TY  - GEN
A1  - Pacholski, Claudia
A1  - Agarwal, Vivechana
A1  - Balderas-Valadez, Ruth Fabiola
T1  - Fabrication of porous silicon-based optical sensors using metal-assisted chemical etching
N2  - Optical biosensors based on porous silicon were fabricated by metal assisted chemical etching. Thereby double layered porous silicon structures were obtained consisting of porous pillars with large pores on top of a porous silicon layer with smaller pores. These structures showed a similar sensing performance in comparison to electrochemically produced porous silicon interferometric sensors.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 316 
KW  - fourier-transform spectroscopy
KW  - nanostructures
KW  - nanowires
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-394426
SP  - 21430
EP  - 21434
ER  - 
TY  - GEN
A1  - Olejko, Lydia
A1  - Cywiński, P. J.
A1  - Bald, Ilko
T1  - An ion-controlled four-color fluorescent telomeric switch on DNA origami structures
N2  - The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using Förster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter.
T3  - Zweitveröffentlichungen der Universität Potsdam : Mathematisch-Naturwissenschaftliche Reihe - 254 
KW  - resonance energy-transfer
KW  - g-quadruplex
KW  - quantum dots
KW  - strand breakage
KW  - photonic wires
KW  - 3-color fret
KW  - nanostructures
KW  - recognition
KW  - sensitivity
KW  - assemblies
Y1  - 2016
U6  - http://nbn-resolving.de/urn/resolver.pl?urn:nbn:de:kobv:517-opus4-95831
SP  - 10339
EP  - 10347
ER  - 
TY  - JOUR
A1  - Olejko, Lydia
A1  - Cywiński, Piotr J.
A1  - Bald, Ilko
T1  - An ion-controlled four-color fluorescent telomeric switch on DNA origami structures
JF  - Nanoscale
N2  - The folding of single-stranded telomeric DNA into guanine (G) quadruplexes is a conformational change that plays a major role in sensing and drug targeting. The telomeric DNA can be placed on DNA origami nanostructures to make the folding process extremely selective for K+ ions even in the presence of high Na+ concentrations. Here, we demonstrate that the K+-selective G-quadruplex formation is reversible when using a cryptand to remove K+ from the G-quadruplex. We present a full characterization of the reversible switching between single-stranded telomeric DNA and G-quadruplex structures using Förster resonance energy transfer (FRET) between the dyes fluorescein (FAM) and cyanine3 (Cy3). When attached to the DNA origami platform, the G-quadruplex switch can be incorporated into more complex photonic networks, which is demonstrated for a three-color and a four-color FRET cascade from FAM over Cy3 and Cy5 to IRDye700 with G-quadruplex-Cy3 acting as a switchable transmitter.
KW  - resonance energy-transfer
KW  - g-quadruplex
KW  - quantum dots
KW  - strand breakage
KW  - photonic wires
KW  - 3-color fret
KW  - nanostructures
KW  - recognition
KW  - sensitivity
KW  - assemblies
Y1  - 2016
U6  - https://doi.org/10.1039/C6NR00119J
SN  - 2040-3372
SN  - 2040-3364
VL  - 8
SP  - 10339
EP  - 10347
PB  - RSC Publ.
CY  - Cambridge
ER  -