TY  - GEN
A1  - Zurell, Damaris
A1  - Elith, Jane
A1  - Schröder-Esselbach, Boris
T1  - Predicting to new environments  tools for visualizing model behaviour and impacts on mapped distributions
T2  - Diversity & distributions : a journal of biological invasions and biodiversity
N2  - Data limitations can lead to unrealistic fits of predictive species distribution models (SDMs) and spurious extrapolation to novel environments. Here, we want to draw attention to novel combinations of environmental predictors that are within the sampled range of individual predictors but are nevertheless outside the sample space. These tend to be overlooked when visualizing model behaviour. They may be a cause of differing model transferability and environmental change predictions between methods, a problem described in some studies but generally not well understood. We here use a simple simulated data example to illustrate the problem and provide new and complementary visualization techniques to explore model behaviour and predictions to novel environments. We then apply these in a more complex real-world example. Our results underscore the necessity of scrutinizing model fits, ecological theory and environmental novelty.
KW  - Environmental niche
KW  - extrapolation
KW  - inflated response curves
KW  - novel environment
KW  - sampling space
KW  - species distribution models
Y1  - 2012
U6  - https://doi.org/10.1111/j.1472-4642.2012.00887.x
SN  - 1366-9516
VL  - 18
IS  - 6
SP  - 628
EP  - 634
PB  - Wiley-Blackwell
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Zhang, Yunming
A1  - Lenhard, Michael
T1  - Exiting Already? Molecular Control of Cell-Proliferation Arrest in Leaves: Cutting Edge
T2  - Molecular plant
Y1  - 2017
U6  - https://doi.org/10.1016/j.molp.2017.05.004
SN  - 1674-2052
SN  - 1752-9867
VL  - 10
SP  - 909
EP  - 911
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Xiang, Hai
A1  - Hofreiter, Michael
A1  - Zhao, Xingbo
T1  - Reply to Peng et al.: Archaeological contexts should not be ignored for early chicken domestication
T2  - Proceedings of the National Academy of Sciences of the United States of America
Y1  - 2015
U6  - https://doi.org/10.1073/pnas.1502207112
SN  - 0027-8424
VL  - 112
IS  - 16
SP  - E1972
EP  - E1973
PB  - National Acad. of Sciences
CY  - Washington
ER  - 
TY  - GEN
A1  - Xiang, Hai
A1  - Gao, Jianqiang
A1  - Yu, Baoquan
A1  - Hofreiter, Michael
A1  - Zhao, Xingbo
T1  - Reply to Peters et al.: Further discussions confirm early Holocene chicken domestication in northern China
T2  - Proceedings of the National Academy of Sciences of the United States of America
Y1  - 2015
U6  - https://doi.org/10.1073/pnas.1503956112
SN  - 0027-8424
VL  - 112
IS  - 19
SP  - E2416
EP  - E2416
PB  - National Acad. of Sciences
CY  - Washington
ER  - 
TY  - GEN
A1  - Xenikoudakis, Georgios
A1  - Ahmed, Mayeesha
A1  - Harris, Jacob Colt
A1  - Wadleigh, Rachel
A1  - Paijmans, Johanna L. A.
A1  - Hartmann, Stefanie
A1  - Barlow, Axel
A1  - Lerner, Heather
A1  - Hofreiter, Michael
T1  - Ancient DNA reveals twenty million years of aquatic life in beavers
T2  - Current biology : CB
N2  - Xenikoudakis et al. report a partial mitochondrial genome of the extinct giant beaver Castoroides and estimate the origin of aquatic behavior in beavers to approximately 20 million years. This time estimate coincides with the extinction of terrestrial beavers and raises the question whether the two events had a common cause.
Y1  - 2020
U6  - https://doi.org/10.1016/j.cub.2019.12.041
SN  - 0960-9822
SN  - 1879-0445
VL  - 30
IS  - 3
SP  - R110
EP  - R111
PB  - Current Biology Ltd.
CY  - London
ER  - 
TY  - GEN
A1  - Wutke, Saskia
A1  - Andersson, Leif
A1  - Benecke, Norbert
A1  - Sandoval-Castellanos, Edson
A1  - Gonzalez, Javier
A1  - Hallsson, Jon Hallsteinn
A1  - Lougas, Lembi
A1  - Magnell, Ola
A1  - Morales-Muniz, Arturo
A1  - Orlando, Ludovic
A1  - Palsdottir, Albina Hulda
A1  - Reissmann, Monika
A1  - Munoz-Rodriguez, Mariana B.
