic tomography KW - Dead Sea Transform KW - lithosphere KW - asthenosphere KW - tectonophysics Y1 - 2006 U6 - https://doi.org/10.1016/j.epsl.2006.09.039 SN - 0012-821X VL - 252 IS - 1-2 SP - 189 EP - 200 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Hausen, Harald A1 - Bleidorn, Christoph T1 - Significance of chaetal arrangement for maldanid systematics (Annelida : Maldanidae) JF - Scientia marina : international journal on marine sciences N2 - Maldanids are usually divided into several subfamilies: Euclymeninae, Lumbriclymeninae, Maldaninae, Nicomachinae, Rhodininae, Clymenurinae, Notoproctinae, and Boguinae. The taxonomy of maldanids and the delimination of these taxa are mainly based on head morphology, total number of segments, chaetal structure, shape of the pygidium, and position of the anus. The maldanid ingroup relationships, as well as the monophyly of the proposed subfamilies, have so far not been investigated. Pilgrim (1977) described a shift of the notopodial chaetal rows from a transverse direction in anterior chaetigers to a more longitudinal one in posterior chaetigers in Clymene torquata (Leidy, 1855) and Euclymene oerstedii (Claparede, 1863), both belonging to the Euclymeninae. We investigated several maldanid species to assess the usefulness of this character for maldanid systematics and used 3D-reconstruction techniques to reveal the complete geometry of the chaetal sacs. Our investigation shows that a shift is apparent in Euclymene, Axiothella, Johnstonia (all Euclymeninae) and Clymenura (Clymenurinae), but absent in species like Maldane sarsi (Malmgren, 1865), Metasychis disparidentata (Moore, 1904) (both Maldaninae) and Petaloproctus borealis Ardwisson, 1906 (Nicomachinae). The shift is not typical for sedentary polychaetes and is apomorphic within maldanid polychaetes. It thus argues for a close relationship between Euclymeninae and Clymenurinae. The investigation of further maldanid species of different subfamilies may shed additional light on maldanid systematics. KW - Annelida KW - Polychaeta KW - Maldanidae KW - systematics KW - chaetae KW - chaetal arrangement Y1 - 2006 SN - 0214-8358 VL - 70 SP - 75 EP - 79 PB - Institut de Ciències del Mar CY - Barcelona ER - TY - JOUR A1 - Meucci, Riccardo A1 - Salvadori, Francesco A1 - Ivanchenko, Mikhail V. A1 - Al Naimee, Kais A1 - Zhou, Chansong A1 - Arecchi, Fortunato Tito A1 - Boccaletti, Stefano A1 - Kurths, Jürgen T1 - Synchronization of spontaneous bursting in a CO2 laser JF - Physical review : E, Statistical, nonlinear and soft matter physics N2 - We present experimental and numerical evidence of synchronization of burst events in two different modulated CO2 lasers. Bursts appear randomly in each laser as trains of large amplitude spikes intercalated by a small amplitude chaotic regime. Experimental data and model show the frequency locking of bursts in a suitable interval of coupling strength. We explain the mechanism of this phenomenon and demonstrate the inhibitory properties of the implemented coupling. Y1 - 2006 U6 - https://doi.org/10.1103/PhysRevE.74.066207 SN - 2470-0045 SN - 2470-0053 VL - 74 PB - American Physical Society CY - College Park ER - TY - JOUR A1 - Zemanova, Lucia A1 - Zhou, Changsong A1 - Kurths, Jürgen T1 - Structural and functional clusters of complex brain networks JF - Physica, D, Nonlinear phenomena N2 - Recent research using the complex network approach has revealed a rich and complicated network topology in the cortical connectivity of mammalian brains. It is of importance to understand the implications of such complex network structures in the functional organization of the brain activities. Here we study this problem from the viewpoint of dynamical complex networks. We investigate synchronization dynamics on the corticocortical network of the cat by modeling each node (cortical area) of the network with a sub-network of interacting excitable neurons. We find that the network displays clustered synchronization behavior, and the dynamical clusters coincide with the