TY - JOUR A1 - Belli, Francesco A1 - Felisatti, Arianna A1 - Fischer, Martin H. T1 - "BreaThink" BT - breathing affects production and perception of quantities JF - Experimental brain research N2 - Cognition is shaped by signals from outside and within the body. Following recent evidence of interoceptive signals modulating higher-level cognition, we examined whether breathing changes the production and perception of quantities. In Experiment 1, 22 adults verbally produced on average larger random numbers after inhaling than after exhaling. In Experiment 2, 24 further adults estimated the numerosity of dot patterns that were briefly shown after either inhaling or exhaling. Again, we obtained on average larger responses following inhalation than exhalation. These converging results extend models of situated cognition according to which higher-level cognition is sensitive to transient interoceptive states. KW - breathing KW - embodied cognition KW - interoception KW - numerical cognition KW - situated cognition Y1 - 2021 U6 - https://doi.org/10.1007/s00221-021-06147-z SN - 0014-4819 SN - 1432-1106 VL - 239 IS - 8 SP - 2489 EP - 2499 PB - Springer CY - New York ER - TY - THES A1 - Arnold, Maren T1 - "Der Fall Collini" von Ferdinand von Schirach als Narration für politisch-rechtliches Lernen im Politikunterricht T1 - "The Collini Case" by Ferdinand von Schirach as a narration for political and legal learning in Civic Education N2 - In den vergangenen Jahren hat sich die Politikdidaktik zunehmend mit dem Einsatz von Narrationen im Politikunterricht beschäftigt, denn neben Sachtexten bietet auch die Belletristik die Möglichkeit, sich mit politischen Themen auseinanderzusetzen. Insbesondere die Literatur von Ferdinand von Schirach hat in den letzten Jahren zunehmend Anklang in der Gesellschaft gefunden. Von Schirachs Texte greifen gesellschaftskritische Themen auf, beleuchten diese aus verschiedenen Perspektiven und fordern zur Meinungsbildung heraus. Aus diesem Grund weisen von Schirachs Narrationen ein hohes Potential für die Politische Bildung auf. Politische Bildung schließt auch die Rechterziehung ein. Der Fall Collini von Ferdinand von Schirach setzt sich sowohl mit rechtlichen, als auch mit politischen Themen im Sinne der Rechtserziehung auseinander. In der vorliegenden Masterarbeit wird der Frage nachgegangen, inwieweit der Roman Der Fall Collini von Ferdinand von Schirach als Narration eine Chance für politisch-rechtliches Lernen im Politikunterricht darstellt. Um die Forschungsfrage zu beantworten, werden die Lernchancen und -grenzen des Romans hinsichtlich seiner Thematik und seines Genres, sowie durch den Roman geförderten Kompetenzen herausgearbeitet und die durch ihn möglichen fächerübergreifenden Bezüge verdeutlicht. Durch die Auseinandersetzung mit von Schirachs Werk beschäftigen sich die Schülerinnen und Schüler mit politisch-rechtlichen Themen, wie dem Spannungsverhältnis von Recht und Gerechtigkeit, dem Ablauf von Strafgerichtsverfahren, dem theoretischen Anspruch des Rechtsstaates und dessen realen Schwächen. Zudem fördert die Auseinandersetzung mit dem Roman Der Fall Collini die vier fachbezogenen Kompetenzen der Politischen Bildung, sowie Multiperspektivität und exemplarisches Lernen. Des Weiteren verknüpft der Roman historische, politisch-rechtliche und moralisch-ethische Aspekte miteinander, wodurch fächerübergreifende Bezüge mit den Fächern Geschichte, Deutsch und L-E-R hergestellt werden können. Darüber hinaus spricht der Justizroman als Narration seine Leserinnen und Leser auch emotional an und fördert somit eine ganzheitliche und nachhaltige Wissensvermittlung im Sinne der Rechtserziehung. Es hat sich gezeigt, dass Der Fall Collini von Ferdinand von Schirach sich für die unterrichtliche Beschäftigung innerhalb der Politischen Bildung besonders eignet. N2 - In recent years, political didactics has increasingly engaged in the use of narrations for Civic Education in school. In addition to non-fictional texts, fiction also offers the opportunity to deal with political issues. As the fictional literature of Ferdinand von Schirach has successfully drawn society’s attention towards political and legal issues over the past few years, it might be a valuable contribution to Civic Education. Von Schirach’s texts take up critical issues, illuminate them from different perspectives and challenge people to form their opinions. For those reasons, von Schirach’s narrations, especially The Collini Case, have a high didactical potential to promote their political and legal learning. In this Master’s thesis, I will examine the question to what extent Ferdinand von Schirach’s novel The Collini Case encourages a critical awareness for such issues, as well as political and legal learning. In order to answer this research question, the learning opportunities and limits of the novel with regards to its subject matter and genre, as well as the competencies promoted by the novel, are identified and the interdisciplinary refences are elucidated. Von Schirach’s literature confronts students with different issues such as the tension between law and justice, the course of criminal court proceedings, the theoretical claims of the constitutional state and its weaknesses considering reality. In addition, reading the novel The Collini Case facilitates the four subject-related competencies of Civic Education, as well as multi-perspectivity and exemplary learning. Furthermore, the novel links historical, political-legal and moral-ethical aspects with one another, which enables interdisciplinary references to be made with the subjects of History, German and Ethics. Moreover, the novel also speaks to its readers on an emotional level and thus enables a holistic and sustainable transfer of knowledge. All in all, the analysis has shown that Ferdinand von Schirach’s The Collini Case is particularly suitable for teaching politics. KW - Narration KW - (Justiz-) Roman KW - Recht KW - Gerechtigkeit KW - Rechtsstaat KW - Strafgerichtsverfahren KW - Kompetenzen KW - Politische Bildung KW - Der Fall Collini KW - Ferdinand von Schirach KW - narration KW - novel KW - law KW - justice KW - constitutional state KW - criminal proceeding KW - competencies KW - Civic Education KW - The Collini Case KW - Ferdinand von Schirach Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-512851 ER - TY - JOUR A1 - Harmanli, İpek A1 - Tarakina, Nadezda A1 - Antonietti, Markus A1 - Oschatz, Martin T1 - "Giant" nitrogen uptake in ionic liquids confined in carbon pores JF - Journal of the American Chemical Society N2 - Ionic liquids are well known for their high gas absorption capacity. It is shown that this is not a solvent constant, but can be enhanced by another factor of 10 by pore confinement, here of the ionic liquid (IL) 1-ethyl-3-methylimidazolium acetate (EmimOAc) in the pores of carbon materials. A matrix of four different carbon compounds with micro- and mesopores as well as with and without nitrogen doping is utilized to investigate the influence of the carbons structure on the nitrogen uptake in the pore-confined EmimOAc. In general, the absorption is most improved for IL in micropores and in nitrogen-doped carbon. This effect is so large that it is already seen in TGA and DSC experiments. Due to the low vapor pressure of the IL, standard volumetric sorption experiments can be used to quantify details of this effect. It is reasoned that it is the change of the molecular arrangement of the ions in the restricted space of the pores that creates additional free volume to host molecular nitrogen. Y1 - 2021 U6 - https://doi.org/10.1021/jacs.1c00783 SN - 0002-7863 SN - 1520-5126 VL - 143 IS - 25 SP - 9377 EP - 9384 PB - American Chemical Society CY - Washington ER - TY - JOUR A1 - Sinha, Shreya A1 - Saalfrank, Peter T1 - "Inverted" CO molecules on NaCl(100) BT - a quantum mechanical study JF - Physical chemistry, chemical physics : a journal of European Chemical Societies N2 - Somewhat surprisingly, inverted ("O-down") CO adsorbates on NaCl(100) were recently observed experimentally after infrared vibrational excitation (Lau et al., Science, 2020, 367, 175-178). Here we characterize these species using periodic density functional theory and a quantum mechanical description of vibrations. We determine stationary points and minimum energy paths for CO inversion, for low (1/8 and 1/4 monolayers (ML)) and high (1 ML) coverages. Transition state theory is applied to estimate thermal rates for "C-down" to "O-down" isomerization and the reverse process. For the 1/4 ML p(1 x 1) structure, two-dimensional and three-dimensional potential energy surfaces and corresponding anharmonic vibrational eigenstates obtained from the time-independent nuclear Schrodinger equation are presented. We find (i) rather coverage-independent CO inversion energies (of about 0.08 eV or 8 kJ mol(-1) per CO) and corresponding classical activation energies for "C-down" to "O-down" isomerization (of about 0.15 eV or 14 kJ mol(-1) per CO); (ii) thermal isomerization rates at 22 K which are vanishingly small for the "C-down" to "O-down" isomerization but non-negligible for the back reaction; (iii) several "accidentally degenerate" pairs of eigenstates well below the barrier, each pair describing "C-down" to "O-down" localized states. Y1 - 2020 U6 - https://doi.org/10.1039/d0cp05198e SN - 1463-9076 SN - 1463-9084 VL - 23 IS - 13 SP - 7860 EP - 7874 PB - Royal Society of Chemistry CY - Cambridge ER - TY - JOUR A1 - Juang, Linda P. A1 - Schwarzenthal, Miriam A1 - Moffitt, Ursula Elinor A1 - Vietze, Jana T1 - "No, where are you really from?" BT - Testing the foreigner objectification scale with German adolescents BT - Testen der Foreigner Objectification Scale mit deutschen Jugendlichen JF - Zeitschrift für Entwicklungspsychologie und pädagogische Psychologie : Organ der Fachgruppen Entwicklungspsychologie und Pädagogische Psychologie der Deutschen Gesellschaft für Psychologie (DGPs) N2 - Being perceived as a foreigner regardless of one's generational status, citizenship, or self-identification is called foreigner objectification. This is a form of identity denial and is linked to psychological distress. To test how foreigner objectification could be measured in Europe, we assessed whether the Foreigner Objectification Scale demonstrated reliability and validity with German adolescents. The sample included 806 9th graders from 17 high schools. The results showed that the scale demonstrates good reliability, scalar measurement invariance across gender and citizenship status, and partial scalar measurement invariance across family heritage, generational status, and cultural self-identification. Adolescents who scored higher on the scale also reported greater school behavioral disengagement, lower life satisfaction, and stronger ethnic identity. Our findings suggest that the scale is psychometrically sound and is linked in theoretically consistent ways to adjustment and ethnic identity. We conclude that this scale offers another way to capture subtle discrimination experiences that add to a more comprehensive understanding of discrimination and the related implications in Europe. N2 - Als Ausländer_in wahrgenommen zu werden, unabhängig vom Generationsstatus, der Staatsbürgerschaft oder der Selbstidentifikation, wird „foreigner objectification“ (Ausländer_innenobjektifizierung) genannt. Ausländer_innenobjektifizierung ist eine Form der Identitätsverleugnung und wird mit größerem psychologischem Stress in Verbindung gebracht. Um zu testen, wie Ausländer_innenobjektifizierung in Europa gemessen werden kann, untersuchten wir, ob die Foreigner Objectification Scale bei deutschen Jugendlichen Reliabilität und Validität aufweist. Die Stichprobe umfasste 806 Neuntklässler_innen aus 17 Sekundarschulen. Die Ergebnisse zeigten, dass die Skala eine gute Reliabilität, skalare Messinvarianz über das Geschlecht und die Staatsbürgerschaft sowie eine partielle skalare Messinvarianz über die familiäre Herkunft, den Generationsstatus und die kulturelle Selbstidentifikation aufweist. Jugendliche, die höhere Werte auf der Skala erreichten, berichteten auch über ein größeres schulisches Disengagement, eine geringere Lebenszufriedenheit und eine stärkere ethnische Identität. Unsere Ergebnisse deuten darauf hin, dass die Skala psychometrisch solide ist und auf theoretisch konsistente Weise mit Adaptation und ethnischer Identität verbunden ist. Wir kommen zu dem Schluss, dass diese Skala eine weitere Möglichkeit bietet, subtile Diskriminierungserfahrungen zu erfassen, die zu einem umfassenderen Verständnis von Diskriminierung und deren Auswirkungen in Europa beitragen. T2 - „Nein, woher kommst du denn wirklich?” KW - discrimination KW - foreigner objectification KW - migration KW - microaggression KW - Diskriminierung KW - Ausländer_innenobjektifizierung KW - Migration KW - Mikroaggression Y1 - 2021 U6 - https://doi.org/10.1026/0049-8637/a000242 SN - 0049-8637 SN - 2190-6262 VL - 53 IS - 3-4 SP - 82 EP - 93 PB - Hogrefe CY - Göttingen ER - TY - JOUR A1 - Zhang, Xiaorong A1 - Caserta, Giorgio A1 - Yarman, Aysu A1 - Supala, Eszter A1 - Tadjoung Waffo, Armel Franklin A1 - Wollenberger, Ulla A1 - Gyurcsanyi, Robert E. A1 - Zebger, Ingo A1 - Scheller, Frieder W. T1 - "Out of Pocket" protein binding BT - a dilemma of epitope imprinted polymers revealed for human hemoglobin JF - Chemosensors N2 - The epitope imprinting approach applies exposed peptides as templates to synthesize Molecularly Imprinted Polymers (MIPs) for the recognition of the parent protein. While generally the template protein binding to such MIPs is considered to occur via the epitope-shaped cavities, unspecific interactions of the analyte with non-imprinted polymer as well as the detection method used may add to the complexity and interpretation of the target rebinding. To get new insights on the effects governing the rebinding of analytes, we electrosynthesized two epitope-imprinted polymers using the N-terminal pentapeptide VHLTP-amide of human hemoglobin (HbA) as the template. MIPs were prepared either by single-step electrosynthesis of scopoletin/pentapeptide mixtures or electropolymerization was performed after chemisorption of the cysteine extended VHLTP peptide. Rebinding of the target peptide and the parent HbA protein to