A1  - Ruttkay, Matej
A1  - Trinks, Alexandra
A1  - Hofreiter, Michael
A1  - Ludwig, Arne
T1  - The origin of ambling horses
T2  - Current biology
N2  - Horseback riding is the most fundamental use of domestic horses and has had a huge influence on the development of human societies for millennia. Over time, riding techniques and the style of riding improved. Therefore, horses with the ability to perform comfortable gaits (e.g. ambling or pacing), so-called ‘gaited’ horses, have been highly valued by humans, especially for long distance travel. Recently, the causative mutation for gaitedness in horses has been linked to a substitution causing a premature stop codon in the DMRT3 gene (DMRT3_Ser301STOP) [1]. In mice, Dmrt3 is expressed in spinal cord interneurons and plays an important role in the development of limb movement coordination [1]. Genotyping the position in 4396 modern horses from 141 breeds revealed that nowadays the mutated allele is distributed worldwide with an especially high frequency in gaited horses and breeds used for harness racing [2]. Here, we examine historic horse remains for the DMRT3 SNP, tracking the origin of gaitedness to Medieval England between 850 and 900 AD. The presence of the corresponding allele in Icelandic horses (9th–11th century) strongly suggests that ambling horses were brought from the British Isles to Iceland by Norse people. Considering the high frequency of the ambling allele in early Icelandic horses, we believe that Norse settlers selected for this comfortable mode of horse riding soon after arrival. The absence of the allele in samples from continental Europe (including Scandinavia) at this time implies that ambling horses may have spread from Iceland and maybe also the British Isles across the continent at a later date.
Y1  - 2016
U6  - https://doi.org/10.1016/j.cub.2016.07.001
SN  - 0960-9822
SN  - 1879-0445
VL  - 26
SP  - R697
EP  - R699
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Wiegmann, Alex
A1  - Rutschmann, Ronja
A1  - Willemsen, Pascale
T1  - Correction to: Empirically Investigating the Concept of Lying (vol 34, pg 591, 2017)
T2  - Journal of Indian Council of Philosophical Research
Y1  - 2018
U6  - https://doi.org/10.1007/s40961-017-0123-9
SN  - 0970-7794
SN  - 2363-9962
VL  - 35
IS  - 1
SP  - 223
EP  - 223
PB  - Springer
CY  - New Dehli
ER  - 
TY  - GEN
A1  - Weisser, Karin
A1  - Stübler, Sabine
A1  - Matheis, Walter
A1  - Huisinga, Wilhelm
T1  - Towards toxicokinetic modelling of aluminium exposure from adjuvants in medicinal products
T2  - Regulatory toxicology and pharmacology : official journal of the International Society for Regulatory Toxicology and Pharmacology
N2  - As a potentially toxic agent on nervous system and bone, the safety of aluminium exposure from adjuvants in vaccines and subcutaneous immune therapy (SCIT) products has to be continuously reevaluated, especially regarding concomitant administrations. For this purpose, knowledge on absorption and disposition of aluminium in plasma and tissues is essential. Pharmacokinetic data after vaccination in humans, however, are not available, and for methodological and ethical reasons difficult to obtain. To overcome these limitations, we discuss the possibility of an in vitro-in silico approach combining a toxicokinetic model for aluminium disposition with biorelevant kinetic absorption parameters from adjuvants. We critically review available kinetic aluminium-26 data for model building and, on the basis of a reparameterized toxicokinetic model (Nolte et al., 2001), we identify main modelling gaps. The potential of in vitro dissolution experiments for the prediction of intramuscular absorption kinetics of aluminium after vaccination is explored. It becomes apparent that there is need for detailed in vitro dissolution and in vivo absorption data to establish an in vitro-in vivo correlation (IVIVC) for aluminium adjuvants. We conclude that a combination of new experimental data and further refinement of the Nolte model has the potential to fill a gap in aluminium risk assessment. (C) 2017 Elsevier Inc. All rights reserved.
KW  - Aluminium
KW  - Aluminium adjuvants
KW  - Absorption kinetics
KW  - Toxicokinetic modelling
KW  - In vitro dissolution
Y1  - 2017
U6  - https://doi.org/10.1016/j.yrtph.2017.02.018
SN  - 0273-2300
SN  - 1096-0295
VL  - 88
SP  - 310
EP  - 321
PB  - Elsevier
CY  - San Diego
ER  - 
TY  - GEN
A1  - Tiedemann, Ralph
A1  - Pfautsch, Simone
T1  - MHC evolution in ducks and allies
T2  - Journal of ornithology
Y1  - 2006
SN  - 0021-8375
VL  - 147
IS  - Supplement 1
SP  - 48
EP  - 48
PB  - Blackwell
CY  - New York
ER  - 
TY  - GEN
A1  - Ten Freyhaus, Henrik
A1  - Huntgeburth, Michael
A1  - Wingler, Kirstin
A1  - Baeumer, A. T.
A1  - Wartenberg, Maria
A1  - Sauer, H.
A1  - Bekhite, Mohamed M.
A1  - Rosenkranz, S.
T1  - Inhibition of ROS liberation by the novel nox inhibitor VAS2870 attenuates PDGF-dependent src activation and chemotaxis, but not proliferation in vascular smooth muscle cells
T2  - European heart journal
Y1  - 2006
SN  - 0195-668X
SN  - 1522-9645
VL  - 27
SP  - 965
EP  - 965
PB  - Oxford University Press
CY  - Oxford
ER  - 
TY  - GEN
A1  - Synodinos, Alexios D.
