TY  - GEN
A1  - Konigorski, Stefan
A1  - Wernicke, Sarah
A1  - Slosarek, Tamara
A1  - Zenner, Alexander Maximilian
A1  - Strelow, Nils
A1  - Ruether, Darius Ferenc
A1  - Henschel, Florian
A1  - Manaswini, Manisha
A1  - Pottbäcker, Fabian
A1  - Edelman, Jonathan Antonio
A1  - Owoyele, Babajide
A1  - Danieletto, Matteo
A1  - Golden, Eddye
A1  - Zweig, Micol
A1  - Nadkarni, Girish N.
A1  - Bottinger, Erwin
T1  - StudyU: A Platform for Designing and Conducting Innovative Digital N-of-1 Trials
T2  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät
N2  - N-of-1 trials are the gold standard study design to evaluate individual treatment effects and derive personalized treatment strategies. Digital tools have the potential to initiate a new era of N-of-1 trials in terms of scale and scope, but fully functional platforms are not yet available. Here, we present the open source StudyU platform, which includes the StudyU Designer and StudyU app. With the StudyU Designer, scientists are given a collaborative web application to digitally specify, publish, and conduct N-of-1 trials. The StudyU app is a smartphone app with innovative user-centric elements for participants to partake in trials published through the StudyU Designer to assess the effects of different interventions on their health. Thereby, the StudyU platform allows clinicians and researchers worldwide to easily design and conduct digital N-of-1 trials in a safe manner. We envision that StudyU can change the landscape of personalized treatments both for patients and healthy individuals, democratize and personalize evidence generation for self-optimization and medicine, and can be integrated in clinical practice.
T3  - Zweitveröffentlichungen der Universität Potsdam : Reihe der Digital Engineering Fakultät - 12 
KW  - digital interventions
KW  - N-of-1 trial
KW  - SCED
KW  - single-case experimental design
KW  - web application
KW  - mobile application
KW  - app
KW  - digital health
Y1  - 2023
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-580370
IS  - 12
ER  -