the MIP nanofilms was quantified by square wave voltammetry using a redox probe gating, surface enhanced infrared absorption spectroscopy, and atomic force microscopy. While binding of the pentapeptide shows large influence of the amino acid sequence, all three methods revealed strong non-specific binding of HbA to both polyscopoletin-based MIPs with even higher affinities than the target peptides. KW - Molecularly Imprinted Polymers KW - epitope imprinting KW - non-specific KW - binding KW - redox gating KW - SEIRA spectroelectrochemistry Y1 - 2021 U6 - https://doi.org/10.3390/chemosensors9060128 SN - 2227-9040 VL - 9 IS - 6 PB - MDPI CY - Basel ER - TY - THES A1 - Schindler, Eva Marie T1 - "What we have done is just to put the people in form of a structure" T1 - "Wir haben die Leute einfach strukturiert" BT - The myth of participation and organisation of civil society BT - Der Mythos Partizipation und die Organisierung von Zivilgesellschaft N2 - Participation has become an orthodoxy in the field of development, an essential element of projects and programmes. This book analyses participation in development interventions as an institutionalised expectation – a rationalized myth – and examines how organisations on different levels of government process it. At least two different objectives of participation are appropriate and legitimate for international organisations in the field: the empowerment of local beneficiaries and the achievement of programme goals. Both integrate participatory forums into the organisational logic of development interventions. Local administrations react to the institutionalised expectation with means-ends decoupling, where participatory forums are implemented superficially but de facto remain marginalised in local administrative processes and activities. The book furthermore provides a thick description of the organisationality of participation in development interventions. Participatory forums are shown to be a form of partial organisation. They establish an order in the relationship between administrations and citizens through the introduction of rules and the creation of a defined membership. At the same time, this order is found to be fragile and subject to criticism and negotiation. N2 - Partizipation ist im Feld der Entwicklungszusammenarbeit eine Orthodoxie, ein unentbehrlicher Bestandteil von Projekten und Programmen. Die Arbeit versteht Partizipation in diesem Rahmen als Rationalitätsmythos und analysiert, wie diese institutionalisierte Erwartung von Verwaltungen auf verschiedenen Ebenen bearbeitet wird. Aus der Perspektive internationaler Organisationen existieren im Feld der Entwicklungszusammenarbeit mit dem Empowerment der lokalen Bevölkerung und der Erreichung von Programmzielen zwei angemessene und legitime Zielsetzungen von Partizipation. Beide ermöglichen eine Integration von Partizipation in die Logik von Projekten und Programmen. Lokale Verwaltungen begegnen der institutionalisierten Erwartung mit einer Zweck-Mittel-Entkopplung, bei der Partizipationsforen oberflächlich implementiert, aber in lokalen Verwaltungsprozessen und -aktivitäten de facto marginalisiert werden. Der Organisationsförmigkeit von Partizipation nähert sich die Arbeit durch dichte Beschreibung ihrer Organisationselemente. Die Partizipationsforen werden als eine Form partieller Organisation verstanden, die dem Verhältnis zwischen lokaler Verwaltung und Bürgern eine Ordnung aus Regeln und Mitgliedschaft auferlegt. Gleichzeitig zeigen die Forschungsergebnisse die Fragilität dieser Ordnung auf und legen dar, wie sie hinterfragt und verhandelt wird. KW - participation KW - development interventions KW - organisationality KW - organizational sociology KW - ethnography KW - interpretive research KW - Partizipation KW - Entwicklungszusammenarbeit KW - Organisationsförmigkeit KW - Organisationssoziologie KW - Ethnographie KW - interpretative Forschung Y1 - 2021 ER - TY - JOUR A1 - Hänel, Hilkje Charlotte T1 - #MeToo and testimonial injustice BT - an investigation of moral and conceptual knowledge JF - Philosophy and Social Criticism N2 - Two decades ago, Tarana Burke started using the phrase ‘me too’ to release victims of sexual abuse and rape from their shame and to empower girls from minority communities. In 2017, actress Alyssa Milano made the hashtag #MeToo go viral. This article’s concern is with the role of testimonial practices in the context of sexual violence. While many feminists have claimed that the word of those who claim to being sexually violated by others (should) have political and/or epistemic priority, others have failed to recognize the harm and injury of instances of sexual violence that are not yet acknowledged as such and failed to listen to victims from marginalized social groups. In fact, some feminists have attacked #MeToo for mingling accounts of ‘proper’ sexual violence and accounts that are not ‘proper’ experiences of sexual violence. My aim in this article is to show why this critique is problematic and find a philosophically fruitful way to understand the #MeToo-movement as a movement that strives for moral and conceptual progress. Y1 - 2021 U6 - https://doi.org/10.1177/01914537211017578 SN - 0191-4537 SN - 1461-734X VL - 48 IS - 6 SP - 833 EP - 859 PB - Sage Publ. CY - London ER - TY - GEN A1 - Hinz, Carsten A1 - Löffler, Robert A1 - Deeken, Johannes A1 - Hansen, Barbara A1 - Huhn, Nicola A1 - Klitsch, Constantin A1 - Kost, André A1 - Penning, Isabelle A1 - Richter, Christin A1 - Schäfer, David A1 - Schulz, Oliver A1 - Simon, Veronika A1 - Tuncel, Teresa T1 - #Politik Wirtschaft – Nordrhein-Westfalen. Band 7/8 BT - Wirtschaft für die Realschule, Gesamtschule und Sekundarschule N2 - Seit dem Schuljahr 2020/21 gilt in Nordrhein-Westfalen ein neuer Kernlehrplan für die Realschule, Gesamtschule und Sekundarschule. Dafür haben wir gemeinsam mit Fachkräften aus dem Bundesland die #-Schulbuchreihen entwickelt. Mit #Politik Wirtschaft – Nordrhein-Westfalen bieten wir Ihnen innovative und aktuelle Produkte für einen modernen Politik- und Wirtschaftsunterricht. Neben dem neuen Lehrplan sind die Vorgaben des Medienkompetenzrahmens und die besonderen Herausforderungen heterogener Lerngruppen berücksichtigt. Wir bieten Ihnen einen problemorientierten und schülernahen Unterricht. Die Rubrik ”Gemeinsam aktiv“ ermöglicht ein selbstgesteuertes Lernen. Die Schülerinnen und Schüler erarbeiten sich projektartig größere Einheiten eines Kapitels. Sie können Ihren Unterricht einfach und schnell besonders vielfältig und spannend gestalten. Durch Fallbeispiele werden die Schülerinnen und Schüler direkt angesprochen. Eine kreative Vielfalt aus Bild-, Grafik- und Textmaterial, aktivierende Aufgaben, Methoden-und Grundwissenseiten und ein Kompetenzcheck zum Abschluss der Großkapitel vervollständigen das Angebot. Zu jeder Unterrichtseinheit wird passgenau zum Schulbuch unterschiedliches Differenzierungsmaterial (Texte in einfacher Sprache, Vorstrukturierung von Aufgaben u.v.m.) erstellt. Dieses steht Ihnen in unserem digitalen Lehrermaterial click & teach zur Verfügung und kann von Ihnen nach individuellen Bedürfnissen für einzelne digitale Schulbücher click & study freigeschaltet werden. Y1 - 2021 SN - 978-3-661-70077-9 PB - Buchner CY - Bamberg ER - TY - JOUR A1 - Salzer, Leonhard A1 - Nöbauer, Anna ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - (Auf) Humboldts Spuren BT - eine bauforscherische Untersuchung der „Casa Humboldt“ am Antisana in Ecuador T2 - HiN : Alexander von Humboldt im Netz N2 - Vor seiner Besteigung des Antisana in Ecuador verbrachte Alexander von Humboldt mit seinem Expeditionsteam die Nacht vom 15. auf den 16. März 1802 in einer Hacienda am Fuße des Vulkangipfels, deren letztes bauliches Zeugnis eine steinerne Hütte darstellt. Bauforscherische Untersuchungen eines internationalen Forscherteams konnten die mehrschichtige Bau- und Reparaturgeschichte dieses Baudenkmals ermitteln und über eine Auswertung von Reiseberichten mehrerer Andenforscher die Nutzungsgeschichte des einzelnen Gebäudes und des gesamten Anwesens klären. Schließlich ergaben sich daraus neue Erkenntnisse zu Humboldts Aufenthalt am Antisana. N2 - Before climbing the Antisana in Ecuador, Alexander von Humboldt and his expedition team encamped at a hacienda at the foot of the volcano’s summit in the night from 15 to 16 March 1802. A stone hut is the only structural testimony of this estate that remains today. Through building archaeological investigations, an international team of researchers was able to determine the construction and restoration history of this monument. An evaluation of the descriptions of the hacienda in 19th- and early 20th-century travel accounts clarified the historical use of the estate and, in particular, the existing hut, thus shedding new light on Humboldt’s stay in 1802. N2 - Previamente a su ascensión del volcán Antisana en Ecuador, Alexander von Humboldt se hospedó la noche del 15 al 16 de marzo de 1802 en una hacienda al pie del volcán, juntamente con el equipo que le acompañaba en su expedición. Si bien el último atestado que se tenía de esta comprendía una cabaña de piedra, nuevas investigaciones sobre arqueología vertical por parte de un equipo de investigación internacional muestran una nueva historia de construcción y reparación de este monumento histórico. Con ello, se pretende, por una parte, valorar en detalle las crónicas de viaje de múltiples investigadores de los Andes, así como, por otra, esclarecer la historia constructiva y de utilización de la singular edifi cación así como su papel dentro de la propiedad en que se encuentra. A través de esta investigación aparecen nuevos conocimientos sobre la estancia de Humboldt en el Antisana. KW - Bauforschung KW - Ecuador KW - Antisana KW - Hacienda de Antisana Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-533271 SN - 2568-3543 SN - 1617-5239 VL - XXII IS - 43 SP - 65 EP - 82 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Brechenmacher, Thomas T1 - 1961: Die Kirchen zum Eichmann-Prozeß JF - Mitteilungen zur kirchlichen Zeitgeschichte Y1 - 2021 SN - 2699-3074 SN - 1866-8771 VL - 15 SP - 75 EP - 96 PB - Evangelische Arbeitsgemeinschaft für Kirchliche Zeitgeschichte CY - München ER - TY - BOOK T1 - 30 Jahre Universität Potsdam N2 - Das Referat für Presse- und Öffentlichkeitsarbeit hat anlässlich des 30-jährigen Universitätsjubiläums einen Bildband zusammengestellt. Auf 168 Seiten finden sich rund 400 Fotos aus der Geschichte der Potsdamer Alma Mater – von der Pressekonferenz, auf der Brandenburgs Wissenschaftsminister Dr. Hinrich Enderlein die Gründung der Universität bekannt gibt, bis zu den traurig-schönen menschenleeren Campusimpressionen Anfang 2021. Die Auswahl aus Zehntausenden Bildern, die im Laufe der Jahre entstanden sind, dokumentiert die rasante Entwicklung der drei Uni-Standorte Golm, Am Neuen Palais und Griebnitzsee, begleitet Studierende und Forschende verschiedener Generationen und zeigt Eindrücke von wichtigen großen und kleinen Veranstaltungen und Ereignissen sowie – vor allem – vom Alltag einer Universität. Y1 - 2021 PB - Universität Potsdam, Referat für Presse- und Öffentlichkeitsarbeit CY - Potsdam ER - TY - JOUR A1 - Koyan, Philipp A1 - Tronicke, Jens A1 - Allroggen, Niklas T1 - 3D ground-penetrating radar attributes to generate classified facies models BT - a case study from a dune island JF - Geophysics N2 - Ground-penetrating radar (GPR) is a standard geophysical technique used to image near-surface structures in sedimentary environments. In such environments, GPR data acquisition and processing are increasingly following 3D strategies. However, the processed GPR data volumes are typically still interpreted using selected 2D slices and manual concepts such as GPR facies analyses. In seismic volume interpretation, the application of (semi-)automated and reproducible approaches such as 3D attribute analyses as well as the production of attribute-based facies models are common practices today. In contrast, the field of 3D GPR attribute analyses and corresponding facies models is largely untapped. We have developed and applied a workflow to produce 3D attribute-based GPR facies models comprising the dominant sedimentary reflection patterns in a GPR volume, which images complex sandy structures on the dune island of Spiekeroog (Northern Germany). After presenting our field site and details regarding our data acquisition and processing, we calculate and filter 3D texture attributes to generate a database comprising the dominant texture features of our GPR data. Then, we perform a dimensionality reduction of this database to obtain meta texture attributes, which we analyze and integrate using composite imaging and (also considering additional geometric information) fuzzy c-means cluster analysis resulting in a classified GPR facies model. Considering our facies model and a corresponding GPR facies chart, we interpret our GPR data set in terms of near-surface sedimentary units, the corresponding depositional environments, and the recent formation history at our field site. Thus, we demonstrate the potential of our workflow, which represents a novel and clear strategy to perform a more objective and consistent interpretation of 3D GPR data collected across different sedimentary environments. KW - ground-penetrating radar KW - attributes KW - interpretation KW - sedimentology Y1 - 2021 U6 - https://doi.org/10.1190/GEO2021-0204.1 SN - 0016-8033 SN - 1942-2156 VL - 86 IS - 6 SP - B335 EP - B347 PB - Society of Exploration Geophysicists CY - Tulsa ER - TY - THES A1 - Rehse, Jessica T1 - 3D-Druck und 3D-Modellierung im Wirtschaft-Arbeit-Technik-Unterricht T1 - 3D printing and 3D modeling in economy-work-technology lessons N2 - Die Technologie des 3D-Drucks hat sich in den letzten Jahrzehnten rasant entwickelt. Im Industriebereich entstehen immer modernere und spezialisiertere Druckverfahren, im Hobby- und Privatanwenderbereich hingegen werden stetig kostengünstigere und einfacher zu bedienende Geräte zugänglich. Einzig im Bildungsbereich scheint das Themenfeld hingegen erst langsam eine Rolle zu spielen, obwohl sich zahlreiche Bezugspunkte für einen Einsatz in verschiedensten Fächern finden lassen. Insbesondere im Fach Wirtschaft-Arbeit-Technik sind die Schnittstellen zum Rahmenlehrplan