A1  - Eldridge, David
A1  - Geißler, Katja
A1  - Jeltsch, Florian
A1  - Lohmann, Dirk
A1  - Midgley, Guy
A1  - Blaum, Niels
T1  - Remotely sensed canopy height reveals three pantropical ecosystem states
BT  - a comment
T2  - Ecology : a publication of the Ecological Society of America
Y1  - 2017
U6  - https://doi.org/10.1002/ecy.1997
SN  - 0012-9658
SN  - 1939-9170
VL  - 99
IS  - 1
SP  - 231
EP  - 234
PB  - Wiley
CY  - Hoboken
ER  - 
TY  - GEN
A1  - Stanke, S.
A1  - Wenger, C.
A1  - Bier, Frank Fabian
A1  - Hölzel, Ralph
T1  - Dielectrophoretic functionalization of nanoelectrode arrays for the detection of influenza viruses
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S337
EP  - S337
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Sowemimo, Oluwakemi
A1  - Borcherds, Wade
A1  - Knox-Brown, Patrick
A1  - Rindfleisch, Tobias
A1  - Thalhammer, Anja
A1  - Daughdrill, Gary
T1  - Evolution of Transient Helicity and Disorder in Late Embryogenesis Abundant Protein COR15A
T2  - Biophysical journal
N2  - Cold regulated protein 15A (COR15A) is a nuclear encoded, intrinsically disordered protein that is found in Arabidopsis thaliana. It belongs to the Late Embryogenesis Abundant (LEA) family of proteins and is responsible for increased freezing tolerance in plants. COR15A is intrinsically disordered in dilute solutions and adopts a helical structure upon dehydration or in the presence of co-solutes such as TFE and ethylene glycol. This helical structure is thought to be important for protecting plants from dehydration induced by freezing. Multiple protein sequence alignments revealed the presence of several conserved glycine residues that we hypothesize keeps COR15A from becoming helical in dilute solutions. Using AGADIR, the change in helical content of COR15A when these conserved glycine residues were mutated to alanine residues was predicted. Based on the predictions, glycine to alanine mutants were made at position 68, and 54,68,81, and 84. Labeled samples of wildtype COR15A and mutant proteins were purified and NMR experiments were performed to examine any structural changes induced by the mutations. To test the effects of dehydration on the structure of COR15A, trifluoroethanol, an alcohol based co solvent that is proposed to induce/stabilize helical structure in peptides was added to the NMR samples, and the results of the experiment showed an increase in helical content, compared to the samples without TFE. To test the functional differences between wild type and the mutants, liposome leakage assays were performed. The results from these assays suggest the more helical mutants may augment membrane stability.
Y1  - 2019
U6  - https://doi.org/10.1016/j.bpj.2018.11.2553
SN  - 0006-3495
SN  - 1542-0086
VL  - 116
IS  - 3
SP  - 473A
EP  - 473A
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Sicard, Adrien
A1  - Lenhard, Michael
T1  - Capsella
T2  - Current biology
Y1  - 2018
U6  - https://doi.org/10.1016/j.cub.2018.06.033
SN  - 0960-9822
SN  - 1879-0445
VL  - 28
IS  - 17
SP  - R920
EP  - R921
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Seyfried, Salim
A1  - Rödel, Claudia Jasmin
T1  - Blood flow matters in a zebrafish model of cerebral cavernous malformations
T2  - Circulation research : an official journal of the American Heart Association
Y1  - 2020
U6  - https://doi.org/10.1161/CIRCRESAHA.119.316286
SN  - 0009-7330
SN  - 1524-4571
VL  - 126
IS  - 1
SP  - E1
EP  - E2
PB  - Lippincott Williams & Wilkins
CY  - Baltimore, Md.
ER  - 
TY  - GEN
A1  - Schurr, Frank Martin
A1  - Esler, Karen J.
A1  - Slingsby, Jasper A.
A1  - Allsopp, Nicky
T1  - Fynbos proteaceae as model organisms for biodiversity research and conservation
T2  - South African journal of science
Y1  - 2012
U6  - https://doi.org/10.4102/sajs.v108i11/12.1446
SN  - 0038-2353
VL  - 108
IS  - 11-12
SP  - 10
EP  - 13
PB  - Academy of Science of South Africa
CY  - Lynwood Ridge
ER  - 
TY  - GEN
A1  - Schmoll, Tim
A1  - Schurr, Frank Martin
A1  - Winkel, W.
A1  - Lubjuhn, Thomas
T1  - Female extra-pair mating, fitness and genetic diversity: Expression in socially monogamous Coal Tits
T2  - Journal of ornithology
Y1  - 2006
SN  - 0021-8375
VL  - 147
SP  - 248
EP  - 248
PB  - Elsevier
CY  - New York
ER  - 
TY  - GEN
A1  - Scheller, Frieder W.