topological community structures observed in the anatomical network. Our results provide insights into the relationship between the global organization and the functional specialization of the brain cortex. KW - cortical network KW - anatomical connectivity KW - functional connectivity KW - topological community KW - dynamical cluster Y1 - 2006 U6 - https://doi.org/10.1016/j.physd.2006.09.008 SN - 0167-2789 SN - 1872-8022 VL - 224 IS - 1-2 SP - 202 EP - 212 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Motter, Adilson E. A1 - Matias, Manuel A. A1 - Kurths, Jürgen A1 - Ott, Edward T1 - Dynamics on complex networks and applications T2 - Physica. D, Nonlinear phenomena KW - complex systems KW - nonlinear dynamics KW - statistical physics Y1 - 2006 U6 - https://doi.org/10.1016/j.physd.2006.09.012 SN - 0167-2789 VL - 224 IS - 1-2 SP - VII EP - VIII PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Akpo, Claudia A1 - Weber, Edwin A1 - Reiche, Jürgen T1 - Synthesis, Langmuir and Langmuir-Blodgett film behaviour of new dendritic amphiphiles JF - New journal of chemistry N2 - New amphiphilic compounds 1-9 that feature a construction with dendronized hydrophilic and hydrophobic segment groups connected to a specific aromatic or aliphatic spacer unit have been synthesized, following a modular building block strategy. The hydrophilic dendrons are typically branched elements with peripheral carboxylic groups, unlike the hydrophobic dendrons that contain peripheral alkyl chains as part of respective amide functions. The hydrophilic dendrons are in different generations of branching, while the hydrophobic dendrons are all in the first generation of branching (three terminal branching), but differ in the length of the alkyl chains, thus giving rise to designed structure and amphiphilic properties in the new compounds. The resulting surfactants are capable of forming well-defined Langmuir films of remarkable stability when spread from a solution onto an aqueous subphase. Nevertheless, specific packing behaviour and orientation of the amphiphilic molecules were found, depending on the molecular structure, as determined using analysis of the surface pressure-area (pi-A) isotherms. Langmuir-Blodgett transfer of the first monolayer from a pure water subphase to a clean silicon wafer proved possible for the amphiphiles of peripheral alkyl chain length C-12, while the amphiphiles with the longer alkyl chains failed, possibly due to the more rigid monolayers they form, impeding the transfer. Y1 - 2006 U6 - https://doi.org/10.1039/b609645j SN - 1144-0546 SN - 1369-9261 VL - 30 SP - 1820 EP - 1833 PB - RSC CY - Cambridge ER - TY - JOUR A1 - Stobiecki, Maciej A1 - Skirycz, Aleksandra A1 - Kerhoas, L. A1 - Kachlicki, P. A1 - Muth, D. A1 - Einhorn, J. A1 - Mueller-Roeber, Bernd T1 - Profiling of phenolic glycosidic conjugates in leaves of Arabidopsis thaliana using LC/MS JF - Metabolomics : the official journal of the Metabolomics Society N2 - Profiling of plant secondary metabolites is still a very difficult task. Liquid chromatography (LC) or capillary electrophoresis hyphenated with different kinds of detectors are methods of choice for analysis of polar, thermo labile compounds with high molecular masses. We demonstrate the applicability of LC combined with UV diode array or/and mass spectrometric detectors for the unambiguous identification and quantification of flavonoid conjugates isolated from Arahidopsis thaliana leaves of different genotypes and grown in different environmental conditions. During LC/UV/MS/MS analyses we were able to identify tetra-, tri, and di-glycosides of kaempferol, quercetin and isorhamnetin. Based on our results we can conclude that due to the co-elution of different chemical compounds in reversed phase H PLC systems the application of UV detectors does not allow to precisely profile all flavonoid conjugates existing in A. thaliana genotypes. Using MS detection it was possible to unambiguously recognize the glycosylation patterns of the aglycones. However, from