Berlin/Brandenburg augenscheinlich, doch es liegen erst vereinzelt konkrete und systematische didaktische Konzepte und Vorschläge zur unterrichtspraktischen Einbettung vor. Die Verfasserin versucht daher in dieser Arbeit die Relevanz des Themas für die technische Bildung deutlich zu machen, eine kurze technische Einführung in das für einen schulischen Einsatz besonders geeignete FDM-Druckverfahren zu geben und daran anknüpfend konkrete Umsetzungsvorschläge aufzuzeigen: einerseits in Form eines allgemeinen Phasenmodells zur Planung von Technikunterricht sowie andererseits in Form eines exemplarischen Unterrichtskonzepts. Am Beispiel eines Schachsets wird verdeutlicht, wie Schülerinnen und Schüler zum Anfertigen der Konstruktionsunterlagen digitale CAD-Programme nutzen und anschließend mit Hilfe eines 3D-Druckers additiv fertigen können. N2 - While 3D printing technology is now becoming increasingly widespread in both industry and the private sector, it has so far rarely been used in educational processes. Things are going way slower here, even though there are many school subjects which would perfectly fit for it. The intersections to the Berlin/Brandenburg framework curriculum are particularly obvious in the subject of economy-work-technology. However, there are only a few concrete and systematic didactic concepts and suggestions for the practical embedding in lessons. The author therefore attempts in this paper to make clear the relevance of the topic for technical education and to give a brief technical introduction to the FDM printing process, which is particularly suitable for use in schools. Following on from this, she attempts to show concrete suggestions for implementation: on the one hand, in the form of a general phase model for planning technology lessons and, on the other, in the form of an exemplary teaching concept. The example of a chess set is used to illustrate how students can use digital CAD programs to create the designs and then manufacture them additively with the aid of a 3D printer. KW - 3D-Druck KW - FDM-Druck KW - 3D-Modellierung KW - 3D-Konstruktion KW - CAD KW - Digitale Bildung KW - Technische Bildung KW - WAT KW - Wirtschaft-Arbeit-Technik KW - Technikdidaktik KW - Konstruktionsaufgabe KW - Unterrichtskonzept KW - 3D printing KW - FDM printing KW - 3D modeling KW - 3D design KW - CAD KW - digital education KW - technical education KW - WAT KW - economy-work-technology KW - technology didactics KW - design task KW - teaching concept Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-524485 ER - TY - JOUR A1 - Gerhard, Reimund T1 - 50 years of International Symposia on Electrets from 1967 to 2017 BT - a global history JF - IEEE electrical insulation magazine / Institute of Electrical and Electronics Engineers N2 - The prehistory of electrets is not known yet, but it is quite likely that the electrostatic charging behavior of amber (Greek: τò ηλεκτρoν, i.e., “electron”) already was familiar to people in ancient cultures (China, Egypt, Greece, etc.), before the Greek philosopher and scientist Thales of Miletus (6th century BCE)-or rather his disciples and followers-reported it in writing (cf. Figure 1). More than two millennia later, William Gilbert (1544–1603), the physician of Queen Elizabeth I, coined the term “electric” in his book De Magnete, Magneticisque Corporibus, et de Magno Magnete Tellure (1600) for dielectric materials that attract like amber and that included sulfur and glass [1]. The second half of the 18th century saw the invention of the electrophorus or electrophore [2], a capacitive electret device, in 1762 by Johan Carl Wilcke (1732–1796). Y1 - 2021 U6 - https://doi.org/10.1109/MEI.2021.9352710 SN - 0883-7554 SN - 1558-4402 VL - 37 IS - 2 SP - 50 EP - 55 PB - IEEE CY - New York, NY ER - TY - JOUR A1 - Zimmermann, Andreas A1 - Herrmann, Franziska T1 - 70 Jahre Genfer Flüchtlingskonvention BT - Versuch einer Bilanz JF - Informationsbrief Ausländerrecht Y1 - 2021 UR - https://research.wolterskluwer-online.de/document/2c925f57-8d47-351f-87f5-26bc36668bb7 SN - 0174-2108 SN - 2366-195X IS - 6 SP - 221 EP - 227 PB - Luchterhand CY - Köln ; Neuwied ER - TY - JOUR A1 - Sperlich, Eric A1 - Köckerling, Martin T1 - [Nb6Cl12(CH3OH)4(OCH3)2] ⋅ DABCO ⋅ 1.66 CH2Cl2 BT - cluster units wrapped in a network of hydrogen bonds JF - Zeitschrift für anorganische und allgemeine Chemie : ZAAC = Journal of inorganic and general chemistry N2 - An easy-to-do synthesis for the hexanuclear niobium cluster compound [Nb6Cl12(CH3OH)(4)(OCH3)(2)] . DABCO . 1.66 CH2Cl2 has been developed. An one-pot reaction between the cluster precursor [Nb6Cl14(H2O)(4)] . 4H(2)O and methanol with the addition of DABCO leads to the crystallization of the title compound in high yield within a few minutes. The single-crystal X-ray structure of this cluster compound has been determined. Very strong, nearly symmetric intercluster hydrogen bonds Nb-6-MeO...H...OMe-Nb-6 are present between the cluster units. A bridging co-crystalline DABCO molecule is also involved in a three-dimensional hydrogen-bonding network. KW - Niobium KW - Cluster KW - Hydrogen Bonds KW - Synthesis KW - Structure Determination Y1 - 2021 U6 - https://doi.org/10.1002/zaac.202100138 SN - 0044-2313 SN - 1521-3749 VL - 647 IS - 18 SP - 1759 EP - 1763 PB - Wiley-VCH CY - Weinheim ER - TY - JOUR A1 - Rabe, Maximilian Michael A1 - Chandra, Johan A1 - Krügel, André A1 - Seelig, Stefan A. A1 - Vasishth, Shravan A1 - Engbert, Ralf T1 - A bayesian approach to dynamical modeling of eye-movement control in reading of normal, mirrored, and scrambled texts JF - Psychological Review N2 - In eye-movement control during reading, advanced process-oriented models have been developed to reproduce behavioral data. So far, model complexity and large numbers of model parameters prevented rigorous statistical inference and modeling of interindividual differences. Here we propose a Bayesian approach to both problems for one representative computational model of sentence reading (SWIFT; Engbert et al., Psychological Review, 112, 2005, pp. 777-813). We used experimental data from 36 subjects who read the text in a normal and one of four manipulated text layouts (e.g., mirrored and scrambled letters). The SWIFT model was fitted to subjects and experimental conditions individually to investigate between- subject variability. Based on posterior distributions of model parameters, fixation probabilities and durations are reliably recovered from simulated data and reproduced for withheld empirical data, at both the experimental condition and subject levels. A subsequent statistical analysis of model parameters across reading conditions generates model-driven explanations for observable effects between conditions. KW - reading eye movements KW - dynamical models KW - Bayesian inference KW - oculomotor KW - control KW - individual differences Y1 - 2021 U6 - https://doi.org/10.1037/rev0000268 SN - 0033-295X SN - 1939-1471 VL - 128 IS - 5 SP - 803 EP - 823 PB - American Psychological Association CY - Washington ER - TY - JOUR A1 - Macdonald, Elena A1 - Otero, Noelia A1 - Butler, Tim T1 - A comparison of long-term trends in observations and emission inventories of NOx JF - Atmospheric chemistry and physics / European Geosciences Union N2 - Air pollution is a pressing issue that is associated with adverse effects on human health, ecosystems, and climate. Despite many years of effort to improve air quality, nitrogen dioxide (NO2) limit values are still regularly exceeded in Europe, particularly in cities and along streets. This study explores how concentrations of nitrogen oxides (NOx = NO + NO2) in European urban areas have changed over the last decades and how this relates to changes in emissions. To do so, the incremental approach was used, comparing urban increments (i.e. urban background minus rural concentrations) to total emissions, and roadside increments (i.e. urban roadside concentrations minus urban background concentrations) to traffic emissions. In total, nine European cities were assessed. The study revealed that potentially confounding factors like the impact of urban pollution at rural monitoring sites through atmospheric transport are generally negligible for NOx. The approach proves therefore particularly useful for this pollutant. The estimated urban increments all showed downward trends, and for the majority of the cities the trends aligned well with the total emissions. However, it was found that factors like a very densely populated surrounding or local emission sources in the rural area such as shipping traffic on inland waterways restrict the application of the approach for some cities. The roadside increments showed an overall very diverse picture in their absolute values and trends and also in their relation to traffic emissions. This variability and the discrepancies between roadside increments and emissions could be attributed to a combination of local influencing factors at the street level and different aspects introducing inaccuracies to the trends of the emis-sion inventories used, including deficient emission factors. Applying the incremental approach was evaluated as useful for long-term pan-European studies, but at the same time it was found to be restricted to certain regions and cities due to data availability issues. The results also highlight that using emission inventories for the prediction of future health impacts and compliance with limit values needs to consider the distinct variability in the concentrations not only across but also within cities. Y1 - 2021 U6 - https://doi.org/10.5194/acp-21-4007-2021 SN - 1680-7316 SN - 1680-7324 VL - 21 IS - 5 SP - 4007 EP - 4023 PB - Copernicus CY - Göttingen ER - TY - THES A1 - Koç, Gamze T1 - A comprehensive analysis of severe flood events in Turkey T1 - Eine ausführliche Analyse schwerer Flutereignisse in der Türkei BT - event documentation, triggering mechanisms and impact modelling BT - Ereignisdokumentation, Auslösemechanismen und Auswirkungsmodellierung N2 - Over the past decades, natural hazards, many of which are aggravated by climate change and reveal an increasing trend in frequency and intensity, have caused significant human and economic losses and pose a considerable obstacle to sustainable development. Hence, dedicated action toward disaster risk reduction is needed to understand the underlying drivers and create efficient risk mitigation plans. Such action is requested by the Sendai Framework for Disaster Risk Reduction 2015-2030 (SFDRR), a global agreement launched in 2015 that establishes stating priorities for action, e.g. an improved understanding of disaster risk. Turkey is one of the SFDRR contracting countries and has been severely affected by many natural hazards, in particular earthquakes and floods. However, disproportionately little is known about flood hazards and risks in Turkey. Therefore, this thesis aims to carry out a comprehensive analysis of flood hazards for the first time in Turkey from triggering drivers to impacts. It is intended to contribute to a better understanding of flood risks, improvements of flood risk mitigation and the facilitated monitoring of progress and achievements while implementing the SFDRR. In order to investigate the occurrence and severity of flooding in comparison to other natural hazards in Turkey and provide an overview of the temporal and spatial distribution of flood losses, the Turkey Disaster Database (TABB) was examined for the years 1960-2014. The TABB database was reviewed through comparison with the Emergency Events Database (EM-DAT), the Dartmouth Flood Observatory database, the scientific literature and news archives. In addition, data on the most severe flood events between 1960 and 2014 were retrieved. These served as a basis for analyzing triggering mechanisms (i.e. atmospheric circulation and precipitation amounts) and aggravating pathways (i.e. topographic features, catchment size, land use types and soil properties). For this, a new approach was developed and the events were classified using hierarchical cluster analyses to identify the main influencing factor per event and provide additional information about the dominant flood pathways for severe floods. The main idea of the study was to start with the event impacts based on a bottom-up approach and identify the causes that created damaging events, instead of applying a model chain with long-term series as input and searching for potentially impacting events as model outcomes. However, within the frequency analysis of the flood-triggering circulation pattern types, it was discovered that events in terms of heavy precipitation were not included in the list of most severe floods, i.e. their impacts were not recorded in national and international loss databases but were mentioned in news archives and reported by the Turkish State Meteorological Service. This finding challenges bottom-up modelling approaches and underlines the urgent need for consistent event and loss documentation. Therefore, as a next step, the aim was to enhance the flood loss documentation by calibrating, validating and applying the United Nations Office for Disaster Risk Reduction (UNDRR) loss estimation method for the recent severe flood events (2015-2020). This provided, a consistent flood loss estimation model for Turkey, allowing governments to estimate losses as quickly as possible after events, e.g. to better coordinate financial aid. This thesis reveals that, after earthquakes, floods have the second most destructive effects in Turkey in terms of human and economic impacts, with over 800 fatalities and US$ 885.7 million in economic losses between 1960 and 2020, and that more attention should be paid on the national scale. The clustering results of the dominant flood-producing mechanisms (e.g. circulation pattern types, extreme rainfall, sudden snowmelt) present crucial information regarding the source and pathway identification, which can be used as base information for hazard identification in the preliminary risk assessment process. The implementation of the UNDRR loss estimation model shows that the model with country-specific parameters, calibrated damage ratios and sufficient event documentation (i.e. physically damaged units) can be recommended in order to provide