A1  - Sakar Dasdan, Dolunay
T1  - Selected papers presented on the 2nd International Conference on the New Trends in Chemistry, Zagreb, Croatia, April 19-22, 2016 Preface
T2  - Bulgarian chemical communications : journal of the Chemical Institutes of the Bulgarian Academy of Sciences and of the Bulgarian Chemical Society = Izvestija po chimija
Y1  - 2016
SN  - 0324-1130
VL  - 48
SP  - 4
EP  - 4
PB  - Bulgarian Academy of Sciences
CY  - Sofia
ER  - 
TY  - GEN
A1  - Scheffler, Tatjana
T1  - Root infinitives on Twitter
T2  - Snippets
Y1  - 2017
U6  - https://doi.org/10.7358/snip-2017-031-sche
SN  - 1590-1807
IS  - 31
SP  - 24
EP  - 25
PB  - Editioni Università di Lettere Economica Diritto
CY  - Milano
ER  - 
TY  - GEN
A1  - Sammler, Svenja
A1  - Ketmaier, Valerio
A1  - Havenstein, Katja
A1  - Tiedemann, Ralph
T1  - Intraspecific rearrangement of duplicated mitochondrial control regions in the luzon tarictic hornbill penelopides manillae (Aves: Bucerotidae)
T2  - Journal of molecular evolution
N2  - Philippine hornbills of the genera Aceros and Penelopides (Bucerotidae) are known to possess a large tandemly duplicated fragment in their mitochondrial genome, whose paralogous parts largely evolve in concert. In the present study, we surveyed the two distinguishable duplicated control regions in several individuals of the Luzon Tarictic Hornbill Penelopides manillae, compare their characteristics within and across individuals, and report on an intraspecific mitochondrial gene rearrangement found in one single specimen, i.e., an interchange between the two control regions. To our knowledge, this is the first observation of two distinct mitochondrial genome rearrangements within a bird species. We briefly discuss a possible evolutionary mechanism responsible for this pattern, and highlight potential implications for the application of control region sequences as a marker in population genetics and phylogeography.
KW  - Bucerotidae
KW  - Concerted evolution
KW  - Control region
KW  - Mitochondrial gene order
KW  - Mitochondrial recombination
KW  - Philippine archipelago
Y1  - 2013
U6  - https://doi.org/10.1007/s00239-013-9591-y
SN  - 0022-2844
SN  - 1432-1432
VL  - 77
IS  - 5-6
SP  - 199
EP  - 205
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Rud, R.
A1  - Käthner, Jana
A1  - Giesser, J.
A1  - Pasche, R.
A1  - Giebel, Antje
A1  - Selbeck, Jörn
A1  - Shenderey, C.
A1  - Fleury, D.
A1  - Zude-Sasse, Manuela
A1  - Alchanatis, Victor
T1  - Monitoring spatial variability in an apple orchard under different water regimes
T2  - International Symposium on Sensing Plant Water Status - Methods and Applications in Horticultural Science
N2  - Precision fruticulture addresses site or tree-adapted crop management. In the present study, soil and tree status, as well as fruit quality at harvest were analysed in a commercial apple (Malus × domestica 'Gala Brookfield'/Pajam1) orchard in a temperate climate. Trees were irrigated in addition to precipitation. Three irrigation levels (0, 50 and 100%) were applied. Measurements included readings of apparent electrical conductivity of soil (ECa), stem water potential, canopy temperature obtained by infrared camera, and canopy volume estimated by LiDAR and RGB colour imaging. Laboratory analyses of 6 trees per treatment were done on fruit considering the pigment contents and quality parameters. Midday stem water potential (SWP), normalized crop water stress index (CWSI) calculated from thermal data, and fruit yield and quality at harvest were analysed. Spatial patterns of the variability of tree water status were estimated by CWSI imaging supported by SWP readings. CWSI ranged from 0.1 to 0.7 indicating high variability due to irrigation and precipitation. Canopy volume data were less variable. Soil ECa appeared homogeneous in the range of 0 to 4 mS m-1. Fruit harvested in a drought stress zone showed enhanced portion of pheophytin in the chlorophyll pool. Irrigation affected soluble solids content and, hence, the quality of fruit. Overall, results highlighted that spatial variation in orchards can be found even if marginal variability of soil properties can be assumed.
KW  - apple
KW  - CWSI
KW  - precision agriculture
KW  - management zone
Y1  - 2018
SN  - 978-94-62611-93-1
U6  - https://doi.org/10.17660/ActaHortic.2018.1197.19
SN  - 0567-7572
SN  - 2406-6168
VL  - 1197
SP  - 139
EP  - 146
PB  - International Society for Horticultural Science
CY  - The Hague
ER  - 
TY  - GEN
A1  - Rodriguez-Sillke, Yasmina
A1  - Steinhoff, U.
A1  - Bojarski, Christian
A1  - Lissner, Donata
A1  - Schumann, Michael
A1  - Branchi, F.