the mass spectra we could not conclude neither the anomeric form of the C-1 carbon atoms of sugar moieties in glycosidic bonds between sugars or sugar and aglycone nor the position of the second carbon involved in disaccharides. The applicability of collision induced dissociation techniques (CID MS/MS) for structural analyses of the studied group of plant secondary metabolites with two types of analyzers (triple quadrupole or ion trap) was demonstrated. KW - liquid chromatography-mass spectrometry KW - metabolite profiling KW - metabolomics KW - flavonoid glycosides Y1 - 2006 U6 - https://doi.org/10.1007/s11306-006-0031-5 SN - 1573-3882 VL - 2 SP - 197 EP - 219 PB - Springer CY - New York ER - TY - JOUR A1 - Stepanov, Arthur A1 - Stateva, Penka T1 - Successive cyclicity as residual wh-scope marking JF - Lingua : international review of general linguistics KW - wh-scope marker KW - long distance wh-movement KW - incorporation KW - indirect dependency KW - complementation Y1 - 2006 U6 - https://doi.org/10.1016/j.lingua.2005.06.004 SN - 0024-3841 VL - 116 IS - 12 SP - 2107 EP - 2153 PB - Elsevier CY - Amsterdam ER - TY - JOUR A1 - Vasishth, Shravan A1 - Lewis, Richard L. T1 - Argument-head distance and processing complexity: Explaining both locality and antilocality effects JF - Language : journal of the Linguistic Society of America N2 - Although proximity between arguments and verbs (locality) is a relatively robust determinant of sentence-processing difficulty (Hawkins 1998, 2001, Gibson 2000), increasing argument-verb distance can also facilitate processing (Konieczny 2000). We present two self-paced reading (SPR) experiments involving Hindi that provide further evidence of antilocality, and a third SPR experiment which suggests that similarity-based interference can attenuate this distance-based facilitation. A unified explanation of interference, locality, and antilocality effects is proposed via an independently motivated theory of activation decay and retrieval interference (Anderson et al. 2004).* Y1 - 2006 U6 - https://doi.org/10.1353/lan.2006.0236 SN - 0097-8507 VL - 82 IS - 4 SP - 767 EP - 794 PB - Linguistic Society of America CY - Washington ER - TY - JOUR A1 - Schmidt, Bernd A1 - Staude, Lucia T1 - Unexpected transfer hydrogenation of C-C-double bonds during Tandem-RCM-isomerization reactions JF - Journal of organometallic chemistry N2 - Unexpected hydrogen transfer from 2-propanol to C-C-double bonds has been observed in the course of a Tandem RCM-isomerization reaction leading to sterically congested spirocycles. KW - ruthenium KW - metathesis KW - isomerization KW - hydrogenation KW - transferhydrogenation KW - tandem sequence Y1 - 2006 U6 - https://doi.org/10.1016/j.jorganchem.2006.07.011 SN - 0022-328X VL - 691 IS - 24-25 SP - 5218 EP - 5221 PB - Elsevier CY - Lausanne ER - TY - JOUR A1 - Holschneider, Matthias A1 - Teschke, Gerd T1 - Existence and computation of optimally localized coherent states JF - Journal of mathematical physics N2 - This paper is concerned with localization properties of coherent states. Instead of classical uncertainty relations we consider "generalized" localization quantities. This is done by introducing measures on the reproducing kernel. In this context we may prove the existence of optimally localized states. Moreover, we provide a numerical scheme for deriving them. Y1 - 2006 U6 - https://doi.org/10.1063/1.2375031 SN - 0022-2488 SN - 1089-7658 VL - 47 IS - 3 SP - 211 EP - 214 PB - Elsevier CY - Melville ER - TY - JOUR A1 - Gosson, Maurice A. de A1 - Gosson, Serge M. de T1 - Extension of the Conley-Zehnder index, a product formula, and an application to the Weyl representation of metaplectic operators JF - Journal of mathematical physics N2 - The aim of this paper is to express the Conley-Zehnder index of a symplectic path in terms of an index due to Leray and which has been studied by one of us in a previous work. This will allow us to prove a formula for the Conley-Zehnder index of the product of two symplectic paths in terms