first estimates of the magnitude of direct economic losses, even shortly after events have occurred, since it performed well when estimates were compared to documented losses. The presented results can contribute to improving the national disaster loss database in Turkey and thus enable a better monitoring of the national progress and achievements with regard to the targets stated by the SFDRR. In addition, the outcomes can be used to better characterize and classify flood events. Information on the main underlying factors and aggravating flood pathways further supports the selection of suitable risk reduction policies. All input variables used in this thesis were obtained from publicly available data. The results are openly accessible and can be used for further research. As an overall conclusion, it can be stated that consistent loss data collection and better event documentation should gain more attention for a reliable monitoring of the implementation of the SFDRR. Better event documentation should be established according to a globally accepted standard for disaster classification and loss estimation in Turkey. Ultimately, this enables stakeholders to create better risk mitigation actions based on clear hazard definitions, flood event classification and consistent loss estimations. N2 - In den letzten Jahrzehnten verursachten Naturgefahren hohe humanitäre und wirtschaftliche Verluste, wobei viele dieser Ereignisse durch den Klimawandel verstärkt werden und einen zunehmenden Trend in Häufigkeit und Schwere aufweisen. Daher sind gezielte Verfahren zur Reduzierung von Katastrophenrisiken erforderlich, um zugrundeliegende Treiber zu verstehen und effektive Risikominderungspläne zu erstellen. Solche Verfahren werden durch das Sendai-Rahmenwerk für Katastrophenvorsorge 2015-2030 (SFDRR) eingefordert. Das SFDRR ist, ein internationales Rahmenwerk, das 2015 verabschiedet wurde und prioritäre Maßnahmen festlegt, z.B. eine Verbesserung der Wissensgrundlagen zum Katastrophenrisiko. Die Türkei ist eines der SFDRR-Vertragsländer und wurde in der Vergangenheit von vielen Naturgefahren, insbesondere Erdbeben und Überschwemmungen schwer getroffen. Über die Hochwassergefahren und -risiken in der Türkei ist jedoch vergleichsweise wenig bekannt. In dieser Arbeit wird daher zum ersten Mal eine umfassende Analyse der Hochwassergefahren in der Türkei durchgeführt, von den auslösenden Ursachen bis hin zu den Auswirkungen. Ziel ist es, das Verständnis über Hochwasserrisiken zu verbessern, Studien zur Minderung des Hochwasserrisikos anzuregen und das Monitoring der Fortschritte und Zielerreichung bei der Umsetzung des SFDRR zu erleichtern. Um das Auftreten und die Stärke von Überschwemmungen im Vergleich zu anderen Naturgefahren in der Türkei zu untersuchen und einen Überblick über die raumzeitliche Verteilung von Hochwasserschäden, wurde die Turkey Disaster Database (TABB) für den Zeitraum 1960 bis 2014 ausgewertet. Die TABB Datenbank wurde durch Vergleiche mit der Emergency Events Datenbank (EM-DAT), der Dartmouth Flood Observatory Datenbank, wissenschaftlicher Literatur und Nachrichtenarchive überprüft. Zudem wurden die stärksten Überschwemmungen zwischen 1960 und 2014 identifiziert. Diese bildeten die Basis für eine Analyse der Auslösemechanismen (bspw. atmosphärische Zirkulationsmuster und Niederschlagsmengen) und verstärkende Wirkungspfade (z.B. topographische Eigenschaften, Größe der Einzugsgebiete, Landnutzung und Bodeneigenschaften). Dafür wurde ein neues Verfahren entwickelt, und die Ereignisse wurden mithilfe von hierarchischen Clusteranalysen klassifiziert, um die Haupteinflussfaktoren pro Ereignis zu identifizieren und zusätzliche Informationen über die dominanten Wirkungspfade bei schweren Überschwemmungen bereitzustellen. Die grundlegende Idee dieser Arbeit bestand darin, bei den Ereignisauswirkungen als Bottom-up-Ansatz zu beginnen und die Ursachen für Schadensereignisse zu identifizieren, anstatt eine Modellkette mit Langzeitreihen als Eingabe anzuwenden und darin nach potenziellen Schadensereignissen zu suchen. Bei der Häufigkeitsanalyse von hochwasserauslösenden Zirkulationsmustern wurde jedoch festgestellt, dass einige schwer Niederschlagsereignisse nicht in der Liste der schwersten Hochwasserereignisse waren, d.h., ihre Auswirkungen waren nicht in nationalen und internationalen Schadensdatenbanken dokumentiert, wurden jedoch in Nachrichtenarchiven erwähnt und vom türkischen staatlichen Wetterdienst gemeldet. Dieses Erkenntnis stellt den Bottom-up-Modelansatz in Frage und unterstreicht die Dringlichkeit einer konsistenten Ereignis- und Schadensdokumentation. Daher wurde im nächsten Schritt gezielt das Schadenmodell der Vereinten Nationen für Katastrophenvorsorge (UNDRR) für kürzlich aufgetretene starke Flutereignisse (2015-2020) angepasst, validiert und angewendet. Damit wurde ein konsistentes Hochwasserschadenmodell für die Türkei bereitgestellt, das es den Behörden ermöglicht, Verluste so schnell wie möglich nach Ereignissen abzuschätzen, zum Beispiel um eine bessere Koordination von finanziellen Hilfen zu gewährleisten. Diese Arbeit zeigt, dass Überschwemmungen mit mehr als 800 Todesfällen und 885,7 Millionen US Dollar wirtschaftlichen Schaden zwischen 1960 und 2020 nach Erdbeben den zweit höchsten zerstörerischen Effekt in der Türkei in Bezug auf humanitäre und wirtschaftliche Auswirkungen haben. Daher sollte dieses Thema mehr Aufmerksamkeit auf nationaler Ebene erhalten. Die Cluster-Ergebnisse der dominanten hochwasser-auslösenden Mechanismen (z.B. Zirkulationsmuster, Starkniederschlag, plötzliche Schneeschmelze) erhalten wichtige Informationen zur Quell- und Pfad-Identifikation, welche als Basisinformation für Gefahren-identifikation in der vorläufigen Risikoeinschätzung dienen kann. Die Implementierung des UNDRR-Schadenmodells zeigt, dass das Modell mit länderspezifischen Parametern, kalibrierten Schadensgraden und ausreichender Ereignisdokumentation (d.h. physischer geschädigte Einheiten) empfohlen werden kann, um erste Schätzungen zur Höhe der direkten wirtschaftlichen Schäden bereitzustellen -- auch unmittelbar nach Eintreten von Ereignissen, da die Modellschätzungen im Vergleich mit dokumentierten Verlusten gut übereinstimmten. Die präsentierten Ergebnisse können dazu beitragen, die nationale Schadensdatenbank der Türkei zu verbessern, und somit ein besseres Monitoring der nationalen Fortschritte und Erfolge im Hinblick auf die Ziele des SFDRR ermöglichen. Zusätzlich können die Ergebnisse für eine bessere Charakterisierung und Klassifizierung von Hochwasserereignissen verwendet werden. Informationen zu den zugrundeliegenden Einflussfaktoren und verstärkenden Wirkungspfaden unterstützen die Auswahl geeigneter Risikomanagementstrategien. Alle Eingabevariablen dieser Arbeit wurden aus öffentlich verfügbaren Daten bezogen. Die Ergebnisse sind zugänglich und können für die weitere Forschung verwendet werden. Insgesamt konnte festgestellt werden, dass die konsistente Erfassung von Schadensdaten und eine bessere Ereignisdokumentation mehr Beachtung finden muss, um die Implementierung des SFDRR verlässlich zu überwachen. Bessere Ereignisdokumentationen sollten nach einem weltweit anerkannten Standard für Gefahrenklassifizierung und Schadensabschätzung in der Türkei etabliert werden. Letztendlich ermöglicht dies den Verantwortlichen auf Basis von eindeutigen Gefahrendefinitionen, Hochwasser-Ereignisklassifizierungen und konsistenten Schadenschätzungen bessere Maßnahmen zur Risikominderung zu erarbeiten. KW - Flood hazards KW - Turkey KW - Triggering mechanisms KW - Cluster analysis KW - Hochwassergefahren KW - Türkei KW - Auslösemechanismen KW - Clusteranalyse KW - Impact modelling KW - Schadenmodell Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-517853 ER - TY - CHAP A1 - Thim, Christof A1 - Grum, Marcus A1 - Schüffler, Arnulf A1 - Roling, Wiebke A1 - Kluge, Annette A1 - Gronau, Norbert ED - Andersen, Ann-Louise ED - Andersen, Rasmus ED - Brunoe, Thomas Ditlev ED - Larsen, Maria Stoettrup Schioenning ED - Nielsen, Kjeld ED - Napoleone, Alessia ED - Kjeldgaard, Stefan T1 - A concept for a distributed Interchangeable knowledge base in CPPS T2 - Towards sustainable customization: cridging smart products and manufacturing systems N2 - As AI technology is increasingly used in production systems, different approaches have emerged from highly decentralized small-scale AI at the edge level to centralized, cloud-based services used for higher-order optimizations. Each direction has disadvantages ranging from the lack of computational power at the edge level to the reliance on stable network connections with the centralized approach. Thus, a hybrid approach with centralized and decentralized components that possess specific abilities and interact is preferred. However, the distribution of AI capabilities leads to problems in self-adapting learning systems, as knowledgebases can diverge when no central coordination is present. Edge components will specialize in distinctive patterns (overlearn), which hampers their adaptability for different cases. Therefore, this paper aims to present a concept for a distributed interchangeable knowledge base in CPPS. The approach is based on various AI components and concepts for each participating node. A service-oriented infrastructure allows a decentralized, loosely coupled architecture of the CPPS. By exchanging knowledge bases between nodes, the overall system should become more adaptive, as each node can “forget” their present specialization. KW - learning KW - distributed knowledge base KW - artificial intelligence KW - CPPS Y1 - 2021 SN - 978-3-030-90699-3 SN - 978-3-030-90702-0 SN - 978-3-030-90700-6 U6 - https://doi.org/10.1007/978-3-030-90700-6_35 SP - 314 EP - 321 PB - Springer CY - Cham ER - TY - JOUR A1 - Wolff, Martin A1 - Gast, Klaus A1 - Evers, Andreas A1 - Kurz, Michael A1 - Pfeiffer-Marek, Stefania A1 - Schüler, Anja A1 - Seckler, Robert A1 - Thalhammer, Anja T1 - A Conserved Hydrophobic Moiety and Helix-Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4 JF - Biomolecules N2 - Exendin-4 is a pharmaceutical peptide used in the control of insulin secretion. Structural information on exendin-4 and related peptides especially on the level of quaternary structure is scarce. We present the first published association equilibria of exendin-4 directly measured by static and dynamic light scattering. We show that exendin-4 oligomerization is pH dependent and that these oligomers are of low compactness. We relate our experimental results to a structural hypothesis to describe molecular details of exendin-4 oligomers. Discussion of the validity of this hypothesis is based on NMR, circular dichroism and fluorescence spectroscopy, and light scattering data on exendin-4 and a set of exendin-4 derived peptides. The essential forces driving oligomerization of exendin-4 are helix–helix interactions and interactions of a conserved hydrophobic moiety. Our structural hypothesis suggests that key interactions of exendin-4 monomers in the experimentally supported trimer take place between a defined helical segment and a hydrophobic triangle constituted by the Phe22 residues of the three monomeric subunits. Our data rationalize that Val19 might function as an anchor in the N-terminus of the interacting helix-region and that Trp25 is partially shielded in the oligomer by C-terminal amino acids of the same monomer. Our structural hypothesis suggests that the Trp25 residues do not interact with each other, but with C-terminal Pro residues of their own monomers. KW - biophysics KW - diabetes KW - peptides KW - oligomerization KW - conformational change KW - molecular modeling KW - static and dynamic light scattering KW - spectroscopy Y1 - 2021 U6 - https://doi.org/10.3390/biom11091305 SN - 2218-273X VL - 11 IS - 9 PB - MDPI CY - Basel ER - TY - GEN A1 - Wolff, Martin A1 - Gast, Klaus A1 - Evers, Andreas A1 - Kurz, Michael A1 - Pfeiffer-Marek, Stefania A1 - Schüler, Anja A1 - Seckler, Robert A1 - Thalhammer, Anja T1 - A Conserved Hydrophobic Moiety and Helix-Helix Interactions Drive the Self-Assembly of the Incretin Analog Exendin-4 T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Exendin-4 is a pharmaceutical peptide used in the control of insulin secretion. Structural information on exendin-4 and related peptides especially on the level of quaternary structure is scarce. We present the first published association equilibria of exendin-4 directly measured by static and dynamic light scattering. We show that exendin-4 oligomerization is pH dependent and that these oligomers are of low compactness. We relate our experimental results to a structural hypothesis to describe molecular details of exendin-4 oligomers. Discussion of the validity of this hypothesis is based on NMR, circular dichroism and fluorescence spectroscopy, and light scattering data on exendin-4 and a set of exendin-4 derived peptides. The essential forces driving oligomerization of exendin-4 are helix–helix interactions and interactions of a conserved hydrophobic moiety. Our structural hypothesis suggests that key interactions of exendin-4 monomers in the experimentally supported trimer take place between a defined helical segment and a hydrophobic triangle constituted by the Phe22 residues of the three monomeric subunits. Our data rationalize that Val19 might function as an anchor in the N-terminus of the interacting helix-region and that Trp25 is partially shielded in the oligomer by C-terminal amino acids of the same monomer. Our structural hypothesis suggests that the Trp25 residues do not interact with each other, but with C-terminal Pro residues of their own monomers. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1161 KW - biophysics KW - diabetes KW - peptides KW - oligomerization KW - conformational change KW - molecular modeling KW - static and dynamic light scattering KW - spectroscopy Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-522081 SN - 1866-8372 IS - 9 ER - TY - JOUR A1 - Cvetković, Nada A1 - Conrad, Tim A1 - Lie, Han Cheng T1 - A convergent discretization method for transition path theory for diffusion processes JF - Multiscale modeling & simulation : a SIAM interdisciplinary journal N2 - Transition path theory (TPT) for diffusion processes is a framework for analyzing the transitions of multiscale ergodic diffusion processes between disjoint metastable subsets of state space. Most methods for applying TPT involve the construction of a Markov state model on a discretization of state space that approximates the underlying diffusion process. However, the assumption of Markovianity is difficult to verify in practice, and there are to date no known error bounds or convergence results for these methods. We propose a Monte Carlo method for approximating the forward committor, probability current, and streamlines from TPT for diffusion processes. Our method uses only sample trajectory data and partitions of state space based on Voronoi tessellations. It does not require the construction of a Markovian approximating process. We rigorously prove error bounds for the approximate TPT objects and use these bounds to show convergence to their exact counterparts in the limit of arbitrarily fine discretization. We illustrate some features of our method by application to a process that solves the Smoluchowski equation on a triple-well potential. KW - ergodic diffusion processes KW - transition paths KW - rare events KW - Monte Carlo KW - methods Y1 - 2021 U6 - https://doi.org/10.1137/20M1329354 SN - 1540-3459 SN - 1540-3467 VL - 19 IS - 1 SP - 242 EP - 266 PB - Society for Industrial and Applied Mathematics CY - Philadelphia ER - TY - JOUR A1 - Buyinza, Daniel A1 - Derese, Solomon A1 - Ndakala, Albert A1 - Heydenreich, Matthias A1 - Yenesew, Abiy A1 - Koch, Andreas A1 - Oriko, Richard T1 - A coumestan and a coumaronochromone from Millettia lasiantha JF - Biochemical systematics and ecology N2 - The manuscript describes the phytochemical investigation of the roots, leaves and stem bark of Millettia lasiantha resulting in the isolation of twelve compounds including two new isomeric isoflavones lascoumestan and las-coumaronochromone. The structures of the new compounds were determined using different spectroscopic techniques. KW - Millettia lasiantha KW - Leguminosae KW - Coumestan KW - Coumaronochromone Y1 - 2021 U6 - https://doi.org/10.1016/j.bse.2021.104277 SN - 0305-1978 SN - 1873-2925 VL - 97 PB - Elsevier CY - Oxford ER - TY - JOUR A1 - Trindade, Inês T1 - A drop of immunity JF - Molecular plant Y1 - 2021 U6 - https://doi.org/10.1016/j.molp.2021.07.022 SN - 1674-2052 SN - 1752-9867 VL - 14 IS - 9 SP - 1437 EP - 1438 PB - Oxford Univ. Press CY - Oxford ER - TY - JOUR A1 - Ette, Ottmar T1 - A expulsão do Éden BT - Migração e escrita depois do paraíso JF - Literatura e autoritarismo N2 - A temática da migração está intimamente vinculada à história humana, desde a narrativa bíblica da expulsão do paraíso. O ser humano não apenas empregou técnicas cada vez mais sofisticadas para a violência, como também transmitiu, através dos séculos, técnicas de conservação e uso de seu saberconviver. Nesse sentido móvel da história, e em consonância com as literaturas do mundo, a partir de suas diversas origens, é possível dizer que existe um “Homo migrans” desde que existe o “Homo sapiens”. Assim, é possível afirmar que as ideias territoriais ou territorializantes com proveniência histórico-espacial permitem, vez ou outra, reconhecer seus esforços para filtrar e isolar a dimensão histórico-móvel e vetorial da história como narrativa, para tentar construir, com a ajuda de ideias estáticas, novos lugares da promessa ou da perda, da abundância ou da queda. KW - Migração KW - Saberconviver KW - Literaturas do mundo Y1 - 2021 U6 - https://doi.org/10.5902/1679849X65745 SN - 1679-849X IS - 25 SP - 5 EP - 42 PB - Universidade Federal de Santa Maria (UFSM) CY - Santa Maria ER - TY - JOUR A1 - Thomas, Timon A1 - Pfrommer, Christoph A1 - Pakmor, Rüdiger T1 - A finite volume method for two-moment cosmic ray hydrodynamics on a moving mesh JF - Monthly notices of the Royal Astronomical Society N2 - We present a new numerical algorithm to solve the recently derived equations of two-moment cosmic ray hydrodynamics (CRHD). The algorithm is implemented as a module in the moving mesh AREPO code. Therein, the anisotropic transport of cosmic rays (CRs) along magnetic field lines is discretized using a path-conservative finite volume method on the unstructured time-dependent Voronoi mesh of AREPO. The interaction of CRs and gyroresonant Alfven waves is described by short time-scale source terms in the CRHD equations. We employ a custom-made semi-implicit adaptive time stepping source term integrator to accurately integrate this interaction on the small light-crossing time of the anisotropic transport step. Both the transport and the source term integration step are separated from the evolution of the magnetohydrodynamical equations using an operator split approach. The new algorithm is tested with a variety of test problems, including shock tubes, a perpendicular magnetized discontinuity, the hydrodynamic response to a CR overpressure, CR acceleration of a warm cloud, and a CR blast wave, which demonstrate that the coupling between CR and magnetohydrodynamics is robust and accurate. We demonstrate the numerical convergence of the presented scheme using new linear and non-linear analytic solutions. KW - hydrodynamics KW - MHD KW - methods: numerical KW - cosmic rays Y1 - 2021 U6 - https://doi.org/10.1093/mnras/stab397 SN - 0035-8711 SN - 1365-2966 VL - 503 IS - 2 SP - 2242 EP - 2264 PB - Oxford University Press CY - Oxford ER - TY - JOUR A1 - Kreowsky, Philipp A1 - Stabernack, Christian Benno T1 - A full-featured FPGA-based pipelined architecture for SIFT extraction JF - IEEE access : practical research, open solutions / Institute of Electrical and Electronics Engineers N2 - Image feature detection is a key task in computer vision. Scale Invariant Feature Transform (SIFT) is a prevalent and well known algorithm for robust feature detection. However, it is computationally demanding and software implementations are not applicable for real-time performance. In this paper, a versatile and pipelined hardware implementation is proposed, that is capable of computing keypoints and rotation invariant descriptors on-chip. All computations are performed in single precision floating-point format which makes it possible to implement the original algorithm with little alteration. Various rotation resolutions and filter kernel sizes are supported for images of any resolution up to ultra-high definition. For full high definition images, 84 fps can be processed. Ultra high definition images can be processed at 21 fps. KW - Field programmable gate arrays KW - Convolution KW - Signal processing KW - algorithms KW - Kernel KW - Image resolution KW - Histograms KW - Feature extraction KW - Scale-invariant feature transform (SIFT) KW - field-programmable gate array KW - (FPGA) KW - image processing KW - computer vision KW - parallel processing KW - architecture KW - real-time KW - hardware architecture Y1 - 2021 U6 - https://doi.org/10.1109/ACCESS.2021.3104387 SN - 2169-3536 VL - 9 SP - 128564 EP - 128573 PB - Inst. of Electr. and Electronics Engineers CY - New York, NY ER - TY - JOUR A1 - Gerstenberg, Annette A1 - Skupien-Dekens, Carine T1 - A grammar of authority? BT - directive Speech Acts and terms of address in two single-genre corpora of Classical French JF - Journal of historical pragmatics N2 - Directive Speech Acts (dsas) are a major feature of historical pragmatics, specifically in research on historical (im)politeness. However, for Classical French, there is a lack of research on related phenomena. In our contribution, we present two recently constructed corpora covering the period of Classical French, sermo and apwcf. We present these corpora in terms of their genre characteristics on a communicative-functional and socio-pragmatic level. Based on the observation that, both in sermo and apwcf, dsas frequently occur together with terms of address, we analyse and manually code a sample based on this co-occurrence, and we compare the results with regard to special features in the individual corpora. The emerging patterns show a clear correspondence between socio-pragmatic factors and the linguistic means used to realise dsas. We propose that these results can be interpreted as signs of an underlying "grammar of authority". KW - corpus KW - correspondence KW - directive speech acts KW - politeness KW - sermons KW - terms of address Y1 - 2021 U6 - https://doi.org/10.1075/jhp.17006.ger SN - 1566-5852 SN - 1569-9854 VL - 22 IS - 1 SP - 1 EP - 33 PB - John Benjamins Publishing Co. CY - Amsterdam ER - TY - JOUR A1 - Kempton, Mark A1 - Münch, Florentin A1 - Yau, Shing-Tung T1 - A homology vanishing theorem for graphs with positive curvature JF - Communications in analysis and geometry N2 - We prove a homology vanishing theorem for graphs with positive Bakry-' Emery curvature, analogous to a classic result of Bochner on manifolds [3]. Specifically, we prove that if a graph has positive curvature at every vertex, then its first homology group is trivial, where the notion of homology that we use for graphs is the path homology developed by Grigor'yan, Lin, Muranov, and Yau [11]. We moreover prove that the fundamental group is finite for graphs with positive Bakry-' Emery curvature, analogous to a classic result of Myers on manifolds [22]. The proofs draw on several separate areas of graph theory, including graph coverings, gain graphs, and cycle spaces, in addition to the Bakry-Emery curvature, path homology, and graph homotopy. The main results follow as a consequence of several different relationships developed among these different areas. Specifically, we show that a graph with positive curvature cannot have a non-trivial infinite cover preserving 3-cycles and 4-cycles, and give a combinatorial interpretation of the first path homology in terms of the cycle space of a graph. Furthermore, we relate gain graphs to graph homotopy and the fundamental group developed by Grigor'yan, Lin, Muranov, and Yau [12], and obtain an alternative proof of their result that the abelianization of the fundamental group of a graph is isomorphic to the first path homology over the integers. Y1 - 2021 UR - https://www.intlpress.com/site/pub/files/_fulltext/journals/cag/2021/0029/0006/CAG-2021-0029-0006-a005.pdf U6 - https://doi.org/10.4310/CAG.2021.v29.n6.a5 SN - 1019-8385 SN - 1944-9992 VL - 29 IS - 6 SP - 1449 EP - 1473 PB - International Press of Boston CY - Somerville ER - TY - JOUR A1 - Klemme, Stephan A1 - Feldhaus, Michael A1 - Potapkin, Vasily A1 - Wilke, Max A1 - Borchert, Manuela A1 - Louvel, Marion A1 - Loges, Anselm A1 - Rohrbach, Arno A1 - Weitkamp, Petra A1 - Welter, Edmund A1 - Kokh, Maria A. A1 - Schmidt, Christian A1 - Testemale, Denis T1 - A hydrothermal apparatus for x-ray absorption spectroscopy of hydrothermal fluids at DESY JF - Review of scientific instruments : a monthly journal devoted to scientific instruments, apparatus, and techniques N2 - We present a new autoclave that enables in situ characterization of hydrothermal fluids at high pressures and high temperatures at synchrotron x-ray radiation sources. The autoclave has been specifically designed to enable x-ray absorption spectroscopy in fluids with applications to mineral solubility and element speciation analysis in hydrothermal fluids in complex compositions. However, other applications, such as Raman spectroscopy, in high-pressure fluids are also possible with the autoclave. First experiments were run at pressures between 100 and 600 bars and at temperatures between 25 degrees C and 550 degrees C, and preliminary results on scheelite dissolution in fluids of different compositions show that the autoclave is well suited to study the behavior of ore-forming metals at P-T conditions relevant to the Earth's crust. Y1 - 2021 U6 - https://doi.org/10.1063/5.0044767 SN - 0034-6748 SN - 1089-7623 VL - 92 IS - 6 PB - AIP Publishing CY - Melville ER - TY - JOUR A1 - Kosman, Admiʾel T1 - A Journey Through the Gates of Good and Evil in Jewish Sources BT - towards a Monistic-Psychological reading of the Azazel Ritual JF - Zeramim : an Online Journal of Applied Jewish Thought Y1 - 2021 UR - https://zeramim.org/past-issues/vol-v-issue-2-spring2021-5781/a-journey-through-the-gates-of-good-and-evilin-jewish-sources-towards-a-monistic-psychological-reading-of-the-azazel-ritual/ SN - 2577-4921 VL - V IS - 2 ER - TY - JOUR A1 - Mösenlechner, Gerald A1 - Paunzen, Ernst A1 - Pelisoli, Ingrid D. A1 - Seelig, Joseph A1 - Stidl, Sarah A1 - Maitzen, Hans Michael T1 - A Kepler K2 view of subdwarf A-type stars JF - Astronomy and astrophysics : an international weekly journal N2 - Context. The spectroscopic class of subdwarf A-type (sdA) stars has come into focus in recent years because of their possible link to extremely low-mass white dwarfs, a rare class of objects resulting from binary evolution. Although most sdA stars are consistent with metal-poor halo main-sequence stars, the formation and evolution of a fraction of these stars are still matters of debate. Aims. The identification of photometric variability can help to put further constraints on the evolutionary status of sdA stars, in particular through the analysis of pulsations. Moreover, the binary ratio, which can be deduced from eclipsing binaries and ellipsoidal variables, is important as input for stellar models. In order to search for variability due to either binarity or pulsations in objects of the spectroscopic sdA class, we have extracted all available high precision light curves from the Kepler K2 mission. Methods. We have performed a thorough time series analysis on all available light curves, employing three different methods. Frequencies with a signal-to-noise ratio higher than four have been used for further analysis. Results. From the 25 targets, 13 turned out to be variables of different kinds (i.e., classical pulsating stars, ellipsoidal and cataclysmic variables, eclipsing binaries, and rotationally induced variables). For the remaining 12 objects, a variability threshold was determined. KW - subdwarfs KW - white dwarfs KW - binaries: general KW - stars: evolution KW - stars: variables: general Y1 - 2022 U6 - https://doi.org/10.1051/0004-6361/202037789 SN - 0004-6361 SN - 1432-0746 VL - 657 PB - EDP Sciences CY - Les Ulis ER - TY - JOUR A1 - Schwarz, Ingo A1 - Kutzinski, Vera M. ED - Ette, Ottmar ED - Knobloch, Eberhard T1 - A Letter from Alexander von Humboldt to Joseph Albert Wright – Archival Traces JF - HiN : Alexander von Humboldt im Netz N2 - A few months before his death, A. v. Humboldt attended the celebration in honor of the 127th birthday of George Washington at the US legation in Berlin. A letter to the American Envoy, Joseph A. Wright (1810 – 1867), underlines Humboldt’s admiration for the fi rst president of the United States. At the same time Humboldt asked the diplomat to mail a letter to the German-American Bernard Moses (1832 – 1897) in Clinton, Louisiana, who had named his son Alexander Humboldt Moses (grave on the Hebrew Rest Cemetery #2 in New Orleans, burial plot A, 12, 5). It appears to be possible that the Moses family still owns Humboldt’s letter. N2 - Wenige Monate vor seinem Tod besuchte A. v. Humboldt die Feier zu Ehren des 127. Geburtstages von George Washington an der Gesandtschaft der Vereinigten Staaten in Berlin. Ein Brief an den Gesandten, Joseph A. Wright (1810 – 1867), betonte Humboldts Bewunderung für den ersten Präsidenten der Vereinten Staaten. Gleichzeit bat Humboldt den Diplomaten um die Beförderung eines Briefes an den Deutschamerikaner Bernard Moses(1832 – 1897) in Clinton, Louisiana, der seinen Sohn Alexander Humboldt Moses (Grab auf dem Hebrew Rest Cemetery #2 in New Orleans, Grabstelle A, 12, 5) genannt hat. N2 - Unos meses antes de su muerte, A. v. Humboldt asistió a la celebración en honor al 127º cumpleaños de George Washington en la legación estadounidense en Berlín. Una carta al delegado estadounidense, Joseph A. Wright (1810 – 1867), subraya la admiración de Humboldt por el primer presidente de los Estados Unidos. Al mismo tiempo, Humboldt le pidió al diplomático que enviara una carta al germano-estadounidense Bernard Moses (1832 – 1897) en Clinton, Louisiana, quien había puesto a su hijo, el nombre de Alexander Humboldt Moses(tumba en el cementerio Hebrew Rest número 2 en Nueva Orleans, lugar de enteramiento: A, 12, 5). KW - Alexander Humboldt KW - Moses KW - Korrespondenz Alexander von Humboldts KW - Vereinigten Staaten Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-532787 SN - 2568-3543 SN - 1617-5239 VL - XXII IS - 43 SP - 5 EP - 12 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - JOUR A1 - Schneider, Sven A1 - Lambers, Leen A1 - Orejas, Fernando T1 - A logic-based incremental approach to graph repair featuring delta preservation JF - International journal on software tools for technology transfer : STTT N2 - We introduce a logic-based incremental approach to graph repair, generating a sound and complete (upon termination) overview of least-changing graph repairs from which a user may select a graph repair based on non-formalized further requirements. This incremental approach features delta preservation as it allows to restrict the generation of graph repairs to delta-preserving graph repairs, which do not revert the additions and deletions of the most recent consistency-violating graph update. We specify consistency of graphs using the logic of nested graph conditions, which is equivalent to first-order logic on graphs. Technically, the incremental approach encodes if and how the graph under repair satisfies a graph condition using the novel data structure of satisfaction trees, which are adapted incrementally according to the graph updates applied. In addition to the incremental approach, we also present two state-based graph repair algorithms, which restore consistency of a graph independent of the most recent graph update and which generate additional graph repairs using a global perspective on the graph under repair. We evaluate the developed algorithms using our prototypical implementation in the tool AutoGraph and illustrate our incremental approach using a case study from the graph database domain. KW - Nested graph conditions KW - Graph repair KW - Model repair KW - Consistency KW - restoration KW - Delta preservation KW - Graph databases KW - Model-driven KW - engineering Y1 - 2021 U6 - https://doi.org/10.1007/s10009-020-00584-x SN - 1433-2779 SN - 1433-2787 VL - 23 IS - 3 SP - 369 EP - 410 PB - Springer CY - Berlin ; Heidelberg ER - TY - JOUR A1 - Fuchs, Susanne A1 - Koenig, Laura L. A1 - Gerstenberg, Annette T1 - A longitudinal study of speech acoustics in older French females BT - analysis of the filler particle euh across utterance positions JF - Languages : open access journal N2 - Aging in speech production is a multidimensional process. Biological, cognitive, social, and communicative factors can change over time, stay relatively stable, or may even compensate for each other. In this longitudinal work, we focus on stability and change at the laryngeal and supralaryngeal levels in the discourse particle euh produced by 10 older French-speaking females at two times, 10 years apart. Recognizing the multiple discourse roles of euh, we divided out occurrences according to utterance position. We quantified the frequency of euh, and evaluated acoustic changes in formants, fundamental frequency, and voice quality across time and utterance position. Results showed that euh frequency was stable with age. The only acoustic measure that revealed an age effect was harmonics-to-noise ratio, showing less noise at older ages. Other measures mostly varied with utterance position, sometimes in interaction with age. Some voice quality changes could reflect laryngeal adjustments that provide for airflow conservation utterance-finally. The data suggest that aging effects may be evident in some prosodic positions (e.g., utterance-final position), but not others (utterance-initial position). Thus, it is essential to consider the interactions among these factors in future work and not assume that vocal aging is evident throughout the signal. KW - aging KW - prosody KW - voice quality KW - fundamental frequency KW - formants KW - filler KW - particles Y1 - 2021 U6 - https://doi.org/10.3390/languages6040211 SN - 2226-471X VL - 6 IS - 4 PB - MDPI CY - Basel ER - TY - JOUR A1 - Wandt, Viktoria Klara Veronika A1 - Winkelbeiner, Nicola Lisa A1 - Bornhorst, Julia A1 - Witt, Barbara A1 - Raschke, Stefanie A1 - Simon, Luise A1 - Ebert, Franziska A1 - Kipp, Anna Patricia A1 - Schwerdtle, Tanja T1 - A matter of concern BT - trace element dyshomeostasis and genomic stability in neurons JF - Redox Biology N2 - Neurons are post-mitotic cells in the brain and their integrity is of central importance to avoid neurodegeneration. Yet, the inability of self-replenishment of post-mitotic cells results in the need to withstand challenges from numerous stressors during life. Neurons are exposed to oxidative stress due to high oxygen consumption during metabolic activity in the brain. Accordingly, DNA damage can occur and accumulate, resulting in genome instability. In this context, imbalances in brain trace element homeostasis are a matter of concern, especially regarding iron, copper, manganese, zinc, and selenium. Although trace elements are essential for brain physiology, excess and deficient conditions are considered to impair neuronal maintenance. Besides increasing oxidative stress, DNA damage response and repair of oxidative DNA damage are affected by trace elements. Hence, a balanced trace element homeostasis is of particular importance to safeguard neuronal genome integrity and prevent neuronal loss. This review summarises the current state of knowledge on the impact of deficient, as well as excessive iron, copper, manganese, zinc, and selenium levels on neuronal genome stability Y1 - 2021 U6 - https://doi.org/10.1016/j.redox.2021.101877 VL - 41 PB - Elsevier CY - Amsterdam ER - TY - RPRT A1 - Šedová, Barbora A1 - Čizmaziová, Lucia A1 - Cook, Athene T1 - A meta-analysis of climate migration literature T2 - CEPA Discussion Papers N2 - The large literature that aims to find evidence of climate migration delivers mixed findings. This meta-regression analysis i) summarizes direct links between adverse climatic events and migration, ii) maps patterns of climate migration, and iii) explains the variation in outcomes. Using a set of limited dependent variable models, we meta-analyze thus-far the most comprehensive sample of 3,625 estimates from 116 original studies and produce novel insights on climate migration. We find that extremely high temperatures and drying conditions increase migration. We do not find a significant effect of sudden-onset events. Climate migration is most likely to emerge due to contemporaneous events, to originate in rural areas and to take place in middle-income countries, internally, to cities. The likelihood to become trapped in affected areas is higher for women and in low-income countries, particularly in Africa. We uniquely quantify how pitfalls typical for the broader empirical climate impact literature affect climate migration findings. We also find evidence of different publication biases. T3 - CEPA Discussion Papers - 29 KW - migration KW - climate change KW - meta-analysis Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-499827 SN - 2628-653X IS - 29 ER - TY - THES A1 - Andjelkovic, Marko T1 - A methodology for characterization, modeling and mitigation of single event transient effects in CMOS standard combinational cells T1 - Eine Methode zur Charakterisierung, Modellierung und Minderung von SET Effekten in kombinierten CMOS-Standardzellen N2 - With the downscaling of CMOS technologies, the radiation-induced Single Event Transient (SET) effects in combinational logic have become a critical reliability issue for modern integrated circuits (ICs) intended for operation under harsh radiation conditions. The SET pulses generated in combinational logic may propagate through the circuit and eventually result in soft errors. It has thus become an imperative to address the SET effects in the early phases of the radiation-hard IC design. In general, the soft error mitigation solutions should accommodate both static and dynamic measures to ensure the optimal utilization of available resources. An efficient soft-error-aware design should address synergistically three main aspects: (i) characterization and modeling of soft errors, (ii) multi-level soft error mitigation, and (iii) online soft error monitoring. Although significant results have been achieved, the effectiveness of SET characterization methods, accuracy of predictive SET models, and efficiency of SET mitigation measures are still critical issues. Therefore, this work addresses the following topics: (i) Characterization and modeling of SET effects in standard combinational cells, (ii) Static mitigation of SET effects in standard combinational cells, and (iii) Online particle detection, as a support for dynamic soft error mitigation. Since the standard digital libraries are widely used in the design of radiation-hard ICs, the characterization of SET effects in standard cells and the availability of accurate SET models for the Soft Error Rate (SER) evaluation are the main prerequisites for efficient radiation-hard design. This work introduces an approach for the SPICE-based standard cell characterization with the reduced number of simulations, improved SET models and optimized SET sensitivity database. It has been shown that the inherent similarities in the SET response of logic cells for different input levels can be utilized to reduce the number of required simulations. Based on characterization results, the fitting models for the SET sensitivity metrics (critical charge, generated SET pulse width and propagated SET pulse width) have been developed. The proposed models are based on the principle of superposition, and they express explicitly the dependence of the SET sensitivity of individual combinational cells on design, operating and irradiation parameters. In contrast to the state-of-the-art characterization methodologies which employ extensive look-up tables (LUTs) for storing the simulation results, this work proposes the use of LUTs for storing the fitting coefficients of the SET sensitivity models derived from the characterization results. In that way the amount of characterization data in the SET sensitivity database is reduced significantly. The initial step in enhancing the robustness of combinational logic is the application of gate-level mitigation techniques. As a result, significant improvement of the overall SER can be achieved with minimum area, delay and power overheads. For the SET mitigation in standard cells, it is essential to employ the techniques that do not require modifying the cell structure. This work introduces the use of decoupling cells for improving the robustness of standard combinational cells. By insertion of two decoupling cells at the output of a target cell, the critical charge of the cell’s output node is increased and the attenuation of short SETs is enhanced. In comparison to the most common gate-level techniques (gate upsizing and gate duplication), the proposed approach provides better SET filtering. However, as there is no single gate-level mitigation technique with optimal performance, a combination of multiple techniques is required. This work introduces a comprehensive characterization of gate-level mitigation techniques aimed to quantify their impact on the SET robustness improvement, as well as introduced area, delay and power overhead per gate. By characterizing the gate-level mitigation techniques together with the standard cells, the required effort in subsequent SER analysis of a target design can be reduced. The characterization database of the hardened standard cells can be utilized as a guideline for selection of the most appropriate mitigation solution for a given design. As a support for dynamic soft error mitigation techniques, it is important to enable the online detection of energetic particles causing the soft errors. This allows activating the power-greedy fault-tolerant configurations based on N-modular redundancy only at the high radiation levels. To enable such a functionality, it is necessary to monitor both the particle flux and the variation of particle LET, as these two parameters contribute significantly to the system SER. In this work, a particle detection approach based on custom-sized pulse stretching inverters is proposed. Employing the pulse stretching inverters connected in