A1  - Siegmund, Britta
A1  - Glauben, Rainer
T1  - Deep immune profiling of human Peyer´s Patches in patients of inflammatory bowel diseases
T2  - European journal of immunology
Y1  - 2019
U6  - https://doi.org/10.1002/eji.201970300
SN  - 0014-2980
SN  - 1521-4141
VL  - 49
SP  - 203
EP  - 204
PB  - Wiley
CY  - Weinheim
ER  - 
TY  - GEN
A1  - Radchuk, Viktoriia
A1  - Kramer-Schadt, Stephanie
A1  - Grimm, Volker
T1  - Transferability of mechanistic ecological models is about emergence
T2  - Trends in ecology and evolution
Y1  - 2019
U6  - https://doi.org/10.1016/j.tree.2019.01.010
SN  - 0169-5347
SN  - 1872-8383
VL  - 34
IS  - 6
SP  - 487
EP  - 488
PB  - Elsevier
CY  - London
ER  - 
TY  - GEN
A1  - Pokorny, Ina
A1  - Sharma, Reeta
A1  - Goyal, Surendra Prakash
A1  - Mishra, Sudanshu
A1  - Tiedemann, Ralph
T1  - MHC class I and MHC class II DRB gene variability in wild and captive Bengal tigers (Panthera tigris tigris) (vol 10, pg 667, 2010)
T2  - Immunogenetics
Y1  - 2011
U6  - https://doi.org/10.1007/s00251-010-0496-2
SN  - 0093-7711
VL  - 63
IS  - 2
SP  - 121
EP  - 121
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Numberger, Daniela
A1  - Dreier, Carola
A1  - Vullioud, Colin
A1  - Gabriel, Guelsah
A1  - Greenwood, Alex D.
A1  - Grossart, Hans-Peter
T1  - Correction: Recovery of influenza A viruses from lake water and sediments by experimental inoculation (vol 14, e0216880, 2019)
T2  - PLoS one
Y1  - 2019
U6  - https://doi.org/10.1371/journal.pone.0218882
SN  - 1932-6203
VL  - 14
IS  - 6
PB  - PLoS
CY  - San Fransisco
ER  - 
TY  - GEN
A1  - Nikoloski, Zoran
A1  - van Dongen, Joost T.
T1  - Modeling alternatives for interpreting the change in oxygen-consumption rates during hypoxic conditions
T2  - New phytologist : international journal of plant science
KW  - hypoxia
KW  - modeling
KW  - regulation
KW  - respiration
KW  - roots
Y1  - 2011
U6  - https://doi.org/10.1111/j.1469-8137.2011.03674.x
SN  - 0028-646X
VL  - 190
IS  - 2
SP  - 273
EP  - 276
PB  - Wiley-Blackwell
CY  - Malden
ER  - 
TY  - GEN
A1  - Neye, Gundula
A1  - Wallschläger, Hans-Dieter
A1  - Tiedemann, Ralph
T1  - Song dialect boundaries in the Yellowhammer: Do they restrict gene flow?
T2  - Journal of ornithology
Y1  - 2006
SN  - 0021-8375
VL  - 147
IS  - Supplement 1
SP  - 219
EP  - 219
PB  - Blackwell
CY  - New York
ER  - 
TY  - GEN
A1  - Nathan, Ran
A1  - Horvitz, Nir
A1  - He, Yanping
A1  - Kuparinen, Anna
A1  - Schurr, Frank Martin
A1  - Katul, Gabriel G.
T1  - Spread of North American wind-dispersed trees in future environments
T2  - Ecology letters
N2  - P>Despite ample research, understanding plant spread and predicting their ability to track projected climate changes remain a formidable challenge to be confronted. We modelled the spread of North American wind-dispersed trees in current and future (c. 2060) conditions, accounting for variation in 10 key dispersal, demographic and environmental factors affecting population spread. Predicted spread rates vary substantially among 12 study species, primarily due to inter-specific variation in maturation age, fecundity and seed terminal velocity. Future spread is predicted to be faster if atmospheric CO2 enrichment would increase fecundity and advance maturation, irrespective of the projected changes in mean surface windspeed. Yet, for only a few species, predicted wind-driven spread will match future climate changes, conditioned on seed abscission occurring only in strong winds and environmental conditions favouring high survival of the farthest-dispersed seeds. Because such conditions are unlikely, North American wind-dispersed trees are expected to lag behind the projected climate range shift.
KW  - Climate change
KW  - demography
KW  - dispersal
KW  - fat-tailed dispersal kernels
KW  - forecasting
KW  - forests
KW  - invasion by extremes
KW  - long-distance dispersal
KW  - mechanistic models
KW  - plant migration
KW  - population spread
KW  - range expansion
KW  - survival
KW  - wind dispersal
Y1  - 2011
U6  - https://doi.org/10.1111/j.1461-0248.2010.01573.x
SN  - 1461-023X
VL  - 14
IS  - 3
SP  - 211
EP  - 219
PB  - Wiley-Blackwell
CY  - Malden
ER  - 
TY  - GEN
A1  - Müller-Schöll, A.
A1  - Klopp-Schulze, Lena
A1  - Huisinga, Wilhelm
A1  - Jörger, M.
A1  - Neven, P.
A1  - Koolen, S. L.
A1  - Mathijssen, R. H. J.
A1  - Schmidt, S.
A1  - Kloft, Charlotte
T1  - Patient-tailored tamoxifen dosing based on an increased quantitative understanding of its complex pharmacokinetics: A novel integrative modelling approach
T2  - Annals of Oncology
Y1  - 2019
SN  - 0923-7534
SN  - 1569-8041
VL  - 30
PB  - Oxford Univ. Press
CY  - Oxford
ER  - 
TY  - GEN
A1  - Moga, A.
A1  - Robinson, T.