of a symplectic Cayley transform. We apply our results to a rigorous study of the Weyl representation of metaplectic operators, which plays a crucial role in the understanding of semiclassical quantization of Hamiltonian systems exhibiting chaotic behavior. Y1 - 2006 U6 - https://doi.org/10.1063/1.239066 SN - 0022-2488 VL - 47 IS - 12 PB - American Institute of Physics CY - Melville ER - TY - JOUR A1 - Gil, Juan B. A1 - Krainer, Thomas A1 - Mendoza, Gerardo A. T1 - Resolvents of elliptic cone operators JF - Journal of functional analysis N2 - We prove the existence of sectors of minimal growth for general closed extensions of elliptic cone operators under natural ellipticity conditions. This is achieved by the construction of a suitable parametrix and reduction to the boundary. Special attention is devoted to the clarification of the analytic structure of the resolvent. KW - resolvents KW - manifolds with conical singularities KW - spectral theory KW - parametrices KW - boundary value problems Y1 - 2006 U6 - https://doi.org/10.1016/j.jfa.2006.07.010 SN - 0022-1236 VL - 241 IS - 1 SP - 1 EP - 55 PB - Elsevier CY - San Diego ER - TY - JOUR A1 - Boeniger, Urs A1 - Tronicke, Jens A1 - Holliger, Klaus A1 - Becht, Andreas T1 - Multi-offset vertical radar profiling for subsurface reflection imaging JF - Journal of environmental & engineering geophysics : JEEG N2 - The vertical radar profiling (VRP) technique uses surface-to-borehole acquisition geometries comparable to vertical seismic profiling (VSP). Major differences between the two methods do arise due to the fundamentally differing nature of the velocity-depth gradients and transmitter/receiver directivities. Largely for this reason, VRP studies have so far essentially been limited to the reconstruction of velocity-depth profiles by inverting direct arrival times from single-offset VRP surveys. In this study, we investigate the potential to produce high-resolution subsurface reflection images from multi-offset VRP data. Two synthetic data sets are used to evaluate a processing strategy suitably adapted from VSP processing. Despite the fundamental differences between VRP and VSP data, we found that our processing approach is capable of reconstructing subsurface structures of comparable complexity to those routinely imaged by VSP data. Finally, we apply our processing flow to two multi-offset VRP data sets recorded at a well constrained hydrogeophysical test site in SW-Germany. The inferred VRP images are compared with high-quality surface georadar reflection images and lithological logs available at the borehole locations. We find that the VRP images are in good agreement with the surface georadar data and reliably detect the major lithological boundaries. Due to the significantly shorter ray-paths, the depth penetration of the VRP data is, however, considerably higher than that of the surface georadar data. VRP reflection images thus provide an effective means for the depth-calibration and extension of conventional surface georadar data in the vicinity of boreholes. Y1 - 2006 U6 - https://doi.org/10.2113/JEEG11.4.289 SN - 1083-1363 VL - 11 IS - 4 SP - 289 EP - 298 PB - EEGS CY - Denver ER - TY - JOUR A1 - Heringer-Walther, Silvia A1 - Moreira, Maria da Consolacao V. A1 - Wessel, Niels A1 - Wang, Yong A1 - Ventura, Pago Moreira A1 - Schultheiss, Heinz-Peter A1 - Walther, Thomas T1 - Does the C-type natriuretic peptide have prognostic value in Chagas disease and other dilated cardiomyopathies JF - Journal of cardiovascular pharmacology N2 - Atrial natriuretic peptides (ANP) and brain natriuretic peptides (BNP) are powerful neurohormonal indicators of left-ventricular function and prognosis in heart failure (HF). Chagas disease (CD) caused by the protozoan Trypanosoma cruzi. remains a major cause of HF in Latin America. We assessed whether the plasma concentration of the third natriuretic peptide, C-type natnuretic peptide (CNP), also has diagnostic and prognostic properties in patients with CD or other dilated cardiomyopathies (DCM). Blood samples were obtained from 66 patients with CD, 50 patients with DCM from other causes, and 30 gender- and age-matched healthy subjects. Patients were subdivided according to the New York Heart Association (NYHA) class. The CNP concentration was determined by radioimmunoassay (Immundiagnostik, Bensheim, Germany). The main duration of follow-up was 31.4 months (range 13 to 54 months), 19 patients had died and 11 patients received a heart transplant. CNP concentrations were only significantly altered in patients with DCM or CD of the NYHA classes III and IV (P < 0.05). The Pearson correlation of echocardiographic data with CNP revealed an association only with the left-ventricular end systolic volume (P = 0.03) in patients with DCM. Furthermore, CNP did not predict mortality or the necessity for heart transplant. Our data are the first to demonstrate the raised levels of the third natriuretic peptide CNP in CD and other DCM Whereas ANP and BNP have a high predictive value for mortality in both diseases, CNP is without any predictive potency. KW - cardiomyopathy KW - heart failure KW - natriuretic peptide system KW - Trypanosoma cruzi Y1 - 2006 U6 - https://doi.org/10.1097/01.fjc.0000249892.22635.46 SN - 0160-2446 VL - 48 IS - 6 SP - 293 EP - 298 PB - Lippincott Williams & Wilkins CY - Philadelphia ER - TY - JOUR A1 - Gessner, Jörn A1 - Arndt, Gerd-Michael A1 - Tiedemann, Ralph A1 - Bartel, Ryszard A1 - Kirschbaum, Frank T1 - Remediation measures for the Baltic sturgeon: status review and perspectives JF - Journal of applied ichthyology N2 - More than one century ago, sturgeons were prevalent species in the fish communities of all major German rivers both in the North and the Baltic seas drainages. Since then, the populations declined rapidly due to river damming, overfishing and pollution. The last sturgeon catches in the Baltic drainage system occurred during the late 1960ies. Only a few individual captures have been reported during the last 30 years with the most recent records in the Lake Ladoga ( Russia), where the last confirmed catch was recorded in 1984, and a single individual caught off Estonia in 1996. Today, sturgeons are considered missing or extinct in German waters. First attempts for remediation of the species were undertaken in the mid 1990ies. Subsequently, phylogenetic and population genetic analyses of the species were carried out using mtDNA, microsatellites, and nuclear markers ( SNPs). These genetic analyses using recent and historic material have proven the existence of two different species in the Baltic Sea in what was previously considered to represent the European Atlantic sturgeon only. In the Baltic Sea, the American Atlantic sturgeon ( A. oxyrinchus) succeeded to colonize this brackish water system during the Middle Ages. In the North Sea, the European Atlantic sturgeon ( A. sturio) is considered to be the endemic species. These results led to the separation of the remediation activities in the North Sea and the Baltic Sea tributaries. Further studies on the mechanism that lead to the extinction of A. sturio in Germany and the subsequent succession of the A. oxyrinchus mtDNA haplotype are currently been carried out. Broodstock development using the northernmost populations of A. oxyrinchus is currently under way. As a further prerequisite to re-introduce this species into the Baltic, the evaluation of the status of critical habitats for the early life stages of the American Atlantic sturgeon in the River Odra has been performed in collaboration with the Institute for Inland Fisheries of Poland. Alternative fisheries techniques, based on the data of by-catch of exotic sturgeons in the fishery, are presently developed in close cooperation with the fishery to reduce fisheries related mortality in juvenile sturgeons upon release. Monitoring of habitat utilization and migration characteristics of juvenile fish upon experimental release will have to be carried out shortly, using acoustic telemetry, with the aim to follow the fate of the