parallel enables to measure the particle flux in terms of the number of detected SETs, while the particle LET variations can be estimated from the distribution of SET pulse widths. This approach requires a purely digital processing logic, in contrast to the standard detectors which require complex mixed-signal processing. Besides the possibility of LET monitoring, additional advantages of the proposed particle detector are low detection latency and power consumption, and immunity to error accumulation. The results achieved in this thesis can serve as a basis for establishment of an overall soft-error-aware database for a given digital library, and a comprehensive multi-level radiation-hard design flow that can be implemented with the standard IC design tools. The following step will be to evaluate the achieved results with the irradiation experiments. N2 - Mit der Verkleinerung der Strukturen moderner CMOS-Technologien sind strahlungsinduzierte Single Event Transient (SET)-Effekte in kombinatorischer Logik zu einem kritischen Zuverlässigkeitsproblem in integrierten Schaltkreisen (ICs) geworden, die für den Betrieb unter rauen Strahlungsbedingungen (z. B. im Weltraum) vorgesehen sind. Die in der Kombinationslogik erzeugten SET-Impulse können durch die Schaltungen propagieren und schließlich in Speicherelementen (z.B. Flip-Flops oder Latches) zwischengespeichert werden, was zu sogenannten Soft-Errors und folglich zu Datenbeschädigungen oder einem Systemausfall führt. Daher ist es in den frühen Phasen des strahlungsharten IC-Designs unerlässlich geworden, die SET-Effekte systematisch anzugehen. Im Allgemeinen sollten die Lösungen zur Minderung von Soft-Errors sowohl statische als auch dynamische Maßnahmen berücksichtigen, um die optimale Nutzung der verfügbaren Ressourcen sicherzustellen. Somit sollte ein effizientes Soft-Error-Aware-Design drei Hauptaspekte synergistisch berücksichtigen: (i) die Charakterisierung und Modellierung von Soft-Errors, (ii) eine mehrstufige-Soft-Error-Minderung und (iii) eine Online-Soft-Error-Überwachung. Obwohl signifikante Ergebnisse erzielt wurden, sind die Wirksamkeit der SET-Charakterisierung, die Genauigkeit von Vorhersagemodellen und die Effizienz der Minderungsmaßnahmen immer noch die kritischen Punkte. Daher stellt diese Arbeit die folgenden Originalbeiträge vor: • Eine ganzheitliche Methodik zur SPICE-basierten Charakterisierung von SET-Effekten in kombinatorischen Standardzellen und entsprechenden Härtungskonfigurationen auf Gate-Ebene mit reduzierter Anzahl von Simulationen und reduzierter SET-Sensitivitätsdatenbank. • Analytische Modelle für SET-Empfindlichkeit (kritische Ladung, erzeugte SET-Pulsbreite und propagierte SET-Pulsbreite), basierend auf dem Superpositionsprinzip und Anpassung der Ergebnisse aus SPICE-Simulationen. • Ein Ansatz zur SET-Abschwächung auf Gate-Ebene, der auf dem Einfügen von zwei Entkopplungszellen am Ausgang eines Logikgatters basiert, was den Anstieg der kritischen Ladung und die signifikante Unterdrückung kurzer SETs beweist. • Eine vergleichende Charakterisierung der vorgeschlagenen SET-Abschwächungstechnik mit Entkopplungszellen und sieben bestehenden Techniken durch eine quantitative Bewertung ihrer Auswirkungen auf die Verbesserung der SET-Robustheit einzelner Logikgatter. • Ein Partikeldetektor auf Basis von Impulsdehnungs-Invertern in Skew-Größe zur Online-Überwachung des Partikelflusses und der LET-Variationen mit rein digitaler Anzeige. Die in dieser Dissertation erzielten Ergebnisse können als Grundlage für den Aufbau einer umfassenden Soft-Error-aware-Datenbank für eine gegebene digitale Bibliothek und eines umfassenden mehrstufigen strahlungsharten Designflusses dienen, der mit den Standard-IC-Designtools implementiert werden kann. Im nächsten Schritt werden die mit den Bestrahlungsexperimenten erzielten Ergebnisse ausgewertet. KW - Single Event Transient KW - radiation hardness design KW - Single Event Transient KW - Strahlungshärte Entwurf Y1 - 2022 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-534843 ER - TY - JOUR A1 - Ramezani Ziarani, Maryam A1 - Bookhagen, Bodo A1 - Schmidt, Torsten A1 - Wickert, Jens A1 - de la Torre, Alejandro A1 - Deng, Zhiguo A1 - Calori, Andrea T1 - A model for the relationship between rainfall, GNSS-derived integrated water vapour, and CAPE in the eastern central Andes JF - Remote Sensing N2 - Atmospheric water vapour content is a key variable that controls the development of deep convective storms and rainfall extremes over the central Andes. Direct measurements of water vapour are challenging; however, recent developments in microwave processing allow the use of phase delays from L-band radar to measure the water vapour content throughout the atmosphere: Global Navigation Satellite System (GNSS)-based integrated water vapour (IWV) monitoring shows promising results to measure vertically integrated water vapour at high temporal resolutions. Previous works also identified convective available potential energy (CAPE) as a key climatic variable for the formation of deep convective storms and rainfall in the central Andes. Our analysis relies on GNSS data from the Argentine Continuous Satellite Monitoring Network, Red Argentina de Monitoreo Satelital Continuo (RAMSAC) network from 1999 to 2013. CAPE is derived from version 2.0 of the ECMWF’s (European Centre for Medium-Range Weather Forecasts) Re-Analysis (ERA-interim) and rainfall from the TRMM (Tropical Rainfall Measuring Mission) product. In this study, we first analyse the rainfall characteristics of two GNSS-IWV stations by comparing their complementary cumulative distribution function (CCDF). Second, we separately derive the relation between rainfall vs. CAPE and GNSS-IWV. Based on our distribution fitting analysis, we observe an exponential relation of rainfall to GNSS-IWV. In contrast, we report a power-law relationship between the daily mean value of rainfall and CAPE at the GNSS-IWV station locations in the eastern central Andes that is close to the theoretical relationship based on parcel theory. Third, we generate a joint regression model through a multivariable regression analysis using CAPE and GNSS-IWV to explain the contribution of both variables in the presence of each other to extreme rainfall during the austral summer season. We found that rainfall can be characterised with a higher statistical significance for higher rainfall quantiles, e.g., the 0.9 quantile based on goodness-of-fit criterion for quantile regression. We observed different contributions of CAPE and GNSS-IWV to rainfall for each station for the 0.9 quantile. Fourth, we identify the temporal relation between extreme rainfall (the 90th, 95th, and 99th percentiles) and both GNSS-IWV and CAPE at 6 h time steps. We observed an increase before the rainfall event and at the time of peak rainfall—both for GNSS-integrated water vapour and CAPE. We show higher values of CAPE and GNSS-IWV for higher rainfall percentiles (99th and 95th percentiles) compared to the 90th percentile at a 6-h temporal scale. Based on our correlation analyses and the dynamics of the time series, we show that both GNSS-IWV and CAPE had comparable magnitudes, and we argue to consider both climatic variables when investigating their effect on rainfall extremes. KW - Global Navigation Satellite System (GNSS) KW - GNSS-integrated water vapour KW - convective available potential energy (CAPE) KW - extreme rainfall KW - TRMM Y1 - 2021 U6 - https://doi.org/10.3390/rs13183788 SN - 2072-4292 VL - 13 IS - 18 PB - MDPI CY - Basel ER - TY - GEN A1 - Ramezani Ziarani, Maryam A1 - Bookhagen, Bodo A1 - Schmidt, Torsten A1 - Wickert, Jens A1 - de la Torre, Alejandro A1 - Deng, Zhiguo A1 - Calori, Andrea T1 - A model for the relationship between rainfall, GNSS-derived integrated water vapour, and CAPE in the eastern central Andes T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - Atmospheric water vapour content is a key variable that controls the development of deep convective storms and rainfall extremes over the central Andes. Direct measurements of water vapour are challenging; however, recent developments in microwave processing allow the use of phase delays from L-band radar to measure the water vapour content throughout the atmosphere: Global Navigation Satellite System (GNSS)-based integrated water vapour (IWV) monitoring shows promising results to measure vertically integrated water vapour at high temporal resolutions. Previous works also identified convective available potential energy (CAPE) as a key climatic variable for the formation of deep convective storms and rainfall in the central Andes. Our analysis relies on GNSS data from the Argentine Continuous Satellite Monitoring Network, Red Argentina de Monitoreo Satelital Continuo (RAMSAC) network from 1999 to 2013. CAPE is derived from version 2.0 of the ECMWF’s (European Centre for Medium-Range Weather Forecasts) Re-Analysis (ERA-interim) and rainfall from the TRMM (Tropical Rainfall Measuring Mission) product. In this study, we first analyse the rainfall characteristics of two GNSS-IWV stations by comparing their complementary cumulative distribution function (CCDF). Second, we separately derive the relation between rainfall vs. CAPE and GNSS-IWV. Based on our distribution fitting analysis, we observe an exponential relation of rainfall to GNSS-IWV. In contrast, we report a power-law relationship between the daily mean value of rainfall and CAPE at the GNSS-IWV station locations in the eastern central Andes that is close to the theoretical relationship based on parcel theory. Third, we generate a joint regression model through a multivariable regression analysis using CAPE and GNSS-IWV to explain the contribution of both variables in the presence of each other to extreme rainfall during the austral summer season. We found that rainfall can be characterised with a higher statistical significance for higher rainfall quantiles, e.g., the 0.9 quantile based on goodness-of-fit criterion for quantile regression. We observed different contributions of CAPE and GNSS-IWV to rainfall for each station for the 0.9 quantile. Fourth, we identify the temporal relation between extreme rainfall (the 90th, 95th, and 99th percentiles) and both GNSS-IWV and CAPE at 6 h time steps. We observed an increase before the rainfall event and at the time of peak rainfall—both for GNSS-integrated water vapour and CAPE. We show higher values of CAPE and GNSS-IWV for higher rainfall percentiles (99th and 95th percentiles) compared to the 90th percentile at a 6-h temporal scale. Based on our correlation analyses and the dynamics of the time series, we show that both GNSS-IWV and CAPE had comparable magnitudes, and we argue to consider both climatic variables when investigating their effect on rainfall extremes. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1172 KW - Global Navigation Satellite System (GNSS) KW - GNSS-integrated water vapour KW - convective available potential energy (CAPE) KW - extreme rainfall KW - TRMM Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-523256 SN - 1866-8372 IS - 1172 ER - TY - JOUR A1 - Grebenkov, Denis S. A1 - Metzler, Ralf A1 - Oshanin, Gleb T1 - A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes JF - New Journal of Physics (NJP) N2 - We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction setting encountered in diverse molecular biology systems, in which, e.g. a signal transduction proceeds via a series of consecutive 'messengers': the first messenger has to find its respective immobile target site triggering a launch of the second messenger, the second messenger seeks its own target site and provokes a launch of the third messenger and so on, resembling a relay race in human competitions. For such a molecular relay race taking place in infinite one-, two- and three-dimensional systems, we find exact expressions for the probability density function of the time instant of the terminal reaction event, conditioned on preceding successful reaction events on an ordered array of target sites. The obtained expressions pertain to the most general conditions: number of intermediate stages and the corresponding diffusion coefficients, the sizes of the target sites, the distances between them, as well as their reactivities are arbitrary. KW - diffusion KW - reaction cascade KW - first passage time Y1 - 2021 U6 - https://doi.org/10.1088/1367-2630/ac1e42 SN - 1367-2630 VL - 23 PB - IOP - Institute of Physics Publishing CY - Bristol ER - TY - GEN A1 - Grebenkov, Denis S. A1 - Metzler, Ralf A1 - Oshanin, Gleb T1 - A molecular relay race: sequential first-passage events to the terminal reaction centre in a cascade of diffusion controlled processes T2 - Postprints der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe N2 - We consider a sequential cascade of molecular first-reaction events towards a terminal reaction centre in which each reaction step is controlled by diffusive motion of the particles. The model studied here represents a typical reaction setting encountered in diverse molecular biology systems, in which, e.g. a signal transduction proceeds via a series of consecutive 'messengers': the first messenger has to find its respective immobile target site triggering a launch of the second messenger, the second messenger seeks its own target site and provokes a launch of the third messenger and so on, resembling a relay race in human competitions. For such a molecular relay race taking place in infinite one-, two- and three-dimensional systems, we find exact expressions for the probability density function of the time instant of the terminal reaction event, conditioned on preceding successful reaction events on an ordered array of target sites. The obtained expressions pertain to the most general conditions: number of intermediate stages and the corresponding diffusion coefficients, the sizes of the target sites, the distances between them, as well as their reactivities are arbitrary. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1159 KW - diffusion KW - reaction cascade KW - first passage time Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-521942 SN - 1866-8372 ER - TY - JOUR A1 - Perach, Shai A1 - Alexandron, Giora T1 - A MOOC-Based Computer Science Program for Middle School BT - Results, Challenges, and the Covid-19 Effect JF - EMOOCs 2021 N2 - In an attempt to pave the way for more extensive Computer Science Education (CSE) coverage in K-12, this research developed and made a preliminary evaluation of a blended-learning Introduction to CS program based on an academic MOOC. Using an academic MOOC that is pedagogically effective and engaging, such a program may provide teachers with disciplinary scaffolds and allow them to focus their attention on enhancing students’ learning experience and nurturing critical 21st-century skills such as self-regulated learning. As we demonstrate, this enabled us to introduce an academic level course to middle-school students. In this research, we developed the principals and initial version of such a program, targeting ninth-graders in science-track classes who learn CS as part of their standard curriculum. We found that the middle-schoolers who participated in the program achieved academic results on par with undergraduate students taking this MOOC for academic credit. Participating students also developed a more accurate perception of the essence of CS as a scientific discipline. The unplanned school closure due to the COVID19 pandemic outbreak challenged the research but underlined the advantages of such a MOOCbased blended learning program above classic pedagogy in times of global or local crises that lead to school closure. While most of the science track classes seem to stop learning CS almost entirely, and the end-of-year MoE exam was discarded, the program’s classes smoothly moved to remote learning mode, and students continued to study at a pace similar to that experienced before the school shut down. Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-517133 SN - 978-3-86956-512-5 VL - 2021 SP - 111 EP - 127 PB - Universitätsverlag Potsdam CY - Potsdam ER - TY - THES A1 - Zass, Alexander T1 - A multifaceted study of marked Gibbs point processes T1 - Facetten von markierten Gibbsschen Punktprozessen N2 - This thesis focuses on the study of marked Gibbs point processes, in particular presenting some results on their existence and uniqueness, with ideas and techniques drawn from different areas of statistical mechanics: the entropy method from large deviations theory, cluster expansion and the Kirkwood--Salsburg equations, the Dobrushin contraction principle and disagreement percolation. We first present an existence result for infinite-volume marked Gibbs point processes. More precisely, we use the so-called entropy method (and large-deviation tools) to construct marked Gibbs point processes in R^d under quite general assumptions. In particular, the random marks belong to a general normed space S and are not bounded. Moreover, we allow for interaction functionals that may be unbounded and whose range is finite but random. The entropy method relies on showing that a family of finite-volume Gibbs point processes belongs to sequentially compact entropy level sets, and is therefore tight. We then present infinite-dimensional Langevin diffusions, that we put in interaction via a Gibbsian description. In this setting, we are able to adapt the general result above to show the existence of the associated infinite-volume measure. We also study its correlation functions via cluster expansion techniques, and obtain the uniqueness of the Gibbs process for all inverse temperatures β and activities z below a certain threshold. This method relies in first showing that the correlation functions of the process satisfy a so-called Ruelle bound, and then using it to solve a fixed point problem in an appropriate Banach space. The uniqueness domain we obtain consists then of the model parameters z and β for which such a problem has exactly one solution. Finally, we explore further the question of uniqueness of infinite-volume Gibbs point processes on R^d, in the unmarked setting. We present, in the context of repulsive interactions with a hard-core component, a novel approach to uniqueness by applying the discrete Dobrushin criterion to the continuum framework. We first fix a discretisation parameter a>0 and then study the behaviour of the uniqueness domain as a goes to 0. With this technique we are able to obtain explicit thresholds for the parameters z and β, which we then compare to existing results coming from the different methods of cluster expansion and disagreement percolation. Throughout this thesis, we illustrate our theoretical results with various examples both from classical statistical mechanics and stochastic geometry. N2 - Diese Arbeit konzentriert sich auf die Untersuchung von markierten Gibbs-Punkt-Prozessen und stellt insbesondere einige Ergebnisse zu deren Existenz und Eindeutigkeit vor. Dabei werden Ideen und Techniken aus verschiedenen Bereichen der statistischen Mechanik verwendet: die Entropie-Methode aus der Theorie der großen Abweichungen, die Cluster-Expansion und die Kirkwood-Salsburg-Gleichungen, das Dobrushin-Kontraktionsprinzip und die Disagreement-Perkolation. Wir präsentieren zunächst ein Existenzergebnis für unendlich-volumige markierte Gibbs-Punkt-Prozesse. Genauer gesagt verwenden wir die sogenannte Entropie-Methode (und Werkzeuge der großen Abweichung), um markierte Gibbs-Punkt-Prozesse in R^d unter möglichst allgemeinen Annahmen zu konstruieren. Insbesondere gehören die zufälligen Markierungen zu einem allgemeinen normierten Raum und sind nicht beschränkt. Außerdem lassen wir Interaktionsfunktionale zu, die unbeschränkt sein können und deren Reichweite endlich, aber zufällig ist. Die Entropie-Methode beruht darauf, zu zeigen, dass eine Familie von endlich-volumigen Gibbs-Punkt-Prozessen zu sequentiell kompakten Entropie-Niveau-Mengen gehört, und daher dicht ist. Wir stellen dann unendlich-dimensionale Langevin-Diffusionen vor, die wir über eine Gibbssche Beschreibung in Wechselwirkung setzen. In dieser Umgebung sind wir in der Lage, das vorangehend vorgestellte allgemeine Ergebnis anzupassen, um die Existenz des zugehörigen unendlich-dimensionalen Maßes zu zeigen. Wir untersuchen auch seine Korrelationsfunktionen über Cluster-Expansions Techniken und erhalten die Eindeutigkeit des Gibbs-Prozesses für alle inversen Temperaturen β und Aktivitäten z unterhalb einer bestimmten Schwelle. Diese Methode beruht darauf, zunächst zu zeigen, dass die Korrelationsfunktionen des Prozesses eine so genannte Ruelle-Schranke erfüllen, um diese dann zur Lösung eines Fixpunktproblems in einem geeigneten Banach-Raum zu verwenden. Der Eindeutigkeitsbereich, den wir erhalten, wird dann aus den Modellparametern z und β definiert, für die ein solches Problem genau eine Lösung hat. Schließlich untersuchen wir die Frage nach der Eindeutigkeit von unendlich-volumigen Gibbs-Punkt-Prozessen auf R^d im unmarkierten Fall weiter. Im Zusammenhang mit repulsiven Wechselwirkungen basierend auf einer Hartkernkomponente stellen wir einen neuen Ansatz zur Eindeutigkeit vor, indem wir das diskrete Dobrushin-Kriterium im kontinuierlichen Rahmen anwenden. Wir legen zunächst einen Diskretisierungsparameter a>0 fest und untersuchen dann das Verhalten des Bereichs der Eindeutigkeit, wenn a gegen 0 geht. Mit dieser Technik sind wir in der Lage, explizite Schwellenwerte für die Parameter z und β zu erhalten, die wir dann mit bestehenden Ergebnissen aus den verschiedenen Methoden der Cluster-Expansion und der Disagreement-Perkolation vergleichen. In dieser Arbeit illustrieren wir unsere theoretischen Ergebnisse mit verschiedenen Beispielen sowohl aus der klassischen statistischen Mechanik als auch aus der stochastischen Geometrie. KW - marked Gibbs point processes KW - Langevin diffusions KW - Dobrushin criterion KW - Entropy method KW - Cluster expansion KW - Kirkwood--Salsburg equations KW - DLR equations KW - Markierte Gibbs-Punkt-Prozesse KW - Entropiemethode KW - Cluster-Expansion KW - DLR-Gleichungen KW - Dobrushin-Kriterium KW - Kirkwood-Salsburg-Gleichungen KW - Langevin-Diffusions Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-512775 ER - TY - JOUR A1 - Navarro, Marisa A1 - Orejas, Fernando A1 - Pino, Elvira A1 - Lambers, Leen T1 - A navigational logic for reasoning about graph properties JF - Journal of logical and algebraic methods in programming N2 - Graphs play an important role in many areas of Computer Science. In particular, our work is motivated by model-driven software development and by graph databases. For this reason, it is very important to have the means to express and to reason about the properties that a given graph may satisfy. With this aim, in this paper we present a visual logic that allows us to describe graph properties, including navigational properties, i.e., properties about the paths in a graph. The logic is equipped with a deductive tableau method that we have proved to be sound and complete. KW - Graph logic KW - Algebraic methods KW - Formal modelling KW - Specification Y1 - 2021 U6 - https://doi.org/10.1016/j.jlamp.2020.100616 SN - 2352-2208 SN - 2352-2216 VL - 118 PB - Elsevier Science CY - Amsterdam [u.a.] ER - TY - JOUR A1 - McNamara, James T1 - A new edition of tacitus Germania BT - Rezension zu: Germania / Tacito ; saggio introduttivo, nuova traduzzione e note a cura di Sergio Audano. - Santarcangelo di Romagna: Rusconi Libri, 2020. - CXCVIII, 180 S. - ISBN: 978-88-18-03633-6 JF - The classical review / Classical Association Y1 - 2021 SN - 978-88-18-03633-6 U6 - https://doi.org/10.1017/S0009840X21002110 SN - 0009-840X SN - 1464-3561 VL - 71 IS - 2 SP - 418 EP - 420 PB - Cambridge Univ. Press CY - Cambridge ER - TY - JOUR A1 - Kindermann, Liana A1 - Dobler, Magnus A1 - Niedeggen, Daniela A1 - Linstädter, Anja T1 - A new protocol for estimation of woody aboveground biomass in disturbance-prone ecosystems JF - Ecological indicators : integrating monitoring, assessment and management N2 - Almost one third of global drylands are open forests and savannas, which are typically shaped by frequent natural disturbances such as wildfire and herbivory. Studies on ecosystem functions and services of woody vegetation require robust estimates of aboveground biomass (AGB). However, most methods have been developed for comparatively undisturbed forest ecosystems. As they are not tailored to accurately quantify AGB of small and irregular growth forms, their application on these growth forms may lead to unreliable or even biased AGB estimates in disturbance-prone dryland ecosystems. Moreover, these methods cannot quantify AGB losses caused by disturbance agents. Here we propose a methodology to estimate individual-and stand-level woody AGB in disturbance-prone ecosystems. It consists of flexible field sampling routines and estimation workflows for six growth classes, delineated by size and damage criteria. It also comprises a detailed damage assessment, harnessing the ecological archive of woody growth for past disturbances. Based on large inventories collected along steep gradients of elephant disturbances in African dryland ecosystems, we compared the AGB estimates generated with our proposed method against estimates from a less adapted forest inventory method. We evaluated the necessary stepwise procedures of method adaptation and analyzed each step's effect on stand-level AGB estimation. We further explored additional advantages of our proposed method with regard to disturbance impact quantification. Results indicate that a majority of growth forms and individuals in savanna vegetation could only be assessed if methods of AGB estimation were adapted to the conditions of a disturbance-prone ecosystem. Furthermore, our damage assessment demonstrated that one third to half of all woody AGB was lost to disturbances. Consequently, less adapted methods may be insufficient and are likely to render inaccurate AGB estimations. Our proposed method has the potential to accurately quantify woody AGB in disturbance-prone ecosystems, as well as AGB losses. Our method is more time consuming than conventional allometric approaches, yet it can cover sufficient areas within reasonable timespans, and can also be easily adapted to alternative sampling schemes. KW - Damage assessment KW - Disturbance impacts KW - Tree growth classes KW - Method KW - comparison KW - Flexible sampling strategy KW - Tree allometry KW - Woody KW - aboveground biomass Y1 - 2021 U6 - https://doi.org/10.1016/j.ecolind.2021.108466 SN - 1470-160X SN - 1872-7034 VL - 135 PB - Elsevier CY - Amsterdam ER - TY - GEN A1 - Göthel, Markus A1 - Listek, Martin A1 - Messerschmidt, Katrin A1 - Schlör, Anja A1 - Hönow, Anja A1 - Hanack, Katja T1 - A New Workflow to Generate Monoclonal Antibodies against Microorganisms T2 - Mathematisch-Naturwissenschaftliche Reihe N2 - Monoclonal antibodies are used worldwide as highly potent and efficient detection reagents for research and diagnostic applications. Nevertheless, the specific targeting of complex antigens such as whole microorganisms remains a challenge. To provide a comprehensive workflow, we combined bioinformatic analyses with novel immunization and selection tools to design monoclonal antibodies for the detection of whole microorganisms. In our initial study, we used the human pathogenic strain E. coli O157:H7 as a model target and identified 53 potential protein candidates by using reverse vaccinology methodology. Five different peptide epitopes were selected for immunization using epitope-engineered viral proteins. The identification of antibody-producing hybridomas was performed by using a novel screening technology based on transgenic fusion cell lines. Using an artificial cell surface receptor expressed by all hybridomas, the desired antigen-specific cells can be sorted fast and efficiently out of the fusion cell pool. Selected antibody candidates were characterized and showed strong binding to the target strain E. coli O157:H7 with minor or no cross-reactivity to other relevant microorganisms such as Legionella pneumophila and Bacillus ssp. This approach could be useful as a highly efficient workflow for the generation of antibodies against microorganisms. T3 - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 1174 KW - monoclonal antibody KW - antibody producing cell selection KW - hybridoma KW - epitope prediction Y1 - 2021 U6 - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-523341 SN - 1866-8372 IS - 20 ER -