A1  - Leimkühler, Silke
T1  - Towards reconstituting a biosynthetic pathway within compartmentalized GUVs
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2019
SN  - 0175-7571
SN  - 1432-1017
VL  - 48
SP  - S218
EP  - S218
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Messerschmidt, Katrin
A1  - Machens, Fabian
A1  - Hochrein, Lena
A1  - Naseri, Gita
T1  - Orthogonal, light-inducible protein expression platform in yeast Sacchararomyces cerevisiae
T2  - New biotechnology
Y1  - 2018
U6  - https://doi.org/10.1016/j.nbt.2018.05.153
SN  - 1871-6784
SN  - 1876-4347
VL  - 44
SP  - S19
EP  - S19
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Maier, Natalia
A1  - Holzlöhner, Pamela
A1  - Hoenow, Anja
A1  - Scheunemann, Astrid
A1  - Weschke, Daniel
A1  - Hanack, Katja
T1  - Characterization of monoclonal antibodies generated by in vitro immunization
T2  - The journal of immunology
N2  - Monoclonal antibodies are highly valuable tools in biomedicine but the generation by hybridoma technology is very time-consuming and elaborate. In order to circumvent the consisting drawbacks an in vitro immunization approach was established by which murine as well as human monoclonal antibodies against a viral coat protein could be developed. The in vitro immunization process was performed by isolation of murine hematopoietic stem cells or human monocytes and an in vitro differentiation into immature dendritic cells. After antigen loading the cells were co-cultivated with naive T and B lymphocytes for three days in order to obtain antigen-specific B lymphocytes in culture, followed by fusion with murine myeloma cells or human/murine heteromyeloma cells. Antigen-specific hybridomas were selected and the generated antibodies were purified and characterized in this study by ELISA, western blot, gene sequencing, affinity measurements. Further the characteristics were compared to a monoclonal antibody against the same target generated by conventional hybridoma technology. Isotype detection revealed a murine IgM and a human IgG4 antibody in comparison to an IgG1 for the conventionally generated antibody. The antibodies derived from in vitro immunization showed indeed a lower affinity for the antigen as compared to the conventionally generated one, which is probably based on the significantly shorter B cell maturation (3 days) during the immunization process. Nevertheless, they were suitable for building up a sandwich based detection system. Therefore, the in vitro immunization approach seems to be a good and particularly fast alternative to conventional hybridoma technology.
Y1  - 2016
SN  - 0022-1767
SN  - 1550-6606
VL  - 196
PB  - American Assoc. of Immunologists
CY  - Bethesda
ER  - 
TY  - GEN
A1  - Madden, Joah R.
A1  - Dingle, Caroline
A1  - Isden, Jess
A1  - Sparteld, Janka
A1  - Goldizen, Anne W.
A1  - Endler, John A.
T1  - Male spotted bowerbirds propagate fruit for use in their sexual display
T2  - Current biology
Y1  - 2012
U6  - https://doi.org/10.1016/j.cub.2012.02.057
SN  - 0960-9822
VL  - 22
IS  - 8
SP  - R264
EP  - R265
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Luckner, Madlen
A1  - Dunsing, Valentin
A1  - Drüke, Markus
A1  - Zuehlke, B.
A1  - Petazzi, Roberto Arturo
A1  - Chiantia, Salvatore
A1  - Herrmann, A.
T1  - Quantifying protein oligomerization directly in living cells
BT  - a systematic comparison of fluorescent proteins and application to Influenza A virus infection
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2019
SN  - 0175-7571
SN  - 1432-1017
VL  - 48
SP  - S183
EP  - S183
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Luckner, Madlen
A1  - Dunsing, Valentin
A1  - Chiantia, Salvatore
A1  - Herrmann, Andreas
T1  - Influenza virus vRNPs: quantitative investigations via fluorescence
cross-correlation spectroscopy
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S368
EP  - S368
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Luckner, Madlen
A1  - Dunsing, Valentin
A1  - Chiantia, Salvatore
A1  - Hermann, Andreas
T1  - Oligomerization and nuclear shuttling dynamics of viral proteins studied by quantitative molecular brightness analysis using fluorescence correlation spectroscopy
T2  - Biophysical journal
Y1  - 2018
U6  - https://doi.org/10.1016/j.bpj.2017.11.1951
SN  - 0006-3495
SN  - 1542-0086
VL  - 114
IS  - 3
SP  - 350A
EP  - 350A
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Lou, Ying
A1  - Ma, Hui
A1  - Lin, Wen-Hui
A1  - Chu, Zhao-Quing
A1  - Müller-Röber, Bernd
A1  - Xu, Zhi-Hong
A1  - Xue, Hong-Wei