released fish and to determine the best time-size-release-window for future release programmes. Y1 - 2007 U6 - https://doi.org/10.1111/j.1439-0426.2007.00925.x SN - 0175-8659 VL - 22 IS - S1 SP - 23 EP - 31 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Iryu, Yasufumi A1 - Matsuda, Hiroki A1 - Machiyama, Hideaki A1 - Piller, Werner E. A1 - Quinn, Terrence M. A1 - Mutti, Maria T1 - Introductory perspective on the COREF project JF - The island arc : official journal of the Geological Society of Japan N2 - Coral reefs are tropic to subtropic, coastal ecosystems comprising very diverse organisms. Late Quaternary reef deposits are fossil archives of environmental, tectonic and eustatic variations that can be used to reconstruct the paleoclimatic and paleoceano-graphic history of the tropic surface oceans. Reefs located at the latitudinal limits of coral-reef ecosystems (i.e. those at coral-reef fronts) are particularly sensitive to environmental changes-especially those associated with glacial-interglacial changes in climate and sealevel. We propose a land and ocean scientific drilling campaign in the Ryukyu Islands (the Ryukyus) in the northwestern Pacific Ocean to investigate the dynamic response of the corals and coral-reef ecosystems in this region to Late Quaternary climate and sealevel change. Such a drilling campaign, which we call the COREF (coral-reef front) Project, will allow the following three major questions to be evaluated: (i) What are the nature, magnitude and driving mechanisms of coral-reef front migration in the Ryukyus? (ii) What is the ecosystem response of coral reefs in the Ryukyus to Quaternary climate changes? (iii) What is the role of coral reefs in the global carbon cycle? Subsidiary objectives include (i) the timing of coral-reef initiation in the Ryukyus and its causes; (ii) the position of the Kuroshio current during glacial periods and its effects on coral-reef formation; and (iii) early carbonate diagenetic responses as a function of compounded variations in climate, eustacy and depositional mineralogies (subtropic aragonitic to warm-temperate calcitic). The geographic, climatic and oceanographic settings of the Ryukyu Islands provide an ideal natural laboratory to address each of these research questions. KW - coral KW - Integrated Ocean Drilling Program KW - International Continental Scientific Drilling Program KW - limestone KW - Quaternary KW - reef KW - Ryukyu Group KW - Ryukyu Islands KW - sealevel Y1 - 2006 U6 - https://doi.org/10.1111/j.1440-1738.2006.00537.x SN - 1038-4871 VL - 15 IS - 4 SP - 393 EP - 406 PB - Wiley-Blackwell CY - Oxford ER - TY - JOUR A1 - Reichard, Christoph T1 - Strengthening competitiveness of local public service providers in Germany JF - International review of administrative sciences : an international journal of comparative public administration N2 - This article discusses the challenges for providers of local public services to adapt to increasing marketization and competition in the public sector. Based on some empirical evidence from local government in Germany, the article describes different adaptive measures in the past and shows the legal restrictions to strengthening performance and particularly competitiveness. Furthermore, the article presents some findings from good practice cases of local service providers in Germany who have successfully exposed themselves to market mechanisms. Finally, the article discusses observed results of increased competitiveness in the local government sector, with special regard to quality, efficiency and public employment. The article concludes with describing necessary elements of a competitive regime for public services and with some general reflections about the role of competition in the public sector. KW - competition KW - competitiveness KW - contractor/provider split KW - ensuring state KW - marketization KW - service provider strategies Y1 - 2006 U6 - https://doi.org/10.1177/0020852306070079 SN - 0020-8523 VL - 72 IS - 4 SP - 473 EP - 492 PB - Sage CY - London ER -