TY  - GEN
A1  - Konigorski, Stefan
A1  - Wernicke, Sarah
A1  - Slosarek, Tamara
A1  - Zenner, Alexander Maximilian
A1  - Strelow, Nils
A1  - Ruether, Darius Ferenc
A1  - Henschel, Florian
A1  - Manaswini, Manisha
A1  - Pottbäcker, Fabian
A1  - Edelman, Jonathan Antonio
A1  - Owoyele, Babajide
A1  - Danieletto, Matteo
A1  - Golden, Eddye
A1  - Zweig, Micol
A1  - Nadkarni, Girish N.
A1  - Bottinger, Erwin
T1  - StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials
T2  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät
N2  - N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.
T3  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 12 
KW  - digital interventions
KW  - N-of-1 trial
KW  - SCED
KW  - single-case experimental design
KW  - web application
KW  - mobile application
KW  - app
KW  - digital health
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-580370
IS  - 12
ER  - 
TY  - GEN
A1  - Wernicke, Sarah
A1  - De Witt Huberts, Jessie
A1  - Wippert, Pia-Maria
T1  - The pain of being misunderstood
BT  - invalidation of pain complaints in chronic low back pain patients
T2  - Postprints der Universität Potsdam : Humanwissenschaftliche Reihe
N2  - A particular form of social pain is invalidation. Therefore, this study (a) investigates whether patients with chronic low back pain experience invalidation, (b) if it has an influence on their pain, and (c) explores whether various social sources (e.g. partner and work) influence physical pain differentially. A total of 92 patients completed questionnaires, and for analysis, Pearson's correlation coefficients and hierarchical linear regression analyses were conducted. They indicated a significant association between discounting and disability due to pain (respective =.29, p>.05). Especially, discounting by partner was linked to higher disability (=.28, p>.05).
T3  - Zweitveröffentlichungen der Universität Potsdam : Humanwissenschaftliche Reihe - 403 
KW  - chronic low back pain
KW  - disability
KW  - invalidation
KW  - social pain
KW  - social rejection
Y1  - 2018
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-404864
IS  - 403
ER  -