T1  - The highly charged region of plant beta-type phosphatidylinositol 4-kinase is involved in membrane targeting and phospholipid binding
N2  - In Arabidopsis thaliana and Oryza sativa, two types of PI 4-kinase (PI4Ks) have been isolated and functionally characterized. The alpha-type PI4Ks (similar to 220 kDa) contain a PH domain, which is lacking in beta-type PI4Ks (similar to 120 kDa). beta-Type PI4Ks, exemplified by Arabidopsis AtPI4K beta and rice OsPI4K2, contain a highly charged repetitive segment designated PPC (Plant PI4K Charged) region, which is an unique domain only found in plant beta-type PI4Ks at present. The PPC region has a length of similar to 300 amino acids and harboring 11 (AtPI4K beta) and 14 (OsPI4K2) repeats, respectively, of a 20-aa motif. Studies employing a modified yeast-based "Sequence of Membrane- Targeting Detection'' system demonstrate that the PPC(OsPI4K2) region, as well as the former 8 and latter 6 repetitive motifs within the PPC region, are able to target fusion proteins to the plasma membrane. Further detection on the transiently expressed GFP fusion proteins in onion epidermal cells showed that the PPC(OsPI4K2) region alone, as well as the region containing repetitive motifs 1-8, was able to direct GFP to the plasma membrane, while the regions containing less repetitive motifs, i.e. 6, 4, 2 or single motif(s) led to predominantly intracellular localization. Agrobacterium-mediated transient expression of PPC-GFP fusion protein further confirms the membrane-targeting capacities of PPC region. In addition, the predominant plasma membrane localization of AtPI4Kb was mediated by the PPC region. Recombinant PPC peptide, expressed in E. coli, strongly binds phosphatidic acid, PI and PI4P, but not phosphatidylcholine, PI5P, or PI(4,5) P-2 in vitro, providing insights into potential mechanisms for regulating sub- cellular localization and lipid binding for the plant beta-type PI4Ks
Y1  - 2006
UR  - http://www.springerlink.com/content/100330
U6  - https://doi.org/10.1007/s11103-005-5548-x
SN  - 0167-4412
ER  - 
TY  - GEN
A1  - Lenhard, Michael
T1  - Plant Development: Keeping on the Straight and Narrow and Flat
T2  - Current biology
Y1  - 2017
U6  - https://doi.org/10.1016/j.cub.2017.10.030
SN  - 0960-9822
SN  - 1879-0445
VL  - 27
SP  - R1277
EP  - R1280
PB  - Cell Press
CY  - Cambridge
ER  - 
TY  - GEN
A1  - Lechon, Tamara
A1  - Sanz, Luis
A1  - Pollmann, Stephan
A1  - Sauer, Michael
A1  - Sandalio, Luisa
A1  - Lorenzo, Oscar
T1  - Nitric oxide modification of plant endocytosis and PIN1 localization
T2  - New biotechnology
Y1  - 2016
U6  - https://doi.org/10.1016/j.nbt.2015.10.028
SN  - 1871-6784
SN  - 1876-4347
VL  - 33
SP  - 424
EP  - 424
PB  - Elsevier
CY  - Amsterdam
ER  - 
TY  - GEN
A1  - Laux, Eva-Maria
A1  - Knigge, Xenia
A1  - Wenger, C.
A1  - Bier, Frank Fabian
A1  - Hölzel, Ralph
T1  - AC electrokinetic manipulation of nanoparticles and molecules
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S189
EP  - S189
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Laux, Eva-Maria
A1  - Gibbons, J.
A1  - Ermilova, Elena
A1  - Bier, Frank Fabian
A1  - Hölzel, Ralph
T1  - Broadband dielectric spectroscopy of bovine serum albumin in the GHz
range
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S347
EP  - S347
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Laux, Eva-Maria
A1  - Docoslis, A.
A1  - Wenger, C.
A1  - Bier, Frank Fabian
A1  - Hölzel, Ralph
T1  - Combination of dielectrophoresis and SERS for bacteria detection and characterization
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S331
EP  - S331
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Köchy, Martin
T1  - Photodegradation of grass litter in semi-arid grasslands : a global perspective
N2  - In a recent contribution in Nature (vol. 442, pp. 555-558) Austin & Vivanco showed that sunlight is the dominant factor for decomposition of grass litter in a semi-arid grassland in Argentine. The quantification of this effect was portrayed as a novel finding. I put this result in the context of three other publications from as early as 1980 that quantified photodegradation. My synopsis shows that photodegradation is an important process in semi-arid grasslands in South America, North America and eastern Europe.
KW  - Laubstreu
KW  - semi-arides Grasland
KW  - abiotische Zersetzung
KW  - UV-Licht
KW  - Schatten
KW  - leaf litter
KW  - semi-arid grassland
KW  - abiotic decomposition
KW  - UV radiation
KW  - shade
Y1  - 2006
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus-12006
ER  - 
TY  - GEN
A1  - Kramer, Elena M.
A1  - Lenhard, Michael
T1  - Shape and form in plant development
T2  - Seminars in cell & developmental biology
Y1  - 2017
U6  - https://doi.org/10.1016/j.semcdb.2017.11.004
SN  - 1084-9521
VL  - 79
SP  - 1
EP  - 2
PB  - Elsevier
CY  - London
ER  - 
TY  - GEN
A1  - Koziel, Slawomir
A1  - Hermanussen, Michael
A1  - Gomula, Alexandra
A1  - Swanson, James
A1  - Kaczmarek, Maria
A1  - El-Shabrawi, Mortada
A1  - Elhusseini, Mona
A1  - Satake, Takashi
A1  - Martinovic Klaric, Irena
A1  - Scheffler, Christiane
A1  - Morkuniene, Ruta
A1  - Godina, Elena
A1  - Sasa, Missoni
A1  - Tutkuviene, Janina
A1  - Siniarska, Anna
A1  - Nieczuja-Dwojacka, Joanna
A1  - Nunez, Javier
A1  - Groth, Detlef
A1  - Barbieri, Davide
T1  - Adolescence - a Transition to Adulthood Proceedings of the 24th Aschauer Soiree, held at Jurata, Poland, November 5th 2016
T2  - Pediatric Endocrinology Reviews
N2  - Eighteen scientists met at Jurata, Poland, to discuss various aspects of the transition from adolescence to adulthood. This transition is a delicate period facing complex interactions between the adolescents and the social group they belong to. Social identity, group identification and identity signalling, but also stress affecting basal salivary cortisol rhythms, hypertension, inappropriate nutrition causing latent and manifest obesity, moreover, in developing and under-developed countries, parasitosis causing anaemia thereby impairing growth and development, are issues to be dealt with during this period of the human development. In addition, some new aspects of the association between weight, height and head circumference in the newborns were discussed, as well as intrauterine head growth and head circumference as health risk indicators.
KW  - Strategic growth adjustment
KW  - BMI
KW  - Growth faltering
KW  - Secular trend
KW  - Obesity
KW  - Growth modelling
Y1  - 2017
SN  - 1565-4753
VL  - 14
IS  - 3
SP  - 326
EP  - 334
PB  - Medical Media
CY  - Netanya
ER  - 
TY  - GEN
A1  - Kocyan, Alexander
A1  - Wiland-Szymanska, Justyna
T1  - A new name and a new combination for Friedmannia nom. illeg. (Hypoxidaceae)
T2  - Phytotaxa : a rapid international journal for accelerating the publication of botanical taxonomy
N2  - Recently, Kocyan & Wiland-Szymańska (2016) have published a thorough research article on one of the outstanding members of the family Hypoxidaceae on the Seychelles, which resulted in the raise of a new genus (Friedmannia Kocyan & Wiland-Szymańska 2016: 60) to accommodate the former Curculigo seychellensis Bojer ex Baker (1877: 368). However, it has turned out that the name Friedmannia Chantanachat & Bold (1962: 45) already exists in literature for a green alga, which renders the new hypoxid genus illegitimate (Melbourne Code; McNeill et al. 2012). Therefore, we assign a new generic epithet to Curculigo seychellensis.
Y1  - 2017
U6  - https://doi.org/10.11646/phytotaxa.291.3.10
SN  - 1179-3155
SN  - 1179-3163
VL  - 291
IS  - 3
SP  - 239
EP  - 239
PB  - Magnolia Press
CY  - Auckland
ER  - 
TY  - GEN
A1  - Knigge, Xenia
A1  - Wenger, C.
A1  - Bier, Frank Fabian
A1  - Hölzel, Ralph
T1  - AC electrokinetic immobilisation of nanoobjects as individual singles in regular arrays
T2  - European biophysics journal : with biophysics letters ; an international journal of biophysics
Y1  - 2017
SN  - 0175-7571
SN  - 1432-1017
VL  - 46
SP  - S187
EP  - S187
PB  - Springer
CY  - New York
ER  - 
TY  - GEN
A1  - Kleine-Vehn, Jürgen
A1  - Sauer, Michael
ED  - Kleine-Vehn, Jürgen
ED  - Sauer, Michael
T1  - Preface
T2  - Plant Hormones: Methods and Protocols
Y1  - 2017
SN  - 978-1-4939-6469-7
SN  - 978-1-4939-6467-3
U6  - https://doi.org/10.1007/978-1-4939-6469-7
SN  - 1064-3745
SN  - 1940-6029
VL  - 1497
SP  - V
EP  - V
PB  - Springer
CY  - New York
ET  - 3
ER  - 
TY  - GEN
A1  - Kehr, Julia
T1  - Untersuchungen der Proteine in den Langstreckentransportsystemen höherer Pflanzen
Y1  - 2005
CY  - Potsdam
ER  - 
TY  - GEN
A1  - Kalinkat, Gregor
A1  - Cabral, Juliano Sarmento
A1  - Darwall, William
A1  - Ficetola, G. Francesco
A1  - Fisher, Judith L.
A1  - Giling, Darren P.
A1  - Gosselin, Marie-Pierre
A1  - Grossart, Hans-Peter
A1  - Jaehnig, Sonja C.
A1  - Jeschke, Jonathan M.
A1  - Knopf, Klaus
A1  - Larsen, Stefano
A1  - Onandia, Gabriela
A1  - Paetzig, Marlene
A1  - Saul, Wolf-Christian
A1  - Singer, Gabriel
A1  - Sperfeld, Erik
A1  - Jaric, Ivan
T1  - Flagship umbrella species needed for the conservation of overlooked aquatic biodiversity
T2  - Conservation biology : the journal of the Society for Conservation Biology
Y1  - 2017
U6  - https://doi.org/10.1111/cobi.12813
SN  - 0888-8892
SN  - 1523-1739
VL  - 31
SP  - 481
EP  - 485
PB  - Wiley
CY  - Hoboken
ER  -